Oryzias

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  Subject Areas on Research

  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces organ- specific differential gene expression in male Japanese medaka (Oryzias latipes). 
  • A high-throughput histoarray for quantitative molecular profiling of multiple, uniformly oriented medaka (Oryzias latipes) embryos. 
  • A purified diet for medaka (Oryzias latipes): refining a fish model for toxicological research. 
  • A simple osmium post-fixation paraffin-embedment technique to identify lipid accumulation in fish liver using medaka (Oryziaslatipes) eggs and eleutheroembryos as lipid rich models. 
  • Adapting the medaka embryo assay to a high-throughput approach for developmental toxicity testing. 
  • Age-dependent in situ hepatic and gill CYP1A activity in the see-through medaka (Oryzias latipes). 
  • An artificial fertilization method with the Japanese medaka: implications in early life stage bioassays and solvent toxicity. 
  • An in vivo look at vertebrate liver architecture: three-dimensional reconstructions from medaka (Oryzias latipes). 
  • Analysis of medaka cytochrome P450 3A homotropic and heterotropic cooperativity. 
  • Anchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka. 
  • Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury. 
  • Biological assessment of bisphenol A degradation in water following direct photolysis and UV advanced oxidation. 
  • Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H2O2 oxidation. 
  • Biomonitoring recycled water in the Santa Ana River Basin in southern California. 
  • Comparisons of polychromatic and monochromatic UV-based treatments of bisphenol-A in water via toxicity assessments. 
  • Cytotoxicity phase of diethylnitrosamine-induced hepatic neoplasia in medaka. 
  • Determining the sensitive developmental stages of intersex induction in medaka (Oryzias latipes) exposed to 17 beta-estradiol or testosterone. 
  • Developmental toxicity and DNA damage from exposure to parking lot runoff retention pond samples in the Japanese medaka (Oryzias latipes). 
  • Diagnostic criteria for degenerative, inflammatory, proliferative nonneoplastic and neoplastic liver lesions in medaka (Oryzias latipes): consensus of a National Toxicology Program Pathology Working Group. 
  • Differential developmental toxicity of naphthoic acid isomers in medaka (Oryzias latipes) embryos. 
  • Dioxinlike properties of a trichloroethylene combustion-generated aerosol. 
  • Does shaking alter the time of hatching in incubated medaka (Oryzias latipes) embryos? 
  • Dynamic gene expression changes precede dioxin-induced liver pathogenesis in medaka fish. 
  • Early life co-exposures to a real-world PAH mixture and hypoxia result in later life and next generation consequences in medaka (Oryzias latipes). 
  • Effects of dietary exposure to the pyrethroid pesticide esfenvalerate on medaka (Oryzias latipes). 
  • Effects of husbandry practices, gender, and normal physiological variation on growth and reproduction of Japanese medaka, Oryzias latipes. 
  • Estrogenic modulation of CYP3A38, CYP3A40, and CYP19 in mature male medaka (Oryzias latipes). 
  • Evaluation of fish models of soluble epoxide hydrolase inhibition. 
  • Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes). 
  • Functional characterization of medaka CYP3A38 and CYP3A40: kinetics and catalysis by expression in a recombinant baculovirus system. 
  • Generation and characterization of neurogenin1-GFP transgenic medaka with potential for rapid developmental neurotoxicity screening. 
  • Identification, characterization, and ontogeny of a second cytochrome P450 3A gene from the fresh water teleost medaka (Oryzias latipes). 
  • Immunohistochemical characterization of the hepatic progenitor cell compartment in medaka (Oryzias latipes) following hepatic injury. 
  • Increasing uptake and bioactivation with development positively modulate diazinon toxicity in early life stage medaka (Oryzias latipes). 
  • Influence of water hardening of the chorion on cadmium accumulation in medaka (Oryzias latipes) eggs. 
  • Maternal dietary exposure to selenium nanoparticle led to malformation in offspring. 
  • Metabolic changes in Japanese medaka (Oryzias latipes) during embryogenesis and hypoxia as determined by in vivo 31P NMR. 
  • Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka. 
  • Organophosphate-induced acetylcholinesterase inhibition and embryonic retinal cell necrosis in vivo in the teleost (Oryzias latipes). 
  • Paralogous vitamin D receptors in teleosts: transition of nuclear receptor function. 
  • Parental dietary seleno-L-methionine exposure and resultant offspring developmental toxicity. 
  • Phenotypic characterization of transgenic Japanese medaka (Oryzias latipes) that express a red fluorescent protein in hepatocytes. 
  • Progression of hepatic neoplasia in medaka (Oryzias latipes) exposed to diethylnitrosamine. 
  • Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka. 
  • Quantifiable biomarkers of normal aging in the Japanese medaka fish (Oryzias latipes). 
  • Silver nanocolloids disrupt medaka embryogenesis through vital gene expressions. 
  • Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation. 
  • Silver toxicity across salinity gradients: the role of dissolved silver chloride species (AgCl x ) in Atlantic killifish (Fundulus heteroclitus) and medaka (Oryzias latipes) early life-stage toxicity. 
  • Stage sensitivity of medaka (Oryzias latipes) eggs and embryos to permethrin. 
  • Stage-dependent differences in effects of carbaryl on population growth rate in Japanese medaka (Oryzias latipes). 
  • Stage-specific toxicity of cypermethrin to medaka (Oryzias latipes) eggs and embryos using a refined methodology for an in vitro fertilization bioassay. 
  • TCDD disrupts hypural skeletogenesis during medaka embryonic development. 
  • The effects of model polysiloxane and fouling-release coatings on embryonic development of a sea urchin (Arbacia punctulata) and a fish (Oryzias latipes). 
  • Three periods of regulatory innovation during vertebrate evolution. 
  • Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics. 
  • Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro. 
  • Ultrastructural alterations in liver of medaka (Oryzias latipes) exposed to diethylnitrosamine. 
  • Uptake of silver nanoparticles and toxicity to early life stages of Japanese medaka (Oryzias latipes): effect of coating materials. 
  • Use of medaka in toxicity testing. 
  • Utilizing in vivo nuclear magnetic resonance spectroscopy to study sublethal stress in aquatic organisms. 
  • Variations of light and temperature regimes and resulting effects on reproductive parameters in medaka (Oryzias latipes). 
  • Vulnerable windows for developmental ethanol toxicity in the Japanese medaka fish (Oryzias latipes). 
  • ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish.