Pharmacokinetics

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  Subject Areas on Research

  • A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor. 
  • A single-nucleotide polymorphism tagging set for human drug metabolism and transport. 
  • Applying pharmacokinetic principles to the management of drug poisoning. 
  • Assessing bioequivalence using genomic data. 
  • COMPARISON IN HUMANS OF THE POTENCY AND PHARMACOKINETICS OF INTRAVENOUSLY INJECTED COCAETHYLENE AND COCAINE 
  • Clinical Pharmacology Studies in Critically Ill Children. 
  • Coronary drug-eluting stent development: issues in trial design. 
  • Correcting for measurement error in individual-level covariates in nonlinear mixed effects models. 
  • Designing drug trials: considerations for pregnant women. 
  • Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review. 
  • Drug-drug interactions in older adults: which ones matter? 
  • Estimation and inference in pharmacokinetic models: the effectiveness of model reformulation and resampling methods for functions of parameters. 
  • Examining outlying subjects and outlying records in bioequivalence trials. 
  • First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies. 
  • Gaps in Drug Dosing for Obese Children: A Systematic Review of Commonly Prescribed Emergency Care Medications. 
  • In vitro bioequivalence testing. 
  • Lessons learned in pediatric clinical research to evaluate safe and effective use of drugs in pregnancy. 
  • Milk thistle nomenclature: why it matters in cancer research and pharmacokinetic studies. 
  • Optimizing biomarker development for clinical studies at the lead optimization stage of drug development 
  • Pharmacokinetic studies in infants using minimal-risk study designs. 
  • Pharmacokinetics and Safety of Micafungin in Infants Supported With Extracorporeal Membrane Oxygenation 
  • Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV-C, 10% (Gamunex, 10%). 
  • Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. 
  • Phase 1 Dose Escalation Study of MEDI-565, a Bispecific T-Cell Engager that Targets Human Carcinoembryonic Antigen, in Patients With Advanced Gastrointestinal Adenocarcinomas 
  • Probabilistic pharmacokinetic models of decompression sickness in humans: Part 2, coupled perfusion-diffusion models. 
  • Sildenafil Pharmacokinetics, Hemodynamic Efficacy and Safety after Stage II Single Ventricle Surgery 
  • Smooth nonparametric maximum likelihood estimation for population pharmacokinetics, with application to quinidine. 
  • The impact of patient compliance on drug concentration profile in multiple doses. 
  • Thrombin: science and application in clinical practice. 
  • Treatment of acute graft-versus-host disease with a nonmitogenic anti-CD3 monoclonal antibody. 
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  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Barker, Piers Christopher Andrew, Professor of Pediatrics, Pediatrics, Cardiology
  • Cohen-Wolkowiez, Michael, Professor of Pediatrics, Pediatrics, Infectious Diseases