Peyer's Patches

• 

  Subject Areas on Research

  • CD28 is required for germinal center formation. 
  • Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin. 
  • Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. 
  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. 
  • Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. 
  • Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset. 
  • Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes. 
  • Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. 
  • Oral vaccine models: multiple delivery systems employing tetanus toxoid. 
  • Orphan nuclear receptors in T lymphocyte development. 
  • Peyer's patch CD8+ memory T cells secrete T helper type 1 and type 2 cytokines and provide help for immunoglobulin secretion. 
  • Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. 
  • TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation. 
  • The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract. 
  • The role of orphan nuclear receptor in thymocyte differentiation and lymphoid organ development. 
  • The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. 
  • Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T cells. 
  • mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium. 
• 

  Keywords of People

  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Immunology