Osteoarthritis

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  Subject Areas on Research

  • A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear. 
  • A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis. 
  • A discrete-choice experiment of United Kingdom patients' willingness to risk adverse events for improved function and pain control in osteoarthritis. 
  • A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis. 
  • A flexible statistical model for alignment of label-free proteomics data--incorporating ion mobility and product ion information. 
  • A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene. 
  • A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis. 
  • A medical education. 
  • A mutation in cartilage oligomeric matrix protein (COMP) causes early-onset osteoarthritis in a large kindred study. 
  • A new approach for assessing early osteoarthritis in the rat. 
  • A novel quantitative approach for evaluating contact mechanics of meniscal replacements. 
  • A paper by Jones et al. Alterations in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage (Journal of Biomechanics 32, 1999, 119-127) 
  • A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials. 
  • A systematic review of recommendations and guidelines for the management of osteoarthritis: The chronic osteoarthritis management initiative of the U.S. bone and joint initiative. 
  • Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. 
  • Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. 
  • Alterations in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage. 
  • Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration. 
  • Altered trabecular bone structure and delayed cartilage degeneration in the knees of collagen VI null mice. 
  • Amino Acid Profile of Synovial Fluid Following Intra-articular Ankle Fracture. 
  • Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing. 
  • Ankle alignment on lateral radiographs. Part 2: reliability and validity of measures. 
  • Ankle arthrodesis after failed total ankle replacement: a systematic review of the literature. 
  • Ankle arthroscopy: outcome in 79 consecutive patients. 
  • Anterior interosseus nerve injury following elbow arthroscopy. 
  • Aplastic anaemia associated with fenbufen: a report of two cases. 
  • Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis. 
  • Applied biomechanics in articular injuries: perspectives in the basic investigation of articular injuries and clinical application. 
  • Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines. 
  • Articular hypermobility is a protective factor for hand osteoarthritis. 
  • Assessment of hand osteoarthritis: correlation between thermographic and radiographic methods. 
  • Assessment of the utility of biomarkers of osteoarthritis in the guinea pig. 
  • Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study. 
  • Association between serum and urine biomarkers and lumbar spine individual radiographic features: the Johnston County Osteoarthritis Project. 
  • Associations between biomarkers of joint metabolism, hand osteoarthritis, and hand pain and function: the Johnston County Osteoarthritis Project. 
  • Associations of coping strategies with diary based pain variables among Caucasian and African American patients with osteoarthritis. 
  • Atlas of radiographic features of osteoarthritis of the ankle and hindfoot. 
  • Autologous bone from hip or knee replacement in simultaneous foot or ankle arthrodeses. 
  • Automated Internet-based pain coping skills training to manage osteoarthritis pain: a randomized controlled trial. 
  • Autoregulation of Tcr V region epitopes in autoimmune disease. 
  • Back pain in the elderly: updated diagnosis and management. 
  • Basic methods in histopathology of joint tissues. 
  • Bilateral silicone induced synovitis of the wrist. 
  • Biomarkers and proteomic analysis of osteoarthritis. 
  • Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study. 
  • Biomarkers for equine joint injury and osteoarthritis. 
  • Biomarkers for osteoarthritis: current position and steps towards further validation. 
  • Biomarkers in osteoarthritis. 
  • Biomechanical Comparison of Suture-Button Suspensionplasty and LRTI for Basilar Thumb Arthritis. 
  • Biomechanical factors in osteoarthritis. 
  • Bipolar arthroplasty for recurrent total hip instability. 
  • Brief report: differences in multijoint symptomatic osteoarthritis phenotypes by race and sex: the Johnston County Osteoarthritis Project. 
  • Calcaneocuboid joint subluxation after calcaneal lengthening for planovalgus foot deformity in children with cerebral palsy. 
  • Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use. 
  • Cardiovascular Disease Prevalence in Patients with Osteoarthritis, Gout, or Both. 
  • Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method. 
  • Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. 
  • Central pain contributions in osteoarthritis: next steps for improving recognition and treatment? 
  • Challenges and controversies of complex interventions in osteoarthritis management: recognizing inappropriate and discordant care. 
  • Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. 
  • Chondral delamination of the knee in soccer players. 
  • Chondroprotective effects of a polycarbonate-urethane meniscal implant: histopathological results in a sheep model. 
  • Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. 
  • Classification of osteoarthritis biomarkers: a proposed approach. 
  • Clinical algorithms to aid osteoarthritis guideline dissemination. 
  • Clinician's comment on the management of pain in arthritis. 
  • Closing the gap between bench and bedside research for early arthritis therapies (EARTH): report from the AOSSM/NIH U-13 Post-Joint Injury Osteoarthritis Conference II. 
  • Cognitive behavioral control of arthritis pain. 
  • Cognitive behavioral therapy for chronic pain is effective, but for whom? 
  • Cognitive-behavioral treatment for comorbid insomnia and osteoarthritis pain in primary care: the lifestyles randomized controlled trial. 
  • Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis. 
  • Community-based aquatic exercise and quality of life in persons with osteoarthritis. 
  • Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis. 
  • Comparison of pain measures among patients with osteoarthritis. 
  • Comparison of three comorbidity measures for predicting health service use in patients with osteoarthritis. 
  • Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project. 
  • Computed Tomographic Evaluation of Joint Geometry in Patients With End-Stage Ankle Osteoarthritis. 
  • Conversion of Tibiotalar Arthrodesis to Total Ankle Arthroplasty. 
  • Coronal plane ankle alignment, gait, and end-stage ankle osteoarthritis. 
  • Correction of post-traumatic flexion contracture of the elbow by anterior capsulotomy. 
  • Cost effectiveness analysis of hemiarthroplasty and total shoulder arthroplasty. 
  • Cost offsets to medicare attributable to receipt of hip, knee, and shoulder arthroplasty. 
  • Cost-effectiveness Analysis of Hip Arthroscopic Surgery and Structured Rehabilitation Alone in Individuals With Hip Labral Tears: Letter to the Editor. 
  • Cost-effectiveness of increased telephone contact for patients with osteoarthritis. A randomized, controlled trial. 
  • Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. 
  • Daily pain variations among patients with hand, hip, and knee osteoarthritis. 
  • Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. 
  • Defining the Burden of Osteoarthritis in Population-Based Surveys. 
  • Degenerative lumbar stenosis: the neurosurgical perspective. 
  • Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration. 
  • Development and Evaluation of the Boston University Osteoarthritis Functional Pain Short Form (BU-OA-FPS). 
  • Developmental and osteoarthritic changes in Col6a1-knockout mice: biomechanics of type VI collagen in the cartilage pericellular matrix. 
  • Diagnosis of osteoarthritis in relation to molecular processes in cartilage: comment on the article by Clark et al. 
  • Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: recommendations of the International RDC/TMD Consortium Network* and Orofacial Pain Special Interest Group†. 
  • Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury. 
  • Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: the Johnston County Osteoarthritis project. 
  • Differences in osteoarthritis self-management support intervention outcomes according to race and health literacy. 
  • Differences in the Lateral Compartment Joint Space Width After Anterior Cruciate Ligament Reconstruction: Data From the MOON Onsite Cohort. 
  • Directing clinical care using lower extremity biomechanics in patients with ankle osteoarthritis and ankle arthroplasty. 
  • Do biochemical markers have a role in osteoarthritis diagnosis and treatment? 
  • Does lipopolysaccharide-mediated inflammation have a role in OA? 
  • Does radiographic osteoarthritis correlate with flexibility of the lumbar spine? 
  • Editorial: Insulin Resistance: Releasing the Brakes on Synovial Inflammation and Osteoarthritis? 
  • Effect of end-stage hip, knee, and ankle osteoarthritis on walking mechanics. 
  • Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes. 
  • Elucidating the Molecular Composition of Cartilage by Proteomics. 
  • Emerging ideas: prevention of posttraumatic arthritis through interleukin-1 and tumor necrosis factor-alpha inhibition. 
  • Emerging roles for long noncoding RNAs in skeletal biology and disease. 
  • Epidemiology of Fracture Nonunion in 18 Human Bones. 
  • Epidemiology of ankle arthritis: report of a consecutive series of 639 patients from a tertiary orthopaedic center. 
  • Erythrocyte sedimentation rate and C-reactive protein levels are poorly correlated with clinical measures of disease activity in rheumatoid arthritis, systemic lupus erythematosus and osteoarthritis patients. 
  • Establishment of reference intervals for osteoarthritis-related soluble biomarkers: the FNIH/OARSI OA Biomarkers Consortium. 
  • Evaluating intra-articular drug delivery for the treatment of osteoarthritis in a rat model. 
  • Everyday life with osteoarthritis or rheumatoid arthritis: independent effects of disease and gender on daily pain, mood, and coping. 
  • Expression of matrix metalloproteinase 1 in rodents: comment on the article by Huebner et al. 
  • Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. 
  • Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis. 
  • Factors related to hip muscle weakness following fixation of acetabular fractures. 
  • Feasibility of a dyadic intervention for management of osteoarthritis: a pilot study with older patients and their spousal caregivers. 
  • First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis. 
  • For the patient. Do patients use prescribed medicine for osteoarthritis? 
  • Functional decline in older adults. 
  • Gaps in appropriate use of treatment strategies in osteoarthritis. 
  • Gender and limb differences in temporal gait parameters and gait variability in ankle osteoarthritis. 
  • Gender differences in NSAID use among older adults with osteoarthritis. 
  • Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. 
  • Genetics of osteoarthritis. 
  • Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family. 
  • Global metabolic profiling of human osteoarthritic synovium. 
  • Group interventions for co-morbid insomnia and osteoarthritis pain in primary care: the lifestyles cluster randomized trial design. 
  • Health-related quality of life after hip arthroplasty with and without an extended-duration continuous posterior lumbar plexus nerve block: a prospective, 1-year follow-up of a randomized, triple-masked, placebo-controlled study. 
  • Health-related quality of life among older adults with arthritis. 
  • Health-related quality of life and health service use among older adults with osteoarthritis. 
  • Heberden's nodes. 
  • Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis. 
  • High Survivorship and Few Complications With Cementless Total Wrist Arthroplasty at a Mean Followup of 9 Years. 
  • High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment. 
  • High-resolution imaging of progressive articular cartilage degeneration. 
  • Histopathology atlas of animal model systems - overview of guiding principles. 
  • Hop tests correlate with IKDC and KOOS at minimum of 2 years after primary ACL reconstruction. 
  • How direct-to-consumer television advertising for osteoarthritis drugs affects physicians' prescribing behavior. 
  • How do physicians weigh benefits and risks associated with treatments in patients with osteoarthritis in the United Kingdom? 
  • Iatrogenic Arteriovenous Fistula With Associated Pseudoaneurysm of Posterior Tibial Artery After Revision Total Ankle Arthroplasty: A Case Report. 
  • Identification of an urinary metabolite profile associated with osteoarthritis. 
  • Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs. 
  • Imaging biomarker validation and qualification report: sixth OARSI Workshop on Imaging in Osteoarthritis combined with third OA Biomarkers Workshop. 
  • Immigration check for neutrophils in RA lining: laminin alpha5 low expression regions act as exit points. 
  • Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. 
  • Impact of Diabetes on Outcome of Total Ankle Replacement. 
  • Impact of direct-to-consumer predictive genomic testing on risk perception and worry among patients receiving routine care in a preventive health clinic. 
  • Impact of disease severity and gastrointestinal side effects on the health state preferences of patients with osteoarthritis. 
  • Impact of osteoarthritis on sports careers. 
  • In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. 
  • Inflammation (or synovitis)-driven osteoarthritis: an opportunity for personalizing prognosis and treatment? 
  • Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture. 
  • Inflammatory Microenvironment Persists After Bone Healing in Intra-articular Ankle Fractures. 
  • Inflammatory cytokines and cellular metabolites as synovial fluid biomarkers of posttraumatic ankle arthritis. 
  • Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage. 
  • Integrative repair of the meniscus: lessons from in vitro studies. 
  • Interleukin-1 inhibits osmotically induced calcium signaling and volume regulation in articular chondrocytes. 
  • Intermediate-term follow-up after ankle distraction for treatment of end-stage osteoarthritis. 
  • Interpretation of serum C-reactive protein (CRP) levels for cardiovascular disease risk is complicated by race, pulmonary disease, body mass index, gender, and osteoarthritis. 
  • Is there any value to arthroscopic debridement of ankle osteoarthritis and impingement? 
  • J. Leonard Goldner Award 2011: changes in pain, function, and gait mechanics two years following total ankle arthroplasty performed with two modern fixed-bearing prostheses. 
  • Joint hypermobility is not positively associated with prevalent multiple joint osteoarthritis: a cross-sectional study of older adults. 
  • Joint-specific hand symptoms and self-reported and performance-based functional status in African Americans and Caucasians: The Johnston County Osteoarthritis Project. 
  • Kinetics of iron deposition in rheumatoid joints. 
  • Laboratory pain perception and clinical pain in post-menopausal women and age-matched men with osteoarthritis: relationship to pain coping and hormonal status. 
  • Life-long caloric restriction does not alter the severity of age-related osteoarthritis. 
  • Lifetime Risk of Symptomatic Hand Osteoarthritis: The Johnston County Osteoarthritis Project. 
  • Liposomal Bupivacaine Versus Continuous Popliteal Sciatic Nerve Block in Total Ankle Arthroplasty. 
  • Long-Term Mortality Trends After Total Hip and Knee Arthroplasties: A Population-Based Study. 
  • Long-term results after Russe bone-grafting: the effect of malunion of the scaphoid. 
  • Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis. 
  • Low accuracy of interpretation of rotator cuff MRI in patients with osteoarthritis. 
  • Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis. 
  • Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis. 
  • Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis. 
  • Mechanical sensation and pain thresholds in patients with chronic arthropathies. 
  • Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin. 
  • Membrane attack complex of complement in rheumatoid synovial tissue demonstrated by immunofluorescent microscopy. 
  • Meniscectomy in osteoarthritis. 
  • Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. 
  • Midterm Results of the Salto Talaris Total Ankle Arthroplasty. 
  • Modulating hedgehog signaling can attenuate the severity of osteoarthritis. 
  • Molecular abnormalities of human plasminogen isolated from synovial fluid of rheumatoid arthritis patients. 
  • Motion versus fixed distraction of the joint in the treatment of ankle osteoarthritis: a prospective randomized controlled trial. 
  • Notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance. 
  • Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice. 
  • Nurse practitioners can effectively deliver pain coping skills training to osteoarthritis patients with chronic pain: A randomized, controlled trial. 
  • OARSI Clinical Trials Recommendations: Design and conduct of clinical trials for hand osteoarthritis. 
  • OARSI Clinical Trials Recommendations: Design and conduct of clinical trials of lifestyle diet and exercise interventions for osteoarthritis. 
  • OARSI Clinical Trials Recommendations: Design and conduct of implementation trials of interventions for osteoarthritis. 
  • OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis. 
  • Older spouses' perceptions of partners' chronic arthritis pain: implications for spousal responses, support provision, and caregiving experiences. 
  • Operative Wound Complications Following Total Ankle Arthroplasty. 
  • Orthopaedic surgeon workforce and volume assessment for total hip and knee replacement in the United States: preparing for an epidemic. 
  • Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells. 
  • Osteoarthritic knee pain: a behavioral analysis. 
  • Osteoarthritis and sleep: the Johnston County Osteoarthritis Project. 
  • Osteoarthritis and the impact on quality of life health indicators. 
  • Osteoarthritis as a disease of the cartilage pericellular matrix. 
  • Osteoarthritis in physical medicine and rehabilitation. 
  • Osteoarthritis of the sternoclavicular joint. Radiographic features and pathologic correlation. 
  • Osteoarthritis year 2010 in review: biochemical markers. 
  • Osteoarthritis--a case for personalized health care? 
  • Osteoarthritis: From Palliation to Prevention: AOA Critical Issues. 
  • Osteoarthritis: Models for appropriate care across the disease continuum. 
  • Osteoarthritis: The zinc link. 
  • Other surgical techniques for osteoarthritis. 
  • Outcomes of Ankle Distraction for the Treatment of Ankle Arthritis. 
  • Outcomes with daptomycin versus standard therapy for osteoarticular infections associated with Staphylococcus aureus bacteraemia. 
  • Oxaprozin and piroxicam, nonsteroidal antiinflammatory drugs with long half-lives: effect of protein-binding differences on steady-state pharmacokinetics. 
  • Oxygen, nitric oxide and articular cartilage. 
  • Pain coping skills training for African Americans with osteoarthritis study: baseline participant characteristics and comparison to prior studies. 
  • Pain coping strategies in osteoarthritis patients. 
  • Pain coping strategies that predict patients' and spouses' ratings of patients' self-efficacy. 
  • Pain in the rheumatic diseases. Practical aspects of diagnosis and treatment. 
  • Pain management in rheumatology research, training, and practice. 
  • Pain measurement in elders with chronic low back pain: traditional and alternative approaches. 
  • Participant evaluation of a telephone-based osteoarthritis self-management program, 2006-2009. 
  • Pathogenesis and treatment of osteoarthritis. 
  • Pathogenesis of Posttraumatic Osteoarthritis of the Ankle. 
  • Patient Risk Factors Do Not Impact 90-Day Readmission and Emergency Department Visitation After Total Ankle Arthroplasty: Implications for the Comprehensive Care for Joint Replacement (CJR) Bundled Payment Plan. 
  • Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis. 
  • Patient-Reported Outcomes, Function, and Gait Mechanics After Fixed and Mobile-Bearing Total Ankle Replacement. 
  • Patterns of opioid analgesic prescription among patients with osteoarthritis. 
  • Performance of global assessments of hip, knee, and back symptom change. 
  • Periarticular osteotomies: the importance of limb alignment. 
  • Physical Activity Predicts Higher Physical Function in Older Adults: The Osteoarthritis Initiative. 
  • Physician Beliefs about Physical and Mental Competency of Patients Applying for Concealed Weapon Permits. 
  • Pilot study of pain and coping among patients with osteoarthritis: a daily diary analysis. 
  • Plantar pressure distribution after tibiotalar arthrodesis. 
  • Plenary session on aging and biology: effects on growth and plasticity through the lifespan. Physical Disabilities through the Lifespan Conference. 
  • Polyethylene Fracture Following STAR Ankle Arthroplasty: A Report of Three Cases. 
  • Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention. 
  • Postoperative complications of posterior ankle and hindfoot arthroscopy. 
  • Posttraumatic osteoarthritis. 
  • Predicting normal glenoid version from the pathologic scapula: a comparison of 4 methods in 2- and 3-dimensional models. 
  • Prioritization of patient-centered comparative effectiveness research for osteoarthritis. 
  • Pseudoaneurysm after shoulder arthroscopy. 
  • Psychological approaches to understanding and treating arthritis pain. 
  • Psychometric Evaluation of the Patient's Knee Implant Performance Questionnaire. 
  • Psychosocial factors and the pain experience of osteoarthritis patients: new findings and new directions. 
  • Quantification of condylar resorption in temporomandibular joint osteoarthritis. 
  • Quantification of keratan sulfate in blood as a marker of cartilage catabolism. 
  • Quantification of the whole-body burden of radiographic osteoarthritis using factor analysis. 
  • RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance. 
  • Race and sex differences in willingness to undergo total joint replacement: the Johnston County Osteoarthritis Project. 
  • Racial and ethnic differences in osteoarthritis: prevalence, outcomes, and medical care. 
  • Racial and ethnic disparities in osteoarthritis phenotypes. 
  • Racial differences in analgesic/anti-inflammatory medication adherence among patients with osteoarthritis. 
  • Racial differences in health care utilization among patients with osteoarthritis. 
  • Racial differences in sleep medication use: a cross-sectional study of the Johnston County Osteoarthritis Project. 
  • Racial variations in self-reported osteoarthritis symptom severity among veterans. 
  • Racial/ethnic variations in non-steroidal anti-inflammatory drug (NSAID) use among patients with osteoarthritis. 
  • Radiographic features of hand osteoarthritis in adult Kashin-Beck Disease (KBD): the Yongshou KBD study. 
  • Ratio of Range of Motion of the Ankle and Surrounding Joints After Total Ankle Replacement: A Radiographic Cohort Study. 
  • Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. 
  • Recent advances and future directions in the biopsychosocial assessment and treatment of arthritis. 
  • Recommendations of the OARSI FDA Osteoarthritis Devices Working Group. 
  • Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage. 
  • Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis. 
  • Relationship of limb length inequality with radiographic knee and hip osteoarthritis. 
  • Relationship of radiographic and clinical variables to pinch and grip strength among individuals with osteoarthritis. 
  • Replacement of intervertebral discs in chimpanzees by silicone-dacron implants: a preliminary report. 
  • Reply to "Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?" by Wei et al. 
  • Risk Factors and Predictors of Subsequent ACL Injury in Either Knee After ACL Reconstruction: Prospective Analysis of 2488 Primary ACL Reconstructions From the MOON Cohort. 
  • Rusty hinges. Understanding osteoarthritis pain. 
  • Self-efficacy for arthritis pain: relationship to perception of thermal laboratory pain stimuli. 
  • Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden. 
  • Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair. 
  • Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project. 
  • Short and Long-Term Postoperative Complications Following Total Joint Arthroplasty in Patients With Human Immunodeficiency Virus, Hepatitis B, or Hepatitis C. 
  • Short-term improvement in insomnia symptoms predicts long-term improvements in sleep, pain, and fatigue in older adults with comorbid osteoarthritis and insomnia. 
  • Simultaneous and staged bilateral total knee arthroplasty. 
  • Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy. 
  • Soluble recombinant neutral endopeptidase (CD10) as a potential antiinflammatory agent. 
  • Spouse-assisted coping skills training in the management of osteoarthritic knee pain. 
  • State of the evidence. 
  • Stem cell-based therapies for osteoarthritis: challenges and opportunities. 
  • Subchondral bone remodeling is related to clinical improvement after joint distraction in the treatment of ankle osteoarthritis. 
  • Subgroups of older adults with osteoarthritis based upon differing comorbid symptom presentations and potential underlying pain mechanisms. 
  • Summary of the OA biomarkers workshop 2009--biochemical biomarkers: biology, validation, and clinical studies. 
  • Summary of the OA biomarkers workshop 2010 - genetics and genomics: new targets in OA. 
  • Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus. 
  • Surgeon training and complications in total ankle arthroplasty. 
  • Surgical treatment of the arthritic varus ankle. 
  • Symptoms of the knee and hip in individuals with and without limb length inequality. 
  • Synovial Fluid Profile at the Time of Anterior Cruciate Ligament Reconstruction and Its Association With Cartilage Matrix Composition 3 Years After Surgery. 
  • Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro. 
  • Synovial mononuclear phagocytes in rheumatoid arthritis and osteoarthritis: quantitative and functional aspects. 
  • Targets to tackle--the pathophysiology of the disease. 
  • Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. 
  • The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. 
  • The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig. 
  • The Self-Management of OsteoArthritis in Veterans (SeMOA) Study: design and methodology. 
  • The Value of Motion: Patient-Reported Outcome Measures Are Correlated With Range of Motion in Total Ankle Replacement. 
  • The anterior cruciate ligament and arthritis. 
  • The clinical experience with silicone-dacron metacarpophalangeal and interphalangeal joint prostheses. 
  • The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments? 
  • The effect of tibiotalar alignment on coronal plane mechanics following total ankle replacement. 
  • The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction. 
  • The efficacy of cryotherapy following arthroscopic knee surgery. 
  • The efficacy, tolerability, and safety of 1200 mg/d of oxaprozin and 1500 mg/d of nabumetone in the treatment of patients with osteoarthritis of the knee. 
  • The failed total ankle. 
  • The high failure rate of biologic resurfacing of the glenoid in young patients with glenohumeral arthritis. 
  • The influence of concomitant triceps surae lengthening at the time of total ankle arthroplasty on postoperative outcomes. 
  • The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants. 
  • The mechanobiology of articular cartilage: bearing the burden of osteoarthritis. 
  • The relationship between pain and eating among overweight and obese individuals with osteoarthritis: an ecological momentary study. 
  • The role of biomechanics and inflammation in cartilage injury and repair. 
  • The role of innate immunity in osteoarthritis: when our first line of defense goes on the offensive. 
  • The role of mechanical loading in the onset and progression of osteoarthritis. 
  • The role of metabolomics in osteoarthritis research. 
  • The structure and function of the pericellular matrix of articular cartilage. 
  • The symptoms of osteoarthritis and the genesis of pain. 
  • The symptoms of osteoarthritis and the genesis of pain. 
  • The use of the Artelon CMC Spacer for osteoarthritis of the basal joint of the thumb. 
  • The value of measuring variability in osteoarthritis pain. 
  • The value of serial postoperative radiographs of total knee arthroplasties. 
  • Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture. 
  • Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages. 
  • Tibiotalocalcaneal Arthrodesis Using a Nitinol Intramedullary Hindfoot Nail. 
  • Time-Dependent Effects on Synovial Fluid Composition During the Acute Phase of Human Intra-articular Ankle Fracture. 
  • Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. 
  • Total knee arthroplasty following high tibial osteotomy for osteoarthritis. 
  • Treatment expectation for pain coping skills training: relationship to osteoarthritis patients' baseline psychosocial characteristics. 
  • Type II collagen markers in osteoarthritis: what do they indicate? 
  • Ulnohumeral arthroplasty. 
  • Understanding the adoption of arthritis self-management: stages of change profiles among arthritis patients. 
  • Unipedal balance is affected by lower extremity joint arthroplasty procedure 1 year following surgery. 
  • Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. 
  • Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening. 
  • Use of non-pharmacological therapies among patients with osteoarthritis. 
  • Validity and factor structure of the AUSCAN Osteoarthritis Hand Index in a community-based sample. 
  • Validity, factor structure, and clinical relevance of the AUSCAN Osteoarthritis Hand Index. 
  • Value of biomarkers in osteoarthritis: current status and perspectives. 
  • Variation in osteoarthritis biomarkers from activity not food consumption. 
  • Viscoelastic properties of chondrocytes from normal and osteoarthritic human cartilage. 
  • Waiting for action on the osteoarthritis front. 
  • Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and white men and women: the Johnston County Osteoarthritis Project. 
  • Why is obesity associated with osteoarthritis? Insights from mouse models of obesity. 
  • Widespread somatosensory sensitivity in naturally occurring canine model of osteoarthritis. 
  • Will we be able to repair osteoarthritic joints? New drugs and surgical techniques for cartilage problems. 
  • alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation. 
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  Keywords of People

  • Allen, Kelli Dominick, Adjunct Professor in the Department of Medicine, Medicine, General Internal Medicine
  • Attarian, David Edward, Professor of Orthopaedic Surgery, Orthopaedics
  • Grambow, Steven C., Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology
  • McConnell, Eleanor Schildwachter, Associate Professor in the School of Nursing, with tenure, School of Nursing
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Olson, Steven Arthur, Professor of Orthopaedic Surgery, Orthopaedics
  • Orlando, Lori Ann, Associate Professor of Medicine, Medicine, General Internal Medicine
  • Reed, Shelby Derene, Professor in Population Health Sciences, Duke Science & Society
  • Zullig, Leah L, Associate Professor in Population Health Sciences, Medicine, General Internal Medicine