Embryo Implantation

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  Subject Areas on Research

  • A comparative analysis of embryo implantation potential in patients with severe teratozoospermia undergoing in-vitro fertilization with a high insemination concentration or intracytoplasmic sperm injection. 
  • A comparison of the relative efficiency of ICSI and extended culture with epididymal sperm versus testicular sperm in patients with obstructive azoospermia. 
  • A review of endometrium and implantation. 
  • Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium. 
  • Analysis of implantation in assisted reproduction through the use of serial human chorionic gonadotropin measurements. 
  • Are implantation and pregnancy outcome impaired in diethylstilbestrol-exposed women after in vitro fertilization and embryo transfer? 
  • Basal follicle-stimulating hormone level is a better predictor of in vitro fertilization performance than age. 
  • Carbohydrate changes in pre- and peri-implantation mouse embryos as detected by a monoclonal antibody. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization. 
  • Defining recurrent implantation failure: a profusion of confusion or simply an illusion? 
  • Diagnostic and therapeutic options in recurrent implantation failure. 
  • Dose-dependent number of implants and implications in developmental toxicity. 
  • Embryo implantation in in vitro fertilization and intracytoplasmic sperm injection: impact of cleavage status, morphology grade, and number of embryos transferred. 
  • Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment. 
  • Endometrial receptivities after leuprolide suppression and gonadotropin stimulation: histology, steroid receptor concentrations, and implantation rates. 
  • Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis. 
  • Endometrial receptivity: lessons from systems biology and candidate gene studies of endometriosis. 
  • Evaluation of endometrial receptivity and implantation failure. 
  • FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation. 
  • High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes. 
  • Homeostasis imbalance in the endometrium of women with implantation defects: the role of estrogen and progesterone. 
  • Hormone control and expression of androgen receptor coregulator MAGE-11 in human endometrium during the window of receptivity to embryo implantation. 
  • Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial Regulators. 
  • Immunologic challenges of human reproduction: an evolving story. 
  • Impact of intracytoplasmic sperm injection on embryo cryopreservation and clinical outcome. 
  • Implantation and pregnancy rates in relation to oestradiol and progesterone profiles in cycles with and without the use of gonadotrophin-releasing hormone agonist suppression. 
  • Implantation and the survival of early pregnancy. 
  • Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium. 
  • Is the timing of implantation affected by zona pellucida micromanipulation? 
  • Joint models for toxicology studies with dose-dependent number of implantations. 
  • Loss of HDAC3 results in nonreceptive endometrium and female infertility. 
  • Modeling human peri-implantation placental development and function†. 
  • Modulation of implantation-associated integrin expression but not uteroglobin by steroid hormones in an endometrial cell line. 
  • Msx Homeobox Genes Act Downstream of BMP2 to Regulate Endometrial Decidualization in Mice and in Humans. 
  • Natural limits of pregnancy testing in relation to the expected menstrual period. 
  • Nuclear pore complex proteins mark the implantation window in human endometrium. 
  • Obstetrician-gynecologists' beliefs about when pregnancy begins. 
  • Oestrogen and progesterone action on endometrium: a translational approach to understanding endometrial receptivity. 
  • Peri-implantation intercourse lowers fecundability. 
  • Podocalyxin is a key negative regulator of human endometrial epithelial receptivity for embryo implantation. 
  • Pre-implantation genetic testing alters the sex ratio: an analysis of 91,805 embryo transfer cycles. 
  • Predictive value of pregnancy during original in vitro fertilization cycle on implantation and pregnancy in subsequent cryothaw cycles. 
  • Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008-2010 Society for Assisted Reproductive Technology registry. 
  • Pregnancy outcomes decline with increasing recipient body mass index: an analysis of 22,317 fresh donor/recipient cycles from the 2008-2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry. 
  • Pregnancy rates in donor oocyte cycles compared to similar autologous in vitro fertilization cycles: an analysis of 26,457 fresh cycles from the Society for Assisted Reproductive Technology. 
  • Primate-specific melanoma antigen-A11 regulates isoform-specific human progesterone receptor-B transactivation. 
  • Prospective assessment of midsecretory endometrial leukemia inhibitor factor expression versus ανβ3 testing in women with unexplained infertility. 
  • Proteomic analysis of endometrium from fertile and infertile patients suggests a role for apolipoprotein A-I in embryo implantation failure and endometriosis. 
  • Randomized trial to compare the effect of recombinant human FSH (follitropin alfa) with or without recombinant human LH in women undergoing assisted reproduction treatment. 
  • Regulated expression of heparin-binding EGF-like growth factor (HB-EGF) in the human endometrium: a potential paracrine role during implantation. 
  • Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique outcomes. 
  • Role of SIRT1 and Progesterone Resistance in Normal and Abnormal Endometrium. 
  • SIRT1 plays an important role in implantation and decidualization during mouse early pregnancy. 
  • SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts. 
  • Should we stop offering endometrial scratching prior to in vitro fertilization? 
  • Sonographic appearance of the endometrium: the predictive value for the outcome of in-vitro fertilization in stimulated cycles. 
  • Stress affects uterine receptivity through an ovarian-independent pathway. 
  • Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion. 
  • The endometria of women with endometriosis exhibit dysfunctional expression of complement regulatory proteins during the mid secretory phase. 
  • The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. 
  • The significance of hydrosalpinx in in vitro fertilization. 
  • Transfer of cryopreserved-thawed pre-embryos in a cycle using exogenous steroids without prior gonadotrophin-releasing hormone agonist suppression yields favourable pregnancy results. 
  • Transfer of cryopreserved-thawed pre-embryos in a natural cycle or a programmed cycle with exogenous hormonal replacement yields similar pregnancy results. 
  • Ultrasonographic appearance of the endometrium in natural and stimulated in-vitro fertilization cycles and its correlation with outcome. 
  • What exactly is endometrial receptivity? 
  • siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth. 
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  Keywords of People

  • Erickson, Harold Paul, Professor Emeritus of Cell Biology, Cell Biology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology