Phenotype

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  Subject Areas on Research

  • "Model" behavior. 
  • 3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model. 
  • 30-Year Review of Pediatric- and Adult-Onset CVID: Clinical Correlates and Prognostic Indicators. 
  • 3D phenotyping and quantitative trait locus mapping identify core regions of the rice genome controlling root architecture. 
  • 46,XY/46,XY,21q- mosaicism in an infant with neutropenia and properdin deficiency. 
  • A 137-kb deletion within the Potocki-Shaffer syndrome interval on chromosome 11p11.2 associated with developmental delay and hypotonia. 
  • A 4-tiered classification of left ventricular hypertrophy based on left ventricular geometry: the Dallas heart study. 
  • A Genocentric Approach to Discovery of Mendelian Disorders. 
  • A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience. 
  • A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. 
  • A Lennert lymphoma with a helper-T-cell phenotype. 
  • A Multivariate Computational Method to Analyze High-Content RNAi Screening Data. 
  • A Novel Classification of Intrahepatic Cholangiocarcinoma Phenotypes Using Machine Learning Techniques: An International Multi-Institutional Analysis. 
  • A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii. 
  • A PheWAS approach in studying HLA-DRB1*1501. 
  • A Race Against Time-Changing the Natural History of CRIM Negative Infantile Pompe Disease. 
  • A Recurrent De Novo Variant in NACC1 Causes a Syndrome Characterized by Infantile Epilepsy, Cataracts, and Profound Developmental Delay. 
  • A Review and Update on Papillary Immature Metaplasia of the Uterine Cervix: A Distinct Subset of Low-Grade Squamous Intraepithelial Lesion, Proposing a Possible Cell of Origin. 
  • A Segregating Inversion Generates Fitness Variation in Yellow Monkeyflower (Mimulus guttatus). 
  • A Standard Set of Outcome Measures for the Comprehensive Appraisal of Cleft Care. 
  • A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice. 
  • A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. 
  • A biometric latent curve analysis of memory decline in older men of the NAS-NRC twin registry. 
  • A candidate taste receptor gene near a sweet taste locus. 
  • A cardiac arrhythmia syndrome caused by loss of ankyrin-B function. 
  • A case series describing causes of death in pregnant women with sickle cell disease in a low-resource setting. 
  • A chemical mutagenesis approach to identify virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis. 
  • A combination of molecular markers and clinical features improve the classification of pancreatic cysts. 
  • A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4). 
  • A common SCN5A polymorphism attenuates a severe cardiac phenotype caused by a nonsense SCN5A mutation in a Chinese family with an inherited cardiac conduction defect. 
  • A comparison of phenotype definitions for diabetes mellitus. 
  • A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. 
  • A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative. 
  • A comprehensive mutation analysis of RP2 and RPGR in a North American cohort of families with X-linked retinitis pigmentosa. 
  • A computational analysis of nasal vestibule morphologic variabilities on nasal function. 
  • A consensus-based framework for conducting and reporting osteoarthritis phenotype research. 
  • A critical role of STAYGREEN/Mendel's I locus in controlling disease symptom development during Pseudomonas syringae pv tomato infection of Arabidopsis. 
  • A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interactions with the COI1 F-box protein. 
  • A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. 
  • A cytonuclear incompatibility causes anther sterility in Mimulus hybrids. 
  • A deadly game of musical chairs: survival of cells transplanted for myocardial repair. 
  • A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation. 
  • A family study of chronic post-traumatic stress disorder following rape trauma. 
  • A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. 
  • A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer. 
  • A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer. 
  • A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility. 
  • A gain-of-function mutation in a plant disease resistance gene leads to constitutive activation of downstream signal transduction pathways in the snc1 mutant 
  • A genetic approach for studying the physiology of the type 1A (AT1A) angiotensin receptor. 
  • A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. 
  • A genome-wide association study for extremely high intelligence. 
  • A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A. 
  • A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting. 
  • A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p. 
  • A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. 
  • A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. 
  • A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. 
  • A germline mutation at the extreme 3' end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor. 
  • A guide to analysis of mouse energy metabolism. 
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. 
  • A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. 
  • A high-density genome-wide association screen of sporadic ALS in US veterans. 
  • A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype (Shah-Waardenburg syndrome). 
  • A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice. 
  • A human model for multigenic inheritance: phenotypic expression in Hirschsprung disease requires both the RET gene and a new 9q31 locus. 
  • A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene. 
  • A large-scale functional approach to uncover human genes and pathways in Drosophila. 
  • A longitudinal behavioral genetic analysis of the etiology of aggressive and nonaggressive antisocial behavior. 
  • A meta-analysis of CYP2D6 metabolizer phenotype and metoprolol pharmacokinetics. 
  • A murine model of hyperdopaminergic state displays altered respiratory control. 
  • A mutation in Arabidopsis that leads to constitutive expression of systemic acquired resistance. 
  • A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. 
  • A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. 
  • A new path to auxin. 
  • A nonsense mutation due to a single base insertion in the 3'-coding region of glycogen debranching enzyme gene associated with a severe phenotype in a patient with glycogen storage disease type IIIa. 
  • A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat. 
  • A novel dwarfing mutation in a green revolution gene from Brassica rapa. 
  • A novel healthy blood pressure phenotype in the Long Life Family Study. 
  • A novel missense mutation in POMT1 modulates the severe congenital muscular dystrophy phenotype associated with POMT1 nonsense mutations. 
  • A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease. 
  • A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status. 
  • A novel phenotype-based drug-induced liver injury causality assessment tool (DILI-CAT) allows for signal confirmation in early drug development. 
  • A pathogenic variant in the SETBP1 hotspot results in a forme-fruste Schinzel-Giedion syndrome. 
  • A pathway-based classification of human breast cancer. 
  • A patient with duplication (7)(p22.1pter) characterized by array-CGH. 
  • A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials. 
  • A plant genetic network for preventing dysbiosis in the phyllosphere. 
  • A pleiotropic ATM variant (rs1800057 C>G) is associated with risk of multiple cancers. 
  • A public resource facilitating clinical use of genomes. 
  • A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay. 
  • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. 
  • A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder. 
  • A reversible color polyphenism in American peppered moth (Biston betularia cognataria) caterpillars. 
  • A role for Pin1 in mammalian germ cell development and spermatogenesis. 
  • A simple genetic incompatibility causes hybrid male sterility in mimulus. 
  • A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. 
  • A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. 
  • A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. 
  • A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting disease phenotype. 
  • A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry. 
  • A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect. 
  • A system for the direct co-culture of endothelium on smooth muscle cells. 
  • A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes. 
  • A tenascin knockout with a phenotype. 
  • A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. 
  • A toolkit for genetics providers in follow-up of patients with non-diagnostic exome sequencing. 
  • A tripartite interaction among alleles of Notch, Delta, and Enhancer of split during imaginal development of Drosophila melanogaster. 
  • A unique form of mental retardation with a distinctive phenotype maps to Xq26-q27. 
  • A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans. 
  • A whole genome approach for discovering the genetic basis of blood group antigens: independent confirmation for P1 and Xg^a . 
  • A91V is a polymorphism in the perforin gene not causative of an FHLH phenotype. 
  • ADA Deficiency: Evaluation of the Clinical and Laboratory Features and the Outcome. 
  • ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder. 
  • APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors. 
  • APOL1-associated kidney disease in northern Nigerians with treated HIV infection. 
  • APOL1: a case in point for replacing race with genetics. 
  • ATM: genome stability, neuronal development, and cancer cross paths. 
  • Aberrant behaviors of young boys with fragile X syndrome. 
  • Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors. 
  • Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling. 
