Oxadiazoles
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Subject Areas on Research
- Ataluren treatment of patients with nonsense mutation dystrophinopathy.
- Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
- Characterization of nucleotide binding sites on chloroplast coupling factor 1.
- Concentration-related effects of nitric oxide and endothelin-1 on human trabecular meshwork cell contractility.
- DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder.
- Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones.
- Evidence for differential localization of two binding sites for L-[3H]glutamate in rat fascia dentata.
- Fluorescence energy transfer between ligand binding sites on chloroplast coupling factor 1.
- Gut hormone pharmacology of a novel GPR119 agonist (GSK1292263), metformin, and sitagliptin in type 2 diabetes mellitus: results from two randomized studies.
- In vivo staining of cytoskeletal actin by autointernalization of nontoxic concentrations of nitrobenzoxadiazole-phallacidin.
- Initial testing (stage 1) of BAL101553, a novel tubulin binding agent, by the pediatric preclinical testing program.
- Initial testing (stage 1) of the Akt inhibitor GSK690693 by the pediatric preclinical testing program.
- Kinetic and structural investigation of acyl-binding sites on avian fatty acid synthase.
- L-[3H]Glutamate binding to hippocampal synaptic membranes: two binding sites discriminated by their differing affinities for quisqualate.
- Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo.
- Properties of rabbit muscle phosphofructokinase modified with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole.
- Protein-protein and protein-DNA interactions at the bacteriophage T4 DNA replication fork. Characterization of a fluorescently labeled DNA polymerase sliding clamp.
- S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection.
- S1P₂ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology.
- Selective and reversible increase in the number of quisqualate-sensitive glutamate binding sites on hippocampal synaptic membranes after angular bundle kindling.
- Selective increase in L-[3H]glutamate binding to a quisqualate-sensitive site on hippocampal synaptic membranes after angular bundle kindling.
- cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
- β-Cell Inactivation of Gpr119 Unmasks Incretin Dependence of GPR119-Mediated Glucoregulation.