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Subject Areas on Research
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2-Methoxyestradiol, an endogenous estradiol metabolite, differentially inhibits granulosa and endothelial cell mitosis: a potential follicular antiangiogenic regulator.
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A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'.
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A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
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A grafted ovarian fragment rescues host fertility after chemotherapy.
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A molecular analysis of hyalin--a substrate for cell adhesion in the hyaline layer of the sea urchin embryo.
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Abundance and Localization of Progesterone Receptor Isoforms in Endometrium in Women With and Without Endometriosis and in Peritoneal and Ovarian Endometriotic Implants.
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Acute and subacute effects of naturally occurring estrogens on luteinizing hormone secretion in the ovariectomized rat: Part 1.
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Acute and subacute effects of naturally occurring estrogens on luteinizing hormone secretion in the ovariectomized rat: Part 2.
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Adjunctive leuprolide therapy does not improve cycle fecundity in controlled ovarian hyperstimulation and intrauterine insemination of subfertile women.
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Alterations in luteal phase progesterone and estradiol production after leuprolide acetate therapy before ovarian stimulation for in vitro fertilization.
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Anti-Müllerian hormone: a better marker of ovarian damage from cyclophosphamide.
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Application of a modified 203Hg binding assay for metallothionein.
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Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.
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BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.
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BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.
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BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.
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Balancing the bipotential gonad between alternative organ fates: a new perspective on an old problem.
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Bioaccumulation and speciation of selenium in fish and insects collected from a mountaintop removal coal mining-impacted stream in West Virginia.
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Biochemical and toxicopathic biomarkers assessed in smallmouth bass recovered from a polychlorinated biphenyl-contaminated river.
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Biochemical identification of apoptosis (programmed cell death) in granulosa cells: evidence for a potential mechanism underlying follicular atresia.
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Bmp7 regulates germ cell proliferation in mouse fetal gonads.
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CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.
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Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression.
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Cellular and molecular pathways regulating mammalian sex determination.
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Changes in calmodulin and its mRNA accompany reentry of quiescent (G0) cells into the cell cycle.
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Changes in gene expression associated with reproductive maturation in wild female baboons.
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Characterization of DNA lesions induced by CaCrO4 in synchronous and asynchronous cultured mammalian cells.
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Citation for the 1998 Gerald D. Aurbach Lecture Award of the Endocrine Society to Dr. JoAnne S. Richards.
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Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer.
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Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor.
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Combined iDISCO and CUBIC tissue clearing and lightsheet microscopy for in toto analysis of the adult mouse ovary†.
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Common variants at 19p13 are associated with susceptibility to ovarian cancer.
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Comparison of the ultrasonic scalpel to CO2 laser and electrosurgery in terms of tissue injury and adhesion formation in a rabbit model.
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Compartmental ovarian steroidogenesis in polycystic ovary syndrome.
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Conserved action of β-catenin during female fate determination in the red-eared slider turtle.
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Constitutive production of macrophage colony-stimulating factor and interleukin-6 by human ovarian surface epithelial cells.
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Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium.
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Cushing syndrome, sexual precocity, and polyostotic fibrous dysplasia (Albright syndrome) in infancy.
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DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells.
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Development of the external genitalia: perspectives from the spotted hyena (Crocuta crocuta).
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Diagnosis of ectopic pregnancy.
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Different secretory pathways of renin from mouse cells transfected with the human renin gene.
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Differential expression of p63 isoforms in female reproductive organs.
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Differential replication of satellite DNA in polyploid tissues of Drosophila virilis.
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Differential screening of a subtracted cDNA library: a method to search for genes preferentially expressed in multiple tissues.
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Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance.
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Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.
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Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.
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Dynamic reciprocity between cells and their microenvironment in reproduction.
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Dysgenesis of testicular and streak gonads in the syndrome of mixed gonadal dysgenesis: perspective derived from a clinicopathologic analysis of twenty-one cases.
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EFFECTS OF 6 ALPHA-METHYL-17-ACETOXYPROGESTERONE, 17 ALPHA-ETHYNYL-19-NORTESTOSTERONE, PROGESTERONE, AND TESTOSTERONE PROPIONATE ON THE ADRENALS, GONADS, AND BURSA OF FABRICIUS OF THE CHICKEN.
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ELECTROPHORETIC SEPARATION OF HYDROLYTIC ENZYMES OF THE FEMALE RAT REPRODUCTIVE TRACT.
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Effect of hysterectomy with ovarian preservation on ovarian function.
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Effect of neonatal diethylstilbestrol exposure on luteinizing hormone secretion following ketamine anesthesia and gonadotropin-releasing hormone in castrated postpubertal rats.
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Effect of progestin on the ovarian epithelium of macaques: cancer prevention through apoptosis?
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Effects of charcoal-extracted follicular fluid on reproductive function in postpartum cows.
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Effects of phytoestrogens on GnRH-induced luteinizing hormone secretion in ovariectomized rats.
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Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation.
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Embolic microspheres within ovarian arterial vasculature after uterine artery embolization.
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Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. I. Correlation of receptor expression with prognostic factors in patients with ovarian cancer.
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Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. II. Relationship between receptor expression and response to epidermal growth factor.
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Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia.
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Equivalency of human menopausal gonadotropin and follicle-stimulating hormone stimulation after gonadotropin-releasing hormone agonist suppression.
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Etiology of closure-related adhesion formation after wedge resection of the rabbit ovary.
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Eukaryotic gene transcription with purified components.
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Evidence for transovarial transmission of tick-borne rickettsiae circulating in Northern Mongolia.
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Expression of parathyroid hormone-related peptide (PTH-rp) and its receptorin the porcine ovary: regulation by transforming growth factor-beta and possible paracrine effects of granulosa cell PTH-rp secretion on theca cells.
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Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.
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FGF9 promotes survival of germ cells in the fetal testis.
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FMRP targets distinct mRNA sequence elements to regulate protein expression.
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Female fertility is reduced in mice lacking Ca2+/calmodulin-dependent protein kinase IV.
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Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice.
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Fertilization and in vitro development of cryopreserved human prophase I oocytes.
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Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.
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Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination.
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Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.
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Four-dimensional analysis of vascularization during primary development of an organ, the gonad.
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Further studies on the role of the gonads in determining the ontogeny of gonadotropin secretion in the guinea pig (Cavia porcelus).
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GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila.
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Gene expression patterns that characterize advanced stage serous ovarian cancers.
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Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.
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Germ cell depletion does not alter the morphogenesis of the fetal testis or ovary in the red-eared slider turtle (Trachemys scripta).
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Germ cells are not required to establish the female pathway in mouse fetal gonads.
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Gonad morphogenesis in vertebrates: divergent means to a convergent end.
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Growth and development following marrow transplantation for leukemia.
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Growth inhibition and metallothionein induction in cadmium-resistant cells by essential and non-essential metals.
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Growth regulation and transformation of ovarian epithelium.
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Helicobacter infection decreases reproductive performance of IL10-deficient mice.
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High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated preoperative serum levels.
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Histotype classification of ovarian carcinoma: A comparison of approaches.
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Human G(alpha q): cDNA and tissue distribution.
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Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA.
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Human ovarian cancer of the surface epithelium.
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Hypertrophy of basal forebrain neurons and enhanced visuospatial memory in perinatally choline-supplemented rats.
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Identification of genes associated with ovarian cancer metastasis using microarray expression analysis.
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Identification of potassium-dependent and -independent components of the apoptotic machinery in mouse ovarian germ cells and granulosa cells.
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In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization.
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Increased blood pressure in mice lacking cytochrome P450 2J5.
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Individual differences in psychostimulant responses of female rats are associated with ovarian hormones and dopamine neuroanatomy.
