Organometallic Compounds

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  Subject Areas on Research

  • "Keyhole" method for accelerating imaging of contrast agent uptake. 
  • (2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy. 
  • 111In oxine labelled mesenchymal stem cell SPECT after intravenous administration in myocardial infarction. 
  • A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats. 
  • A minimally invasive method for creating coronary stenosis in a swine model for MRI and SPECT imaging. 
  • A multicenter, randomized, double-blind study to evaluate the safety, tolerability, and efficacy of OptiMARK (gadoversetamide injection) compared with Magnevist (gadopentetate dimeglumine) in patients with liver pathology: results of a Phase III clinical trial. 
  • A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. 
  • A photolabile ligand for light-activated release of caged copper. 
  • A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation. 
  • A series of new organic-inorganic molybdenum arsenate complexes based on [(ZnO6)(As3O3)2Mo6O18]4- and [HxAs2Mo6O26](6-x)- clusters as SBUs. 
  • Abdominopelvic and lower extremity deep venous thrombosis: evaluation with contrast-enhanced MR venography with a blood-pool agent. 
  • Analysis of quinolizidine alkaloids in Sophora flavescens Ait. by capillary electrophoresis with tris(2,2'-bipyridyl) ruthenium (II)-based electrochemiluminescence detection. 
  • Antibiotic treatment of gastric lymphoma of mucosa-associated lymphoid tissue. An uncontrolled trial. 
  • Application of metal coordination chemistry to explore and manipulate cell biology. 
  • Assessment of photosensitizer dosimetry and tissue damage assay for photodynamic therapy in advanced-stage tumors. 
  • Assessment of whole-brain vasodilatory capacity with acetazolamide challenge at 1.5 T using dynamic contrast imaging with frequency-shifted burst. 
  • Automatic motion correction for breast MR imaging. 
  • Bis(2,2'-bipyridine)(5,6-epoxy-5,6-dihydro-[1,10]phenanthroline)ruthenium: synthesis and electrochemical and electrochemiluminescence characterization. 
  • Blood flow imaging of a posterior circulation stroke. Use of technetium Tc 99m hexamethylpropyleneamine oxime and single photon emission computed tomography. 
  • Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis. 
  • Capillary electrophoresis coupled with electrochemiluminescence detection using porous etched joint. 
  • Capillary electrophoresis with solid-state electrochemiluminescence detector. 
  • Carbohydrate histochemistry of surface epithelium of rat trachea: backscatter and x-ray imaging. 
  • Carbon monoxide releasing molecule-2 enhances α2-antiplasmin activity. 
  • Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart. 
  • Castleman disease of the adrenal gland: MR imaging features. 
  • Cell therapy in murine atherosclerosis: in vivo imaging with high-resolution helical SPECT. 
  • Central neurotoxicity after exposure to organic lead: susceptibility to seizures. 
  • Characterization of Mn(III) complexes of linear and cyclic desferrioxamines as mimics of superoxide dismutase activity. 
  • Characterization of procaine metabolism as probe for the butyrylcholinesterase enzyme investigation by simultaneous determination of procaine and its metabolite using capillary electrophoresis with electrochemiluminescence detection. 
  • Comparison of the effects of hydralazine on tumor and normal tissue blood perfusion by MRI. 
  • Contrast-enhanced MR imaging of neurocutaneous melanosis. 
  • Contrast-enhanced hepatic magnetic resonance angiography at 3 T: does parallel imaging improve image quality? 
  • Control of the orientational order and nonlinear optical response of the "push-pull" chromophore RuPZn via specific incorporation into densely packed monolayer ensembles of an amphiphilic four-helix bundle peptide: characterization of the peptide-chromophore complexes. 
  • Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation. 
  • Crystal structure of bovine Cu,Zn superoxide dismutase at 3 A resolution: chain tracing and metal ligands. 
  • Delayed magnetic resonance hepatic imaging with gadolinium-DTPA. 
