Phencyclidine

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  Subject Areas on Research

  • A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells. 
  • A radiohistochemical measure of [3H]TCP binding to the activated NMDA-receptor-gated ion channel in rat brain. 
  • Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel. 
  • Decreased density, but not number, of N-methyl-D-aspartate, glycine and phencyclidine binding sites in hippocampus of senescent rats. 
  • Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. 
  • Effects of chronic phencyclidine on fixed-ratio responding: no relation to neurotransmitter receptor binding in rat cerebral cortex. 
  • Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice. 
  • Elimination of radioactivity from rats after intravenous administration of phenyl-labeled [14C]- or [3H]phencyclidine hydrochloride. 
  • Evidence that zinc inhibits N-methyl-D-aspartate receptor-gated ion channel activation by noncompetitive antagonism of glycine binding. 
  • Field methods for capture and measurement of three monkey species in Costa Rica. 
  • Glycine regulation of the N-methyl-D-aspartate receptor-gated ion channel in hippocampal membranes. 
  • Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus. 
  • Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3. 
  • Monoaminergic dysregulation in glutathione-deficient mice: possible relevance to schizophrenia? 
  • N-methyl-D-aspartate receptor plasticity in kindling: quantitative and qualitative alterations in the N-methyl-D-aspartate receptor-channel complex. 
  • N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis. 
  • NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR. 
  • Phencyclidine and phenylcyclohexene disposition after smoking phencyclidine. 
  • Phencyclidine disposition after intravenous and oral doses. 
  • Phencyclidine disposition in humans after small doses of radiolabeled drug. 
  • Polyamines antagonize N-methyl-D-aspartate-evoked depolarizations, but reduce Mg2+ block. 
  • Pyrolytic characteristics, pharmacokinetics, and bioavailability of smoked heroin, cocaine, phencyclidine, and methamphetamine. 
  • Pyrolytic degradation of heroin, phencyclidine, and cocaine: identification of products and some observations on their metabolism. 
  • Radiohistochemical demonstration of NMDA/glycine-channel activation in rat hippocampus. 
  • Receptors for abused drugs: development and plasticity. 
  • Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine. 
  • Smoking of phencyclidine: disposition in man and stability to pyrolytic conditions. 
  • Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists. 
  • TCP binding: a tool for studying NMDA receptor-mediated neurotransmission in kindling. 
  • The effect of phencyclidine on dopamine metabolism in the mouse brain. 
  • The use of marihuana, ethanol, and other drugs among drivers killed in single-vehicle crashes. 
  • Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel. 
  • Urine pH and phencyclidine excretion.