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Subject Areas on Research
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2-Azadienes as Reagents for Preparing Chiral Amines: Synthesis of 1,2-Amino Tertiary Alcohols by Cu-Catalyzed Enantioselective Reductive Couplings with Ketones.
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57Fe and 1H electron-nuclear double resonance of three doubly reduced states Escherichia coli sulfite reductase.
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De Novo
Design, Solution Characterization, and Crystallographic Structure of an Abiological Mn-Porphyrin-Binding Protein Capable of Stabilizing a Mn(V) Species.
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A Convenient Synthesis of Cis and Trans 4-tert-Butoxycarbonyl-Substituted Cyclohexylglycine
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A Diastereodivergent and Enantioselective Approach to syn
- and anti
-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines That Furnish Allylic Amines.
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A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.
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A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia.
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A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination.
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A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP5+, Synergizes with Carboplatin in Treatment of Chemoresistant Ovarian Cell Line.
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A Single Bout of Premeal Resistance Exercise Improves Postprandial Glucose Metabolism in Obese Men with Prediabetes.
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A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
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A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species.
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A comparative study of antioxidative activities of cell-wall polysaccharides.
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A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments.
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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics.
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A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.
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A differential role for endocytosis in receptor-mediated activation of Nox1.
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A formal synthesis of SCH 351448.
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A generic emergency protocol for patients with inborn errors of metabolism causing fasting intolerance: A retrospective, single-center study and the generation of www.emergencyprotocol.net.
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A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.
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A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals.
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A hot spot for hydrogen peroxide-induced damage in the human hypoxia-inducible factor 1 binding site of the PGK 1 gene.
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A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats.
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A mechanism-based antioxidant approach for the reduction of skin carcinogenesis.
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A new era for electron bifurcation.
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A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase.
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A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report.
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A photolabile ligand for light-activated release of caged copper.
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A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.
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A simplified method for monitoring the cytochrome aa3 redox state in bilateral cortical areas of unanesthetized cats.
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A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability.
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A spectroelectrochemical method for differentiation of steric and electronic effects in hemoglobins and myoglobins.
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A study of the binding of thiamine diphosphate and thiochrome diphosphate to the pyruvate dehydrogenase multienzyme complex.
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A television fluorometer for monitoring oxidative metabolism in intact tissue.
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A three-stage symbiosis forms the foundation of seagrass ecosystems.
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Ab initio quantum mechanical/molecular mechanical simulation of electron transfer process: fractional electron approach.
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Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.
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Accurate Quantum Mechanical/Molecular Mechanical Calculations of Reduction Potentials in Azurin Variants.
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Acetate promotes microbial reductive debromination of tetrabromobisphenol A during the startup phase of anaerobic wastewater sludge bioreactors.
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Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat.
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Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria.
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Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: voltammetric and chronocoulometric study of protolytic and redox equilibria.
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Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.
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Active-site heterogeneity in Limulus hemocyanin as revealed by reaction with peroxides.
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Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice.
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Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish.
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Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency.
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Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver.
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Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase.
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Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders.
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Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.
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Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis.
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Age attenuates leucine oxidation after eccentric exercise.
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Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.
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Age-dependent in situ hepatic and gill CYP1A activity in the see-through medaka (Oryzias latipes).
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Age-related metabolic fatigue during low glucose conditions in rat hippocampus.
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Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells.
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Alkaline low spin form of sulfite reductase hemeprotein subunit.
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Allosteric cooperation in a de novo-designed two-domain protein.
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Altered mitochondrial redox responses in gram negative septic shock in primates.
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Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides.
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An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation.
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An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides.
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An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake.
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An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation.
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Anaerobic oxidations of myoglobin and hemoglobin by spectroelectrochemistry.
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Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide.
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Animal models of steatohepatitis.
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Animal models of steatosis.
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Anthracenedione antineoplastic agent effects on drug metabolism in vitro and in vivo: relationship between structure and mechanism of inhibition.
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Anti-c-myc DNA increases differentiation and decreases colony formation by HL-60 cells.
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Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor.
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Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut.
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Anticancer therapeutic potential of Mn porphyrin/ascorbate system.
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Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish.
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Application of Cobalt/Peracetic Acid to Degrade Sulfamethoxazole at Neutral Condition: Efficiency and Mechanisms.
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Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes.
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Ascorbic acid accumulates in cartilage in vivo.
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Assay and detection of the molybdenum cofactor.
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Assessment and application of the biotin switch technique for examining protein S-nitrosylation under conditions of pharmacologically induced oxidative stress.
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Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac catheterization cohort.
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AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment.
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Augmented TNF-alpha and IL-10 production by primed human monocytes following interaction with oxidatively modified autologous erythrocytes.
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BCAA Supplementation in Mice with Diet-induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis.
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Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology.
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Bacteriophage inactivation by UV-A illuminated fullerenes: role of nanoparticle-virus association and biological targets.
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Bench-to-bedside review: sepsis - from the redox point of view.
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Berninamycin. 2. Products of acidic hydrolysis, methanolysis, and acetolysis of berninamycin A1.
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Binding of native and reduced and carbamidomethylated hGH to rabbit liver plasma membranes.
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Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site.
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Biochemical Underpinnings of Immune Cell Metabolic Phenotypes.
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Biochemical and structural studies of tenascin/hexabrachion proteins.
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Biocompatibility studies of functionalized regioregular poly(3-hexylthiophene) layers for sensing applications.
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Biological assessment of bisphenol A degradation in water following direct photolysis and UV advanced oxidation.
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Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H2O2 oxidation.
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Biological charge transfer via flickering resonance.
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Bis(alkylamino)anthracenedione antineoplastic agent metabolic activation by NADPH-cytochrome P-450 reductase and NADH dehydrogenase: diminished activity relative to anthracyclines.
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Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome.
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Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight.
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Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure.
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CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC.
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CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis.
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CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells.
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CaMKII is essential for the proasthmatic effects of oxidation.
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Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.
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Calculating solution redox free energies with ab initio quantum mechanical/molecular mechanical minimum free energy path method.
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Capillary electrophoresis with solid-state electrochemiluminescence detector.
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Carbon monoxide-cytochrome interactions in the brain of the fluorocarbon-perfused rat.
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Carbon monoxide-driven reduction of ferric heme and heme proteins.
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Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
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Cardioprotective role of S-nitrosylated hemoglobin from rbc.
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Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs.
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Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
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Cell-free hemoglobin reverses the endotoxin-mediated hyporesponsivity of rat aortic rings to alpha-adrenergic agents.
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Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors.
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Cerebral bioenergetics and in vivo cytochrome c oxidase redox relationships.
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Cerebral cortical microfluorometry at isosbestic wavelengths for correction of vascular artifact.
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Cerebrocortical oxygenation and ventilatory response during sustained hypoxia.
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Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues.
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Changes in Oxidant Defense, Apoptosis, and Cognitive Abilities During Treatment for Childhood Leukemia.
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Changes in cerebral blood volume and cytochrome aa3 during hypertensive peaks in preterm infants.
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Characterisation of PduS, the pdu metabolosome corrin reductase, and evidence of substructural organisation within the bacterial microcompartment.
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Characterization of Fe(III) sequestration by an analog of the cytotoxic siderophore brasilibactin A: implications for the iron transport mechanism in mycobacteria.
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Characterization of a new model of human prostatic cancer: the multicellular tumor spheroid.
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Characterization of a rat type 2 angiotensin II receptor stably expressed in 293 cells.
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Characterization of complexes between Escherichia coli sulfite reductase hemoprotein subunit and its substrates sulfite and nitrite.
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Characterization of human alpha 2-macroglobulin monomers obtained by reduction with dithiothreitol.
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Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique.
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Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation.
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Chemical aspects of siderophore mediated iron transport.
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Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro.
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Chemistry and biology of the molybdenum cofactor.
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Chromatographic analysis and decomposition product characterization of compound SR16157 (NSC 732011).
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Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.
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Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
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Colloid chemical approach to nanoelectrode ensembles with highly controllable active area fraction.
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Cometabolism of cis-1,2-dichloroethene by aerobic cultures grown on vinyl chloride as the primary substrate.
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Compact point-detection fluorescence spectroscopy system for quantifying intrinsic fluorescence redox ratio in brain cancer diagnostics.
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Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach.
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Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans.
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Comparison of systemic oxygen delivery and uptake with NIR spectroscopy of brain during normovolemic hemodilution in the rabbit.
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Comparisons of polychromatic and monochromatic UV-based treatments of bisphenol-A in water via toxicity assessments.
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Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis.
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Compartmentalized nitrosation and nitration in mitochondria.
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Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis: ANAPLEROSIS FROM DODECANEDIOATE.
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Complementation of SOD-deficient Escherichia coli by manganese porphyrin mimics of superoxide dismutase activity.
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Complex chemistry and biology of redox-active compounds, commonly known as SOD mimics, affect their therapeutic effects.
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Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.
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Concentration-dependent effects of anions on the anaerobic oxidation of hemoglobin and myoglobin.
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Concerted O atom-proton transfer in the O-O bond forming step in water oxidation.
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Concordance between trifluoroacetic acid and hepatic protein trifluoroacetylation after disulfiram inhibition of halothane metabolism in rats.
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Conformation change of horseradish peroxidase in lipid membrane.
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Conformational fluctuations in deoxy hemoglobin revealed as a major contributor to anionic modulation of function through studies of the oxygenation and oxidation of hemoglobins A0 and Deer Lodge beta2(NA2)His --> Arg.
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Conformationally averaged score functions for electronic propagation in proteins.
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Consequences of chemical modifications on the free radical reactions of human hemoglobin.
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Constitutive expression of CaPLA1 conferred enhanced growth and grain yield in transgenic rice plants.
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Construction of a novel redox protein by rational design: conversion of a disulfide bridge into a mononuclear iron-sulfur center.
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Control of electron transfer in nitrogenase.
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Conversion between hexagonal GaN and beta-Ga(2)O(3) nanowires and their electrical transport properties.
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Conversion of endogenous indole-3-butyric acid to indole-3-acetic acid drives cell expansion in Arabidopsis seedlings.
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Converting a maltose receptor into a nascent binuclear copper oxygenase by computational design.
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Coordination chemistry of copper proteins: how nature handles a toxic cargo for essential function.
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Copper as a robust and transparent electrocatalyst for water oxidation.
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Coupling coherence distinguishes structure sensitivity in protein electron transfer.
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Critical redox and allosteric aspects of nitric oxide interactions with hemoglobin.
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Critical role of chromium (Cr)-DNA interactions in the formation of Cr-induced polymerase arresting lesions.
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Crystal structure of DMSO reductase: redox-linked changes in molybdopterin coordination.
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Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism.
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Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase.
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Crystallization and preliminary X-ray crystallographic studies of glutaredoxin 2 from Saccharomyces cerevisiae in different oxidation states.
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Cupric-amyloid beta peptide complex stimulates oxidation of ascorbate and generation of hydroxyl radical.
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Curcumin Ameliorates Heat-Induced Injury through NADPH Oxidase-Dependent Redox Signaling and Mitochondrial Preservation in C2C12 Myoblasts and Mouse Skeletal Muscle.
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Cyanide-induced cytochrome a,a3 oxidation-reduction responses in rat brain in vivo.
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Cyclization/hydrosilylation of functionalized 1,6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands.
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Cysteine and glutathione levels in developing rat kidney and liver.
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Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro.
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Cytoprotective effects of proteasome beta5 subunit overexpression in lens epithelial cells.
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Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.
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Cytotoxicity of oxidized LDL to porcine aortic smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol.
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DNA strand breaks following in vitro exposure to asbestos increase with surface-complexed [Fe3+].
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DT diaphorase [NAD(P)H: (quinone acceptor) oxidoreductase] facilitates redox cycling of menadione in channel catfish (Ictalurus punctatus) cytosol.
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Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.
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Degradation and resilience in Louisiana salt marshes after the BP-Deepwater Horizon oil spill.
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Deletion of cysteine 369 in lysyl hydroxylase 1 eliminates enzyme activity and causes Ehlers-Danlos syndrome type VI.
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Dengue virus and autophagy.
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Deoxyribonucleic acid ligase. Isolation and physical characterization of the homogeneous enzyme from Escherichia coli.
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Design and stereoselective preparation of a new class of chiral olefin metathesis catalysts and application to enantioselective synthesis of quebrachamine: catalyst development inspired by natural product synthesis.
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Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity.
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Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.
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Design of bioelectronic interfaces by exploiting hinge-bending motions in proteins.
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Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.
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Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate.
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Detection and characterization of a glutathione conjugate of ochratoxin A.
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Detection and characterization of methionine oxidation in peptides by collision-induced dissociation and electron capture dissociation.
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Detection of protein S-nitrosylation with the biotin-switch technique.
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Determination of the stoichiometry of electron uptake and the midpoint reduction potentials of milk xanthine oxidase at 25 degrees C by microcoulometry.
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Development of the lipid-rich core in human atherosclerosis.
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Development, validation and application of a comprehensive stereoselective LC/MS-MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine.
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Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver.
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Diethyldithiocarbamate potentiates the effects of protamine sulphate in the isolated rat uterus.
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Differences in O2 availability resolve the apparent discrepancies in metabolic intrinsic optical signals in vivo and in vitro.
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Differences in brain cytochrome responses to carbon monoxide and cyanide in vivo.
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Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.
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Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis.
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Differential localization and potency of manganese porphyrin superoxide dismutase-mimicking compounds in Saccharomyces cerevisiae.
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Differential sympathetic neural control of oxygenation in resting and exercising human skeletal muscle.
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Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion.
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Direct antidiabetic effect of leptin through triglyceride depletion of tissues.
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Direct effects of CO on cerebral energy metabolism in bloodless rats.
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Direct evaluation of electronic coupling mediated by hydrogen bonds: implications for biological electron transfer.
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Discordant extracellular superoxide dismutase expression and activity in neonatal hyperoxic lung.
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Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements.
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Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.
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Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG.
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Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics.
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Domain interactions in oxidized and reduced forms of rat liver sulfite oxidase.
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Duodenal cytochrome b: a novel ferrireductase in airway epithelial cells.
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ELEMENTARY STEPS IN ENZYME REACTIONS (AS STUDIED BY RELAXATION SPECTROMETRY).
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ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.
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Early development of near-infrared spectroscopy at Duke University.
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Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans.
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Ecosystem engineers activate mycorrhizal mutualism in salt marshes.
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Editorial overview: Biological pathways for electrons, protons and photo-excitations.
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Effect of acid predissolution on fibril size and fibril flexibility of synthetic beta-amyloid peptide.
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Effect of chemical modification of dihydrouridine in yeast transfer ribonucleic acid on amino acid acceptor activity and ribosomal binding.
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Effect of cystine loading on substrate oxidation by rat renal tubules.
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Effect of gamma irradiation on fatty acid oxidation in rat liver slices.
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Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat.
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Effect of transient hypoxia on oxygenation of the developing rat brain: relationships among haemoglobin saturation, autoregulation of blood flow and mitochondrial redox state.
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Effects of Manganese Porphyrins on Cellular Sulfur Metabolism.
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Effects of age on energy expenditure and substrate oxidation during experimental overfeeding in healthy men.
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Effects of beta-carotene repletion on beta-carotene absorption, lipid peroxidation, and neutrophil superoxide formation in young men.
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Effects of combined supplementation with antioxidants on low-density lipoprotein oxidation.
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Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes.
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Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest.
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Effects of muscle contraction on cytochrome a,a3 redox state.
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Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
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Effects of relative hypoglycemia on LTP and NADH imaging in rat hippocampal slices.
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Electrically conductive "alkylated" graphene paper via chemical reduction of amine-functionalized graphene oxide paper.
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Electrochemical activation of electrodes for amperometric detection of nitric oxide.
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Electrode materials for nitric oxide detection.
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Electron Bifurcation: Thermodynamics and Kinetics of Two-Electron Brokering in Biological Redox Chemistry.
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Electron paramagnetic resonance and optical evidence for interaction between siroheme and Fe4S4 prosthetic groups in complexes of Escherichia coli sulfite reductase hemoprotein with added ligands.
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Electron paramagnetic resonance and potentiometric studies of arsenite interaction with the molybdenum centers of xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: a specific stabilization of the molybdenum(V) oxidation state.
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Electron paramagnetic resonance properties and oxidation-reduction potentials of the molybdenum, flavin, and iron-sulfur centers of chicken liver xanthine dehydrogenase.
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Electron transfer in the photosynthetic reaction center: mechanistic implications of mutagenesis studies.
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Electron-Donating Phenolic and Electron-Accepting Quinone Moieties in Peat Dissolved Organic Matter: Quantities and Redox Transformations in the Context of Peat Biogeochemistry.
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Electron-nuclear double resonance studies of oxidized Escherichia coli sulfite reductase: 1H, 14N, and 57Fe measurements.
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Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+.
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Elementary steps in the reaction mechanism of chicken liver fatty acid synthase: reduced nicotinamide adenine dinucleotide phosphate binding and formation and reduction of acetoacetyl-enzyme.
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Elementary steps in the reaction mechanism of pyruvate dehydrogenase multienzyme complex from Escherichia coli: kinetics of flavin reduction.
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Elucidation of a [4Fe-4S] cluster degradation pathway: rapid kinetic studies of the degradation of Chromatium vinosum HiPIP.
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Enantioselective Synthesis of anti-1,2-Diamines by Cu-Catalyzed Reductive Couplings of Azadienes with Aldimines and Ketimines.
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Endothelial superoxide production is altered in sheep programmed by early gestation dexamethasone exposure.
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Energetics-based methods for protein folding and stability measurements.
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Energy Transduction in Nitrogenase.
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Energy metabolism and in vivo cytochrome c oxidase redox relationships in hypoxic rat brain.
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Engineering oxidative stability in human hemoglobin based on the Hb providence (βK82D) mutation and genetic cross-linking.
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Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA.
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Environmental conditions influence the plant functional diversity effect on potential denitrification.
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Enzymatically amplified voltammetric sensor for microliter sample volumes of salicylate.
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Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
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Estrogen-Related Receptor Alpha: An Under-Appreciated Potential Target for the Treatment of Metabolic Diseases.
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Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy.
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Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models.
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Evaluation of the oxidation of organic compounds by aqueous suspensions of photosensitized hydroxylated-C60 fullerene aggregates.
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Evidence for siroheme-Fe4S4 interaction in spinach ferredoxin-sulfite reductase.
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Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle.
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Evolution and biogeography of deep-sea vent and seep invertebrates.
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Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
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Expression of the vaccinia virus A2.5L redox protein is required for virion morphogenesis.
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Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.
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Extreme differences between hemoglobins I and II of the clam Lucina pectinalis in their reactions with nitrite.
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Extremely high levels of NADPH in guinea pig lens: correlation with zeta-crystallin concentration.
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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Factors Controlling the Risks of Co-occurrence of the Redox-Sensitive Elements of Arsenic, Chromium, Vanadium, and Uranium in Groundwater from the Eastern United States.
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Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.
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Fatty acid oxidation abnormalities in childhood-onset spinal muscular atrophy: primary or secondary defect(s)?
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Fatty acid oxidation and insulin action: when less is more.
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Flavin interaction in NADPH-sulfite reductase.
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Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins.
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Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor.
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Fluorescence energy transfer between the thiamine diphosphate and flavine adenine dinucleotide binding sites on the pyruvate dehydrogenase multienzyme complex.
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Free radicals and antioxidants at a glance using EPR spectroscopy.
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Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.
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Full-electron ligand-to-ligand charge transfer in a compact Re(I) complex.
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Functional equivalence of monomeric (shark) and dimeric (bovine) cytochrome c oxidase.
-
Functional evaluation of nonphagocytic NAD(P)H oxidases.
-
Functional heterogeneity of type 1 fimbriae of Escherichia coli.
-
Functional inactivation and structural disruption of human alpha 2-macroglobulin by neutrophils and eosinophils.
-
Functional requirement of a wild-type allele for mutant IDH1 to suppress anchorage-independent growth through redox homeostasis.
-
Functional studies on crosslinked bovine cytochrome c oxidase.
-
Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite.
-
G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.
-
Gamma-L-glutaminyl-3,4-benzoquinone. Structural studies and enzymatic synthesis.
-
Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins.
-
Global analysis of protein folding thermodynamics for disease state characterization.
-
Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell.
-
Glucose metabolism as a target of histone deacetylase inhibitors.
-
Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase.
-
Glutathione and zebrafish: Old assays to address a current issue.
-
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
-
Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation.
-
Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.
-
Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems.
-
Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions.
-
Health effects of a mixture of indoor air volatile organics, their ozone oxidation products, and stress.
-
Heme Oxygenase-1/Carbon Monoxide System and Embryonic Stem Cell Differentiation and Maturation into Cardiomyocytes.
-
Heme proteins and nitric oxide (NO): the neglected, eloquent chemistry in NO redox signaling and regulation.
-
Heme redox properties of S-nitrosated hemoglobin A0 and hemoglobin S: implications for interactions of nitric oxide with normal and sickle red blood cells.
-
Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide.
-
Hemoglobin Abruzzo (beta143 (H21) His replaced by Arg). Consequences of altering the 2,3-diphosphoglycerate binding site.
-
Hemoglobin-based oxygen carriers (HBOCs): structural alterations that affect free radical generation.
-
Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism.
-
Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity.
-
Hepatic sulfite oxidase. Identification of the molybdenum center as the site of irreversible inactivation by ferricyanide.
-
Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription.
-
High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli.
-
Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.
-
Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity.
-
How can a single second sphere amino acid substitution cause reduction midpoint potential changes of hundreds of millivolts?
-
Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate.
-
Human halothane reduction in vitro by cytochrome P450 2A6 and 3A4: identification of low and high KM isoforms.
-
Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis.
-
Hydrogen sulphide enhances photosynthesis through promoting chloroplast biogenesis, photosynthetic enzyme expression, and thiol redox modification in Spinacia oleracea seedlings.
-
Hypothesis: iron chelation plays a vital role in neutrophilic inflammation.
-
Hypothesis: is lung disease after silicate inhalation caused by oxidant generation?
-
Identification and quantification of regioisomeric cholesteryl linoleate hydroperoxides in oxidized human low density lipoprotein and high density lipoprotein.
-
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases.
-
Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates.
-
Identification of hydroxyl radical oxidation products of N-hexanoyl-homoserine lactone by reversed-phase high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
-
Identification of in vitro rat metabolites of 1-phenylcyclohexene.
-
Identification of the iron-sulfur center of spinach ferredoxin-nitrite reductase as a tetranuclear center, and preliminary EPR studies of mechanism.
-
Immunoreactivity of apolipoprotein B-100 in oxidatively modified low density lipoprotein.
-
Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.
-
Impaired systemic tetrahydrobiopterin bioavailability and increased oxidized biopterins in pediatric falciparum malaria: association with disease severity.
-
Important cellular targets for antimicrobial photodynamic therapy.
-
Improved blackwater disinfection using potentiodynamic methods with oxidized boron-doped diamond electrodes.
-
In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction.
-
In vitro reconstitution of demolybdosulfite oxidase by molybdate.
-
In vivo modulation of norepinephrine-induced cerebral oxygenation states by hypoxia and hyperoxia.
-
In vivo repair of alkylating and oxidative DNA damage in the mitochondrial and nuclear genomes of wild-type and glycosylase-deficient Caenorhabditis elegans
-
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.
-
Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression.
-
Inducers of plant systemic acquired resistance regulate NPR1 function through redox changes.
-
Induction of clusterin in acute and chronic oxidative renal disease in the rat and its dissociation from cell injury.
-
Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.
-
Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells.
-
Inhibition of microsomal oxidative drug metabolism by 1,4-bis (2-[(2-hydroxyethyl)amino]-ethylamino)-9,10-anthracenedione diacetate, a new antineoplastic agent.
-
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.
-
Inhibition of the Continuum of Radiation-Induced Normal Tissue Injury by a Redox-Active Mn Porphyrin.
-
Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant.
-
Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.
-
Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism.
-
Interaction of reduced nicotinamide adenine dinucleotide with beef heart s-malate dehydrogenase.
-
Interactions of nicotinamide adenine dinucleotides with varied states and forms of hemoglobin.
-
Interhemispheric synchrony of slow oscillations of cortical blood volume and cytochrome aa3 redox state in unanesthetized rabbits.
-
Internal electron transfer between hemes and Cu(II) bound at cysteine beta93 promotes methemoglobin reduction by carbon monoxide.
-
Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver.
-
Intracellular monitoring of experimental respiratory failure. Collaborative Group on Intracellular Monitoring.
-
Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress.
-
Intramuscular fatty acid metabolism in contracting and non-contracting human skeletal muscle.
-
Intraocular pressure effects on optic nerve-head oxidative metabolism measured in vivo.
-
Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme.
-
Involvement of radical species in the oxidation of aminopyrine and 4-aminoantipyrine by cumene hydroperoxide in rat liver microsomes.
-
Involvement of reactive oxygen species in the electrochemical inhibition of barnacle (Amphibalanus amphitrite) settlement
-
Iron chelation equilibria, redox, and siderophore activity of a saccharide platform ferrichrome analogue.
-
Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase.
-
Isolation from the mushroom Agaricus bisporus and chemical synthesis of gamma-L-glutaminyl-4-hydroxybenzene.
-
Kinetic and nuclear magnetic resonance study of the interaction of NADP+ and NADPH with chicken liver fatty acid synthase.
-
Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines.
-
Kinetics of allosteric enzymes.
-
Kinetics of reduction of cytochrome c oxidase by dithionite and the effect of hydrogen peroxide.
-
L-glutamine supplementation of a high fat diet reduces body weight and attenuates hyperglycemia and hyperinsulinemia in C57BL/6J mice.
-
LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease.
-
Large Cellular Inclusions Accumulate in Arabidopsis Roots Exposed to Low-Sulfur Conditions.
-
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX.
-
Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice.
-
Leucine metabolism during fasting and exercise.
-
Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens.
-
Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: Progress and Considerations for Mitochondrial Adverse Outcome Pathways.
-
Lipid membrane immobilized horseradish peroxidase biosensor for amperometric determination of hydrogen peroxide.
-
Lipid-induced metabolic dysfunction in skeletal muscle.
-
Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation.
-
Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.
-
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition.
-
Living related versus deceased donor liver transplantation for maple syrup urine disease.
-
Long-Term Transformation and Fate of Manufactured Ag Nanoparticles in a Simulated Large Scale Freshwater Emergent Wetland.
-
Long-chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation.
-
Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.
-
Longitudinal optical imaging of tumor metabolism and hemodynamics.
-
Los Angeles student nurse study. Daily symptom reporting and photochemical oxidants.
-
Low-frequency oscillations of cortical oxidative metabolism in waking and sleep.
-
Lucigenin: redox potential in aqueous media and redox cycling with O-(2) production.
-
MIBG inhibits respiration: potential for radio- and hyperthermic sensitization.
-
Magnetic interactions in milk xanthine oxidase.
-
Magnetization of the sulfite and nitrite complexes of oxidized sulfite and nitrite reductases: EPR silent spin S = 1/2 states.
-
Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells.
-
Manganese Porphyrin and Radiotherapy Improves Local Tumor Response and Overall Survival in Orthotopic Murine Mammary Carcinoma Models.
-
Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite.
-
Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells.
-
Manganese porphyrins and related compounds as mimics of superoxide dismutase.
-
Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple.
-
Manganese-based superoxide dismutase mimics modify both acute and long-term outcome severity in a Drosophila melanogaster model of classic galactosemia.
-
Manganese-porphyrin reactions with lipids and lipoproteins.
-
Mapping hole hopping escape routes in proteins.
-
Mapping of peroxyl radical induced damage on genomic DNA.
-
Mapping oxidative DNA damage at nucleotide level.
-
Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology.
-
Mapping staphylococcal nuclease conformation using an EDTA-Fe derivative attached to genetically engineered cysteine residues.
-
Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.
-
Measurement of fatty acid oxidation rates in animal tissues and cell lines.
-
Measurements of secondary organic aerosol from oxidation of cycloalkenes, terpenes, and m-xylene using an Aerodyne aerosol mass spectrometer.
-
Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin.
-
Mechanisms of disease progression in nonalcoholic fatty liver disease.
-
Mechanisms of inactivation of molybdoenzymes by cyanide.
-
Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells.
-
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.
-
Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging.
-
Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio.
-
Metabolic regulation of Akt: roles reversed.
-
Metabolism of levulinate in perfused rat livers and live rats: conversion to the drug of abuse 4-hydroxypentanoate.
-
Metabolism of norethynodrel by rat liver.
-
Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure.
-
Metabolomic analysis reveals altered skeletal muscle amino acid and fatty acid handling in obese humans.
-
Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet.
-
Metabolomics evaluation of early-storage red blood cell rejuvenation at 4°C and 37°C.
-
Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.
-
Metalloporphyrins are potent inhibitors of lipid peroxidation.
-
Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders.
-
Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase.
-
Methionine metabolism in health and cancer: a nexus of diet and precision medicine.
-
Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I).
-
Methionine oxidation of monomeric lambda repressor: the denatured state ensemble under nondenaturing conditions.
-
Methionine sulfoxide and the oxidative regulation of plasma proteinase inhibitors.
-
Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia.
-
Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.
-
Microbial hydroxylation and reduction of the diterpene psiadin.
-
Mitochondrial Dysfunction: Metabolic Drivers of Pulmonary Hypertension.
-
Mitochondrial NADH as the bellwether of tissue O2 delivery.
-
Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma.
-
Mitochondrial adaptations to obesity-related oxidant stress.
-
Mitochondrial dysfunction and insulin resistance: a matter of lifestyle?
-
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
-
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.
-
Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.
-
Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1.
-
Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury.
-
Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death.
-
Modular isotopomer synthesis of γ-hydroxybutyric acid for a quantitative analysis of metabolic fates.
-
Modulation of cytotoxicity of menadione sodium bisulfite versus leukemia L1210 by the acid-soluble thiol pool.
-
Molecular basis of the biological function of molybdenum. Molybdenum-free sulfite oxidase from livers of tungsten-treated rats.
-
Molecular basis of the biological function of molybdenum. Molybdenum-free xanthine oxidase from livers of tungsten-treated rats.
-
Molecular controls of the oxygenation and redox reactions of hemoglobin.
-
Molybdopterin in carbon monoxide oxidase from carboxydotrophic bacteria.
-
Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy.
-
Muscle reoxygenation rate after isometric exercise at various intensities in relation to muscle oxidative capacity.
-
Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction.
-
Mutation of potassium permanganate- and hydrogen peroxide-treated plasmid pZ189 replicating in CV-1 monkey kidney cells.
-
Mössbauer evidence for exchange-coupled siroheme and [4Fe-4S] prosthetic groups in Escherichia coli sulfite reductase. Studies of the reduced states and of a nitrite turnover complex.
-
Mössbauer spectroscopic studies of Escherichia coli sulfite reductase. Evidence for coupling between the siroheme and Fe4S4 cluster prosthetic groups.
-
N-Heterocyclic carbene catalyzed oxidative macrolactonization: total synthesis of (+)-dactylolide.
-
NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans.
-
NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia.
-
NADH fluorescence and [K+]o changes during hippocampal electrical stimulation.
-
NADH hyperoxidation correlates with enhanced susceptibility of aged rats to hypoxia.
-
NADPH oxidase 4: walking the walk with Poldip2.
-
NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.
-
NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism.
-
Nanotechnologies: tools for sustainability in a new wave of water treatment processes.
-
Near infrared spectroscopy: in situ studies of skeletal and cardiac muscle.
-
Near-infrared excited state dynamics of melanins: the effects of iron content, photo-damage, chemical oxidation, and aggregate size.
-
Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity.
-
Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier.
-
Neutrophil elastase induces MUC5AC messenger RNA expression by an oxidant-dependent mechanism.
-
New approach to the activation of anti-cancer pro-drugs by metalloporphyrin-based cytochrome P450 mimics in all-aqueous biologically relevant system.
-
New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins.
-
New insights into the proton-dependent oxygen affinity of Root effect haemoglobins.
-
Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.
-
Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes.
-
Nitric oxide and differential effects of ATP on mitochondrial permeability transition.
-
Nitric oxide and redox mechanisms in the immune response.
-
Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in hepatitis.
-
Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.
-
Nitric oxide binding to human ferrihemoglobins cross-linked between either alpha or beta subunits.
-
Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation.
-
Nitric-oxide synthase output state. Design and properties of nitric-oxide synthase oxygenase/FMN domain constructs.
-
Nitrofurantoin-stimulated superoxide production by channel catfish (Ictalurus punctatus) hepatic microsomal and soluble fractions.
-
Nitrosation and oxidation in the regulation of gene expression.
-
Nonequivalence of the flavin adenine dinucleotide moieties of chicken liver xanthine dehydrogenase.
-
Noninvasive monitoring of cerebral oxygenation in preterm infants: preliminary observations.
-
Normal skeletal muscle Na(+)-K(+) pump concentration in patients with chronic heart failure.
-
Novel Integrated Biotrickling Filter-Anammox Bioreactor System for the Complete Treatment of Ammonia in Air with Nitrification and Denitrification.
-
Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling.
-
Nox4 NADPH oxidase: emerging from the veil of darkness.
-
Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.
-
Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice.
-
O2 dependence of in vivo brain cytochrome redox responses and energy metabolism in bloodless rats.
-
Obesity, Immunity, and Cancer.
-
Odor and volatile organic compound treatment by biotrickling filters: pilot-scale studies at hyperion treatment plant.
-
On the polyol synthesis of silver nanostructures: glycolaldehyde as a reducing agent.
-
On the reaction of ferric heme proteins with nitrite and sulfite.
-
Operational aspects of the desulfurization process of energy gases mimics in biotrickling filters.
-
Opioid use affects antioxidant activity and purine metabolism: preliminary results.
-
Organ protective mechanisms common to extremes of physiology: a window through hibernation biology.
-
Ortho Isomeric Mn(III) N-Alkyl- and Alkoxyalkylpyridylporphyrins-Enhancers of Hyaluronan Degradation Induced by Ascorbate and Cupric Ions.
-
Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.
-
Orthogonal site-specific protein modification by engineering reversible thiol protection mechanisms.
-
Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats.
-
Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity.
-
Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.
-
Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury.
-
Oxalate deposition on asbestos bodies.
-
Oxidant generation promotes iron sequestration in BEAS-2B cells exposed to asbestos.
-
Oxidation Potentials of Human Eumelanosomes and Pheomelanosomes
-
Oxidation of Reduced Peat Particulate Organic Matter by Dissolved Oxygen: Quantification of Apparent Rate Constants in the Field.
-
Oxidation of molybdopterin in sulfite oxidase by ferricyanide. Effect on electron transfer activities.
-
Oxidation of phenazine methosulfate by hepatic aldehyde oxidase.
-
Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding.
-
Oxidation-reduction potentials of molybdenum, flavin, and iron-sulfur centers in milk xanthine oxidase: variation with pH.
-
Oxidations in kidney mitochondria of heat-exposed rats: regulation by cytochrome c.
-
Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin.
-
Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high-dose infusional doxorubicin.
-
Oxidative DNA damage during night shift work.
-
Oxidative DNA damage during sleep periods among nightshift workers.
-
Oxidative activities in mitochondria-like particles from Setaria digitata, a filarial parasite.
-
Oxidative and nonoxidative macronutrient disposal in lean and obese men after mixed meals.
-
Oxidative dissociation of human alpha 2-macroglobulin tetramers into dysfunctional dimers.
-
Oxidative iron species and ocean challenges: a perspective.
-
Oxidative metabolism during recurrent seizures in the penicillin treated hippocampus.
-
Oxidative metabolism in rat hepatocytes and mitochondria during sepsis.
-
Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice.
-
Oxidative stress activates anion exchange protein 2 and AP-1 in airway epithelial cells.
-
Oxidative stress and neurobehavioral problems in pediatric acute lymphoblastic leukemia patients undergoing chemotherapy.
-
Oxidative stress-induced expression and modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in mammalian retina.
-
Oxidatively modified proteins as plasma biomarkers in breast cancer.
-
Oxidized alpha2-macroglobulin (alpha2M) differentially regulates receptor binding by cytokines/growth factors: implications for tissue injury and repair mechanisms in inflammation.
-
Oxidized dimeric Scapharca inaequivalvis. Co-driven perturbation of the redox equilibrium.
-
Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells.
-
Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism.
-
Oxygen binding to partially nitrosylated hemoglobin.
-
Oxygen flux analysis to understand the biological function of sirtuins.
-
Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2.
-
Oxygen-containing functional groups on single-wall carbon nanotubes: NEXAFS and vibrational spectroscopic studies
-
Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.
-
Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study.
-
PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.
-
PPAR alpha ligand protects during cisplatin-induced acute renal failure by preventing inhibition of renal FAO and PDC activity.
-
Painting proteins with covalent labels: what's in the picture?
-
Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE).
-
Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation.
-
Pathways of folding of reduced bovine pancreatic ribonuclease.
-
Perchlorate reduction by autotrophic bacteria attached to zerovalent iron in a flow-through reactor.
-
Perchlorate reduction by autotrophic bacteria in the presence of zero-valent iron.
-
Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter.
-
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals.
-
Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid.
-
Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins.
-
Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites.
-
Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice.
-
Photochemical energy conversion in a helical oligoproline assembly.
-
Photoinduced electron transfer between the Rieske iron-sulfur protein and cytochrome c(1) in the Rhodobacter sphaeroides cytochrome bc(1) complex. Effects of pH, temperature, and driving force.
-
Phototoxicity in human retinal pigment epithelial cells promoted by hypericin, a component of St. John's wort.
-
Physical constraints on charge transport through bacterial nanowires.
-
Pigment formation from L-tryptophan by a particulate fraction from an Achromobacter species.
-
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
-
Plant Immunity Requires Conformational Changes of NPR1 via S-Nitrosylation and Thioredoxins
-
Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men.
-
Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction.
-
Platelet mitochondrial complex I and I+III activities do not correlate with cerebral mitochondrial oxidative metabolism.
-
Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells.
-
Polyethylene glycol modification of serpins improves therapeutic potential.
-
Polysaccharide elasticity governed by chair-boat transitions of the glucopyranose ring.
-
Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins In Vivo.
-
Post-illumination cellular effects of photodynamic treatment.
-
Potential impacts of leakage from deep CO2 geosequestration on overlying freshwater aquifers.
-
Potentiometric, electronic structural, and ground- and excited-state optical properties of conjugated bis[(porphinato)zinc(II)] compounds featuring proquinoidal spacer units.
-
Preparation and characterization of fouling-resistant photocatalytic metal membrane embedded with self-organized TiO₂ nano tube.
-
Prevention of H2O2 generation by monoamine oxidase protects against CNS O2 toxicity.
-
Pro-oxidant status and Nrf2 levels in psoriasis vulgaris skin tissues and dimethyl fumarate-treated HaCaT cells.
-
Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products.
-
Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease.
-
Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress.
-
Properties of the prosthetic groups of rabbit liver aldehyde oxidase: a comparison of molybdenum hydroxylase enzymes.
-
Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine.
-
Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells.
-
Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults.
-
Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide.
-
Protein S-nitrosylation: purview and parameters.
-
Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction.
-
Protein phosphorylation and intermolecular electron transfer: a joint experimental and computational study of a hormone biosynthesis pathway.
-
Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer.
-
Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation.
-
Proteomic identification of specific oxidized proteins in ApoE-knockout mice: relevance to Alzheimer's disease.
-
Proton NMR of Escherichia coli sulfite reductase: studies of the heme protein subunit with added ligands.
-
Purification and properties of chicken liver xanthine dehydrogenase.
-
Purification and properties of xanthine dehydroganase from Micrococcus lactilyticus.
-
Purification of a naturally produced, low molecular weight organic factor that reversibly blocks encystment of Blastocladiella emersonii zoospores.
-
Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit.
-
Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes.
-
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.
-
Quantum Mechanics/Molecular Mechanics Method Combined with Hybrid All-Atom and Coarse-Grained Model: Theory and Application on Redox Potential Calculations.
-
Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate.
-
Reaction of N-acylhomoserine lactones with hydroxyl radicals: rates, products, and effects on signaling activity.
-
Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.
-
Recovery of cerebral metabolism and mitochondrial oxidation state is delayed after hypothermic circulatory arrest.
-
Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability.
-
Redox Activation of Nox1 (NADPH Oxidase 1) Involves an Intermolecular Disulfide Bond Between Protein Disulfide Isomerase and p47phox in Vascular Smooth Muscle Cells.
-
Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction.
-
Redox and the circadian clock in plant immunity: A balancing act.
-
Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution.
-
Redox potential determines the reaction mechanism of HNO donors with Mn and Fe porphyrins: defining the better traps.
-
Redox potentials of Ti(IV) and Fe(III) complexes provide insights into titanium biodistribution mechanisms.
-
Redox properties of cytochrome oxidase and vascular reactivity of astrocytomas and neuroblastomas in vivo.
-
Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin.
-
Redox properties of human transferrin bound to its receptor.
-
Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment.
-
Redox redux.
-
Redox regulation of mitochondrial biogenesis.
-
Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis.
-
Redox regulation of neuronal migration in a Down Syndrome model.
-
Redox regulation of the rat hepatocyte iNOS promoter.
-
Redox rhythm reinforces the circadian clock to gate immune response
-
Redox-Active Drug, MnTE-2-PyP5+, Prevents and Treats Cardiac Arrhythmias Preserving Heart Contractile Function.
-
Redox-mediated upregulation of hepatocyte iNOS transcription requires coactivator PC4.
-
Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes.
-
Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. 3. The Escherichia coli hemoflavoprotein: catalytic parameters and the sequence of electron flow.
-
Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. IV. The Escherichia coli hemoflavoprotein: subunit structure and dissociation into hemoprotein and flavoprotein components.
-
Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. VI. The reaction of carbon monoxide with the Escherichia coli holoenzyme, the hemoprotein, and free siroheme.
-
Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling.
-
Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite.
-
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
-
Regulation of mitochondrial biogenesis and its intersection with inflammatory responses.
-
Regulation of mitochondrial processes by protein S-nitrosylation.
-
Relation between the redox state of iron-based nanoparticles and their cytotoxicity toward Escherichia coli.
-
Relationship between dietary retinol and lipofuscin in the retinal pigment epithelium.
-
Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles.
-
Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions.
-
Remote oxidation of steroids by photolysis of attached benzophenone groups.
-
Resonance Raman studies of Escherichia coli sulfite reductase hemoprotein. 1. Siroheme vibrational modes.
-
Resonance Raman studies of Escherichia coli sulfite reductase hemoprotein. 3. Bound ligand vibrational modes.
-
Respiratory Capacity and Reserve Predict Cell Sensitivity to Mitochondria Inhibitors: Mechanism-Based Markers to Identify Metformin-Responsive Cancers.
-
Response to 'Antinuclear antibodies by indirect immunofluorescence and solid phase assays' by Bossuyt et al.
-
Response to: 'ANA testing in "real life"' by Infantino etal.
-
Response to: 'Antinuclear antibody as entry criterion for classification of systemic lupus erythematosus: pitfalls and opportunities' by Bossuyt et al.
-
Responses of normal and sickle cell hemoglobin to S-nitroscysteine: implications for therapeutic applications of NO in treatment of sickle cell disease.
-
Restriction of big hearts by a small RNA.
-
Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells.
-
Reversal of carbon monoxide-cytochrome c oxidase binding by hyperbaric oxygen in vivo.
-
Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).
-
Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases.
-
Role of conserved tyrosine 343 in intramolecular electron transfer in human sulfite oxidase.
-
Role of flavin-containing monooxygenase in oxidative metabolism of voriconazole by human liver microsomes.
-
Role of nucleobase energetics and nucleobase interactions in single-stranded peptide nucleic acid charge transfer.
-
S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system.
-
S-nitrosylation in health and disease.
-
S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
-
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.
-
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
-
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.
-
SOD enzymes and their mimics in cancer: pro vs anti-odixative mode of action-part II.
-
SOD enzymes and their mimics in cancer: pro vs anti-oxidative mode of action. Part I.
-
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways.
-
Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.
-
Scale-up and cost evaluation of a foamed emulsion bioreactor.
-
Selenium speciation in coal ash spilled at the Tennessee Valley Authority Kingston site.
-
Selenium toxicity: cause and effects in aquatic birds.
-
Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection.
-
Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2.
-
Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity.
-
Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism.
-
Serine, glycine and one-carbon units: cancer metabolism in full circle.
-
Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.
-
Short-chain acyl-coenzyme A dehydrogenase deficiency in mice.
-
Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects.
-
Similarities between inorganic sulfide and the strong Hg(II)-complexing ligands in municipal wastewater effluent.
-
Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices.
-
Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults.
-
Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.
-
Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
-
Sirtuin 5 is required for mouse survival in response to cardiac pressure overload.
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.
-
Site-specific incorporation of 3-nitrotyrosine as a probe of pKa perturbation of redox-active tyrosines in ribonucleotide reductase.
-
Size-dependence of surface plasmon resonance and oxidation for Pd nanocubes synthesized via a seed etching process.
-
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization.
-
Skeletal muscle oxygen availability during respiratory acid-base disturbances in cats.
-
Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles.
-
Soft-lithographic approach to functionalization and nanopatterning oxide-free silicon.
-
Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation.
-
Spectroelectrochemistry of heme proteins: effects of active-site heterogeneity on Nernst plots.
-
Spectrophotometry of b-type cytochromes in rat brain in vivo and in vitro.
-
Spectroscopic studies of the molybdenum-containing dimethyl sulfoxide reductase from Rhodobacter sphaeroides f. sp. denitrificans.
-
Stability of Metal-Glutathione Complexes During Oxidation by Hydrogen Peroxide and Cu(II)-Catalysis
-
Stability of oxidized Escherichia coli thioredoxin and its dependence on protonation of the aspartic acid residue in the 26 position.
-
Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.
-
Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation.
-
Stereochemistry of the reactions catalyzed by chicken liver fatty acid synthase.
-
Stereoselective synthesis of 2,6-cis-tetrahydropyrans through a tandem allylic oxidation/oxa-Michael reaction promoted by the gem-disubstituent effect: synthesis of (+)-neopeltolide macrolactone.
-
Stereoselective synthesis of tetrahydrofuran lignans via BF(3) x OEt(2)-promoted reductive deoxygenation/epimerization of cyclic hemiketal: synthesis of (-)-odoratisol C, (-)-futokadsurin A, (-)-veraguensin, (+)-fragransin A(2), (+)-galbelgin, and (+)-talaumidin.
-
Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins.
-
Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A.
-
Strain variation in composition and molecular size of the capsular polysaccharide of Cryptococcus neoformans serotype A.
-
Structural and functional properties of cytochrome c oxidases isolated from sharks.
-
Structural and metabolic relationship between the molybdenum cofactor and urothione.
-
Structural and pH dependence of excited state PCET reactions involving reductive quenching of the MLCT excited state of [RuII(bpy)2(bpz)]2+ by hydroquinones.
-
Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex.
-
Structural characterization of a molybdopterin precursor.
-
Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR.
-
Structure and Affinity of Cu(I) Bound to Human Serum Albumin.
-
Structure and mechanism of copper, zinc superoxide dismutase.
-
Structure, function, and assembly in the hemocyanin system of the scorpion, Androctonus australis.
-
Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
-
Structures of the siroheme- and Fe4S4-containing active center of sulfite reductase in different states of oxidation: heme activation via reduction-gated exogenous ligand exchange.
-
Studies of the copper and heme cofactors of pseudomonad L-tryptophan-2,3-dioxygenase by electron paramagnetic resonance spectroscopy.
-
Studies on the preparation of chitosan microcarriers cross-linked by oxidized lactose and culture of primary hepatocytes.
-
Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism.
-
Subunit structure of fragment D from fibrinogen and cross-linked fibrin.
-
Sulfite reductase structure at 1.6 A: evolution and catalysis for reduction of inorganic anions.
-
Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A).
-
Sulfoxide-containing aromatic nitrogen mustards as hypoxia-directed bioreductive cytotoxins.
-
Supercritical water oxidation of a model fecal sludge without the use of a co-fuel.
-
Superoxide-dependent iron uptake: a new role for anion exchange protein 2.
-
Superoxidized states of Escherichia coli sulfite reductase heme protein subunit.
-
Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.
-
Syncatalytic modification of chicken liver xanthine dehydrogenase by hydrogen peroxide. The nature of the reaction.
-
Synergistic cytotoxicity between menadione and dicumarol vs. murine leukemia L1210.
-
Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing.
-
Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin.
-
Synthesis of oxidation-resistant cupronickel nanowires for transparent conducting nanowire networks.
-
Synthesis of α,α'-trans-oxepanes through an organocatalytic oxa-conjugate addition reaction.
-
Systemic markers of oxidative status and colorectal adenomatous polyps.
-
T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups.
-
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
-
TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.
-
TXNIP links redox circuitry to glucose control.