  • Demonstration of dural sinus occlusion by the use of MR angiography. 
  • Design of a ruthenium-labeled cytochrome c derivative to study electron transfer with the cytochrome bc1 complex. 
  • Detection of hepatic metastases from colorectal cancer: prospective evaluation of gray scale US versus SonoVue® low mechanical index real time-enhanced US as compared with multidetector-CT or Gd-BOPTA-MRI. 
  • Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery. 
  • Determination of depleted uranium, pyridostigmine bromide and its metabolite in plasma and urine following combined administration in rats. 
  • Determination of sulpiride by capillary electrophoresis with end-column electrogenerated chemiluminescence detection. 
  • Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium. 
  • Direct tris(2,2'-bipyridyl)ruthenium (II) electrochemiluminescence detection of polyamines separated by capillary electrophoresis. 
  • Drug-human serum albumin binding studied by capillary electrophoresis with electrochemiluminescence detection. 
  • Dual contrast perfusion MRI in a single imaging session for assessment of pediatric brain tumors. 
  • Dynamic contrast-enhanced MR imaging assessment of vascularized free fibular grafts. 
  • Dynamic contrast-enhanced MRI and fractal characteristics of percolation clusters in two-dimensional tumor blood perfusion. 
  • Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. 
  • Effect of bismuth salts on systemic and mucosal immune responses to orally administered cholera toxin. 
  • Effect of gadolinium chelate contrast agents on diffusion weighted MR imaging of the liver, spleen, pancreas and kidney at 3 T. 
  • Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model--a pilot study. 
  • Effects of lead exposure on skeletal development in rats. 
  • Effects of water exchange on the measurement of myocardial perfusion using paramagnetic contrast agents. 
  • Electrochemical and electrochemiluminescence study of Ru(bpy)(2+)3-doped silica nanoparticles with covalently grafted biomacromolecules. 
  • Electrochemiluminescence quenching as an indirect method for detection of dopamine and epinephrine with capillary electrophoresis. 
  • Enantioselective cyclization/hydrosilylation of 1,6-enynes catalyzed by a cationic rhodium bis(phosphine) complex. 
  • Enantioselective diene Cyclization/Hydrosilylation catalyzed by optically active palladium bisoxazoline and pyridine-oxazoline complexes. 
  • Enhanced T2 contrast for MR histology of the mouse brain. 
  • Ethyne-bridged (porphinato)zinc(II)-(porphinato)iron(III) complexes: phenomenological dependence of excited-state dynamics upon (porphinato)iron electronic structure. 
  • Evaluation of acute renal failure with magnetic resonance imaging using gradient-echo and Gd-DTPA. 
  • Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection. 
  • Extended organic-inorganic hybrids based on Dawson and double-Dawson-type polyoxometalates. 
  • Extravascular toxicity of two magnetic resonance contrast agents. Preliminary experience in the rat. 
  • Facile and controllable synthesis of polyoxometalate nanorods within polyelectrolyte matrix. 
  • False positive images in the follow-up of patients with brain tumors. 
  • False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors. 
  • Feasibility of laser targeted photo-occlusion of ocular vessels. 
  • Femtosecond pulse train shaping improves two-photon excited fluorescence measurements. 
  • Field-amplified sample stacking capillary electrophoresis with electrochemiluminescence applied to the determination of illicit drugs on banknotes. 
  • Focal nodular hyperplasia: intraindividual comparison of dynamic gadobenate dimeglumine- and ferucarbotran-enhanced magnetic resonance imaging. 
  • Focal nodular hyperplasia: typical and atypical MRI findings with emphasis on the use of contrast media. 
  • Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound. 
  • From chain to network: design and analysis of novel organic-inorganic assemblies from organically functionalized zinc-substituted polyoxovanadates and zinc organoamine subunits. 
  • Gadofosveset-enhanced magnetic resonance angiography of the thoracic vasculature in the equilibrium phase: feasibility and impact of dose. 
  • Gadolinium cardiovascular magnetic resonance predicts reversible myocardial dysfunction and remodeling in patients with heart failure undergoing beta-blocker therapy. 
  • Gadopentetate-dimeglumine-enhanced MR imaging of gliomatosis cerebri: appearance mimicking leptomeningeal tumor dissemination. 
  • Gain in signal-to-noise for first-pass contrast-enhanced abdominal MR angiography at 3 Tesla over standard 1.5 Tesla: prediction with a computer model. 
  • Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children. 
  • Gold(I)-catalyzed intramolecular hydroamination of alkenyl carbamates. 
  • Gold(I)-catalyzed intramolecular hydroamination of unactivated C==C bonds with alkyl ammonium salts. 
  • Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium. 
  • Hepatocellular MR contrast agents: enhancement characteristics of liver parenchyma and portal vein after administration of gadoxetic acid in comparison to gadobenate dimeglumine. 
  • Hepatocellular carcinoma enhancement on contrast-enhanced CT and MR imaging: response assessment after treatment with sorafenib: preliminary results. 
  • Hepatocellular carcinoma in patients with cirrhosis: qualitative comparison of gadobenate dimeglumine-enhanced MR imaging and multiphasic 64-section CT. 
  • Hepatocellular carcinoma lesion characterization: single-institution clinical performance review of multiphase gadolinium-enhanced MR imaging--comparison to prior same-center results after MR systems improvements. 
  • High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli. 
  • Identification of molybdopterin as the organic component of the tungsten cofactor in four enzymes from hyperthermophilic Archaea. 
  • Imaging taxane-induced tumor apoptosis using PEGylated, 111In-labeled annexin V. 
  • In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST. 
  • Inactivation of metabolic enzymes by photo-treatment with zinc meta N-methylpyridylporphyrin. 
  • Incorporation of designed extended chromophores into amphiphilic 4-helix bundle peptides for nonlinear optical biomolecular materials. 
  • Inter- and intra-rater reproducibility of quantitative dynamic contrast enhanced MRI using TWIST perfusion data in a uterine fibroid model. 
  • Interobserver Reproducibility of the PI-RADS Version 2 Lexicon: A Multicenter Study of Six Experienced Prostate Radiologists. 
  • Interobserver Variability Between Breast Imagers Using the Fifth Edition of the BI-RADS MRI Lexicon. 
  • Interrogating conformationally dependent electron-transfer dynamics via ultrafast visible pump/IR probe spectroscopy. 
  • Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone). 
  • Intravenous Gadoxetate Disodium Administration Reduces Breath-holding Capacity in the Hepatic Arterial Phase: A Multi-Center Randomized Placebo-controlled Trial. 
  • Iron chelation properties of an extracellular siderophore exochelin MS. 
  • Irreversible stimulation of adenylate cyclase activity of fat cell membranes of phosphoramidate and phosphonate analogs of GTP. 
  • Isomeric N-alkylpyridylporphyrins and their Zn(II) complexes: inactive as SOD mimics but powerful photosensitizers. 
  • Keys for unlocking photolabile metal-containing cages. 
  • Kinetic study of paracetamol on prolidase activity in erythrocytes by capillary electrophoresis with Ru(bpy)(3) (2+) electrochemiluminescence detection. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • Labeling of peripheral blood polymorphonuclear leukocytes with indium-111: a new method for the quantitation of in-vivo accumulation of PMNLs in rabbit skin. 
  • Lesion detection and assessment of extrahepatic findings in abdominal MRI using hepatocyte specific contrast agents--comparison of Gd-EOB-DTPA and Gd-BOPTA. 
  • Liver metastases: improved detection with dynamic gadolinium-enhanced MR imaging? 
  • MRI detection of myocardial perfusion defects due to coronary artery stenosis with MS-325. 
  • Magnetic resonance imaging in patients with central nervous system pathology: a comparison of OptiMARK (Gd-DTPA-BMEA) and Magnevist (Gd-DTPA). 
  • Magnetic resonance imaging of the pancreas with gadolinium-DTPA. 
  • Magnetic resonance microscopy of mouse embryos. 
  • Mechanism of assembly of the Bis(Molybdopterin guanine dinucleotide)molybdenum cofactor in Rhodobacter sphaeroides dimethyl sulfoxide reductase. 
  • Mechanistic studies of the cycloisomerization of dimethyl diallylmalonate catalyzed by a cationic palladium phenanthroline complex. 
  • Meningioangiomatosis: CT and MR findings. 
  • Metastatic angiosarcoma with thrombocytopenia and intratumoral indium-111-platelet deposition. 
  • Microchip capillary electrophoresis with solid-state electrochemiluminescence detector. 
  • Multiple sclerosis lesions: relationship between MR enhancement pattern and magnetization transfer effect. 
  • Myocardial Damage Detected by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Uncommon in Peripartum Cardiomyopathy. 
  • Myocardial Gd-DTPA kinetics determine MRI contrast enhancement and reflect the extent and severity of myocardial injury after acute reperfused infarction. 
  • Nasal toxicity of manganese sulfate and manganese phosphate in young male rats following subchronic (13-week) inhalation exposure. 
  • Neurotoxic effects of combined treatment of 2,5-hexanedione and triethyllead chloride. 
  • New technique for capillary electrophoresis directly coupled with end-column electrochemiluminescence detection. 
  • Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains. 
  • Nucleophilic addition of organozinc reagents to 2-sulfonyl cyclic ethers: stereoselective synthesis of manassantins A and B. 
  • Optimal characterization of myocardial perfusion with AngioMARK. 
  • PET of hypoxia and perfusion with 62Cu-ATSM and 62Cu-PTSM using a 62Zn/62Cu generator. 
  • PET with 62Cu-ATSM and 62Cu-PTSM is a useful imaging tool for hypoxia and perfusion in pulmonary lesions. 
  • Paramagnetic polymerized liposomes as new recirculating MR contrast agents. 
  • Performance of delayed-enhancement magnetic resonance imaging with gadoversetamide contrast for the detection and assessment of myocardial infarction: an international, multicenter, double-blinded, randomized trial. 
  • Perfusion MRI: the five most frequently asked technical questions. 
  • Phase III clinical evaluation of gadoteridol injection: experience in pediatric neuro-oncologic MR imaging. 
  • Photodynamic modulation of wound healing with BPD-MA and CASP. 
  • Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein. 
  • Preparation of Rh[16aneS4-diol](211)At and Ir[16aneS4-diol](211)At complexes as potential precursors for astatine radiopharmaceuticals. Part I: Synthesis. 
  • Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas. 
  • Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. 
  • Proton-coupled electron transfer. 
  • Quantification of myocardial infarction during coronary occlusion and myocardial salvage after reperfusion using cardiac imaging with technetium-99m hexakis 2-methoxyisobutyl isonitrile. 
  • Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values. 
  • Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution. 
  • Regio- and stereoselective synthesis of alkyl allylic ethers via gold(I)-catalyzed intermolecular hydroalkoxylation of allenes with alcohols. 
  • Relationship of T2-Weighted MRI Myocardial Hyperintensity and the Ischemic Area-At-Risk. 
  • Respiratory motion artifact affecting hepatic arterial phase MR imaging with gadoxetate disodium is more common in patients with a prior episode of arterial phase motion associated with gadoxetate disodium. 
  • Respiratory motion artifact affecting hepatic arterial phase imaging with gadoxetate disodium: examination recovery with a multiple arterial phase acquisition. 
  • Retrospective assessment of the utility of an iron-based agent for contrast-enhanced magnetic resonance venography in patients with endstage renal diseases. 
  • SIB-DOTA: a trifunctional prosthetic group potentially amenable for multi-modal labeling that enhances tumor uptake of internalizing monoclonal antibodies. 