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Insular carcinoid primary in the ovary. A clinicopathologic analysis of 48 cases.
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Long-term results of therapy for stage C neuroblastoma.
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Male-to-female sex reversal in mice lacking fibroblast growth factor 9.
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Malignant struma ovarii: a blinded study of 86 cases assessing which histologic features correlate with aggressive clinical behavior.
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Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration.
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Mechanical signaling in reproductive tissues: mechanisms and importance.
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Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads.
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Microarray gene expression profiles from mature gonad tissues of Atlantic bluefin tuna, Thunnus thynnus in the Gulf of Mexico.
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Modeling endocrine control of the pituitary-ovarian axis: androgenic influence and chaotic dynamics.
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Molecular determinants of sexual differentiation.
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Multi-modal magnetic resonance elastography for noninvasive assessment of ovarian tissue rigidity in vivo.
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Mutation and overexpression of p53 in early-stage epithelial ovarian cancer.
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Müllerian inhibiting substance: gene structure and mechanism of action of a fetal regressor.
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Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development.
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Non-functional ovarian cysts do not affect ipsilateral or contralateral ovarian performance during in-vitro fertilization.
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Nonsteroidal antiinflammatory drugs and progestins synergistically enhance cell death in ovarian epithelial cells.
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Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice.
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Observations of tissue response to acoustic radiation force: opportunities for imaging.
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One tissue, two fates: molecular genetic events that underlie testis versus ovary development.
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Oocyte Cryopreservation for Fertility Preservation in Healthy Women.
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Oocyte cryopreservation versus ovarian tissue cryopreservation for adult female oncofertility patients: a cost-effectiveness study.
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Ovarian ablation in early breast cancer: overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.
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Ovarian epithelium regeneration by Lgr5(+) cells.
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Ovarian function following marrow transplantation for aplastic anemia or leukemia.
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Ovarian preservation by GnRH agonists during chemotherapy: a meta-analysis.
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Ovarian reserve diminished by oral cyclophosphamide therapy for granulomatosis with polyangiitis (Wegener's).
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Ovarian stimulation for in vitro fertilization in low-responder patients using pulsatile intravenous follicle stimulating hormone.
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Ovarian stimulation for in vitro fertilization using pure follicle-stimulating hormone with and without gonadotropin-releasing hormone agonist in high-responder patients.
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Ovarian vein thrombosis in oncology patients: CT detection and clinical significance.
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Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila.
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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
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Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas.
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Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer.
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Predetermination of sexual fate in a turtle with temperature-dependent sex determination.
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Preferential DNA-protein cross-linking by NiCl2 in magnesium-insoluble regions of fractionated Chinese hamster ovary cell chromatin.
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Prevalence and management of ovarian venous insufficiency in the presence of leg venous insufficiency.
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Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse.
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Progestin-induced apoptosis in the Macaque ovarian epithelium: differential regulation of transforming growth factor-beta.
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Prostaglandin F 2 alpha production by the human ovary.
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Prostaglandin F2alpha levels in human ovarian plasma in pregnancy and in a case of Halban's disease.
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RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.
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Radiation synovectomy with 165Dy-FHMA: lymph node uptake and radiation dosimetry calculations.
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Randomized trial to compare the effect of recombinant human FSH (follitropin alfa) with or without recombinant human LH in women undergoing assisted reproduction treatment.
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Reduction of granulosa cell progesterone secretion in vitro by intraovarian implants of antiandrogen.
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Regional-specific effects of ovarian hormone loss on synaptic plasticity in adult human APOE targeted replacement mice.
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Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor beta.
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Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-beta.
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Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells.
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Reproductive hormone levels in gynecologic oncology patients undergoing surgical castration after spontaneous menopause.
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Requirement for JAK/STAT signaling throughout border cell migration in Drosophila.
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Resistance of the male gonad to a high galactose diet.