-
Targeted Mass Spectrometry-Based Approach for Protein-Ligand Binding Analyses in Complex Biological Mixtures Using a Phenacyl Bromide Modification Strategy.
-
Targeted Nrf2 activation therapy with RTA 408 enhances regenerative capacity of diabetic wounds.
-
Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle.
-
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
-
Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs.
-
Ternary complex formation facilitates a redox mechanism for iron release from a siderophore.
-
Tetrahydrobiopterin rapidly reduces the SOD mimic Mn(III) ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin.
-
The Development of a Xenograft-Derived Scaffold for Tendon and Ligament Reconstruction Using a Decellularization and Oxidation Protocol.
-
The Effect of sex steroid hormones on substrate oxidation during prolonged submaximal exercise in women.
-
The Environmental Impacts of the Coal Ash Spill in Kingston, Tennessee: An Eighteen-Month Survey
-
The Roles of β-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana.
-
The arterial wall and the atherosclerotic lesion.
-
The binding of receptor-recognized alpha2-macroglobulin to the low density lipoprotein receptor-related protein and the alpha2M signaling receptor is decoupled by oxidation.
-
The case of the missing NO-hemoglobin: spectral changes suggestive of heme redox reactions reflect changes in NO-heme geometry.
-
The consequences of enhanced cell-autonomous glucose metabolism.
-
The decomposition of thionitrites.
-
The effect of an EDTA-based chelation regimen on patients with diabetes mellitus and prior myocardial infarction in the Trial to Assess Chelation Therapy (TACT).
-
The effect of detergents on the reduction of tetrazolium salts.
-
The effect of plasmin on the subunit structure of human fibrin.
-
The effects of biochar and redox conditions on soil Pb bioaccessibility to people and waterfowl.
-
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.
-
The final touches make perfect the peptide-MHC class I repertoire.
-
The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment.
-
The interaction of biological and noxious transition metals with the zinc probes FluoZin-3 and Newport Green.
-
The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.
-
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
-
The mechanisms of inactivation of sulfite oxidase by periodate and arsenite.
-
The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling.
-
The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic.
-
The oxidation of sulphite in animals systems.
-
The oxidative environment: a mediator of interspecies communication that drives symbiosis evolution.
-
The oxidative stress response.
-
The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF
-
The potential physiological implications of polygalacturonic acid-mediated production of superoxide.
-
The preparation of 3-alpha- and 3-beta,17-beta-Dihydroxy-17-alpha-ethynyl-estr-5(10)-ene.
-
The pterin of the molybdenum cofactor.
-
The redox hypothesis in siderophore-mediated iron uptake.
-
The release of iron from different asbestos structures by hydrogen peroxide with concomitant O2 generation.
-
The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases.
-
The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells.
-
The role of tandem mass spectrometry in the diagnosis of fatty acid oxidation disorders.
-
The role of the supernumerary subunit of Rhodobacter sphaeroides cytochrome bc1 complex.
-
The site of the redox-linked proton pump in eukaryotic cytochrome c oxidases.
-
The state of reduction of molybdopterin in xanthine oxidase and sulfite oxidase.
-
The subunit structures of human plasma and platelet factor XIII (fibrin-stabilizing factor).
-
The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface.
-
The surface oxidation potential of melanosomes measured by free electron laser-photoelectron emission microscopy.
-
The synthesis and secretion of gamma-globulin by lymph node cells. V. The dissociation of the microsome-antibody complex with enzymatically and chemically altered gamma-globulins.
-
The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
-
The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.
-
Theoretical study of catalytic mechanism for single-site water oxidation process.
-
Thermal Activation of Peracetic Acid in Aquatic Solution: The Mechanism and Application to Degrade Sulfamethoxazole.
-
Thermal responsive microgels as recyclable carriers to immobilize active proteins with enhanced nonaqueous biocatalytic performance.
-
Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+).
-
Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy.
-
Thermodynamic analysis of protein-ligand binding interactions in complex biological mixtures using the stability of proteins from rates of oxidation.
-
Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach.
-
Thermodynamic effects of reduction of the active-site disulfide of Escherichia coli thioredoxin explored by differential scanning calorimetry.
-
Thermodynamic limits to the ATP/site stoichiometries of oxidative phosphorylation by rat liver mitochondria.
-
Thermodynamics of oxidation-reduction reactions in mammalian nitric-oxide synthase isoforms.
-
Thermogenesis in Adipose Tissue Activated by Thyroid Hormone.
-
Thiol regulation by Mn porphyrins, commonly known as SOD mimics.
-
Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation.
-
Three Pyrimidine Decarboxylations in the Absence of a Catalyst.
-
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
-
TiO2
Nanoparticle-Induced Oxidation of the Plasma Membrane: Importance of the Protein Corona.
-
Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model.
-
To oxidize or not to oxidize?
-
Total synthesis of cyanolide A and confirmation of its absolute configuration.
-
Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants.
-
Transitions from functionalization to fragmentation reactions of laboratory secondary organic aerosol (SOA) generated from the OH oxidation of alkane precursors.
-
Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo.
-
Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice.
-
Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders: a double blinded, randomized controlled trial.
-
TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response.
-
Tyrosine cross-linking reveals interfacial dynamics in adeno-associated viral capsids during infection.
-
UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation.
-
Understanding the role of oxidative etching in the polyol synthesis of Pd nanoparticles with uniform shape and size.
-
Universal antibiotic tolerance arising from antibiotic-triggered accumulation of pyocyanin in Pseudomonas aeruginosa.
-
Urinary F2-isoprostanes and metabolic markers of fat oxidation.
-
Urinary biomarkers of oxidative status.
-
Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1.
-
Using N-Terminal Coordination of Cu(II) and Ni(II) to Isolate the Coordination Environment of Cu(I) and Cu(II) Bound to His13 and His14 in Amyloid-β(4-16).
-
What if cell culture media do not mimic in vivo redox settings?
-
Why Do Most Aromatics Fail to Support Hole Hopping in the Cytochrome c
Peroxidase-Cytochrome c
Complex?
-
Yeast base excision repair: interconnections and networks.
-
alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation.
-
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
-
cis-dichlorodiammineplatinum (II) as a selective modifier of the oxidation-sensitive reactive-center methionine in alpha 1-antitrypsin.
-
l-citrulline prevents asymmetric dimethylarginine-mediated reductions in nitric oxide and nitrosative stress in primary human airway epithelial cells.
-
α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide.
-
α-synucleinopathy exerts sex-dimorphic effects on the multipurpose DNA repair/redox protein APE1 in mice and humans.
-
Keywords of People
-
-
Beratan, David N.,
R.J. Reynolds Distinguished Professor of Chemistry,
Nicholas Institute-Energy Initiative
-
Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
-
Freemark, Michael Scott,
Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine,
Pediatrics, Endocrinology
-
Hirschey, Matthew,
Associate Professor of Medicine,
Cell Biology
-
Hsu-Kim, Heileen,
Professor in the Department of Civil and Environmental Engineering,
Civil and Environmental Engineering
-
McDonnell, Donald Patrick,
Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine,
Cell Biology
-
Turner, Dennis Alan,
Professor of Neurosurgery,
Biomedical Engineering