  • SPECT imaging of moyamoya disease using 99mTc-HM-PAO. Comparison with computed tomography findings. 
  • Simultaneous electrochemical and electrochemiluminescence detection for microchip and conventional capillary electrophoresis. 
  • Single breath-hold pulmonary magnetic resonance angiography. Optimization and comparison of three imaging strategies. 
  • Small-molecule dynamics and mechanisms underlying the macroscopic mechanical properties of coordinatively cross-linked polymer networks. 
  • Stability and in vivo behavior of Rh[16aneS4-diol]211 at complex: a potential precursor for astatine radiopharmaceuticals. 
  • Stress cardiac MR imaging compared with stress echocardiography in the early evaluation of patients who present to the emergency department with intermediate-risk chest pain. 
  • Structural and pH dependence of excited state PCET reactions involving reductive quenching of the MLCT excited state of [RuII(bpy)2(bpz)]2+ by hydroquinones. 
  • Structural studies of amphiphilic 4-helix bundle peptides incorporating designed extended chromophores for nonlinear optical biomolecular materials. 
  • Structured Reporting of Magnetic Resonance Enterography for Pediatric Crohn's Disease: Effect on Key Feature Reporting and Subjective Assessment of Disease by Referring Physicians. 
  • Studies on the dissociation of flavin adenine dinucleotide from metalloflavoproteins. 
  • Successful therapy for trilateral retinoblastoma. 
  • Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential. 
  • Syntheses, X-ray crystal structures, and solution behavior of monomeric, cationic, two-coordinate gold(I) pi-alkene complexes. 
  • The Absence of Quadrupolar Nuclei Facilitates Efficient 13 C Hyperpolarization via Reversible Exchange with Parahydrogen. 
  • The effect of nitroglycerin on response to tracheal intubation. Assessment by radionuclide angiography. 
  • The effect of pre- or postnatal lead exposure on Hamilton Search Task in monkeys. 
  • The procoagulant properties of purified fibrinogen concentrate are enhanced by carbon monoxide releasing molecule-2. 
  • The role of dynamic contrast-enhanced magnetic resonance imaging in the diagnosis and management of patients with vascular malformations. 
  • The significance of degenerate processes to enantioselective olefin metathesis reactions promoted by stereogenic-at-Mo complexes. 
  • The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. 
  • Theoretical study of catalytic mechanism for single-site water oxidation process. 
  • Thermodynamic analysis of subunit interactions in Escherichia coli molybdopterin synthase. 
  • Thermodynamics of pyridine coordination in 1,4-phenylene bridged bimetallic (Pd, Pt) complexes containing two N,C,N' motifs, 1,4-M2-[C6(CH2NR2)4-2,3,5,6]. 
  • Three dimensional magnetic resonance microangiography of rat neurovasculature. 
  • Three dimensional magnetic resonance microangiography of rat neurovasculature. 
  • Time-resolved MR angiography as a useful sequence for assessment of ovarian vein reflux. 
  • Uranyl acetate-induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats. 
  • Use of liposomes as carriers for radiation synovectomy. 
  • Variation in toxicity of copper pyrithione among populations and families of the barnacle, Balanus amphitrite. 
  • Venous filling defects on portal venous phase CT of the abdomen and pelvis: clinical implications and positive predictive value for diagnosing deep venous thrombosis. 
  • Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction. 
  • [18F]2-fluoro-2-deoxyglucose-positron emission tomography correlation of gadolinium-enhanced MR imaging of central nervous system neoplasia. 
  • [Ru(bpy)3]2+-doped silica nanoparticles within layer-by-layer biomolecular coatings and their application as a biocompatible electrochemiluminescent tag material. 
  • [Synthesis and anti-influenza virus activities of heteropoly compounds containing rare earth elements]. 
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  Keywords of People

  • Craciunescu, Oana, Associate Professor of Radiation Oncology, Radiation Oncology
  • Fischer, Martin, Associate Research Professor in the Department of Chemistry, Chemistry
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology