Oligosaccharides

• 

  Subject Areas on Research

  • A comparison of the fine saccharide-binding specificity of Dioclea grandiflora lectin and concanavalin A. 
  • A simple sample preparation for enhancing the sensitivity of mass spectrometric oligosaccharide determinations through the use of an adsorptive hydrophobic resin. 
  • Adherence of bacteria to mammalian cells: inhibition by tunicamycin and streptovirudin. 
  • Altered fine structures of corneal and skeletal keratan sulfate and chondroitin/dermatan sulfate in macular corneal dystrophy. 
  • Analysis of a glucose tetrasaccharide elevated in Pompe disease by stable isotope dilution-electrospray ionization tandem mass spectrometry. 
  • Analysis of the binding specificities of oligomannoside-binding proteins using methylated monosaccharides. 
  • Analysis of ubiquinones, dolichols, and dolichol diphosphate-oligosaccharides by liquid chromatography-electrospray ionization-mass spectrometry. 
  • Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus. 
  • Assembling Glycan-Charged Dolichol Phosphates: Chemoenzymatic Synthesis of a Haloferax volcanii N-Glycosylation Pathway Intermediate. 
  • Assembly and maturation of HLA-A and HLA-B antigens in vivo. 
  • Assessing disease severity in Pompe disease: the roles of a urinary glucose tetrasaccharide biomarker and imaging techniques. 
  • Biochemical mass spectrometry: worth the weight? 
  • Bypassing complement: evolutionary lessons and future implications. 
  • CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. 
  • Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities. 
  • Characterization of a novel family of ciliary body glycoproteins. 
  • Characterization of xenoreactive natural antibodies: interactions with carbohydrate determinants. 
  • Chemical characterization of oligosaccharides in the milk of six species of New and Old World monkeys. 
  • Comparison of the hydrophobic properties of Candida albicans and Candida dubliniensis. 
  • Conformational analysis of a flexible oligosaccharide using residual dipolar couplings. 
  • Differences in the acid-labile component of Candida albicans mannan from hydrophobic and hydrophilic yeast cells. 
  • Differential recognition by proteins of alpha-galactosyl residues on endothelial cell surfaces. 
  • Distinct glycan-charged phosphodolichol carriers are required for the assembly of the pentasaccharide N-linked to the Haloferax volcanii S-layer glycoprotein. 
  • Effect of monosaccharide composition, glycosidic linkage position and anomericity on the electrophoretic mobility of labeled oligosaccharides. 
  • Energetics of lectin-carbohydrate binding. A microcalorimetric investigation of concanavalin A-oligomannoside complexation. 
  • Erythrocyte blood group antigens: polymorphisms of functionally important molecules. 
  • Evidence for processing of dolichol-linked oligosaccharides in patients with neuronal ceroid-lipofuscinosis. 
  • Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. 
  • Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease. 
  • Heparin binding induces a conformational change in pigment epithelium-derived factor. 
  • Heparin oligosaccharides enhance tissue-type plasminogen activator: a correlation between oligosaccharide length and stimulation of plasminogen activation. 
  • Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1 leads to 3 N-acetylglucosamine linkages. 
  • Hyaluronidase activity of alveolar macrophages. 
  • Identification of sialyl Lewis-x in squamous cell carcinoma of the head and neck. 
  • Influence of outer region mannosylphosphorylation on N-glycan formation by Candida albicans: normal acid-stable N-glycan formation requires acid-labile mannosylphosphate addition. 
  • Inhibition of protein synthesis also inhibits synthesis of lipid-linked oligosaccharides. 
  • Invited commentary. 
  • Lactotetraose series ganglioside 3',6'-isoLD1 in tumors of central nervous and other systems in vitro and in vivo. 
  • Liquid chromatographic assay for a glucose tetrasaccharide, a putative biomarker for the diagnosis of Pompe disease. 
  • Liver fibrosis during clinical ascertainment of glycogen storage disease type III: a need for improved and systematic monitoring. 
  • Long-term monitoring of patients with infantile-onset Pompe disease on enzyme replacement therapy using a urinary glucose tetrasaccharide biomarker. 
  • Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation. 
  • Mapping bacterial glycolipid complexity using capillary electrophoresis and electrospray mass spectrometry. 
  • Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer. 
  • N-Linked Glycans Are Assembled on Highly Reduced Dolichol Phosphate Carriers in the Hyperthermophilic Archaea Pyrococcus furiosus. 
  • Pharmacology of pertussis toxin B-oligomer. 
  • Platelets induce sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver. 
  • Posttranslational modifications of human inter-alpha-inhibitor: identification of glycans and disulfide bridges in heavy chains 1 and 2. 
  • Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. 
  • Protein glycosylation as an adaptive response in Archaea: growth at different salt concentrations leads to alterations in Haloferax volcanii S-layer glycoprotein N-glycosylation. 
  • Purification and characterization of GDP-L-fucose-N-acetyl beta-D-glucosaminide alpha 1----6fucosyltransferase from cultured human skin fibroblasts. Requirement of a specific biantennary oligosaccharide as substrate. 
  • Purification of glycopeptides of human plasma proteins by high-performance liquid chromatography. 
  • Quantitative computed tomography for enzyme replacement therapy in Pompe disease. 
  • Retinal ligatin recognizes glycoproteins bearing oligosaccharides terminating in phosphodiester-linked glucose. 
  • Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1. 
  • SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. 
  • Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap. 
  • Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition. 
  • Structural analysis of semi-specific oligosaccharide recognition by a cellulose-binding protein of thermotoga maritima reveals adaptations for functional diversification of the oligopeptide periplasmic binding protein fold. 
  • Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe disease. 
  • Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. 
  • The carbohydrates in frog retinal rod outer segments. 
  • The cluster glycoside effect. 
  • The cutaneous lymphocyte antigen is an essential component of the L-selectin ligand induced on human vascular endothelial cells. 
  • The role of hyaluronan degradation products as innate alloimmune agonists. 
  • Thermodynamics of hydrolysis of oligosaccharides. 
  • Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells. 
  • Tunable leuko-polymersomes that adhere specifically to inflammatory markers. 
• 

  Keywords of People

  • Case, Laura Elizabeth, Associate Professor in Orthopaedic Surgery, Orthopaedics, Physical Therapy
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology