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Subject Areas on Research
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A comparison of Zn2+- and Ca2+-triggered depolarization of liver mitochondria reveals no evidence of Zn2+-induced permeability transition.
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A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries.
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A metamaterial absorber for the terahertz regime: design, fabrication and characterization.
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A novel approach to maintain gut mucosal integrity using an oral enzyme supplement.
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Achieving high permeability and enhanced selectivity for Angstrom-scale separations using artificial water channel membranes.
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Activation of toll-like receptor 4 is necessary for trauma hemorrhagic shock-induced gut injury and polymorphonuclear neutrophil priming.
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Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating.
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Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver.
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Asymmetrical electrically induced injury of rabbit ventricular myocytes.
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Bacterial-mucosal interactions in inflammatory bowel disease: an alliance gone bad.
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Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria.
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Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.
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Can glutamine turn off the motor that drives systemic inflammation?
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Cellular and molecular biology of the aquaporin water channels.
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Chapter 1 - Tubular liposomes with variable permeability for reconstitution of FtsZ rings.
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Characteristics of GTP-mediated microsomal Ca2+ release.
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Characterization of liposomes containing iodine-125-labeled radiographic contrast agents.
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Cl- and K+ transport in human biliary cell lines.
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Combined T2* and T1 measurements for improved perfusion and permeability studies in high field using dynamic contrast enhancement.
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Comparative permeability of different glioma models to horseradish peroxidase.
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Continuous-flow determination of dialyzable calcium in serum.
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Cytosolic delivery of macromolecules. II. Mechanistic studies with pH-sensitive morpholine lipids.
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Dabigatran abrogates brain endothelial cell permeability in response to thrombin.
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Depression and benign intracranial hypertension.
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Depth of water penetration into lipid bilayers.
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Development of luminescence procedures to evaluate permeation of multi-ring polyaromatic compounds through protective materials.
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Differential actions of PAR2 and PAR1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases.
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Diffusion-weighted and perfusion MR imaging for brain tumor characterization and assessment of treatment response.
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Discovery of the aquaporins and development of the field.
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Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids.
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Dual-Energy CT Imaging of Tumor Liposome Delivery After Gold Nanoparticle-Augmented Radiation Therapy.
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E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer.
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Editorial for "Perfusion and Permeability Magnetic Resonance Imaging (MRI) Predicts Future Cavernous Angioma Hemorrhage and Growth".
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Effect of AQP1 expression level on Co(2) permeability in bovine corneal endothelium.
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Effect of allergic bronchoconstriction on airways epithelial permeability to large polar solutes in the guinea pig.
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Effect of fluid shear stress on the permeability of the arterial endothelium.
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Effect of hydrostatic pressure gradients and Na2EDTA on permeability of human Schlemm's canal cell monolayers.
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Effects of colchicine and cytochalasin B on hypertonicity-induced changes in toad urinary bladder.
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Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer.
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Elasticity, strength, and water permeability of bilayers that contain raft microdomain-forming lipids.
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Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia.
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Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation.
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Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits.
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Factors influencing flux decline during nanofiltration of solutions containing dyes and salts.
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Factors influencing nonoxynol-9 permeation and bioactivity in cervical mucus.
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Fate of antidiuretic hormone water channel proteins after retrieval from apical membrane.
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Feasibility of vitrification as a storage method for tissue-engineered blood vessels.
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Flow permeation analysis of bovine cervical mucus.
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Fluorescence imaging of blood-brain barrier disruption.
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Functional and structural characterization of endosomes from toad bladder epithelial cells.
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Functional reconstitution and characterization of AqpZ, the E. coli water channel protein.
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GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
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Geometry-induced asymmetric diffusion.
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Global burden of irritable bowel syndrome: trends, predictions and risk factors.
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Glucose recovery with bare and hydrogel-coated microdialysis probes: experiment and simulation of temporal effects.
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Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia.
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Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism.
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High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4.
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Highly selective water channel activity measured by voltage clamp: analysis of planar lipid bilayers reconstituted with purified AqpZ.
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Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans.
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Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70.
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In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.
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In vivo characterization of tumor vasculature using iodine and gold nanoparticles and dual energy micro-CT.
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Incorporation of Cellulose Nanocrystals (CNCs) into the Polyamide Layer of Thin-Film Composite (TFC) Nanofiltration Membranes for Enhanced Separation Performance and Antifouling Properties.
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Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism.
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Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice.
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Intestinal permeability and inflammation mediate the association between nutrient density of complementary foods and biochemical measures of micronutrient status in young children: results from the MAL-ED study.
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Investigations into pulsed high-intensity focused ultrasound-enhanced delivery: preliminary evidence for a novel mechanism.
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Japanese encephalitis virus neuropenetrance is driven by mast cell chymase.
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K channel gating by an affinity-switching selectivity filter.
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Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates inflammatory response and homeostasis of spleen and colon in experimental model of Pseudomonas aeruginosa pneumonia.
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Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis.
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Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis.
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Local burn injury impairs epithelial permeability and antimicrobial peptide barrier function in distal unburned skin.
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Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition.
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Materials characterization of the low temperature sensitive liposome (LTSL): effects of the lipid composition (lysolipid and DSPE-PEG2000) on the thermal transition and release of doxorubicin
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Measurement of endothelial permeability to 125I-low density lipoproteins in rabbit arteries by use of en face preparations.
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Mechanistic analysis of electroporation-induced cellular uptake of macromolecules.
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Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores.
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Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus.
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Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold.
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Mitochondria in apoptosis and human disease.
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Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow.
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Modeling the adaptive permeability response of porcine iliac arteries to acute changes in mural shear
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Nano-C60 cytotoxicity is due to lipid peroxidation.
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Nicotinic acetylcholine receptor stimulation impairs epidermal permeability barrier function and recovery and modulates cornified envelope proteins.
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Nitric oxide and differential effects of ATP on mitochondrial permeability transition.
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Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia.
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Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock.
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Peripheral nerve repair with collagen conduits.
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Permeability properties of rat renal lysosomes.
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Pulmonary function, bronchial reactivity, and epithelial permeability are response phenotypes to ozone and develop differentially in healthy humans.
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Quantum-dot-decorated robust transductable bioluminescent nanocapsules
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Regulation of tumor necrosis factor cytotoxicity by calcineurin.
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Release of cytochrome c from liver mitochondria during permeability transition.
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Remobilization of residual non-aqueous phase liquid in porous media by freeze-thaw cycles.
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Robotically handled whole-tissue culture system for the screening of oral drug formulations.
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Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats.
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Significance of lipid composition in a blood-brain barrier-mimetic PAMPA assay.
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Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177).
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Small molecule delivery across a perforated artificial membrane by thermoreversible hydrogel poloxamer 407.
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Solubility of carbon dioxide in lipid bilayer membranes and organic solvents.
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Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle.
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TRPV4 channels augment macrophage activation and ventilator-induced lung injury.
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The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.
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The permeability of the outer layers of limbus and anterior sclera.
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The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.
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The water permeability of lens aquaporin-0 depends on its lipid bilayer environment.
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Transdermal drug delivery enhanced and controlled by erbium:YAG laser: a comparative study of lipophilic and hydrophilic drugs.
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Use of liposomes as carriers for radiation synovectomy.
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Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.
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Water movement during apoptosis: a role for aquaporins in the apoptotic volume decrease (AVD).
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Water permeability and mechanical strength of polyunsaturated lipid bilayers.
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Water permeability of an ovarian antral follicle is predominantly transcellular and mediated by aquaporins.
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Water permeability of aquaporin-4 channel depends on bilayer composition, thickness, and elasticity.
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Water-soluble treatments to enhance glucose permeability of protein-resistant polymer overlayers.
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Weight loss via a low-carbohydrate diet improved the intestinal permeability marker, zonulin, in prostate cancer patients.
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Keywords of People
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Badea, Cristian Tudorel,
Professor in Radiology,
Biomedical Engineering
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Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
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Katz, David F.,
Nello L. Teer, Jr. Distinguished Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering,
Biomedical Engineering