Influenza A virus

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  Subject Areas on Research

  • A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor. 
  • A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in Mice. 
  • A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines. 
  • Adherence of bacteria to mammalian cells: inhibition by tunicamycin and streptovirudin. 
  • Alteration in regulation of inflammatory response to influenza a virus and endotoxin in suckling rat pups: a potential relationship to sudden infant death syndrome. 
  • An under-recognized influenza epidemic identified by rapid influenza testing, southern Sri Lanka, 2013. 
  • Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial. 
  • Anti-influenza immune plasma for the treatment of patients with severe influenza A: a randomised, double-blind, phase 3 trial. 
  • Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. 
  • Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. 
  • B cell responses to the 2011/12-influenza vaccine in the aged. 
  • Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid. 
  • Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis. 
  • Comparing influenza and RSV viral and disease dynamics in experimentally infected adults predicts clinical effectiveness of RSV antivirals. 
  • Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate. 
  • DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection. 
  • Delineation of immunologically and biochemically distinct HLA-A2 antigens. 
  • Detection of mucosal antibodies in HIV type 1-infected individuals. 
  • Does exposure to CS gas potentiate the severity of influenza? 
  • Effect of influenza immunization on immunologic and virologic characteristics of pediatric patients infected with human immunodeficiency virus. 
  • Efficient cross-priming of antiviral CD8+ T cells by antigen donor cells is GRP94 independent. 
  • Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication. 
  • Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies. 
  • From high-throughput to therapeutic: host-directed interventions against influenza viruses. 
  • GPER1 is required to protect fetal health from maternal inflammation. 
  • Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. 
  • Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins. 
  • Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis. 
  • Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses. 
  • Heterogeneity of Antiviral Responses in the Upper Respiratory Tract Mediates Differential Non-lytic Clearance of Influenza Viruses. 
  • Impact of a winter respiratory virus season on patients with COPD and association with influenza vaccination. 
  • Implementation of a rapid influenza A/B and RSV direct molecular assay improves emergency department oseltamivir use in paediatric patients. 
  • In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies. 
  • Increased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 Mice. 
  • Influenza A vaccine decreases the incidence of otitis media in 6- to 30-month-old children in day care. 
  • Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity. 
  • Influenza and Antibody-Dependent Cellular Cytotoxicity. 
  • Influenza viruses that require 10 genomic segments as antiviral therapeutics. 
  • Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis. 
  • Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage. 
  • Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance. 
  • Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. 
  • Metabolic and functional impairment of CD8+ T cells from the lungs of influenza-infected obese mice. 
  • Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity. 
  • Obesity-Induced Changes in T-Cell Metabolism Are Associated With Impaired Memory T-Cell Response to Influenza and Are Not Reversed With Weight Loss. 
  • PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection. 
  • Pretreatment of epithelial cells with live Streptococcus pneumoniae has no detectable effect on influenza A virus replication in vitro. 
  • Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir. 
  • Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 
  • Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs. 
  • Requirement of MIP-1 alpha for an inflammatory response to viral infection. 
  • Respiratory syncytial virus and seasonal influenza cause similar illnesses in children with sickle cell disease. 
  • Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome. 
  • Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. 
  • The Influenza B Virus Hemagglutinin Head Domain Is Less Tolerant to Transposon Mutagenesis than That of the Influenza A Virus. 
  • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. 
  • The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines. 
  • The ecology and adaptive evolution of influenza A interspecies transmission. 
  • The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation. 
  • Use of electric cell-substrate impedance sensing as a tool for quantifying cytopathic effect in influenza A virus infected MDCK cells in real-time. 
  • Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules. 
  • Wearable Sensor-Based Detection of Influenza in Presymptomatic and Asymptomatic Individuals. 
  • [Synthesis and anti-influenza virus activities of heteropoly compounds containing rare earth elements]. 
  • alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s). 
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  Keywords of People

  • Clements III, Dennis Alfred, Professor Emeritus of Pediatrics, Pediatrics, General Pediatrics and Adolescent Health