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Results of in vitro fertilization attempts in patients with one or two ovaries.
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Retinoic acid regulates sex-specific timing of meiotic initiation in mice.
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Right gonadal vein transposition for the treatment of anterior nutcracker syndrome in a patient with left-sided inferior vena cava.
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Role of Increased n-acetylaspartate Levels in Cancer.
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Role of placental lactogen and prolactin in human pregnancy.
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Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma.
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Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis.
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Serum concentrations of deoxycorticosterone in women during the luteal phase of the ovarian cycle are not suppressed by dexamethasone treatment.
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Sex and the circuitry: progress toward a systems-level understanding of vertebrate sex determination.
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Sex hormones and renal nitric oxide synthases.
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Significance of basal follicle-stimulating hormone levels in women with one ovary in a program of in vitro fertilization.
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Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal.
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Steroidogenic factor 1 (SF-1) is essential for ovarian development and function.
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Stimulation protocols for patients with "atypical response".
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Stress affects uterine receptivity through an ovarian-independent pathway.
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Stretching the surface epithelium.
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Subcellular localization of the human immunodeficiency virus trans-acting art gene product.
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Suppression and flare regimens of gonadotropin-releasing hormone agonist. Use in women with different basal gonadotropin values in an in vitro fertilization program.
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Symptoms of Women With High-Risk Early-Stage Ovarian Cancer.
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Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult.
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Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
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Temperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculus.
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Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice.
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Testing and interpreting measures of ovarian reserve: a committee opinion.
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Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila.
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The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus.
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The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-A potential therapeutic target.
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The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.
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The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3).
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The battle of the sexes.
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The effect of interferon gamma on epidermal growth factor receptor expression in normal and malignant ovarian epithelial cells.
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The gene encoding vitamin K-dependent anticoagulant protein S is expressed in multiple rabbit organs as demonstrated by northern blotting, in situ hybridization, and immunohistochemistry.
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The gonadotropin-releasing hormone agonist stimulation test--a sensitive predictor of performance in the flare-up in vitro fertilization cycle.
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The molecular pharmacology of ovarian steroid receptors.
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The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development.
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The naturally occurring luteinizing hormone surge is diminished in mice lacking estrogen receptor Beta in the ovary.
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The presence of receptors for bombesin/GRP and mRNA for three receptor subtypes in human ovarian epithelial cancers.
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The value of basal serum follicle stimulating hormone, luteinizing hormone and oestradiol concentrations following pituitary down-regulation in predicting ovarian response to stimulation with highly purified follicle stimulating hormone.
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Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues.
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Time-resolved MR angiography as a useful sequence for assessment of ovarian vein reflux.
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Tissue and cellular alterations in Asian clam (Potamocorbula amurensis) from San Francisco Bay: toxicological indicators of exposure and effect?
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Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish.
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Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus.
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Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression.
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Two forms of mitochondrial DNA ligase III are produced in Xenopus laevis oocytes.
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Unilateral luteoma of pregnancy mimicking a malignant ovarian mass on magnetic resonance and ultrasound.
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Use of gonadotrophin-releasing hormone agonists in controlled ovarian hyperstimulation for in vitro fertilization.
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Uterine blood flow: periodic fluctuations of its rate during pregnancy.
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Variations of light and temperature regimes and resulting effects on reproductive parameters in medaka (Oryzias latipes).
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Virilization during pregnancy associated with polycystic ovary disease.
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Visualization of replication initiation and elongation in Drosophila.
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WOMEN IN REPRODUCTIVE SCIENCE: To be or not to be a testis.
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[Krukenberg tumor: a clinical case report].
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ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets.
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Keywords of People
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Allen, Nancy Bates,
Professor Emeritus of Medicine,
Medicine, Rheumatology and Immunology
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Moorman, Patricia Gripka,
Professor Emeritus in Family Medicine and Community Health,
Duke Cancer Institute