Organoids
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Subject Areas on Research
- A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology.
- A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities.
- A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo.
- Alteration by methadone of catecholamine uptake and release in isolated rat adrenomedullary storage vesicles.
- An early cell shape transition drives evolutionary expansion of the human forebrain.
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer.
- Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia.
- BALO: a "mini lung" model to study cell-cell interactions.
- Blast cell leukemia with IgM monoclonal gammopathy and intracytoplasmic vacuoles and Auer-body-like inclusions.
- Breakthrough Moments: Genome Editing and Organoids.
- Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells.
- Caspase-7 activates ASM to repair gasdermin and perforin pores.
- Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine.
- Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation.
- Compartmental analysis of amine storage in bovine adrenal medullary granules.
- Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia.
- Effect of vanadate on intracellular distribution and function of 10-nm filaments.
- Engineering functional 3-dimensional patient-derived endocrine organoids for broad multiplatform applications.
- Enhanced Neuronal Activity and Asynchronous Calcium Transients Revealed in a 3D Organoid Model of Alzheimer's Disease.
- Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner.
- Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution.
- Establishment of patient-derived organoid models of lower-grade glioma.
- Fibrillar systems in cell motility.
- Founder cells shape brain evolution.
- Functions of cytoplasmic fibers in intracellular movements in BHK-21 cells.
- Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
- Gut organoids: mini-tissues in culture to study intestinal physiology and disease.
- Harnessing developmental plasticity to pattern kidney organoids
- High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
- Human distal lung maps and lineage hierarchies reveal a bipotent progenitor.
- Human lung organoids as a model for respiratory virus replication and countermeasure performance in human hosts.
- Human organoids: a new dimension in cell biology.
- In vitro models of the human endometrium: evolution and application for women's health.
- Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface.
- Interleukin-13 disrupts type 2 pneumocyte stem cell activity.
- Iron metabolism and cell membranes. III. Iron-induced alterations in HeLa cells.
- JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.
- Light microscopic quantitation of the endothelial vacuoles in Schlemm's canal.
- Localization of calmodulin in rat cerebellum by immunoelectron microscopy.
- Lung organoids: current uses and future promise.
- Mesenchymal stem cells support growth and organization of host-liver colorectal-tumor organoids and possibly resistance to chemotherapy.
- Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age.
- Modulation of sulfur assimilation metabolic toxicity overcomes anemia and hemochromatosis in mice.
- Morphology of rabbit collecting duct.
- Morphology of the buccopharyngeal portion of the gill in the fathead minnow Pimephales promelas (Rafinesque).
- Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
- PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo.
- Patient-derived micro-organospheres enable clinical precision oncology.
- Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
- Presence and indirect immunofluorescent localization of calmodulin in Paramecium tetraurelia.
- Progesterone Signaling in Endometrial Epithelial Organoids.
- Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay.
- Rapid tissue prototyping with micro-organospheres.
- Regulation of the cytoskeleton by Ca2+-calmodulin and cAMP.
- Relationship between movement and aggregation of centrioles in syncytia and formation of microtubule bundles.
- Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates.
- Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids.
- Scanning and transmission electron microscopy of human prostatic acinar cells.
- Self-renewing endometrial epithelial organoids of the human uterus.
- Stem Cell-Derived Models of Viral Infections in the Gastrointestinal Tract.
- Subcellular changes in capillary endothelial cells during repair of hyperoxic lung injury.
- The Estrogen Receptor α Cistrome in Human Endometrium and Epithelial Organoids.
- The Ethics of Experimenting With Human Brain Tissue
- The bushy cells in the anteroventral cochlear nucleus of the cat. A study with the electron microscope.
- Three-dimensional reconstruction and quantitative analysis of rat lung type II cells: a computer-based study.
- Toward improved understanding of cardiac development and congenital heart disease: The advent of cardiac organoids.
- Transcriptome and epigenome landscape of human cortical development modeled in organoids.
- Tropism of SARS-CoV-2 for human cortical astrocytes.
- Uptake, storage, and distribution of amines in bovine adrenal medullary vesicles.
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Keywords of People
- Bradford, William Dalton, Professor of Pathology, Pathology
- Coyne, Carolyn, George Barth Geller Distinguished Professor of Immunology, Cell Biology
- Silver, Debra Lynn, Associate Professor of Molecular Genetics and Microbiology, Duke Science & Society
- Tata, Purushothama Rao, Assistant Professor of Cell Biology, Cell Biology