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Subject Areas on Research
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'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass?
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APPOSITIONAL BONE FORMATION IN CANINE BONE: A QUANTITATIVE MICROSCOPIC STUDY USING TETRACYCLINE MARKERS.
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Aluminum deposition at the osteoid-bone interface. An epiphenomenon of the osteomalacic state in vitamin D-deficient dogs.
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An injectable method for noninvasive spine fusion.
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Are recombinant human bone morphogenetic protein-7 and tobramycin compatible? An experiment in rats.
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Association between blood lead and the risk of amyotrophic lateral sclerosis.
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BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation.
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BMP-2 inhibits tumor-initiating ability in human renal cancer stem cells and induces bone formation.
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Biological basis of bone formation, remodeling, and repair-part III: biomechanical forces.
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Biomineralized matrices dominate soluble cues to direct osteogenic differentiation of human mesenchymal stem cells through adenosine signaling.
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Biphasic effects of interleukin-1beta on osteoblast differentiation in vitro.
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Blockade of angiotensin II type 2 receptor by PD123319 inhibits osteogenic differentiation of human mesenchymal stem cells via inhibition of extracellular signal-regulated kinase signaling.
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Blood vessels engineered from human cells.
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Bone Marrow Stress Decreases Osteogenic Progenitors.
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Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression.
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Bone formation induced by BMP-2 in human osteosarcoma cells.
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Bone protection by inhibition of microRNA-182.
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Bone-associated gene evolution and the origin of flight in birds.
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CDDO-Me, Sulforaphane and tBHQ attenuate the RANKL-induced osteoclast differentiation via activating the NRF2-mediated antioxidant response.
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Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling.
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Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development.
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Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development.
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Cell-based gene therapy for repair of critical size defects in the rat fibula.
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Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.
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Characterization of adipose-derived mesenchymal stem cell combinations for vascularized bone engineering.
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Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.
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Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model.
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Comparative rates of development in Monodelphis and Didelphis.
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Comparative studies of prosthetic materials in the left atrium of the dog.
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Comparison of guided bone formation from periosteum and muscle fascia.
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Congenital abnormalities of the thoracic and lumbar spine.
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Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells.
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Cranial osteogenesis in Monodelphis domestica (Didelphidae) and Macropus eugenii (Macropodidae).
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Debridement, Curettage, and Bone Marrow Stimulation: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle.
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Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA.
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Do Surface Porosity and Pore Size Influence Mechanical Properties and Cellular Response to PEEK?
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Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss.
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EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira syndrome.
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Effect of age on biomaterial-mediated in situ bone tissue regeneration.
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Effect of porous orthopaedic implant material and structure on load sharing with simulated bone ingrowth: A finite element analysis comparing titanium and PEEK.
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Effect of scaffold microarchitecture on osteogenic differentiation of human mesenchymal stem cells.
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Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells.
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Enhanced osteogenic activity of poly(ester urea) scaffolds using facile post-3D printing peptide functionalization strategies.
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Enhanced osteogenic potential of mesenchymal stem cells from cortical bone: a comparative analysis.
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Evaluation of pectus bar position and osseous bone formation.
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Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development.
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Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin.
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Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.
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Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds.
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Genetic engineering of mesenchymal stem cells and its application in human disease therapy.
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Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation.
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Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4.
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High-content imaging-based screening of microenvironment-induced changes to stem cells.
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In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing.
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In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts.
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In vivo comparison of biomineralized scaffold-directed osteogenic differentiation of human embryonic and mesenchymal stem cells.
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Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevents estrogen deficiency-induced bone loss.
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Inducible regulation of Runx2-stimulated osteogenesis.
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Influence of discrete and continuous culture conditions on human mesenchymal stem cell lineage choice in RGD concentration gradient hydrogels.
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Influence of lead on mineralization during bone growth.
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Investigating the Osteoinductive Potential of a Decellularized Xenograft Bone Substitute.
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Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca.
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Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro.
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Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.
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Macrophages Promote Aortic Valve Cell Calcification and Alter STAT3 Splicing.
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Metatarsal lengthening by distraction osteogenesis: a report of two cases.
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Mice lacking Bmp6 function.
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Mineralized Biomaterials Mediated Repair of Bone Defects Through Endogenous Cells.
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Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells.
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Mineralized synthetic matrices as an instructive microenvironment for osteogenic differentiation of human mesenchymal stem cells.
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Morphogenesis in sea urchin embryos: linking cellular events to gene regulatory network states.
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Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of mesenchymal stem cells.
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Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia.
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Ovine model for engineering bone segments.
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PTH receptor signaling in osteoblasts regulates endochondral vascularization in maintenance of postnatal growth plate.
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Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model.
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Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia.
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Periosteum-guided prefabrication of vascularized bone of clinical shape and volume.
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Pharmacologic targeting of β-catenin improves fracture healing in old mice.
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Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery.
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Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating on PEEK.
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Progenitor cell mobilization enhances bone healing by means of improved neovascularization and osteogenesis.
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Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis.
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Role of mitogen-activated protein kinase in osteoblast differentiation.
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Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype.
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Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro.
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Scaffold-based rhBMP-2 therapy in a rat alveolar defect model: implications for human gingivoperiosteoplasty.
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Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair.
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Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts.
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Specification of chondrocytes and cartilage tissues from embryonic stem cells.
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Stem cell differentiation indicated by noninvasive photonic characterization and fractal analysis of subcellular architecture.
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Stereoselective synthesis and osteogenic activity of subglutinols A and B.
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Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli.
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Sustained release of BMP-2 in a lipid-based microtube vehicle.
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Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients.
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Synthetic bone mimetic matrix-mediated in situ bone tissue formation through host cell recruitment.
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T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair.
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TCDD disrupts hypural skeletogenesis during medaka embryonic development.
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Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage.
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The DVR gene family in embryonic development.
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The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.
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The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis.
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The development of the upper end of the femur, with special reference to its internal architecture.
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The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice.
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The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.
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The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis.
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The use of a Type-I lyophilisate collagen as an osteoinductive factor in pseudarthroses of the forearm.
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Use of a revascularized, tubed costal myoperiosteal graft for repair of circumferential, segmental tracheal defects.
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Keywords of People
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Freemark, Michael Scott,
Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine,
Pediatrics, Endocrinology
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Hogan, Brigid L. M.,
George Barth Geller Distinguished Professor for Research in Molecular Biology,
Cell Biology
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McDonnell, Donald Patrick,
Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine,
Duke Innovation & Entrepreneurship
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Olson, Steven Arthur,
Professor of Orthopaedic Surgery,
Orthopaedics