Oligosaccharides

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  Subject Areas on Research

  • A comparison of the fine saccharide-binding specificity of Dioclea grandiflora lectin and concanavalin A. 
  • Analysis of a glucose tetrasaccharide elevated in Pompe disease by stable isotope dilution-electrospray ionization tandem mass spectrometry. 
  • Analysis of the binding specificities of oligomannoside-binding proteins using methylated monosaccharides. 
  • Analysis of ubiquinones, dolichols, and dolichol diphosphate-oligosaccharides by liquid chromatography-electrospray ionization-mass spectrometry. 
  • Assembling Glycan-Charged Dolichol Phosphates: Chemoenzymatic Synthesis of a Haloferax volcanii N-Glycosylation Pathway Intermediate. 
  • Assembly and maturation of HLA-A and HLA-B antigens in vivo. 
  • Assessing disease severity in Pompe disease: the roles of a urinary glucose tetrasaccharide biomarker and imaging techniques. 
  • Bypassing complement: evolutionary lessons and future implications. 
  • CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. 
  • Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities. 
  • Characterization of a novel family of ciliary body glycoproteins. 
  • Characterization of xenoreactive natural antibodies: interactions with carbohydrate determinants. 
  • Chemical characterization of oligosaccharides in the milk of six species of New and Old World monkeys. 
  • Conformational analysis of a flexible oligosaccharide using residual dipolar couplings. 
  • Differential recognition by proteins of alpha-galactosyl residues on endothelial cell surfaces. 
  • Distinct glycan-charged phosphodolichol carriers are required for the assembly of the pentasaccharide N-linked to the Haloferax volcanii S-layer glycoprotein. 
  • Energetics of lectin-carbohydrate binding. A microcalorimetric investigation of concanavalin A-oligomannoside complexation. 
  • Erythrocyte blood group antigens: polymorphisms of functionally important molecules. 
  • Evidence for processing of dolichol-linked oligosaccharides in patients with neuronal ceroid-lipofuscinosis. 
  • Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. 
  • Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease. 
  • Heparin oligosaccharides enhance tissue-type plasminogen activator: a correlation between oligosaccharide length and stimulation of plasminogen activation. 
  • Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1 leads to 3 N-acetylglucosamine linkages. 
  • Lactotetraose series ganglioside 3',6'-isoLD1 in tumors of central nervous and other systems in vitro and in vivo. 
  • Liquid chromatographic assay for a glucose tetrasaccharide, a putative biomarker for the diagnosis of Pompe disease. 
  • Long-term monitoring of patients with infantile-onset Pompe disease on enzyme replacement therapy using a urinary glucose tetrasaccharide biomarker. 
  • Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation. 
  • N-Linked Glycans Are Assembled on Highly Reduced Dolichol Phosphate Carriers in the Hyperthermophilic Archaea Pyrococcus furiosus. 
  • Pharmacology of pertussis toxin B-oligomer. 
  • Platelets induce sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver. 
  • Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. 
  • Protein glycosylation as an adaptive response in Archaea: growth at different salt concentrations leads to alterations in Haloferax volcanii S-layer glycoprotein N-glycosylation. 
  • Purification of glycopeptides of human plasma proteins by high-performance liquid chromatography. 
  • Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1. 
  • SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. 
  • Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap. 
  • Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition. 
  • Structural analysis of semi-specific oligosaccharide recognition by a cellulose-binding protein of thermotoga maritima reveals adaptations for functional diversification of the oligopeptide periplasmic binding protein fold. 
  • Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe disease. 
  • Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. 
  • The carbohydrates in frog retinal rod outer segments. 
  • The cluster glycoside effect. 
  • The cutaneous lymphocyte antigen is an essential component of the L-selectin ligand induced on human vascular endothelial cells. 
  • The role of hyaluronan degradation products as innate alloimmune agonists. 
  • Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells. 
  • Tunable leuko-polymersomes that adhere specifically to inflammatory markers. 
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  Keywords of People

  • Case, Laura Elizabeth, Assistant Professor of Orthopaedic Surgery, Orthopaedics, Physical Therapy
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology