Ovalbumin

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  Subject Areas on Research

  • A rapid method for the isolation and partial purification of specific eucaryotic messenger RNA's. 
  • A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination. 
  • A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized 3He MRI. 
  • A self-assembling peptide acting as an immune adjuvant. 
  • Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma. 
  • Allergen-induced airway disease is mouse strain dependent. 
  • Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen. 
  • Analysis of NLRP3 in the development of allergic airway disease in mice. 
  • Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmin, angiotensinogen, and ovalbumin. 
  • Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways. 
  • Antigen delivery by alpha(2)-macroglobulin enhances the cytotoxic T lymphocyte response. 
  • Antigen-presenting cells pulsed with unfractionated tumor-derived peptides are potent tumor vaccines. 
  • Assessment of sex steroid action in vitro. 
  • Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis. 
  • Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease. 
  • CD19 expression in B cells regulates atopic dermatitis in a mouse model. 
  • CaMKII is essential for the proasthmatic effects of oxidation. 
  • Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides. 
  • Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with non-replicating antigens. 
  • Chronic aspiration shifts the immune response from Th1 to Th2 in a murine model of asthma. 
  • Chronic aspiration shifts the immune response from adaptive immunity to innate immunity in a murine model of asthma. 
  • Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice. 
  • Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophilic polylysines. 
  • Comparative studies on the secondary structure of ovalbumin messenger RNA and its complementary DNA transcript. 
  • Conditional knockout of the RNA-binding protein HuR in CD4⁺ T cells reveals a gene dosage effect on cytokine production. 
  • Consistent production of transgenic chickens using replication-deficient retroviral vectors and high-throughput screening procedures. 
  • Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo. 
  • Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells. 
  • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. 
  • Effect of estrogen on the synthesis and processing of ovalbumin messenger RNA in the chick oviduct. 
  • Effects of corticosteroid treatment on airway inflammation, mechanics, and hyperpolarized ³He magnetic resonance imaging in an allergic mouse model. 
  • Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. 
  • Estrogen induction of ovalbumin mRNA: evidence for transcription control. 
  • Estrogen-induced changes in translation, and specific messenger RNA levels during oviduct differentiation. 
  • Estrogen-induced synthesis of ovalbumin messenger RNA and its translation in a cell-free system. 
  • Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology. 
  • Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. 
  • Flow cytometry sorting of recombinant mycobacterial species yields bacterial clones with enhanced insert expression. 
  • High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade. 
  • IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens. 
  • Immune modulatory oligonucleotides in prevention of nasal allergen-induced Eustachian tube dysfunction in rats. 
  • Immune modulatory oligonucleotides in the prevention and treatment of OVA-induced eustachian tube dysfunction in rats. 
  • Immunologic characterization of CD7-deficient mice. 
  • Immunomodulator effect of picroliv and its potential in treatment against resistant Plasmodium yoelii (MDR) infection in mice. 
  • In vitro exposure to nitrogen dioxide (NO2) does not alter bronchial smooth muscle responsiveness in ovalbumin-sensitized guinea-pigs. 
  • In vivo cytotoxic T lymphocyte induction with soluble proteins administered in liposomes. 
  • In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations. 
  • In vivo studies in C4-deficient guinea pigs. 
  • In-vivo impaired T helper 1 cell development in submandibular lymph nodes due to IL-12 deficiency following antigen injection into the anterior chamber of the eye. 
  • Increased surfactant protein D in rat airway goblet and Clara cells during ovalbumin-induced allergic airway inflammation. 
  • Induction of specific translatable messenger RNA's by oestrogen and progesterone. 
  • Intranasal immunization with CTL epitope peptides from HIV-1 or ovalbumin and the mucosal adjuvant cholera toxin induces peptide-specific CTLs and protection against tumor development in vivo. 
  • Intranasal immunization with cytotoxic T-lymphocyte epitope peptide and mucosal adjuvant cholera toxin: selective augmentation of peptide-presenting dendritic cells in nasal mucosa-associated lymphoid tissue. 
  • Involvement of an ATP-dependent peptide chaperone in cross-presentation after DNA immunization. 
  • Involvement of corneal lymphangiogenesis in a mouse model of allergic eye disease. 
  • Isolation of protein factors from oviduct polysomes which stimulate protein synthesis. 
  • L-Selectin is required for the development of airway hyperresponsiveness but not airway inflammation in a murine model of asthma. 
  • L-selectin and intercellular adhesion molecule 1 mediate lymphocyte migration to the inflamed airway/lung during an allergic inflammatory response in an animal model of asthma. 
  • Liposomes as antigen delivery systems in viral immunity. 
  • Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation. 
  • Mast Cell Deficiency Limits the Development of Chronic Rhinosinusitis in Mice. 
  • Mechanism of estrogen action: early transcriptional and translational events. 
  • Methods to Investigate the Roles for β-Arrestin-2 in Allergic Inflammatory Airway Disease. 
  • Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. 
  • Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis. 
  • Modulating adaptive immune responses to peptide self-assemblies. 
  • Mucosal and systemic adjuvant activity of alphavirus replicon particles. 
  • Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness. 
  • Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis. 
  • Nucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responses. 
  • Ocular allergy modulation to hi-dose antigen sensitization is a Treg-dependent process. 
  • Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector. 
  • Oral immunogenicity of the plant proteinase bromelain. 
  • Ovalbumin gene: purification of the coding strand. 
  • Ovalbumin messenger RNA of chick oviduct: partial characterization, estrogen dependence, and translation in vitro. 
  • Partial purification of a progesterone-inducible messenger RNA (avidin) from hen oviduct. 
  • Physical and chemical characterization of purified ovalbumin messenger RNA. 
  • Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct. 
  • Prevention of graft-versus-host disease by peptides binding to class II major histocompatibility complex molecules. 
  • Processing of nuclear heterogeneous RNA: recent developments. 
  • Protection from experimental asthma by an endogenous bronchodilator. 
  • Protein biosynthesis on chick oviduct polyribosomes. II. Regulation by progesterone. 
  • Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. 
  • Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Rates of induction of specific translatable messenger RNAs for ovalbumin and avidin by steroid hormones. 
  • Redundancy renders the glycoprotein 96 receptor scavenger receptor A dispensable for cross priming in vivo. 
  • Regulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation. 
  • Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice. 
  • Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model. 
  • Role of chaperones in antigen processing. 
  • Role of interleukin 12 and costimulators in T cell anergy in vivo. 
  • Role of macrophages and dendritic cells in primary cytotoxic T lymphocyte responses. 
  • Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection. 
  • S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction. 
  • Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. 
  • Secondary structure of ovalbumin messenger RNA. 
  • Soluble proteins delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro. 
  • Steroid hormone induction of a specific translatable messenger RNA. 
  • Steroid hormone regulation of specific gene expression. 
  • Steroid hormone regulation of specific messenger RNA and protein synthesis in eucaryotic cells. 
  • Stimulation of cell-free polypeptide synthesis by a protein fraction extracted from chick oviduct polyribosomes. 
  • Substance P dependence of endosomal fusion during bladder inflammation. 
  • Synergy of adoptive T-cell therapy and intratumoral suicide gene therapy is mediated by host NK cells. 
  • Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. 
  • T-cell-receptor affinity and thymocyte positive selection. 
  • TLR4 signaling attenuates ongoing allergic inflammation. 
  • Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes. 
  • The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines. 
  • The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. 
  • The mechanism of steroid-hormone regulation of transcription of specific eukaryotic genes. 
  • The ovalbumin gene. Partial purification of the coding strand. 
  • Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease. 
  • This paper is the winner of an SFB Award in the Hospital Intern, Residency category: Peptide biomaterials raising adaptive immune responses in wound healing contexts. 
  • Transfer of CD8+ T cell memory using Bcl-2 as a marker. 
  • Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. 
  • Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts. 
  • Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. 
  • Very high pressure gradient LC/MS/MS. 
  • Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96. 
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  Keywords of People

  • Driehuys, Bastiaan, Professor of Radiology, Physics
  • Gunn, Michael Dee, Professor of Medicine, Immunology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology