Phenols

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  Subject Areas on Research

  • Absence of clinically significant neonatal respiratory depression after prolonged maternal propofol administration. 
  • An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. 
  • An improved method of recording rat tracks for measurement of the sciatic functional index of de Medinaceli. 
  • An unusual dienone-phenol rearrangement product formed during the synthesis of mometasone furoate (Sch 32088). 
  • Analysis of alkylphenol ethoxylate metabolites in the aquatic environment using liquid chromatography-electrospray mass spectrometry. 
  • Analysis of medaka cytochrome P450 3A homotropic and heterotropic cooperativity. 
  • Analysis of nonylphenol and nonylphenol ethoxylates in environmental samples by mixed-mode high-performance liquid chromatography-electrospray mass spectrometry. 
  • Applications and societal benefits of plastics. 
  • Associations between polybrominated diphenyl ether (PBDE) flame retardants, phenolic metabolites, and thyroid hormones during pregnancy. 
  • Barnacle Balanus amphitrite adheres by a stepwise cementing process. 
  • Biological assessment of bisphenol A degradation in water following direct photolysis and UV advanced oxidation. 
  • Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H2O2 oxidation. 
  • Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells. 
  • Bisphenol A affects androgen receptor function via multiple mechanisms. 
  • Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter. 
  • Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2. 
  • Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol. 
  • Bovine hepatic fructose 1,6-diphosphatase: -glycerophosphate hydrolysis-evidence for a shared active site. 
  • Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints. 
  • Characterization of the effects of tebufelone on hepatic cytochromes P450 in the beagle dog. 
  • Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins. 
  • Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor. 
  • Comparison of glycoproteins isolated by phenol-water partition of human erythrocyte membranes. 
  • Comparison of machine and manual staining of direct smears for acid-fast bacilli by fluorescence microscopy. 
  • Comparisons of polychromatic and monochromatic UV-based treatments of bisphenol-A in water via toxicity assessments. 
  • Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues. 
  • Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. 
  • Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity. 
  • Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. 
  • Development of an ER action indicator mouse for the study of estrogens, selective ER modulators (SERMs), and Xenobiotics. 
  • Differential biomarker gene and protein expressions in nonylphenol and estradiol-17beta treated juvenile rainbow trout (Oncorhynchus mykiss). 
  • Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta. 
  • Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. 
  • Distribution and fate of neutral alkylphenol ethoxylate metabolites in a sewage-impacted urban estuary. 
  • Effects of diazoxide and beta adrenergic drugs on spontaneous and induced uterine activity in the pregnant baboon. 
  • Effects of genotype and environment on the antioxidant properties of hard winter wheat bran. 
  • Electron-Donating Phenolic and Electron-Accepting Quinone Moieties in Peat Dissolved Organic Matter: Quantities and Redox Transformations in the Context of Peat Biogeochemistry. 
  • Elucidating the links between endocrine disruptors and neurodevelopment. 
  • Endothelial cell growth on oxygen-containing films deposited by radio-frequency plasmas: the role of surface carbonyl groups. 
  • Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917. 
  • Evaluation of selective liver denervation methods. 
  • Gamma-L-glutaminyl-3,4-benzoquinone. Structural studies and enzymatic synthesis. 
  • Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants. 
  • Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner. 
  • Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. 
  • Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. 
  • Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics. 
  • Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies. 
  • Investigation of maternal environmental exposures in association with self-reported preterm birth. 
  • Isolation from the mushroom Agaricus bisporus and chemical synthesis of gamma-L-glutaminyl-4-hydroxybenzene. 
  • Maternal serum bisphenol A levels and risk of pre-eclampsia: a nested case-control study. 
  • Mechanically interlocked calix[4]arene dimers display reversible bond breakage under force. 
  • Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro. 
  • Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish. 
  • Monoamine precursors in the treatment of depression. 
  • Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells. 
  • Polypeptides of avian RNA tumor viruses. 1. Isolation and physical and chemical analysis. 
  • Polypeptides of avian RNA tumor viruses. II. Serological characterization. 
  • Polyphenols increase adhesion between lipid bilayers by forming interbilayer bridges. 
  • Postsynaptic response to stimulation of the Schaffer collaterals with properties similar to those of synaptosomal aspartate release. 
  • Prenatal exposure to environmental phenols and childhood fat mass in the Mount Sinai Children's Environmental Health Study. 
  • Sedimentary nonylphenol contamination in an urbanized, industrialized segment of the Delaware River estuary, USA. 
  • Storage of bluetongue virus-infected Culicoides variipennis. 
  • Studies on photosystem I. Characteristics of "310 material" isolated from spinach chloroplasts. 
  • Studies on the dissociation of flavin adenine dinucleotide from metalloflavoproteins. 
  • The Affinity of Brominated Phenolic Compounds for Human and Zebrafish Thyroid Receptor β: Influence of Chemical Structure. 
  • The G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Nuclear Estrogen Receptor Activity and Stimulates Novel Phosphoproteomic Signatures. 
  • The effect of Kö 1173, a new anticonvulsant agent on experimental cardiac arrhythmias. 
  • The effect of berotec (Th 1165a) on spontaneous and induced uterine activity in the pregnant baboon. 
  • The interaction of polyphenols with bilayers: conditions for increasing bilayer adhesion. 
  • The selection and evaluation of new chelating agents for the treatment of iron overload. 
  • Treatment of spasmodic torticollis with intramuscular phenol injection. 
  • Utilizing a CdTe quantum dots-enzyme hybrid system for the determination of both phenolic compounds and hydrogen peroxide. 
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  Keywords of People

  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship