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Subject Areas on Research
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"Click" reactions: a versatile toolbox for the synthesis of peptide-conjugates.
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3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model.
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60-kDa Ro protein autoepitopes identified using recombinant polypeptides.
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A CDC6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor.
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A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens.
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A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination.
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A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics.
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A Therapeutic Antibody for Cancer, Derived from Single Human B Cells.
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A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation.
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A chemotactic factor for mononuclear leukocytes.
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A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.
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A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope.
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A continuous fluorometric assay for the feline immunodeficiency virus protease.
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A cross sectional analysis of 5 different markers of collagen degradation in rheumatoid arthritis.
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A crystal structure of a dimer of the antibiotic ramoplanin illustrates membrane positioning and a potential Lipid II docking interface.
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A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation.
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A mastoparan-derived peptide has broad-spectrum antiviral activity against enveloped viruses.
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A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom.
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A metabolic signature of colon cancer initiating cells.
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A molecular defect in two families with hemolytic poikilocytic anemia: reduction of high affinity membrane binding sites for ankyrin.
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A molecular dynamics simulation of the stability-limited growth mechanism of peptide-mediated gold-nanoparticle synthesis.
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A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization.
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A novel method to assess platelet inhibition by eptifibatide with thrombelastograph.
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A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO.
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A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models.
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A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.
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A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy.
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A peptide sequence on carcinoembryonic antigen binds to a 80kD protein on Kupffer cells.
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A phase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss from high-risk cardiac surgery with cardiopulmonary bypass (CONSERV-2 Trial).
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A phase III, randomized, double-blind, placebo-controlled, study of iseganan for the reduction of stomatitis in patients receiving stomatotoxic chemotherapy.
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A potential therapeutic application of SET/I2PP2A inhibitor OP449 for canine T-cell lymphoma.
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A powerful combinatorial screen to identify high-affinity terbium(III)-binding peptides.
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A proteogenomic survey of the Medicago truncatula genome.
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A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles.
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A randomized, placebo-controlled trial of early eptifibatide for non-ST-segment elevation acute coronary syndromes.
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A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.
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A retroviral-derived peptide phosphorylates protein kinase D/protein kinase Cmu involving phospholipase C and protein kinase C.
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A role for GAPDH in apoptosis and neurodegeneration.
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A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.
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A solid sample preparation method that reduces signal suppression effects in the MALDI analysis of peptides.
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A symposium: safety issues concerning the use of glycoprotein IIb-IIIa inhibitors in the management of acute coronary syndromes.
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A synthetic peptide homologous to retroviral envelope protein down-regulates TNF-alpha and IFN-gamma mRNA expression.
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A synthetic peptide homologous to retroviral transmembrane envelope proteins depresses protein kinase C mediated lymphocyte proliferation and directly inactivated protein kinase C: a potential mechanism for immunosuppression.
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A synthetic peptide homologous to the envelope proteins of retroviruses inhibits monocyte-mediated killing by inactivating interleukin 1.
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A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition.
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A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major and minor histocompatibility antigens in vitro and confers the capacity to prevent murine graft-versus-host disease in vivo.
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A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
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A thermally responsive biopolymer for intra-articular drug delivery.
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A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation.
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A truncated progesterone receptor (PR-M) localizes to the mitochondrion and controls cellular respiration.
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A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.
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ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma.
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APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response.
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Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells.
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Accelerated neural differentiation of mouse embryonic stem cells on aligned GYIGSR-functionalized nanofibers.
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Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinase.
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Acentric 2-D ensembles of D-br-A electron-transfer chromophores via vectorial orientation within amphiphilic n-helix bundle peptides for photovoltaic device applications.
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Acquired angioedema in B cell lymphoproliferative disease: A retrospective case series.
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Activation of factor X by factor VIIa on monocyte cell surfaces.
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Activation of interleukin 4- and interleukin 6-secreting cells by HIV-specific synthetic peptides.
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Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV.
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Activation-dependent conformational changes in {beta}-arrestin 2.
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Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.
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Active immunotherapy for TNF-mediated inflammation using self-assembled peptide nanofibers.
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Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia.
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Activin A and follistatin are dynamically regulated during human pregnancy.
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Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs.
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Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage.
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Adrenomedullin expression in rat uterus is correlated with plasma estradiol.
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Adrenomedullin, endothelin, neuropeptide Y, atrial, brain, and C-natriuretic prohormone peptides compared as early heart failure indicators.
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Adverse alterations in bone metabolism are associated with lung infection in adults with cystic fibrosis.
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Agent-based modeling of the context dependency in T cell recognition.
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Aggregation of rabbit muscle phosphofructokinase.
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Aging is not associated with bone marrow-resident progenitor cell depletion.
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Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity.
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Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes.
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Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals.
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Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing.
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Alternative translation initiation site usage results in two structurally distinct forms of Pit-1.
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Alzheimer’s disease: the new promise.
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Ameliorating reperfusion injury in STEMI: dead or alive?
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Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.
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Amino acid sequence requirements of peptides that inhibit polyglutamine-protein aggregation and cell death.
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Amphiphilic four-helix bundle peptides designed for light-induced electron transfer across a soft interface.
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An analysis of type-C retrovirus polypeptides and their associations in the virion.
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An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
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An apolipoprotein E-mimetic stimulates axonal regeneration and remyelination after peripheral nerve injury.
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An array of 60,000 antibodies for proteome-scale antibody generation and target discovery.
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An economical and preparative orthogonal solid phase synthesis of fluorescein and rhodamine derivatized peptides: FRET substrates for the Staphylococcus aureus sortase SrtA transpeptidase reaction.
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An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a.
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An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug.
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An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration.
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Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis.
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Angiographic outcomes with early eptifibatide therapy in non-ST-segment elevation acute coronary syndrome (from the EARLY ACS Trial).
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Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia.
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Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects.
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Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
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Antibodies in sera of patients with late-onset myasthenia gravis recognize the PEVK domain of titin.
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Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
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Antiplatelet and anticoagulation agents in acute coronary syndromes: what is the current status and what does the future hold?
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Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates.
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Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
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Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer.
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Apolipoprotein E and mimetic peptide initiate a calcium-dependent signaling response in macrophages.
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Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis.
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Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease.
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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
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Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity.
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Applications of elastin-like polypeptides in drug delivery.
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Applications of elastin-like polypeptides in tissue engineering.
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Aqueous two-phase system formation kinetics for elastin-like polypeptides of varying chain length
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Assessment of sex steroid action in vitro.
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Association between ankyrin and the cytoplasmic domain of band 3 isolated from the human erythrocyte membrane.
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Association between bleeding and mortality among women and men with high-risk acute coronary syndromes: insights from the Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes (EARLY ACS) trial.
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Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction.
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Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study.
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Association of the timing of ST-segment resolution with TIMI myocardial perfusion grade in acute myocardial infarction.
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Asteropsin A: an unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx.
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Atomic force microscopy captures folded ribosome bound nascent chains.
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Atrial fibrillation and mortality among patients with acute coronary syndromes without ST-segment elevation: results from the PURSUIT trial.
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Atrial natriuretic peptide increases adrenomedullin in the circulation of healthy humans.
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Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein IIb/IIIa inhibition with eptifibatide in patients with acute coronary syndromes: observations from the platelet IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
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Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.
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Autoantibodies to the alpha/beta T-cell receptors in human immunodeficiency virus infection: dysregulation and mimicry.
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Autocatalytic intramolecular isopeptide bond formation in gram-positive bacterial pili: a QM/MM simulation.
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Avidity and Cell Uptake of Integrin-Targeting Polypeptide Micelles is Strongly Shape-Dependent.
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B-MuX: a unique murine C-type virus containing the "env" gene of xenotropic viruses and the "gag" gene of the ecotropic virus.
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BKCa channel inhibitor modulates the tumorigenic ability of hormone-independent breast cancer cells via the Wnt pathway.
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Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity.
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Bailout use of platelet glycoprotein IIb-IIIa inhibition during coronary stent implantation: observations from the ESPRIT trial.
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Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
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Berninamycin. 2. Products of acidic hydrolysis, methanolysis, and acetolysis of berninamycin A1.
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Bilayer interfacial properties modulate the binding of amphipathic peptides.
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Bimodal liquid biopsy for cancer immunotherapy based on peptide engineering and nanoscale analysis.
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Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles.
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Biochemical mass spectrometry: worth the weight?
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Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96.
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Biomedical applications of high-performance liquid chromatography-mass spectrometry with continuous-flow fast atom bombardment.
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Bivalent peptides as PDZ domain ligands.
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Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study.
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Bleeding risk associated with eptifibatide (Integrilin) bridging in thoracic surgery patients.
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Blood Lead, Bone Turnover, and Survival in Amyotrophic Lateral Sclerosis.
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Bombesin increases fetal lung growth and maturation in utero and in organ culture.
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Bombesin may play a role in fetal lung growth and maturation in utero and in lung organ culture.
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Bombesin-like peptides and receptors in normal fetal baboon lung: roles in lung growth and maturation.
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Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ.
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Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours.
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Brain cancer stem cells display preferential sensitivity to Akt inhibition.
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Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin.
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C-terminal deletion of the atrophin-1 protein results in growth retardation but not neurodegeneration in mice.
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CCK and other peptides modulate hypothalamic norepinephrine release in the rat: dependence on hunger or satiety.
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CD10/neutral endopeptidase 24.11 in developing human fetal lung. Patterns of expression and modulation of peptide-mediated proliferation.
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CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest?
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CDK12 Activity-Dependent Phosphorylation Events in Human Cells.
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CFTR: development of high- affinity antibodies and localization in sweat gland.
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COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury.
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Ca(2+)-regulated serine protease associated with the nuclear scaffold.
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Caged protein prenyltransferase substrates: tools for understanding protein prenylation.
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Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans.
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Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides.
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Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides.
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Canine bombesin-like gastrin releasing peptides stimulate gastrin release and acid secretion in the dog.
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Capture and release of proteins on the nanoscale by stimuli-responsive elastin-like polypeptide "switches".
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Capturing the mechanical unfolding pathway of a large protein with coiled-coil probes.
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Carbon extension in peptidylnucleoside biosynthesis by radical SAM enzymes.
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Carbon monoxide binding by simple heme proteins under photodissociating conditions.
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Cardiac overexpression of a G(q) inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH(2)-terminal kinase activity in in vivo pressure overload.
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Caspofungin versus amphotericin B for invasive candidiasis.
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Caspofungin: first approved agent in a new class of antifungals.
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Cathepsin D of rabbit skin: an immunoenzymic study.
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Cathepsin K-sensitive poly(ethylene glycol) hydrogels for degradation in response to bone resorption.
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Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds.
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Cell biology. Enforcing the Greatwall in mitosis.
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Cell migration through defined, synthetic ECM analogs.
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Cell penetration properties of maurocalcine, a natural venom peptide active on the intracellular ryanodine receptor.
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Cell surface polarization during yeast mating.
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Cerebral phaeohyphomycosis in an immunodeficient child treated medically with combination antifungal therapy.
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Cerebroventricular bombesin inhibits gastric acid secretion in dogs.
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Chain stiffness of elastin-like polypeptides.
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Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.
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Characterization of a Radical SAM Oxygenase for the Ether Crosslinking in Darobactin Biosynthesis.
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Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair.
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Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types.
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Characterization of monoclonal antibodies with specificity for DNA and the synthetic polypeptide antigen (T,G)-A-L.
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Characterization of substrate phosphorylation and use of calmodulin mutants to address implications from the enzyme crystal structure of calmodulin-dependent protein kinase I.
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Characterization of the MFalpha pheromone of the human fungal pathogen cryptococcus neoformans.
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Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line.
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Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae.
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Characterization of the secondary structure of calmodulin in complex with a calmodulin-binding domain peptide.
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Characterization of the surface topography and putative tertiary structure of the human CD7 molecule.
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Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery.
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Charting the landscape of tandem BRCT domain-mediated protein interactions.
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Chemo-Selection Strategy for Limited Proteolysis Experiments on the Proteomic Scale.
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Chiral control of electron transmission through molecules.
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Chlamydia protease-like activity factor (CPAF): characterization of proteolysis activity in vitro and development of a nanomolar affinity CPAF zymogen-derived inhibitor.
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Cholecystokinin does not stimulate prosomatostatin-derived peptides in man.
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Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide.
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Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase II trial by the prostate cancer clinical trials consortium.
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Circulating progenitor cells can be reliably identified on the basis of aldehyde dehydrogenase activity.
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Clarifying the Relative Impacts of Vascular and Nerve Injury That Culminate in Erectile Dysfunction in a Pilot Study Using a Rat Model of Prostate Irradiation and a Thrombopoietin Mimetic.
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Clinical and therapeutic profile of patients presenting with acute coronary syndromes who do not have significant coronary artery disease.The Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial Investigators.
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Clinical challenges of platelet glycoprotein IIb/IIIa receptor inhibitor therapy: bleeding, reversal, thrombocytopenia, and retreatment.
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Clinical characteristics predict benefits from eptifibatide therapy during coronary stenting: insights from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy (ESPRIT) trial.
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Clinical outcomes after detection of elevated cardiac enzymes in patients undergoing percutaneous intervention. IMPACT-II Investigators. Integrilin (eptifibatide) to Minimize Platelet Aggregation and Coronary Thrombosis-II.
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Clinical pharmacology of higher dose eptifibatide in percutaneous coronary intervention (the PRIDE study).
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Clinical significance of thrombocytopenia during a non-ST-elevation acute coronary syndrome. The platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial experience.
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Clonal analysis of human anti-V3 monoclonal antibodies selected by a V3 tetramer.
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Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study.
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Co-assembling peptides as defined matrices for endothelial cells.
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Coat proteins and selective protein packaging into transport vesicles.
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Coaxial continuous flow fast atom bombardment in conjunction with tandem mass spectrometry for the analysis of biomolecules.
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Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
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Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction: results of the integrilin and tenecteplase in acute myocardial infarction (INTEGRITI) Phase II Angiographic Trial.
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Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. IMPACT-AMI Investigators.
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Combined antibody-high-performance liquid chromatography approach to assess prohormone processing.
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Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia.
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Combining MALDI-FTMS and bioinformatics for rapid peptidomic comparisons.
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Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations.
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Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors.
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Comparative chemical properties of avian oncornavirus polypeptides.
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Comparative study of α-helical and β-sheet self-assembled peptide nanofiber vaccine platforms: influence of integrated T-cell epitopes.
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Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials).
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Comparison of caspofungin and amphotericin B for invasive candidiasis.
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Comparison of catheterization laboratory initiated abciximab and eptifibatide during percutaneous coronary intervention in acute coronary syndromes (an ACUITY substudy).
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Comparison of one-year outcomes following coronary artery stenting in diabetic versus nondiabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy [ESPRIT] Trial).
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Comparison of one-year outcomes...ESPRIT. Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy.
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Complementary effects of thienopyridine pretreatment and platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention; results from the ESPRIT trial.
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Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophore.
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Concentration-Independent Multivalent Targeting of Cancer Cells by Genetically Encoded Core-Crosslinked Elastin/Resilin-like Polypeptide Micelles.
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Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA.
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Conformational dynamics of amyloid beta-protein assembly probed using intrinsic fluorescence.
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Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin.
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Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice.
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Conserved Structural Motif Identified in Peptides That Bind to Geminivirus Replication Protein Rep.
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Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting.
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Contraindicated medication use in dialysis patients undergoing percutaneous coronary intervention.
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Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection.
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Control of muscle formation by the fusogenic micropeptide myomixer.
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Control of the orientational order and nonlinear optical response of the "push-pull" chromophore RuPZn via specific incorporation into densely packed monolayer ensembles of an amphiphilic four-helix bundle peptide: characterization of the peptide-chromophore complexes.
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Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.
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Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8+
T-Cell Responses.
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Controlled apoptosis by a thermally toggled nanoscale amplifier of cellular uptake.
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Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins.
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Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
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Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1.
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Correlation of expression of bombesin-like peptides and receptors with growth inhibition by an anti-bombesin antibody in small-cell lung cancer cell lines.
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Cost effectiveness in Canada of eptifibatide treatment for acute coronary syndrome patients using PURSUIT subgroup analysis.
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Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes.
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Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides.
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Cross-linking of fibrin by fibrin=stabilizing factor.
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Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen.
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Crustacean peptide and peptide-like pheromones and kairomones.
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Cryopreservation of neurospheres derived from human glioblastoma multiforme.
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Cryptococcus neoformans differential gene expression detected in vitro and in vivo with green fluorescent protein.
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Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries.
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Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.
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Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
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Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
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Current knowledge of the platelet glycoprotein IIb/IIIa receptor antagonists for the treatment of coronary artery disease.
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Cutting edge: CD91-independent cross-presentation of GRP94(gp96)-associated peptides.
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Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate.
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Defining an antigenic epitope on platelet factor 4 associated with heparin-induced thrombocytopenia.
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Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: implications for the initiation of the autoimmune response in multiple sclerosis.
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Delivery of glycoprotein IIb/IIIa inhibitor therapy for percutaneous coronary intervention: why not take the intracoronary highway?
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Demonstration of a chemotactic factor receptor on macrophages.
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Dendritic cells cultured in anti-CD40 antibody-immobilized plates elicit a highly efficient peptide-specific T-cell response.
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Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.
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Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions.
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Design and application of a data-independent precursor and product ion repository.
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Design and characterization of a peptide mimotope of the HIV-1 gp120 bridging sheet.
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Design and methodology of the ESPRIT trial: evaluating a novel dosing regimen of eptifibatide in percutaneous coronary intervention.
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Design of a novel small peptide targeted against a tumor-specific receptor.
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Design of experimental synthetic peptide immunogens for prevention of HIV-1 and HTLV-I retroviral infections.
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Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus.
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Design of protease-resistant peptide ligands for the purification of antibodies from human plasma.
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Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery.
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Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease.
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Design, synthesis, and evaluation of linear and cyclic peptide ligands for PDZ10 of the multi-PDZ domain protein MUPP1.
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Designing effective vaccines for colorectal cancer.
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Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease.
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Detection and characterization of methionine oxidation in peptides by collision-induced dissociation and electron capture dissociation.
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Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase.
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Determination of platelet aggregation inhibition during percutaneous coronary intervention with the platelet function analyzer PFA-100.
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Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion.
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Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic.
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Development of a high-performance liquid chromatography assay and revision of kinetic parameters for the Staphylococcus aureus sortase transpeptidase SrtA.
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Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.
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Development of mammalian serum albumin affinity purification media by peptide phage display.
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Development of peptide antagonists for the androgen receptor using combinatorial peptide phage display.
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Development of peptide antagonists that target estrogen receptor beta-coactivator interactions.
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Development of peptide antagonists that target estrogen receptor-cofactor interactions.
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Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung.
-
Diagnostic value of three tumor markers determined in pleural effusions.
-
Differences among the parenteral platelet glycoprotein IIb/IIIa inhibitors and implications for treatment.
-
Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats.
-
Differential actions of PAR2 and PAR1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases.
-
Differential effects of epidermal growth factor, somatomedin-C/insulin-like growth factor I, and transforming growth factor-beta on porcine granulosa cell deoxyribonucleic acid synthesis and cell proliferation.
-
Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein.
-
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.
-
Digital switching of local arginine density in a genetically encoded self-assembled polypeptide nanoparticle controls cellular uptake.
-
Diminished class II-associated Ii peptide binding to the juvenile dermatomyositis HLA-DQ alpha 1*0501/DQ beta 1*0301 molecule.
-
Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.
-
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.
-
Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species.
-
Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide.
-
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems.
-
Discovery of high-affinity peptide binders to BLyS by phage display.
-
Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.
-
Discovery of the Xenon-Protein Interactome Using Large-Scale Measurements of Protein Folding and Stability.
-
Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.
-
Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity.
-
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta.
-
Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage.
-
Distinct sensitivities to phosphate deprivation suggest that RGF peptides play disparate roles in Arabidopsis thaliana root development.
-
Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions.
-
Does eptifibatide confer a greater benefit to patients with unstable angina than with non-ST segment elevation myocardial infarction? Insights from the PURSUIT Trial.
-
Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma.
-
Drug delivery to solid tumors by elastin-like polypeptides.
-
Drug-company sponsorship and the Declaration of Helsinki.
-
Duration of eptifibatide infusion after percutaneous coronary intervention and outcomes among high-risk patients with non-ST-segment elevation acute coronary syndrome: insights from EARLY ACS.
-
Dynamics of the helix--coil transition in poly-L-ornithine.
-
ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.
-
ESPRIT in context: pharmacology matters!
-
Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor.
-
Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds.
-
Early versus delayed, provisional eptifibatide in acute coronary syndromes.
-
Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial.
-
Effect of Etelcalcetide vs Placebo on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: Two Randomized Clinical Trials.
-
Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity.
-
Effect of backbone flexibility on charge transfer rates in peptide nucleic acid duplexes.
-
Effect of clopidogrel with and without eptifibatide on tumor necrosis factor-alpha and C-reactive protein release after elective stenting: results from the CLEAR PLATELETS 1b study.
-
Effect of detergents on the thermal behavior of elastin-like polypeptides.
-
Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy).
-
Effect of eptifibatide on angiographic complications during percutaneous coronary intervention in the IMPACT--(Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis) II Trial.
-
Effect of eptifibatide on coronary flow reserve following coronary stent implantation (an ESPRIT substudy). Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy.
-
Effect of genetic circular permutation near the active site on the activity and stability of an enzyme inhibitor.
-
Effect of glycoprotein IIb/IIIa receptor inhibition on angiographic complications during percutaneous coronary intervention in the ESPRIT trial.
-
Effect of institutional volume and academic status on outcomes of coronary interventions: the IMPACT-II experience.
-
Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots.
-
Effect of multielement intravascular ultrasound on the anticoagulant potency of enoxaparin.
-
Effect of operator and institutional volume on clinical outcomes after percutaneous coronary interventions performed in Canada and the United States: a brief report from the Enhanced Suppression of the Platelet glycoprotein IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) study.
-
Effect of protein fusion on the transition temperature of an environmentally responsive elastin-like polypeptide: a role for surface hydrophobicity?
-
Effect of receptor-ligand affinity on the strength of endothelial cell adhesion.
-
Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.
-
Effectiveness of ecallantide in treating angiotensin-converting enzyme inhibitor-induced angioedema in the emergency department.
-
Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: immunosuppression, immunogenicity, and relation to immunosuppressive tumor products.
-
Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans.
-
Effects of Hofmeister Anions on the Phase Transition Temperature of Elastin-like Polypeptides
-
Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.
-
Effects of glucagonlike peptide I-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures.
-
Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men.
-
Effects of unfractionated heparin and glycoprotein IIb/IIIa antagonists versus bivalirdin on myeloperoxidase release from neutrophils.
-
Elastin-Like Polypeptides for Biomedical Applications.
-
Elastin-like polypeptides as a purification tag for recombinant proteins.
-
Elastin-like polypeptides as models of intrinsically disordered proteins.
-
Elastin-like polypeptides: biomedical applications of tunable biopolymers.
-
Elective percutaneous coronary intervention using broad-spectrum antiplatelet therapy (eptifibatide, clopidogrel, and aspirin) alone, without scheduled unfractionated heparin or other antithrombin therapy.
-
Electron capture dissociation mass spectrometry in characterization of peptides and proteins.
-
Electron capture dissociation mass spectrometry in characterization of post-translational modifications.
-
Electron transport complex I is required for CD8+ T cell function.
-
Enabling sublingual peptide immunization with molecular self-assemblies.
-
Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix.
-
Endogenous somatostatin-28 modulates postprandial insulin secretion. Immunoneutralization studies in baboons.
-
Enhanced efficacy of eptifibatide administration in patients with acute coronary syndrome requiring in-hospital coronary artery bypass grafting. PURSUIT Investigators.
-
Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition.
-
Enhancing Schwann cell migration using concentration gradients of laminin-derived peptides.
-
Enhancing human islet transplantation by localized release of trophic factors from PLG scaffolds.
-
Enhancing safety and outcomes with the newer antithrombotic and antiplatelet agents.
-
Enterogastrone-like effect of peptide YY is vagally mediated in the dog.
-
Enzymatic modification of proteins with a geranylgeranyl isoprenoid.
-
Enzyme occupancy measurement of intracellular protein tyrosine phosphatase 1B using photoaffinity probes.
-
Epidermal growth factor (EGF)-like transforming growth factor (TGF) activity and EGF receptors in ovine fetal tissues: possible role for TGF in ovine fetal development.
-
Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells.
-
Epitope mapping of the U1 small nuclear ribonucleoprotein particle in patients with systemic lupus erythematosus and mixed connective tissue disease.
-
Epitope tagging for tracking elastin-like polypeptides.
-
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
-
Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model.
-
Eptifibatide and low-dose tissue plasminogen activator in acute myocardial infarction: the integrilin and low-dose thrombolysis in acute myocardial infarction (INTRO AMI) trial.
-
Eptifibatide in coronary intervention: past time for the next chapter.
-
Eptifibatide in percutaneous coronary intervention. A review.
-
Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa.
-
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.
-
Ethics and equipoise: rationale for a placebo-controlled study design of platelet glycoprotein IIb/IIIa inhibition in coronary intervention.
-
Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis.
-
Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy.
-
Evaluation of in vitro antifungal activity of LY121019.
-
Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
-
Evidence of a role for heterotrimeric GTP-binding proteins in endosome fusion.
-
Evolution of the gene encoding mitochondrial intermediate peptidase and its cosegregation with the A mating-type locus of mushroom fungi.
-
Evolving the use of peptides as components of biomaterials
-
Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans.
-
Exenatide and rimonabant: new treatments that may be useful in the management of diabetes and obesity.
-
Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous system.
-
Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.
-
Expanded polyglutamine stretches form an 'aggresome'.
-
Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome.
-
Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases.
-
Exploration of the Potential Role of Serum Albumin in the Delivery of Cu(I) to Ctr1.
-
Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies.
-
Exploring the conformational preferences of 20-residue peptides in isolation: Ac-Ala19-Lys + H(+)vs. Ac-Lys-Ala19 + H(+) and the current reach of DFT.
-
Expression and purification of recombinant proteins from Escherichia coli: Comparison of an elastin-like polypeptide fusion with an oligohistidine fusion.
-
Expression of human T cell receptor-gamma delta structural forms.
-
Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas.
-
Expression, purification and primary crystallographic study of human androgen receptor in complex with DNA and coactivator motifs.
-
Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases.
-
Extensive thrombus prior to elective percutaneous coronary intervention.
-
Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review.
-
FIGQY phosphorylation defines discrete populations of L1 cell adhesion molecules at sites of cell-cell contact and in migrating neurons.
-
Fabrication of Elastin-Like polypeptide Nanoparticles for Drug Delivery by Electrospraying
-
Fabrication of a reversible protein array directly from cell lysate using a stimuli-responsive polypeptide.
-
Facile fabrication of "dual click" one- and two-dimensional orthogonal peptide concentration gradients.
-
Facilitated percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: results from the prematurely terminated ADdressing the Value of facilitated ANgioplasty after Combination therapy or Eptifibatide monotherapy in acute Myocardial Infarction (ADVANCE MI) trial.
-
Farnesylation of nonpeptidic thiol compounds by protein farnesyltransferase.
-
Fast and forceful refolding of stretched alpha-helical solenoid proteins.
-
Fasting glucose, NT-proBNP, treatment with eptifibatide, and outcomes in non-ST-segment elevation acute coronary syndromes: An analysis from EARLY ACS.
-
Fatal Scopulariopsis brevicaulis infection in a paediatric stem-cell transplant patient treated with voriconazole and caspofungin and a review of Scopulariopsis infections in immunocompromised patients.
-
Fetal alveolar epithelial cells contain [D-Ala(2)]-deltorphin I-like immunoreactivity: delta- and mu-opiate receptors mediate opposite effects in developing lung.
-
Fibrillar peptide gels in biotechnology and biomedicine.
-
Fibrin specific peptides derived by phage display: characterization of peptides and conjugates for imaging.
-
Fibroblast growth factor 21 mediates specific glucagon actions.
-
Fluorescent peptide displacement as a general assay for screening small molecule libraries against RNA.
-
Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.
-
Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans.
-
Found in translation: applications of protein and peptide molecular diversity.
-
Frequency, clinical and angiographic characteristics, and outcomes of high-risk non-ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions.
-
Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene.
-
Functional analysis of antigen-specific T lymphocytes by serial measurement of gene expression in peripheral blood mononuclear cells and tumor specimens.
-
Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex.
-
Functionalized micellar assemblies prepared via block copolymers synthesized by living free radical polymerization upon peptide-loaded resins.
-
Further studies on the composition and spectral properties of the photochemical reaction centers of bacteriochlorophyll b-containing bacteria.
-
Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins.
-
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
-
Fusions of elastin-like polypeptides to pharmaceutical proteins.
-
GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice.
-
GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats.
-
GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats.
-
Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy.
-
Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary.
-
Gastrin-releasing peptide (mammalian bombesin) gene expression in health and disease.
-
Gastrin-releasing peptide gene expression in developing, hyperplastic, and neoplastic human thyroid C-cells.
-
Gastrin-releasing peptide gene expression in small cell and large cell undifferentiated lung carcinomas.
-
Generation of neuronal intranuclear inclusions by polyglutamine-GFP: analysis of inclusion clearance and toxicity as a function of polyglutamine length.
-
Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome.
-
Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain.
-
Genetically Encoded Elastin-Like Polypeptides for Drug Delivery.
-
Genetically Encoded Stealth Nanoparticles of a Zwitterionic Polypeptide-Paclitaxel Conjugate Have a Wider Therapeutic Window than Abraxane in Multiple Tumor Models.
-
Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy.
-
Genetically Engineered Nanoparticles of Asymmetric Triblock Polypeptide with a Platinum(IV) Cargo Outperforms a Platinum(II) Analog and Free Drug in a Murine Cancer Model.
-
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
-
Genetically encoded elastin-like polypeptide nanoparticles for drug delivery.
-
Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly.
-
Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin.
-
Giant vesicle bilayers composed of mixtures of lipids, cholesterol and polypeptides. Thermomechanical and (mutual) adherence properties.
-
Glatiramer acetate: successful desensitization for treatment of multiple sclerosis.
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.
-
Global distribution and outcomes for Candida species causing invasive candidiasis: results from an international randomized double-blind study of caspofungin versus amphotericin B for the treatment of invasive candidiasis.
-
Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.
-
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats.
-
Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis.
-
Glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
-
Glycoprotein IIb/IIIa receptor inhibitors: putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective.
-
Gradated assembly of multiple proteins into supramolecular nanomaterials.
-
Graft-versus-host disease: the viewpoint from the donor T cell.
-
Growth factors modulate gonadotropin receptor induction in granulosa cell cultures.
-
Gz, a guanine nucleotide-binding protein with unique biochemical properties.
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.
-
HIV type 1 V3 region primer-induced antibody suppression is overcome by administration of C4-V3 peptides as a polyvalent immunogen.
-
HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.
-
HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.
-
Heuristics for the Optimal Presentation of Bioactive Peptides on Polypeptide Micelles.
-
High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats.
-
High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes.
-
High-throughput screening assay for the tunable selection of protein ligands.
-
Home surveillance program prevents interstage mortality after the Norwood procedure.
-
How cations change peptide structure.
-
How do halogen substituents contribute to protein-binding interactions? A thermodynamic study of peptide ligands with diverse aryl halides.
-
Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance.
-
Human Factor XIII from plasma and platelets. Molecular weights, subunit structures, proteolytic activation, and cross-linking of fibrinogen and fibrin.
-
Human IFN-gamma production is inhibited by a synthetic peptide homologous to retroviral envelope protein.
-
Human dendritic cells transfected with RNA encoding prostate-specific antigen stimulate prostate-specific CTL responses in vitro.
-
Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide(280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity.
-
Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity.
-
Hydration and conformational mechanics of single, end-tethered elastin-like polypeptides.
-
Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers.
-
Hydrogel Design of Experiments Methodology to Optimize Hydrogel for iPSC-NPC Culture
-
Hydrogels formed by multiple peptide ligation reactions to fasten corneal transplants.
-
Hydrogen bonding of beta-turn structure is stabilized in D(2)O.
-
Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.
-
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.
-
Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions.
-
Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus.
-
Identification of a structural gene for a RNA polymerase II polypeptide in Drosophila melanogaster and mammalian species.
-
Identification of a synthetic peptide that mimics an HIV glycoprotein 120 envelope conformational determinant exposed following ligation of glycoprotein 120 by CD4.
-
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
-
Identification of ligand-selective peptide antagonists of the mineralocorticoid receptor using phage display.
-
Identification of molecular signature of head and neck cancer stem-like cells.
-
Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension.
-
Identification of substrate specificity determinants for the cell cycle-regulated NIMA protein kinase.
-
Identification of troponin C antagonists from a phage-displayed random peptide library.
-
Identifying key components of the PrPC-PrPSc replicative interface.
-
Identifying protein phosphatase 2A interacting proteins using the yeast two-hybrid method.
-
Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention.
-
Immune responses to coiled coil supramolecular biomaterials.
-
Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity.
-
Immunization with recombinant canarypox vectors expressing membrane-anchored glycoprotein 120 followed by glycoprotein 160 boosting fails to generate antibodies that neutralize R5 primary isolates of human immunodeficiency virus type 1.
-
Immunocompetent murine model of cancer cachexia for head and neck squamous cell carcinoma.
-
Immunodominant sites of human T cell lymphotropic virus type 1 envelope protein for murine helper T cells.
-
Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry.
-
Immunolocalization of PKC zeta in rat photoreceptor inner segments.
-
Immunological properties of avian oncornavirus polypeptides.
-
Immunomodulatory peptides with high binding affinity for class II MHC molecules for the prevention of graft-versus-host disease.
-
Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.
-
Immunotherapy of cancer with dendritic-cell-based vaccines.
-
Impact of eptifibatide on early ischemic events in acute ischemic coronary syndromes: a review of the IMPACT II trial. Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis.
-
Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
-
Impact of vibrational entropy on the stability of unsolvated peptide helices with increasing length
-
Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens.
-
Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides.
-
Improved speciation of dissolved organic nitrogen in natural waters: amide hydrolysis with fluorescence derivatization.
-
Improved speed and stability of ST-segment recovery with reduced-dose tenecteplase and eptifibatide compared with full-dose tenecteplase for acute ST-segment elevation myocardial infarction.
-
Improving peptide-MHC class I binding prediction for unbalanced datasets.
-
In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair.
-
In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model.
-
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.
-
In utero priming of highly functional effector T cell responses to human malaria.
-
In vitro and in vivo evaluation of a water-in-oil microemulsion system for enhanced peptide intestinal delivery.
-
In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds.
-
In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.
-
In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides.
-
In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus.
-
In vitro selection of an RNA epitope immunologically cross-reactive with a peptide.
-
In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy.
-
In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide.
-
In-hospital costs of coronary stent implantation with and without eptifibatide (the ESPRIT Trial). Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin.
-
Incidence and predictors of major vascular complications after percutaneous coronary intervention in the glycoprotein IIb/IIIa platelet inhibitor era.
-
Incorporation of designed extended chromophores into amphiphilic 4-helix bundle peptides for nonlinear optical biomolecular materials.
-
Increased expression of galanin in the rat superior cervical ganglion after pre- and postganglionic nerve lesions.
-
Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression.
-
Incretin mimetics as emerging treatments for type 2 diabetes.
-
Indirect fluorometric detection of tryptic digests separated by capillary zone electrophoresis.
-
Induction and spontaneous regression of pulmonary neuroendocrine cell hyperplasia in a hamster model.
-
Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.
-
Induction of cytotoxic T lymphocytes with dendritic cells transfected with human papillomavirus E6 and E7 RNA: implications for cervical cancer immunotherapy.
-
Induction of intracellular cAMP by a synthetic retroviral envelope peptide: a possible mechanism of immunopathogenesis in retroviral infections.
-
Infectious mononucleosis patients temporarily recognize a unique, cross-reactive epitope of Epstein-Barr virus nuclear antigen-1.
-
Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I.
-
Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis.
-
Inhibition of central amylin signaling increases food intake and body adiposity in rats.
-
Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial.
-
Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth.
-
Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors.
-
Inhibition of human natural killer cell activity by a synthetic peptide homologous to a conserved region in the retroviral protein, p15E.
-
Inhibition of interleukin-2 and interferon-gamma by an HIV-1 Nef-encoded synthetic peptide.
-
Inhibition of lymphocyte proliferation by a synthetic peptide homologous to envelope proteins of human and animal retroviruses.
-
Inhibition of lymphocyte proliferation by a synthetic peptide homologous to retroviral envelope proteins.
-
Inhibition of murine cytotoxic T lymphocyte activity by a synthetic retroviral peptide and abrogation of this activity by IL.
-
Inhibition of platelet aggregation with a glycoprotein IIb-IIIa antagonist does not prevent thrombin generation in patients undergoing thrombolysis for acute myocardial infarction.
-
Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening.
-
Inhibition of protein kinase C by a peptide conjugate homologous to a domain of the retroviral protein p15E.
-
Inhibition of protein misfolding/aggregation using polyglutamine binding peptide QBP1 as a therapy for the polyglutamine diseases.
-
Inhibitory effects of a phage-derived peptide on Au nanocrystal nucleation and growth.
-
Inhibitory regulation of rat exocrine pancreas by peptide YY and pancreatic polypeptide.
-
Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model.
-
Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.
-
Injectable tissue integrating networks from recombinant polypeptides with tunable order.
-
Inositol pyrophosphates modulate S phase progression after pheromone-induced arrest in Saccharomyces cerevisiae.
-
Integramides A and B, two novel non-ribosomal linear peptides containing nine C(alpha)-methyl amino acids produced by fungal fermentations that are inhibitors of HIV-1 integrase.
-
Integrated in silico and experimental discovery of trimeric peptide ligands targeting Butyrylcholinesterase.
-
Integrating antithrombin and antiplatelet therapies with early invasive management for non-ST-segment elevation acute coronary syndromes.
-
Integrating valve-inspired design features into poly(ethylene glycol) hydrogel scaffolds for heart valve tissue engineering.
-
Integrin alpha 6 regulates glioblastoma stem cells.
-
Interaction of endoplasmic reticulum chaperone GRP94 with peptide substrates is adenine nucleotide-independent.
-
Interaction of retinal glial cells with collagen matrices: implications for pathogenesis of cell-mediated vitreous traction.
-
Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3.
-
Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction.
-
Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species.
-
International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates.
-
Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction.
-
Intracoronary bolus administration of eptifibatide during percutaneous coronary stenting for non ST elevation myocardial infarction and unstable angina.
-
Intracoronary eptifibatide bolus administration during percutaneous coronary revascularization for acute coronary syndromes with evaluation of platelet glycoprotein IIb/IIIa receptor occupancy and platelet function: the Intracoronary Eptifibatide (ICE) Trial.
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Intradialytic hypertension and its association with endothelial cell dysfunction.
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Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations.
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Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
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Intrathecal administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury.
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Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot.
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Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection.
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Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor.
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Investigating the Role of Class I Adenylate-Forming Enzymes in Natural Product Biosynthesis.
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Investigation of a synthetic peptide as immunogen for a variant epidermal growth factor receptor associated with gliomas.
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Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure.
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Is glycoprotein IIb/IIIa antagonism as effective in women as in men following percutaneous coronary intervention?. Lessons from the ESPRIT study.
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Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.
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Isolation of a mycoplasma-specific binding peptide from an unbiased phage-displayed peptide library.
-
Isolation of monoclonal antibodies with predetermined conformational epitope specificity.
-
Iterative in situ click chemistry creates antibody-like protein-capture agents.
-
Jumping to rafts: gatekeeper role of bilayer elasticity.
-
Kinetics of TCR use in response to repeated epitope-specific immunization.
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L-selectin dimerization enhances tether formation to properly spaced ligand.
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Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection.
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Laminin alpha 2 enables glioblastoma stem cell growth.
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Lanthanide-binding tags as versatile protein coexpression probes.
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Larval release behaviors in the Caribbean spiny lobster, Panulirus argus: role of peptide pheromones.
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Laryngeal Edema in a Child with Hereditary Angioedema with Normal C1 Inhibitor.
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Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy.
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Leukocyte chemoattractant peptides from the serpin heparin cofactor II.
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Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure.
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Ligand interactions in the adenosine nucleotide-binding domain of the Hsp90 chaperone, GRP94. II. Ligand-mediated activation of GRP94 molecular chaperone and peptide binding activity.
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Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer.
-
Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia.
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Light-Triggered Myosin Activation for Probing Dynamic Cellular Processes
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Lipophilic peptides for gene delivery.
-
Localization and characterization of neuropeptide Y/peptide YY receptors in the brain of the smooth dogfish (Mustelis canis).
-
Localization of RNA tumor virus polypeptides. I. Isolation of further virus substructures.
-
Localization of specific binding sites for bombesin in the canine gastrointestinal tract.
-
Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery.
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Long-term efficacy of platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention.
-
Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration.
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Lung endocrine cell markers, peptides, and amines.
-
Lysine-Specific Demethylase 1A (KDM1A/LSD1): Product Recognition and Kinetic Analysis of Full-Length Histones.
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MHC class I-peptide interactions and TCR recognition.
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MHC class I-presented lung cancer-associated tumor antigens identified by immunoproteomics analysis are targets for cancer-specific T cell response.
-
Macrophage accumulation in mice is inhibited by low molecular weight products from murine leukemia viruses.
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Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study.
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Management of patients with acute coronary syndromes in the United States by platelet glycoprotein IIb/IIIa inhibition. Insights from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
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Mapping Tertiary Interactions in Protein Folding Reactions: A Novel Mass Spectrometry- and Chemical Synthesis-Based Approach
-
Mapping of homologous, amino-terminal neutralizing regions of human T-cell lymphotropic virus type I and II gp46 envelope glycoproteins.
-
Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46.
-
Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells.
-
Mass Spectrometry and Ion Mobility Characterization of Bioactive Peptide-Synthetic Polymer Conjugates.
-
Mass spectrometry of N-methylated peptide derivatives.
-
Mast cell activators: a new class of highly effective vaccine adjuvants.
-
Mastoparan, a wasp venom peptide, identifies two discrete mechanisms for elevating cytosolic calcium and inositol trisphosphates in human polymorphonuclear leukocytes.
-
Maternally inherited peptides as strain-specific chemosignals.
-
Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes.
-
Measurement of cytokine release at the single cell level using the ELISPOT assay.
-
Mechanism of Side Chain-Controlled Proton Conductivity in Bioinspired Peptidic Nanostructures.
-
Mechanism of insulin incorporation into alpha 2-macroglobulin: implications for the study of peptide and growth factor binding.
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Mechanistic Insight into the Suppression of Polyglutamine Aggregation by SRCP1.
-
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease.
-
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners.
-
Metaprotein expression modeling for label-free quantitative proteomics.
-
Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I).
-
Methionine to glutamine substitutions in the C-terminal domain of calmodulin impair the activation of three protein kinases.
-
Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment.
-
Micropatterning biological molecules on a polymer surface using elastomeric microwells.
-
Mimosine targets serine hydroxymethyltransferase.
-
Minor myocardial damage and prognosis: are spontaneous and percutaneous coronary intervention-related events different?
-
Minors come of age: Minor histocompatibility antigens and graft-versus-host disease.
-
Misexpression of ptf1a in cortical pyramidal cells in vivo promotes an inhibitory peptidergic identity.
-
Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver.
-
Mitogenic effect of neuropeptide Y in rat vascular smooth muscle cells.
-
Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region.
-
Mixed peptide sequencing and the FASTF/FASTS algorithms.
-
Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1.
-
Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1.
-
Modifiable risk factors for vascular access site complications in the IMPACT II Trial of angioplasty with versus without eptifibatide. Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis.
-
Modification of Poly(propylene fumarate)-Bioglass Composites with Peptide Conjugates to Enhance Bioactivity.
-
Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading.
-
Modification of materials with bioactive peptides.
-
Modification of polyurethaneurea with PEG and YIGSR peptide to enhance endothelialization without platelet adhesion.
-
Modification of surfaces with cell adhesion peptides alters extracellular matrix deposition.
-
Modulating adaptive immune responses to peptide self-assemblies.
-
Modulating protein structure with fluorous amino acids: increased stability and native-like structure conferred on a 4-helix bundle protein by hexafluoroleucine.
-
Modulating the mechanical properties of self-assembled peptide hydrogels via native chemical ligation.
-
Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structures.
-
Molecular Docking and Molecular Dynamics (MD) Simulation of Human Anti-Complement Factor H (CFH) Antibody Ab42 and CFH Polypeptide.
-
Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes.
-
Molecular cloning of the cDNA for androgen-dependent sperm-coating glycoproteins secreted by the rat epididymis.
-
Molecular description of the LCST behavior of an elastin-like polypeptide.
-
Molecular mechanical properties of short-sequence peptide enzyme mimics.
-
Monitoring cellular immune responses to cancer immunotherapy.
-
Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer.
-
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
-
Moving beyond disease to function: Physiological roles for polyglutamine-rich sequences in cell decisions.
-
Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT Investigators.
-
Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses.
-
Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices.
-
Multiple conformations of PEVK proteins detected by single-molecule techniques.
-
Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.
-
Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing.
-
N-succinimidyl 3-[(131)I]iodo-4-phosphonomethylbenzoate ([(131)I]SIPMB), a negatively charged substituent-bearing acylation agent for the radioiodination of peptides and mAbs.
-
NDRG4 is required for cell cycle progression and survival in glioblastoma cells.
-
NMR-derived solution conformations of a hybrid synthetic peptide containing multiple epitopes of envelope protein gp120 from the RF strain of human immunodeficiency virus.
-
Nanomechanics of streptavidin hubs for molecular materials.
-
Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity.
-
Nanoscale packed-capillary liquid chromatography coupled with mass spectrometry using a coaxial continuous-flow fast atom bombardment interface.
-
Native like helices in a specially designed β peptide in the gas phase.
-
Nature of Amorphous Hydrophilic Block Affects Self-Assembly of an Artificial Viral Coat Polypeptide.
-
Need radioprotection? A MEPE/OF45 mimetic may do the job.
-
Neuropeptide Y and galanin binding sites in rat and monkey lumbar dorsal root ganglia and spinal cord and effect of peripheral axotomy.
-
Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator.
-
Neutralization of homologous and heterologous oncornaviruses by antisera against the p15(E) and gp71 polypeptides of Friend murine leukemia virus.
-
New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor.
-
Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.
-
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics.
-
Nitroxide conjugate of a thermally responsive elastin-like polypeptide for noninvasive thermometry.
-
Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation.
-
Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli.
-
Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1.
-
Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles.
-
Notch promotes radioresistance of glioma stem cells.
-
Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity.
-
Novel dosing regimen of eptifibatide in planned coronary stent implantation (ESPRIT): a randomised, placebo-controlled trial.
-
Novel peptide inhibitors of angiotensin-converting enzyme 2.
-
Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.
-
Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22.
-
OP449 inhibits breast cancer growth without adverse metabolic effects.
-
Obestatin and adropin in Prader-Willi syndrome and nonsyndromic obesity: Associations with weight, BMI-z, and HOMA-IR.
-
Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells.
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Once-Weekly Exenatide and Cardiovascular Outcomes in Type 2 Diabetes.
-
Oncogenic mutations in ras create HLA-A2.1 binding peptides but affect their extracellular antigen processing.
-
Optical coding of mammalian cells using semiconductor quantum dots.
-
Optimal duration of eptifibatide infusion in percutaneous coronary intervention (an ESPRIT substudy).
-
Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay.
-
Optimizing PLG nanoparticle-peptide delivery platforms for transplantation tolerance using an allogeneic skin transplant model.
-
Order out of disorder: working cycle of an intrinsically unfolded chaperone.
-
Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages.
-
Outcomes of patients with acute coronary syndromes and prior coronary artery bypass grafting: results from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
-
Outer membrane of avian myeloblastosis virus.
-
Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors.
-
PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.
-
Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.
-
Passively transmitted gp41 antibodies in babies born from HIV-1 subtype C-seropositive women: correlation between fine specificity and protection.
-
Peptide Functionalized Gold Nanorods for the Sensitive Detection of a Cardiac Biomarker Using Plasmonic Paper Devices.
-
Peptide YY inhibits meal-stimulated pancreatic and gastric secretion.
-
Peptide YY release by fatty acids is sufficient to inhibit gastric emptying in dogs.
-
Peptide YY: metabolism and effect on pancreatic secretion in dogs.
-
Peptide affinity reagents for AAV capsid recognition and purification.
-
Peptide antagonists of the human estrogen receptor.
-
Peptide binding proclivities of calcium loaded calbindin-D28k.
-
Peptide hormone regulation of islet cells.
-
Peptide specificity determinants at P-7 and P-6 enhance the catalytic efficiency of Ca2+/calmodulin-dependent protein kinase I in the absence of activation loop phosphorylation.
-
Peptide-Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite-Mediated Nitration.
-
Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells.
-
Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells.
-
Peptide-derivatized shell-cross-linked nanoparticles. 1. Synthesis and characterization.
-
Peptide-derivatized shell-cross-linked nanoparticles. 2. Biocompatibility evaluation.
-
Peptide-functionalized oxime hydrogels with tunable mechanical properties and gelation behavior.
-
Peptide-mediated targeting of the islets of Langerhans.
-
Peptide-polymer bioconjugates: hybrid block copolymers generated via living radical polymerizations from resin-supported peptides.
-
Peptide/MHC tetramer-based sorting of CD8⁺ T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an underlying restricted repertoire.
-
Peptides from second extracellular loop of C-C chemokine receptor type 5 (CCR5) inhibit diverse strains of HIV-1.
-
Peptidyl membrane-interactive molecules are cytotoxic to prostatic cancer cells in vitro.
-
Percutaneous coronary intervention in a patient with immune thrombocytopenia purpura.
-
Perioperative management of patients on clopidogrel (Plavix) undergoing major lung resection.
-
Peripartum management of dual antiplatelet therapy and neuraxial labor analgesia after bare metal stent insertion for acute myocardial infarction.
-
Peripheral blood mononuclear cells from patients with bullous pemphigoid have an increased frequency of response to synthetic peptides encoded by BPAG1.
-
Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation.
-
Perspectives on the future of platelet glycoprotein IIb/IIIa blockade therapy.
-
Phage display screening for peptides that inhibit polyglutamine aggregation.
-
Pharmacodynamics and pharmacokinetics of higher-dose, double-bolus eptifibatide in percutaneous coronary intervention.
-
Pharmacogenomic effects of apolipoprotein e on intracerebral hemorrhage.
-
Phase 2 study of the g209-2M melanoma peptide vaccine and low-dose interleukin-2 in advanced melanoma: Cancer and Leukemia Group B 509901.
-
Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides.
-
Phosphatases driving mitosis: pushing the gas and lifting the brakes.
-
Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria.
-
Phosphorylation of Gz in human platelets. Selectivity and site of modification.
-
Phosphorylation of telokin by cyclic nucleotide kinases and the identification of in vivo phosphorylation sites in smooth muscle.
-
Photo-Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano- to Microgels of Intrinsically Disordered Polypeptides.
-
Photoaffinity labelling of mammalian beta-adrenergic receptors: metal-dependent proteolysis explains apparent heterogeneity.
-
Photochemical energy conversion in a helical oligoproline assembly.
-
Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering.
-
Phylogenetic distribution of the bacteriocin repertoire of lactic acid bacteria species associated with artisanal cheese.
-
Piecewise All-Atom SMD Simulations Reveal Key Secondary Structures in Luciferase Unfolding Pathway.
-
Piezo1 is a mechanically activated ion channel and mediates pressure induced pancreatitis.
-
Platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention: the ESPRIT trial: a randomized controlled trial.
-
Platelet glycoprotein IIb/IIIa receptor antagonists in non-ST segment elevation acute coronary syndromes: a review and guide to patient selection.
-
Platelet-derived growth factor enhances granulosa cell luteinizing hormone receptor induction by follicle-stimulating hormone and serum.
-
Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention: results of the GOLD (AU-Assessing Ultegra) multicenter study.
-
PolyQ-dependent RNA-protein assemblies control symmetry breaking.
-
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity.
-
Polyglutamine domain proteins with expanded repeats bind neurofilament, altering the neurofilament network.
-
Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases?
-
Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria.
-
Polymorphisms at the microRNA binding-site of the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer.
-
Polypeptides of avian RNA tumor viruses. 1. Isolation and physical and chemical analysis.
-
Polypeptides of avian RNA tumor viruses. 3. Purification and identification of a DNA synthesizing enzyme.
-
Polypeptides of avian RNA tumor viruses. II. Serological characterization.
-
Polypeptides of avian RNA tumor viruses. IV. Components of the viral envelope.
-
Polypeptides of avian RNA tumor viruses. V. Analysis of the virus core.
-
Polypeptides of endogenous avian C-type viruses: their detection in the plasma membrane of normal and infected cells.
-
Polypeptides of mammalian oncornaviruses. I. Isolation and serological analysis polypeptides from murine and feline C-type viruses.
-
Polypeptides of mammalian oncornaviruses. II Characterization of murine leukemia virus polypeptide (p 15) bearing interspecies reactivity.
-
Polypeptides of mammalian oncornaviruses. III. Localization of p 15 and reactivity with natural antibody.
-
Polypeptides of mammalian oncornaviruses. IV. Structural components of murine leukemia virus released as soluble antigens in cell culture.
-
Power calculations for large multi-arm placebo-controlled studies of dichotomous outcomes.
-
Power considerations for trials of two experimental arms versus a standard active control or placebo.
-
Practical Considerations in the Design and Use of Immunologically Active Fibrillar Peptide Assemblies.
-
Practice patterns and clinical outcomes among non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients presenting to primary and tertiary hospitals: insights from the EARLY glycoprotein IIb/IIIa inhibition in NSTE-ACS (EARLY-ACS) trial.
-
Precision and linearity targets for validation of an IFNgamma ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides.
-
Predicting transition temperatures of elastin-like polypeptide fusion proteins.
-
Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. The PURSUIT Investigators.
-
Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.
-
Premature translational termination products are rapidly degraded substrates for MHC class I presentation.
-
Preparation of peptide-loaded dendritic cells for cancer immunotherapy.
-
Present and evolving role of eptifibatide in the treatment of acute coronary syndromes.
-
Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila.
-
Priming for virus-specific CD8+ but not CD4+ cytotoxic T lymphocytes with synthetic lipopeptide is influenced by acylation units and liposome encapsulation.
-
Priming of anti-human immunodeficiency virus (HIV) CD8+ cytotoxic T cells in vivo by carrier-free HIV synthetic peptides.
-
Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes. PURSUIT Investigators. Platelet IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy.
-
Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction.
-
Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate.
-
Production and characterization of antipeptide antibodies against human O6-methylguanine-DNA methyltransferase.
-
Profiling natural product biosynthesis.
-
Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
-
Prognostic importance of concomitant heparin with eptifibatide in acute coronary syndromes. PURSUIT Investigators. Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy.
-
Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromes.
-
Progress Toward the Clinical Translation of Bioinspired Peptide and Protein Assemblies.
-
Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex.
-
Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor.
-
Protease activity of normal and PHA stimulated human lymphocytes.
-
Protease degradable tethers for controlled and cell-mediated release of nanoparticles in 2-and 3-dimensions
-
Protease-activated quantum dot probes.
-
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.
-
Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release.
-
Protein fragment domains identified using 2D gel electrophoresis/MALDI-TOF.
-
Protein polymer hydrogels by in situ, rapid and reversible self-gelation.
-
Protein purification by fusion with an environmentally responsive elastin-like polypeptide: effect of polypeptide length on the purification of thioredoxin.
-
Protein signature analysis: a practical new approach for studying structure-activity relationships in peptides and proteins.
-
Protein-polymer conjugation-moving beyond PEGylation.
-
Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis.
-
Proteolytic domains of the epidermal growth factor receptor of human placenta.
-
Proteome analyses using accurate mass and elution time peptide tags with capillary LC time-of-flight mass spectrometry.
-
Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease.
-
Purification and characterization of a lecithin-D(-)- -hydroxybutyrate dehydrogenase complex.
-
Purification of an elastin-like fusion protein by microfiltration.
-
Purification of messenger ribonucleoprotein particles from rabbit reticulocytes by zonal centrifugation in metrizamide.
-
Purification of recombinant proteins by fusion with thermally-responsive polypeptides.
-
Qa-1 restriction of CD8+ suppressor T cells.
-
Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands.
-
Quantification of the binding affinity of a specific hydroxyapatite binding peptide.
-
Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides.
-
Quantifying kinetic paths of protein folding.
-
Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
-
Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density.
-
Quantitative and selective fluorophore labeling of phosphoserine on peptides and proteins: characterization at the attomole level by capillary electrophoresis and laser-induced fluorescence.
-
Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides.
-
Quantum confined peptide assemblies with tunable visible to near-infrared spectral range.
-
Quiescent phenotype of tumor-specific CD8+ T cells following immunization.
-
RGF1 controls root meristem size through ROS signalling.
-
RNA Controls PolyQ Protein Phase Transitions.
-
ROCK1 phosphorylates and activates zipper-interacting protein kinase.
-
Rabbits immunized with a peptide encoded for by the 230-kD bullous pemphigoid antigen cDNA develop an enhanced inflammatory response to UVB irradiation: a potential animal model for bullous pemphigoid.
-
Racial differences in circulating mitochondria-derived peptides may contribute to prostate cancer health disparities.
-
Radial versus femoral access, bleeding and ischemic events in patients with non-ST-segment elevation acute coronary syndrome managed with an invasive strategy.
-
Radiolabeling and in vitro evaluation of (67)Ga-NOTA-modular nanotransporter--a potential Auger electron emitting EGFR-targeted radiotherapeutic.
-
Radioreceptor assay of adrenocorticotropic hormone: new approach to assay of polypeptide hormones in plasma.
-
Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Integrilin to Minimise Platelet Aggregation and Coronary Thrombosis-II.
-
Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, and Eptifibatide.
-
Randomized evaluation of the efficacy of enoxaparin versus unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes receiving the glycoprotein IIb/IIIa inhibitor eptifibatide. Long-term results of the Integrilin and Enoxaparin Randomized Assessment of Acute Coronary Syndrome Treatment (INTERACT) trial.
-
Randomized evaluation of the safety and efficacy of enoxaparin versus unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes receiving the glycoprotein IIb/IIIa inhibitor eptifibatide.
-
Randomized peptide assemblies for enhancing immune responses to nanomaterials.
-
Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium.
-
Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution.
-
Rapid separation and characterization of protein and peptide mixtures using 1.5 microns diameter non-porous silica in packed capillary liquid chromatography/mass spectrometry.
-
Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors.
-
Rational identification of a novel peptide for targeting nanocarriers to 9L glioma.
-
Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial.
-
Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo.
-
Re-evaluating the role of heat-shock protein-peptide interactions in tumour immunity.
-
Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition.
-
Reaper-induced apoptosis in a vertebrate system.
-
Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity.
-
Recent antiplatelet drug trials in the acute coronary syndromes. Clinical interpretation of PRISM, PRISM-PLUS, PARAGON A and PURSUIT.
-
Recent trends in protein and peptide-based biomaterials for advanced drug delivery.
-
Recently Designed Multivalent Spike Binders Cannot Bind Multivalently─How Do They Achieve Enhanced Avidity to SARS-CoV-2?
-
Receptor biophysics and biochemistry. Enzymes.
-
Recognition of lysine-rich peptide ligands by murine cortactin SH3 domain: CD, ITC, and NMR studies.
-
Recombinant Synthesis of Hybrid Lipid-Peptide Polymer Fusions that Self-Assemble and Encapsulate Hydrophobic Drugs.
-
Reconstruction of mechanical unfolding and refolding pathways of proteins with atomic force spectroscopy and computer simulations.
-
Recurrent ischemia during continuous 12-lead ECG-ischemia monitoring in patients with acute coronary syndromes treated with eptifibatide: relation with death and myocardial infarction. PURSUIT ECG-Ischemia Monitoring Substudy Investigators. Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy.
-
Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.
-
Red blood cell and fibroblast membranes in Duchenne and myotonic muscular dystrophy.
-
Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP.
-
Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors.
-
Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy.
-
Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition.
-
Regulation of ribosome detachment from the mammalian endoplasmic reticulum membrane.
-
Regulation of translation and transcription of messenger RNA during early embryonic development.
-
Regulators of G protein signaling proteins as determinants of the rate of desensitization of presynaptic calcium channels.
-
Relationship of creatine kinase-myocardial band release to Thrombolysis in Myocardial Infarction perfusion grade after intracoronary stent placement: an ESPRIT substudy.
-
Relaxation spectrometry of biological systems.
-
Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition.
-
Resistance of Zwitterionic Peptide Monolayers to Biofouling.
-
Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence.
-
Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper.
-
Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo.
-
Right ventricular gene therapy with a beta-adrenergic receptor kinase inhibitor improves survival after pulmonary artery banding.
-
Risuteganib Protects against Hydroquinone-induced Injury in Human RPE Cells.
-
Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.
-
Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase.
-
Role of neuropeptides in the regulation of feeding behavior: a review of cholecystokinin, bombesin, neuropeptide Y, and galanin.
-
Role of transmethylation reactions in cellular motility and phagocytosis.
-
Roundtable panel discussion: the role of glycoprotein IIb-IIIa receptor inhibitors in acute ischemic coronary syndromes.
-
Routine early eptifibatide versus delayed provisional use at percutaneous coronary intervention in high-risk non-ST-segment elevation acute coronary syndromes patients: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome trial.
-
SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.
-
SNPselector: a web tool for selecting SNPs for genetic association studies.
-
SRCP1 Conveys Resistance to Polyglutamine Aggregation.
-
SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.
-
STT3A, C1orf24, TFF3: putative markers for characterization of follicular thyroid neoplasms from fine-needle aspirates.
-
SVM-based prediction of linear B-cell epitopes using Bayes Feature Extraction.
-
Safety and efficacy of adjusted-dose eptifibatide in patients with acute coronary syndromes and reduced renal function.
-
Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AGIS Group and L'Agence Nationale de Recherches sur Le Sida.
-
Scedosporium prolificans osteomyelitis in an immunocompetent child treated with voriconazole and caspofungin, as well as locally applied polyhexamethylene biguanide.
-
Scythe: a novel reaper-binding apoptotic regulator.
-
Secondary structure of a leucine zipper determined by nuclear magnetic resonance spectroscopy.
-
Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA.
-
Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA.
-
Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORgamma.
-
Selective inhibition of JNK with a peptide inhibitor attenuates pain hypersensitivity and tumor growth in a mouse skin cancer pain model.
-
Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.
-
Selective modification of antigen-specific T cells by RNA electroporation.
-
Self-Assembling Peptide Gels for 3D Prostate Cancer Spheroid Culture.
-
Self-assembled hybrid elastin-like polypeptide/silica nanoparticles enable triggered drug release.
-
Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope.
-
Self-assembling chimeric polypeptide–doxorubicin conjugate nanoparticles that abolish tumours after a single injection
-
Self-assembling peptide-polymer hydrogels designed from the coiled coil region of fibrin.
-
Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation.
-
Self-cleavable stimulus responsive tags for protein purification without chromatography.
-
Separation of Peptides with Polyionic Nanosponges for MALDI-MS Analysis
-
Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2.
-
Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative.
-
Short-term calcitriol administration improves calcium homeostasis in adults with cystic fibrosis.
-
Signal transduction cascades regulating mating, filamentation, and virulence in Cryptococcus neoformans.
-
Significance of complement to the mechanism of action of endotoxin.
-
Simple assay for proteases based on aggregation of stimulus-responsive polypeptides.
-
Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry.
-
Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins.
-
Site-specific phosphorylation and point mutations of telokin modulate its Ca2+-desensitizing effect in smooth muscle.
-
Sites of interaction between rod G-protein alpha-subunit and cGMP-phosphodiesterase gamma-subunit. Implications for the phosphodiesterase activation mechanism.
-
Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trial.
-
Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA.
-
Solvent dependence of intramolecular electron transfer in a helical oligoproline assembly.
-
Somatostatin-like immunoactivity and biological activity is present in Tetrahymena pyriformis, a ciliated protozoan.
-
Sorting of lipids and transmembrane peptides between detergent-soluble bilayers and detergent-resistant rafts.
-
Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets.
-
Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist.
-
Spatiotemporal signalling in plant development.
-
Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction.
-
Specific functions of synaptically localized potassium channels in synaptic transmission at the neocortical GABAergic fast-spiking cell synapse.
-
Specificity and regulation of a synaptic vesicle docking complex.
-
Stable docking of neutralizing human immunodeficiency virus type 1 gp41 membrane-proximal external region monoclonal antibodies 2F5 and 4E10 is dependent on the membrane immersion depth of their epitope regions.
-
Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane.
-
Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model.
-
Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates.
-
Statistical characterization of protein ensembles.
-
Statistical estimation of statistical mechanical models: helix-coil theory and peptide helicity prediction.
-
Stent parameters predict major adverse clinical events and the response to platelet glycoprotein IIb/IIIa blockade: findings of the ESPRIT trial.
-
Stiffness of Protease Sensitive and Cell Adhesive PEG Hydrogels Promotes Neovascularization In Vivo.
-
Stimulus-Responsive Prochelators for Manipulating Cellular Metals.
-
Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery.
-
Storage and mobilization of extracellular matrix proteins during sea urchin development.
-
Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators.
-
Structural analysis of HLA-A2 antigen from immunoselected mutant 8.6.1: further definition of an HLA-A2-specific serological determinant.
-
Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee.
-
Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
-
Structural basis of the intrasteric regulation of myosin light chain kinases.
-
Structural components of avian myeloblastosis virus.
-
Structural components of rna tumor viruses.
-
Structural insights into corepressor recognition by antagonist-bound estrogen receptors.
-
Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.
-
Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors.
-
Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide.
-
Structural studies of amphiphilic 4-helix bundle peptides incorporating designed extended chromophores for nonlinear optical biomolecular materials.
-
Structural transitions accompanying the activation of peptide binding to the endoplasmic reticulum Hsp90 chaperone GRP94.
-
Structure and dynamics of an extended conjugated NLO chromophore within an amphiphilic 4-helix bundle peptide by molecular dynamics simulation.
-
Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
-
Structure of macromolecular aggregates. I. Aggregation-induced conformational changes in polypeptides.
-
Structure of macromolecular aggregates. II. Construction of model membranes from phospholipids and polypeptides.
-
Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D(28K).
-
Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts.
-
Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease.
-
Substrate-bound nerve growth factor promotes neurite growth in peripheral nerve.
-
Substructure of human von Willebrand factor.
-
Subunit structure of fragment D from fibrinogen and cross-linked fibrin.
-
Superior in-hospital and 30-day outcomes with abciximab versus eptifibatide: a contemporary analysis of 495 consecutive percutaneous coronary interventions.
-
Suppression of human interferon-gamma production by a 17 amino acid peptide homologous to the transmembrane envelope protein of retroviruses: evidence for a primary role played by monocytes.
-
Suppressive effect on polyclonal B-cell activation of a synthetic peptide homologous to a transmembrane component of oncogenic retroviruses.
-
Supramolecular peptide vaccines: tuning adaptive immunity.
-
Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy.
-
Surface loop dynamics in adeno-associated virus capsid assembly.
-
Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.
-
Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia.
-
Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides.
-
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds.
-
Synergic effect of OP449 and FTY720 on oral squamous cell carcinoma.
-
Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.
-
Synergy and duality in peptide antibiotic mechanisms.
-
Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist.
-
Synthesis and characterization of fluoropolymeric substrata with immobilized minimal peptide sequences for cell adhesion studies. I.
-
Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor.
-
Synthesis and secretion of gamma-globulin by lymph node cells. VI. Characteristics of the structure of immunoglobulin A and its pattern of secretion by appendix cell suspensions.
-
Synthetic biology: Division of logic labour.
-
Synthetic estrogens suppress granulosa cell progesterone production in vitro.
-
Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys.
-
Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase.
-
T cells as a self-referential, sensory organ.
-
T-cell-directed cancer vaccines: the melanoma model.
-
TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.
-
THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation.
-
Tabletized Supramolecular Assemblies for Sublingual Peptide Immunization.
-
Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents.
-
Targeted Mass Spectrometry-Based Approach for Protein-Ligand Binding Analyses in Complex Biological Mixtures Using a Phenacyl Bromide Modification Strategy.
-
Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts.
-
Targeted drug delivery by thermally responsive polymers.
-
Targeting Akt in cancer therapy.
-
Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy.
-
Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.
-
Targeting cancer stem cells through L1CAM suppresses glioma growth.
-
Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer.
-
Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine.
-
Telomere dysfunction causes alveolar stem cell failure.
-
Temperature sensitive peptides: engineering hyperthermia-directed therapeutics.
-
Temperature triggered self-assembly of polypeptides into multivalent spherical micelles.
-
Temporal spectrum of ischemic complications with percutaneous coronary intervention: the ESPRIT experience.
-
Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor.
-
Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells.
-
The 2004 Biophysical Society-Avanti Award in Lipids address: roles of bilayer structure and elastic properties in peptide localization in membranes.
-
The 2012/2013 ABRF Proteomic Research Group Study: Assessing Longitudinal Intralaboratory Variability in Routine Peptide Liquid Chromatography Tandem Mass Spectrometry Analyses.
-
The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro.
-
The C-terminal linker of Escherichia coli FtsZ functions as an intrinsically disordered peptide.
-
The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue.
-
The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence.
-
The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults.
-
The Dh gene of Drosophila melanogaster encodes a diuretic peptide that acts through cyclic AMP.
-
The N- and C-terminal peptides of hIL8/CXCL8 are ligands for hCXCR1 and hCXCR2.
-
The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients.
-
The SAF-box domain of chromatin protein DEK.
-
The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans.
-
The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation.
-
The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles.
-
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules.
-
The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhage.
-
The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis.
-
The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation.
-
The apolipoprotein-E-mimetic COG112 protects amyloid precursor protein intracellular domain-overexpressing animals from Alzheimer's disease-like pathological features.
-
The backrub motion: how protein backbone shrugs when a sidechain dances.
-
The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif.
-
The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes.
-
The complementary use of glycoprotein IIb/IIIa inhibitors and drug-eluting stents in contemporary percutaneous coronary intervention.
-
The complete genome sequence, organization and affinities of carrot red leaf virus.
-
The crystal structure of a collagen-like polypeptide with 3(S)-hydroxyproline residues in the Xaa position forms a standard 7/2 collagen triple helix.
-
The crystal structure of the collagen-like polypeptide (glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)9 at 1.55 A resolution shows up-puckering of the proline ring in the Xaa position.
-
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.
-
The early glycoprotein IIb/IIIa inhibition in non-ST-segment elevation acute coronary syndrome (EARLY ACS) trial: a randomized placebo-controlled trial evaluating the clinical benefits of early front-loaded eptifibatide in the treatment of patients with non-ST-segment elevation acute coronary syndrome--study design and rationale.
-
The effect of aspirin on endothelial progenitor cell biology: preliminary investigation of novel properties.
-
The effect of chronic twice daily exenatide treatment on β-cell function in new onset type 2 diabetes.
-
The effect of enzymatically degradable poly (ethylene glycol) hydrogels on smooth muscle cell phenotype
-
The effect of fibrin polymerization inhibitors on quantitative measurements of plasma fibrinogen.
-
The effect of plasmin on the subunit structure of human fibrin.
-
The effect of plasmin on the subunit structure of human fibrinogen.
-
The effect of transforming growth factor-beta on follicle-stimulating hormone-induced differentiation of cultured rat granulosa cells.
-
The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties.
-
The enteroinsular axis revisited. A novel role for an incretin.
-
The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation.
-
The final touches make perfect the peptide-MHC class I repertoire.
-
The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis.
-
The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes.
-
The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors.
-
The importance of the preactivation peptide in the two-stage mechanism of human plasminogen activation.
-
The incidence of osteonecrosis of the jaw in patients receiving 5 milligrams of zoledronic acid: data from the health outcomes and reduced incidence with zoledronic acid once yearly clinical trials program.
-
The incretins and beta-cell health: contrasting glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 as a path to understand islet function in diabetes.
-
The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding.
-
The influence of amino acid sequence and functionality on the binding process of peptides onto gold surfaces.
-
The inhibitor-1 C terminus facilitates hormonal regulation of cellular protein phosphatase-1: functional implications for inhibitor-1 isoforms.
-
The kinetics of integrilin limited by obesity: a multicenter randomized pharmacokinetic and pharmacodynamic clinical trial.
-
The localization of the light-harvesting complexes in the intracytoplasmic membranes of Rhodopseudomonas capsulata [proceedings].
-
The messenger and the message: gp96 (GRP94)-peptide interactions in cellular immunity.
-
The molecular organization of asymmetric lipid bilayers and lipid-peptide complexes.
-
The novel alkali tolerance function of tfxG in Sinorhizobium meliloti.
-
The novel apolipoprotein E-based peptide COG1410 improves sensorimotor performance and reduces injury magnitude following cortical contusion injury.
-
The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator-activated receptors.
-
The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding.
-
The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds.
-
The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1.
-
The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome.
-
The relationship between meteorological conditions and index acute coronary events in a global clinical trial.
-
The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets.
-
The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.
-
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse.
-
The structural distribution of cooperative interactions in proteins: analysis of the native state ensemble.
-
The structural polypeptides of equine infections anemia virus.
-
The subunit structures of human plasma and platelet factor XIII (fibrin-stabilizing factor).
-
The suppressive effect of a synthetic retroviral peptide on the human IFN gamma production is abrogated by the combined stimulation with IL-1 and IL-2.
-
The synthesis and secretion of gamma-globulin by lymph node cells. V. The dissociation of the microsome-antibody complex with enzymatically and chemically altered gamma-globulins.
-
The therapeutic effects of SET/I2PP2A inhibitors on canine melanoma.
-
The therapeutic potential of a kallikrein inhibitor for treating hereditary angioedema.
-
The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.
-
The use of glycoprotein IIb/IIIa inhibitor therapy in acute ST-segment elevation myocardial infarction: current practice and future trends.
-
The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation.
-
Thematic review series: lipid posttranslational modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I.
-
Therapeutic value of eptifibatide at community hospitals transferring patients to tertiary referral centers early after admission for acute coronary syndromes. PURSUIT Investigators.
-
Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors.
-
Thermal stability of self-assembled peptide vaccine materials.
-
Thermo-responsive systems for controlled drug delivery
-
Thermodynamic analysis of a hydrophobic binding site: probing the PDZ domain with nonproteinogenic peptide ligands.
-
This paper is the winner of an SFB Award in the Hospital Intern, Residency category: Peptide biomaterials raising adaptive immune responses in wound healing contexts.
-
Three-dimensional biomimetic patterning in hydrogels to guide cellular organization.
-
Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation.
-
Timing of and risk factors for myocardial ischemic events after percutaneous coronary intervention (IMPACT-II). Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis.
-
Timing of glycoprotein IIb/IIIa inhibitor use and outcomes among patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (results from CRUSADE).
-
Tissue and cellular distribution of the extended family of protein kinase C isoenzymes.
-
Tissue-specific expression of the mammalian bombesin gene.
-
Titrating Polyarginine into Nanofibers Enhances Cyclic-Dinucleotide Adjuvanticity in Vitro
and after Sublingual Immunization.
-
To find the road traveled to tumor immunity: the trafficking itineraries of molecular chaperones in antigen-presenting cells.
-
Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells.
-
Topography of a flexible ribonucleoprotein helix: protein-protein contacts in Sendai virus nucleocapsids.
-
Toward Building Protein Force Fields by Residue-Based Systematic Molecular Fragmentation and Neural Network.
-
Towards Raman optical activity calculations of large molecules.
-
Toxicity of expanded polyglutamine-domain proteins in Escherichia coli.
-
Tracking the in vivo fate of recombinant polypeptides by isotopic labeling.
-
Transbilayer peptide sorting between raft and nonraft bilayers: comparisons of detergent extraction and confocal microscopy.
-
Transcriptional down-regulation of tumor necrosis factor-alpha gene expression by a synthetic peptide homologous to retroviral envelope protein.
-
Transendothelial migration enhances integrin-dependent human neutrophil chemokinesis.
-
Transfer of GRP94(Gp96)-associated peptides onto endosomal MHC class I molecules.
-
Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk.
-
Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells.
-
Transient elevation of messenger RNA encoding gastrin-releasing peptide, a putative pulmonary growth factor in human fetal lung.
-
Translating antibody-binding peptides into peptoid ligands with improved affinity and stability.
-
Treatment effects of eptifibatide in planned coronary stent implantation in patients with chronic kidney disease (ESPRIT Trial).
-
Treatment of experimental disseminated candidiasis with cilofungin.
-
Treatment of mechanical aortic valve thrombosis with heparin and eptifibatide.
-
Treatment with a laminin-derived peptide suppresses lupus nephritis.
-
Trefoil factor 3 immunohistochemical characterization of follicular thyroid lesions from tissue microarray.
-
Trials in myocardial infarction.
-
Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution.
-
Tumor Subtype Determines Therapeutic Response to Chimeric Polypeptide Nanoparticle-based Chemotherapy in Pten-deleted Mouse Models of Sarcoma.
-
Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice.
-
Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide.
-
Tunable molecular tension sensors reveal extension-based control of vinculin loading.
-
Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland.
-
ULTRASONIC ATTENUATION MEASUREMENTS IN POLY-L-GLUAMIC ACID SOLUTIONS.
-
Ultrasonic absorption measurements in aqueous solutions of glycine, diglycine, and triglycine.
-
Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers.
-
Unfractionated heparin reduces the anti-platelet effects of abciximab but not eptifibatide during PCI.
-
Unraveling the stability of polypeptide helices: critical role of van der Waals interactions
-
Upstream clopidogrel use and the efficacy and safety of early eptifibatide treatment in patients with acute coronary syndrome: an analysis from the Early Glycoprotein IIb/IIIa Inhibition in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) trial.
-
Upstream use of small-molecule glycoprotein iib/iiia inhibitors in patients with non-ST-segment elevation acute coronary syndromes: a systematic overview of randomized clinical trials.
-
Use of artificial neural networks for the accurate prediction of peptide liquid chromatography elution times in proteome analyses.
-
Use of dominant-negative HrpA mutants to dissect Hrp pilus assembly and type III secretion in Pseudomonas syringae pv. tomato.
-
Use of glycoprotein IIb/IIIa inhibition plus fibrinolysis in acute myocardial infarction.
-
Use of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention: insights from the APEX-AMI trial.
-
Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1.
-
Use of synthetic peptides in primates to induce high-titered neutralizing antibodies and MHC class I-restricted cytotoxic T cells against acquired immunodeficiency syndrome retroviruses: an HLA-based vaccine strategy.
-
Using Zero-Balance Ultrafiltration With Dialysate as a Replacement Solution for Toxin and Eptifibatide Removal on a Dialysis-Dependent Patient During Cardiopulmonary Bypass.
-
Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arrays.
-
Using fluorine nuclear magnetic resonance to probe the interaction of membrane-active peptides with the lipid bilayer.
-
Utilizing the GLP-1 signaling system to treat diabetes: sorting through the pharmacologic approaches.
-
V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.
-
Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes.
-
Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.
-
Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.
-
Vaccine-elicited V3 loop-specific antibodies in rhesus monkeys and control of a simian-human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate envelope.
-
Valency-dependent affinity of bioactive hydroxyapatite-binding dendrons.
-
Validation challenge of density-functional theory for peptides-example of Ac-Phe-Ala5-LysH(+).
-
Vascularization of engineered tissues: approaches to promote angio-genesis in biomaterials.
-
Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules.
-
Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis.
-
Voltage-induced long-range coherent electron transfer through organic molecules.
-
Water adsorption at two unsolvated peptides with a protonated lysine residue: from self-solvation to solvation.
-
Zinc Binding Inhibits Cellular Uptake and Antifungal Activity of Histatin-5 in Candida albicans
.
-
[A transformylation reaction--transfer of an N-formyl residue to amino acids and peptides in nucleophilic groups--as a side reaction of peptide synthesis].
-
[Protein transduction domain peptide mediates delivery to the brain via the blood-brain barrier in Drosophila].
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c-Myc is required for maintenance of glioma cancer stem cells.
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mRNA structure determines specificity of a polyQ-driven phase separation.
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miR-181a is an intrinsic modulator of T cell sensitivity and selection.
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p38 signaling and receptor recycling events in a microfluidic endothelial cell adhesion assay.
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p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling.
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α-Helical coiled-coil peptide materials for biomedical applications.
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Keywords of People
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Alexander, John Hunter Peel,
Professor of Medicine,
Medicine, Cardiology
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Blum, Volker,
Associate Professor in the Department of Mechanical Engineering and Materials Science,
Nicholas Institute-Energy Initiative
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Bobay, Benjamin,
Assistant Professor in Radiology,
Radiology
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Chen, Jun,
Professor of Medicine,
Duke Cancer Institute
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Cianciolo, George James,
Associate Professor Emeritus of Pathology,
Pathology
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Erickson, Harold Paul,
James B. Duke Distinguished Professor Emeritus,
Cell Biology
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Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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James, Michael Lucas,
Associate Professor of Anesthesiology,
Anesthesiology
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Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Integrative Immunobiology
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Laskowitz, Daniel Todd,
Professor of Neurology,
Duke Science & Society
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Milano, Carmelo Alessio,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Surgery, Cardiovascular and Thoracic Surgery
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Moorman, Patricia Gripka,
Professor Emeritus in Family Medicine and Community Health,
Duke Cancer Institute
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Patz Jr., Edward F.,
James and Alice Chen Distinguished Professor of Radiology,
Pathology
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
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Starmer, Charles Franklin,
Professor Emeritus of Computer Science,
Computer Science
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Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology
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Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Integrative Immunobiology