Chemotherapy, Cancer, Regional Perfusion
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Subject Areas on Research
- 3D numerical reconstruction of the hyperthermia induced temperature distribution in human sarcomas using DE-MRI measured tissue perfusion: validation against non-invasive MR temperature measurements.
- A multi-institution experience comparing the clinical and physiologic differences between upper extremity and lower extremity melphalan-based isolated limb infusion.
- A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US.
- A multi-institutional experience of repeat regional chemotherapy for recurrent melanoma of extremities.
- A phase 1 study of systemic ADH-1 in combination with melphalan via isolated limb infusion in patients with locally advanced in-transit malignant melanoma.
- Bevacizumab-induced alterations in vascular permeability and drug delivery: a novel approach to augment regional chemotherapy for in-transit melanoma.
- Burden of disease predicts response to isolated limb infusion with melphalan and actinomycin D in melanoma.
- Carotid artery injections in 40- to 99-g Fischer rats: technical note and evaluation of blood flow by various injection techniques.
- Computed Tomography-Based Limb Volume Measurements for Isolated Limb Infusion in Melanoma.
- Consensus guidelines from The American Society of Peritoneal Surface Malignancies on standardizing the delivery of hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal cancer patients in the United States.
- Current clinical and research approaches to optimizing regional chemotherapy: novel strategies generated through a better understanding of drug pharmacokinetics, drug resistance, and the development of clinically relevant animal models.
- Current trends in regional therapy for melanoma: lessons learned from 225 regional chemotherapy treatments between 1995 and 2010 at a single institution.
- Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: non-colorectal indications.
- Factors predicting toxicity and response following isolated limb infusion for melanoma: An international multi-centre study.
- Future directions in regional treatment strategies for melanoma and sarcoma.
- In-transit melanoma: the role of alkylating-agent resistance in regional therapy.
- International Multicenter Experience of Isolated Limb Infusion for In-Transit Melanoma Metastases in Octogenarian and Nonagenarian Patients.
- Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma.
- Isolated limb infusion as a model to test new agents to treat metastatic melanoma.
- Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion.
- Limb preservation with isolated limb infusion for locally advanced nonmelanoma cutaneous and soft-tissue malignant neoplasms.
- Long-Term Oncologic Outcomes After Isolated Limb Infusion for Locoregionally Metastatic Melanoma: An International Multicenter Analysis.
- Marked variability of melphalan plasma drug levels during regional hyperthermic isolated limb perfusion.
- Minimally invasive intra-arterial regional therapy for metastatic melanoma: isolated limb infusion and percutaneous hepatic perfusion.
- Modest advances in survival for patients with colorectal-associated peritoneal carcinomatosis in the era of modern chemotherapy.
- Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine.
- Modulation of resistance to regional chemotherapy in the extremity melanoma model.
- Oncologic Outcomes After Isolated Limb Infusion for Advanced Melanoma: An International Comparison of the Procedure and Outcomes Between the United States and Australia.
- Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.
- Optimizing melphalan pharmacokinetics in regional melanoma therapy: does correcting for ideal body weight alter regional response or toxicity?
- Optimizing regional infusion treatment strategies for melanoma of the extremities.
- Optimizing regional therapy for melanoma.
- Patterns of recurrence following complete response to regional chemotherapy for in-transit melanoma.
- Pharmacokinetics & drug resistance of melphalan in regional chemotherapy: ILP versus ILI.
- Plasma cytokine analysis in patients with advanced extremity melanoma undergoing isolated limb infusion.
- Predicting disease progression after regional therapy for in-transit melanoma.
- Predictive factors of regional toxicity and serum creatine phosphokinase levels after isolated limb infusion for melanoma: a multi-institutional analysis.
- Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response.
- Prospective multicenter phase II trial of systemic ADH-1 in combination with melphalan via isolated limb infusion in patients with advanced extremity melanoma.
- Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC.
- Quality of life after isolated limb infusion for in-transit melanoma of the extremity.
- Randomized multicenter trial of hyperthermic isolated limb perfusion with melphalan alone compared with melphalan plus tumor necrosis factor: American College of Surgeons Oncology Group Trial Z0020.
- Resection of residual disease after isolated limb infusion (ILI) is equivalent to a complete response after ILI-alone in advanced extremity melanoma.
- Standardizing regional therapy: developing a consensus on optimal utilization of regional chemotherapy treatments in melanoma.
- Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma.
- Temozolomide is a novel regional infusion agent for the treatment of advanced extremity melanoma.
- The role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer with peritoneal surface disease.
- The role of hyperthermia in regional alkylating agent chemotherapy.
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Keywords of People
- Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
- Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Integrative Immunobiology