  • Abnormal vertebral segmentation and the notch signaling pathway in man. 
  • Abscisic acid regulates root elongation through the activities of auxin and ethylene in Arabidopsis thaliana. 
  • Absolute values of dendritic cell subsets in bone marrow, cord blood, and peripheral blood enumerated by a novel method. 
  • Abundant raw material for cis-regulatory evolution in humans. 
  • Accelerated Marfan syndrome model recapitulates established signaling pathways. 
  • Acceptance of high platelet reactivity as a risk factor: now, what do we do about it? 
  • Acetylation phenotype, platelet monoamine oxidase inhibition, and the effectiveness of phenelzine in depression. 
  • Acidic stress promotes a glioma stem cell phenotype. 
  • Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae. 
  • Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae. 
  • Acquisition of a side population fraction augments malignant phenotype in ovarian cancer. 
  • Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. 
  • Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. 
  • Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells. 
  • Active immunization using dendritic cells mixed with tumor cells inhibits the growth of primary breast cancer. 
  • Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice. 
  • Acylcarnitine metabolomic profiles inform clinically-defined major depressive phenotypes. 
  • Adaptive divergence in plasticity in natural populations of Impatiens capensis and its consequences for performance in novel habitats. 
  • Adaptive mechanisms that preserve cardiac function in mice without myoglobin. 
  • Adenosine deaminase deficiency in adults. 
  • Adenosine deaminase deficiency: genotype-phenotype correlations based on expressed activity of 29 mutant alleles. 
  • Adjusting phenotypes via within- and across-generational plasticity. 
  • Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients. 
  • Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. 
  • Adolescent alcohol exposure and persistence of adolescent-typical phenotypes into adulthood: a mini-review. 
  • Adrenal hypoplasia congenita with phenotypic features suggestive of neurofibromatosis type 1 among three African-American brothers. 
  • Advanced imaging techniques for the study of plant growth and development. 
  • Adverse Renal Response to Decongestion in the Obese Phenotype of Heart Failure With Preserved Ejection Fraction. 
  • Airway-specific inducible transgene expression using aerosolized doxycycline. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Alpha-1-antitrypsin globules in hepatocytes of elderly persons with liver disease. 
  • Alterations in HLA-DP and HLA-DQ antigen frequency in patients with dermatitis herpetiformis. 
  • Alterations in slow-twitch muscle phenotype in transgenic mice overexpressing the Ca2+ buffering protein parvalbumin. 
  • Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes. 
  • Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities. 
  • Altered expression of ganglioside phenotypes of human gliomas in vivo and in vitro. 
  • Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma. 
  • Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development. 
  • Altered immune responses in apolipoprotein E-deficient mice. 
  • Altered telomeres in tumors with ATRX and DAXX mutations. 
  • Alternative fuels for cancer cells. 
  • Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice. 
  • Alternative splicing in disease and therapy. 
  • Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. 
  • Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. 
  • Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. 
  • Alzheimer disease with psychosis: excess cognitive impairment is restricted to the misidentification subtype. 
  • Alzheimer's disease and possible gene interaction. 
  • Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936. 
  • Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors. 
  • American Gastroenterological Association Institute Guideline on the Diagnosis and Management of Lynch Syndrome. 
  • Amino acid-level signal-to-noise analysis of incidentally identified variants in genes associated with long QT syndrome during pediatric whole exome sequencing reflects background genetic noise. 
  • Amoeba Predation of Cryptococcus neoformans Results in Pleiotropic Changes to Traits Associated with Virulence. 
  • Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer. 
  • Amplified B lymphocyte CD40 signaling drives regulatory B10 cell expansion in mice. 
  • Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans. 
  • Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery. 
  • An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. 
  • An Ehlers-Danlos syndrome type VIA patient with cystic malformations of the meninges. 
  • An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group. 
  • An HLA class II region restriction fragment length polymorphism (RFLP) in patients with dermatitis herpetiformis: association with HLA-DP phenotype. 
  • An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character. 
  • An analysis of the presence of Fc receptors on bone marrow lymphoblasts in acute lymphoblastic leukemia. A Pediatric Oncology Group study. 
  • An anxiety-like phenotype in mice selectively bred for aggression. 
  • An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. 
  • An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids. 
  • An embryonic system to assess direct and indirect Wnt transcriptional targets. 
  • An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. 
  • An examination of the association between 5-HTTLPR, combat exposure, and PTSD diagnosis among U.S. veterans. 
  • An extensive de novo deletion removing FMR1 in a patient with mental retardation and the fragile X syndrome phenotype. 
  • An important role of l-fucose biosynthesis and protein fucosylation genes in Arabidopsis immunity. 
  • An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer. 
  • An unusual X-linked retinoschisis phenotype and biochemical characterization of the W112C RS1 mutation. 
  • Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. 
  • Analysis of T-cell differentiation antigens in acute lymphatic leukemia using monoclonal antibodies. 
  • Analysis of alcohol-related phenotypes in F2 progeny derived from FH/Wjd and ACI/N rat strains reveals independent measures and sex differences. 
  • Analysis of expression of CD2, CD3, and T cell antigen receptor molecules during early human fetal thymic development. 
  • Analysis of shared heritability in common disorders of the brain. 
  • Anchorage-independent cell growth signature identifies tumors with metastatic potential. 
  • Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury. 
  • Anemia in the elderly: clinical impact and practical diagnosis. 
  • Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. 
  • Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes. 
  • Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells. 
  • Animal models in the research of abdominal aortic aneurysms development. 
  • Animal models of heart failure: a scientific statement from the American Heart Association. 
  • Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. 
  • Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. 
  • Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth. 
  • Annotation of phenotypes using ontologies: a gold standard for the training and evaluation of natural language processing systems. 
  • Anorexia nervosa and autism spectrum disorders: guided investigation of social cognitive endophenotypes. 
  • Antagonistic selection and pleiotropy constrain the evolution of plant chemical defenses. 
  • Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes--a report from the Children's Oncology Group. 
  • Anti-Cortactin Autoantibodies Are Associated With Key Clinical Features in Adult Myositis But Are Rarely Present in Juvenile Myositis. 
  • Antifungal drug resistance evoked via RNAi-dependent epimutations. 
  • Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7. 
  • Antithrombotic therapy in acute coronary syndrome: how far up the coagulation cascade will we go? 
  • Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models. 
  • ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice. 
  • Apolipoprotein E-epsilon 4 frequency in geriatric depression. 
  • Apolipoprotein-1 risk variants and associated kidney phenotypes in an adult HIV cohort in Nigeria. 
  • Applications of high-throughput RNA interference screens to problems in cell and developmental biology. 
  • Applying ecological resistance and resilience to dissect bacterial antibiotic responses. 
  • Aquagenic wrinkling: a unique facial presentation. 
  • Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation. 
  • Arabidopsis SNI1 and RAD51D regulate both gene transcription and DNA recombination during the defense response. 
  • Arabidopsis iba response5 suppressors separate responses to various hormones. 
  • Architecture and plasticity: optimizing plant performance in dynamic environments. 
  • Are mutations in the cystic fibrosis gene important in chronic pancreatitis? 
  • Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects. 
  • Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype. 
  • Artificial intelligence-assisted phenotype discovery of fragile X syndrome in a population-based sample. 
  • Asian age-related macular degeneration phenotyping study: rationale, design and protocol of a prospective cohort study. 
  • Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). 
  • Assays for monitoring cellular immune responses to active immunotherapy of cancer. 
  • Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus. 
  • Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam. 
  • Assessment of genetic relatedness of vaginal isolates of Candida albicans from different geographical origins. 
  • Assessment of liver fibrosis progression and regression by a serological collagen turnover profile. 
  • Association Between Use of the 21-Gene Recurrence Score Assay and Receipt of Chemotherapy Among Medicare Beneficiaries With Early-Stage Breast Cancer, 2005-2009. 
  • Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease. 
  • Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. 
  • Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. 
  • Association of IL6ST (gp130) Polymorphism with Functional Outcome Following Spontaneous Intracerebral Hemorrhage. 
  • Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study. 
  • Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 
  • Association of Metabolic Phenotypes With Coronary Artery Disease and Cardiovascular Events in Patients With Stable Chest Pain. 
  • Association of Neighborhood Disadvantage in Childhood With DNA Methylation in Young Adulthood. 
  • Association of common candidate variants with vascular malformations and intracranial hemorrhage in hereditary hemorrhagic telangiectasia. 
  • Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses. 
  • Association of increased spontaneous mutation rates with high levels of transcription in yeast. 
  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. 
  • Association of methotrexate, rheumatoid arthritis and lymphoma: report of 2 cases and literature review. 
  • Association of mtDNA haplogroup F with healthy longevity in the female Chuang population, China. 
  • Association of of Atrial Fibrillation Clinical Phenotypes With Treatment Patterns and Outcomes: A Multicenter Registry Study. 
  • Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. 
  • Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. 
  • Association test for X-linked QTL in family-based designs. 
  • Associations Between Catecholaminergic and Serotonergic Genes and Persistent Breast Pain Phenotypes After Breast Cancer Surgery. 
  • Associations between HLA-DRB1*0102, HLA-B*5801, and hepatotoxicity during initiation of nevirapine-containing regimens in South Africa. 
  • Associations between imprinted gene differentially methylated regions, appetitive traits and body mass index in children. 
  • Associations between parental broader autism phenotype and child autism spectrum disorder phenotype in the Study to Explore Early Development. 
  • Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients. 
  • Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population. 
  • Associations of osteopontin and NT-proBNP with circulating miRNA levels in acute coronary syndrome. 
  • Associations, populations, and the truth: recommendations for genetic association studies in Arthritis & Rheumatism. 
  • Assortative mating by population of origin in a mechanistic model of admixture. 
  • Asynchrony in individual and subpopulation fecundity stabilizes reproductive output of an alpine plant population. 
  • Atherogenic low density lipoprotein phenotype in long-term survivors of childhood acute lymphoblastic leukemia. 
  • Atrial fibrillation and stroke severity: expanding the mechanistic exemplar, clinical phenotype, and goals of anticoagulant pharmacotherapy. 
  • Autism and the serotonin transporter: the long and short of it. 
  • Autism spectrum disorder in sub-saharan africa: A comprehensive scoping review. 
  • Autoimmune phenotype with type I interferon signature in two brothers with ADA2 deficiency carrying a novel CECR1 mutation. 
  • Autosomal dominantly inherited generalized basaloid follicular hamartoma syndrome: report of a new disease in a North Carolina family. 
  • Autosomal-dominant retinitis pigmentosa associated with an Arg-135-Trp point mutation of the rhodopsin gene. Clinical features and longitudinal observations. 
  • Avian Binocularity and Adaptation to Nocturnal Environments: Genomic Insights from a Highly Derived Visual Phenotype. 
  • Axin2 regulates chondrocyte maturation and axial skeletal development. 
  • B10 cell regulation of health and disease. 
  • BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells. 
  • BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. 
  • BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. 
  • BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning. 
  • Balance of Irgm protein activities determines IFN-gamma-induced host defense. 
  • Balancing different types of actin polymerization at distinct sites: roles for Abelson kinase and Enabled. 
  • Bayesian learning from marginal data in bionetwork models. 
  • Bayesian probit regression model for the diagnosis of pulmonary fibrosis: proof-of-principle. 
  • Bcl-xL is an oncogenic driver in colorectal cancer. 
  • Behavioral comparisons in autistic individuals from multiplex and singleton families. 
  • Behavioral manipulation of the diabetic phenotype in ob/ob mice. 
  • Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion. 
  • Benchmarking association analyses of continuous exposures with RNA-seq in observational studies. 
  • Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. 
  • Bi-allelic KARS1 pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease. 
  • Biallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder. 
  • Biochemical Underpinnings of Immune Cell Metabolic Phenotypes. 
  • Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models. 
  • Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children. 
  • Biological, clinical and population relevance of 95 loci for blood lipids. 
  • Biology of aortic aneurysms and dissections. 
  • Biology of gliomas: potential clinical implications of glioma cellular heterogeneity. 
  • Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study. 
  • Biomarkers reflect differences in osteoarthritis phenotypes of the lumbar spine: the Johnston County Osteoarthritis Project. 
  • Biopsychosocial influence on exercise-induced injury: genetic and psychological combinations are predictive of shoulder pain phenotypes. 
  • Biphenotypic sarcoma with characteristics of both a Ewing sarcoma and a desmoplastic small round cell tumor. 
  • Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer. 
  • Blood group antigens on complement receptor/regulatory proteins. 
  • Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. 
  • Bmp4 is required for the generation of primordial germ cells in the mouse embryo. 
  • Boechera, a model system for ecological genomics. 
  • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. 
  • Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. 
  • Branhamella catarrhalis activates human B lymphocytes following interactions with surface IgD and class I major histocompatibility complex antigens. 
  • Breed Differences in Dog Cognition Associated with Brain-Expressed Genes and Neurological Functions. 
  • Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis. 
  • Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis. 
  • Brief report: differences in multijoint symptomatic osteoarthritis phenotypes by race and sex: the Johnston County Osteoarthritis Project. 
  • Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells. 
  • C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent. 
  • C-terminal deletion of the atrophin-1 protein results in growth retardation but not neurodegeneration in mice. 
  • CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts. 
  • CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. 
  • CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation. 
  • CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells. 
  • CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo. 
  • CD30 expression in acute lymphoblastic leukemia as assessed by flow cytometry analysis. 
  • CD7+, CD4-, CD8- acute leukemia: a syndrome of malignant pluripotent lymphohematopoietic cells. 
  • CD8+ T-cell alveolitis in familial pulmonary alveolar microlithiasis. 
  • CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States. 
  • CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. 
  • CNS location of uterine-related neurons revealed by trans-synaptic tracing with pseudorabies virus and their relation to estrogen receptor-immunoreactive neurons. 
  • CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease. 
  • COMT gene locus: new functional variants. 
  • COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. 
  • CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. 
  • CSGALNACT1-congenital disorder of glycosylation: A mild skeletal dysplasia with advanced bone age. 
  • Ca++-switch induction of RPE differentiation. 
  • Ca2+/calmodulin-based signalling in the regulation of the muscle fibre phenotype and its therapeutic potential via modulation of utrophin A and myostatin expression. 
  • Caenorhabditis elegans beta-G spectrin is dispensable for establishment of epithelial polarity, but essential for muscular and neuronal function. 
  • Caenorhabditis elegans cog-1 locus encodes GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development. 
  • Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. 
  • Calcific Aortic Valve Disease: Part 1--Molecular Pathogenetic Aspects, Hemodynamics, and Adaptive Feedbacks. 
  • Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling. 
  • Calvarial mass as a presenting feature of neurofibromatosis type 2 in a pediatric patient. 
  • Can the Environment have a Genetic Basis? A Case Study of Seedling Establishment in Arabidopsis thaliana. 
  • Cancer as "rejuvenescence". 
  • Candida virulence properties and adverse clinical outcomes in neonatal candidiasis. 
  • Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method and monoclonal antibodies. 
  • Cantú syndrome: report of nine new cases and expansion of the clinical phenotype. 
  • Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. 
  • Cardiac micro-computed tomography for morphological and functional phenotyping of muscle LIM protein null mice. 
  • Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts. 
  • Cardiac phenotype in ATP1A3-related syndromes: A multicenter cohort study. 
  • Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management. 
  • Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects. 
  • Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study. 
  • Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors. 
  • Cardiovascular phenotyping of the mouse heart using a 4D radial acquisition and liposomal Gd-DTPA-BMA. 
  • Cell biology. A fungal Achilles' heel. 
  • Cell surface differentiation antigens of the malignant T cell in Sezary syndrome and mycosis fungoides. 
  • Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair. 
  • Cellular anti-GP120 cytolytic reactivities in HIV-1 seropositive individuals. 
  • Cellular energetics and mitochondrial uncoupling in canine aging. 
  • Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene. 
  • Cerebral Cavernous Malformation: From Mechanism to Therapy. 
  • Challenges in the phenotypic characterisation of patients in genetic studies of coronary artery disease. 
  • Changes in protein function underlie the disease spectrum in patients with CHIP mutations. 
  • Characteristics of alloreactive rat T cell lines established from low and high rejecting orthotopic liver transplants. 
  • Characterization and Functional Phenotyping of Renal Immune Cells via Flow Cytometry. 
  • Characterization and immunotherapeutic potential of gammadelta T-cells in patients with glioblastoma. 
  • Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes. 
  • Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo. 
  • Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope. 
  • Characterization of additional components of the environmental pH-sensing complex in the pathogenic fungus Cryptococcus neoformans. 
  • Characterization of alcohol-induced filamentous growth in Saccharomyces cerevisiae. 
  • Characterization of cis-regulatory regions responsible for developmental regulation of the gibberellin biosynthetic gene GA1 in Arabidopsis thaliana 
  • Characterization of cytotoxic cells generated from in vitro cultures of murine bone marrow cells. 
  • Characterization of de novo duplications in eight patients by using fluorescence in situ hybridization with chromosome-specific DNA libraries. 
  • Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. 
  • Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes. 
  • Characterization of the Obese Phenotype of Heart Failure With Preserved Ejection Fraction: A RELAX Trial Ancillary Study. 
  • Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA. 
  • Characterizing chronic pain phenotypes in multiple sclerosis: a nationwide survey study. 
  • Characterizing phenotypes and outcomes of drug-associated liver injury using electronic medical record data. 
  • Characterizing the phenotype of advanced pelvic organ prolapse. 
  • Chemotherapy characteristics are important predictors of primary prophylactic CSF administration in older patients with breast cancer. 
  • Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology. 
  • Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans. 
  • Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis. 
  • Cholangiocarcinoma: Correlation between Molecular Profiling and Imaging Phenotypes. 
  • Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice. 
  • Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. 
  • Chordin is a modifier of tbx1 for the craniofacial malformations of 22q11 deletion syndrome phenotypes in mouse. 
  • Chromosome 22q11.2 deletion syndrome in African-American patients: a diagnostic challenge. 
  • Chromosome 4q25 variants and biomarkers of myocardial fibrosis in patients with atrial fibrillation. 
  • Chromosome breakage in Drosophila melanogaster induced by a monofunctional alkylating agent (EMS). 
  • Chronic Musculoskeletal Pain is a Nervous System Disorder… Now What? 
  • Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis. 
  • Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease. 
  • Circular RNA RSF1 promotes inflammatory and fibrotic phenotypes of irradiated hepatic stellate cell by modulating miR-146a-5p. 
  • Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide. 
  • Circulating Tumor Cell Phenotyping via High-Throughput Acoustic Separation. 
  • Circulating natural killer cell phenotypes in men and women with major depression. Relation to cytotoxic activity and severity of depression. 
  • Classification and genetic characterization of pattern-forming Bacilli. 
  • Classifying Patients Operated for Spondylolisthesis: A K-Means Clustering Analysis of Clinical Presentation Phenotypes. 
  • Classifying the evolutionary and ecological features of neoplasms. 
  • ClinPhen extracts and prioritizes patient phenotypes directly from medical records to expedite genetic disease diagnosis. 
  • Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins. 
  • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. 
  • Clinical Phenotypes in Patients With Type 2 Diabetes Mellitus: Characteristics, Cardiovascular Outcomes and Treatment Strategies. 
  • Clinical and Molecular Disease Spectrum and Outcomes in Patients with Infantile-Onset Pompe Disease. 
  • Clinical and mutational spectrum of neurofibromatosis type 1-like syndrome. 
  • Clinical characteristics and genotypes in the ADVANCE baseline data set, a comprehensive cohort of US children and adolescents with Pompe disease. 
  • Clinical features and outcome in childhood T-cell leukemia-lymphoma according to stage of thymocyte differentiation: a Pediatric Oncology Group Study. 
  • Clinical genomic testing: getting it right. 
  • Clinical heterogeneity in lymphoedema-distichiasis with FOXC2 truncating mutations. 
  • Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant. 
  • Clinical implications of chronic heart failure phenotypes defined by cluster analysis. 
  • Clinical phenotype and linkage analysis of the congenital fibrosis of the extraocular muscles in an Indian family. 
  • Clinical phenotypes associated with circulating tumor cell enumeration in metastatic castration-resistant prostate cancer. 
  • Clinical phenotypes of castration-resistant prostate cancer. 
  • Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study. 
  • Clinical trials in hospitalized heart failure patients: targeting interventions to optimal phenotypic subpopulations. 
  • Clinical utility of genetic testing in pediatric drug-resistant epilepsy: a pilot study. 
  • Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 1: Pluridisciplinary perspective on their hemodynamics and morphomechanics. 
  • Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 2: Pluridisciplinary perspective on their genetic and molecular origins. 
  • Clinically focused exome sequencing identifies an homozygous mutation that confers DOCK8 deficiency. 
  • Clinicopathologic and cytogenic features of CD34 (My 10)-positive acute nonlymphocytic leukemia. 
  • Clinicopathologic aspects of E rosette negative T cell acute lymphocytic leukemia: a Pediatric Oncology Group study. 
  • Clinicopathological features to distinguish malignant solitary fibrous tumors of the prostate from prostatic stromal tumors. 
  • Cloned mice have an obese phenotype not transmitted to their offspring. 
  • Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus. 
  • Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies. 
  • Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog 
  • Cluster Analysis of Cardiovascular Phenotypes in Patients With Type 2 Diabetes and Established Atherosclerotic Cardiovascular Disease: A Potential Approach to Precision Medicine. 
  • Cnksr2 Loss in Mice Leads to Increased Neural Activity and Behavioral Phenotypes of Epilepsy-Aphasia Syndrome. 
  • Co-occurrence of ADHD and low IQ has genetic origins. 
  • Coat color genetics of Peromyscus: V. California blonde, a new recessive mutation in the deer mouse. 
  • Coated platelets and severe haemophilia A bleeding phenotype: Is there a connection? 
  • Cognitive outcomes and age of detection of severe mucopolysaccharidosis type 1. 
  • Collapsing glomerulopathy: an inflammatory podocytopathy? 
  • Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. 
  • Colonial morphology of staphylococci on Memphis agar: phase variation of slime production, resistance to beta-lactam antibiotics, and virulence. 
  • Colour pattern modification by coldshock in Lepidoptera. 
  • Combination of exome sequencing and immune testing confirms Aicardi-Goutières syndrome type 5 in a challenging pediatric neurology case. 
  • Combinatorial phenotypic signatures distinguish persistent from resolving methicillin-resistant Staphylococcus aureus bacteremia isolates. 
  • Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice. 
  • Comment on "Evolutionary paths underlying flower color variation in Antirrhinum" 
  • Commentary: Patterns and Impact of Electronic Health Records-Defined Depression Phenotypes in Spine Surgery. 
  • Commentary: The Phenotypes of Anxiety and Depression: Analysis of Combined Comorbidity and Treatment in Patients Undergoing Spinal Fusion. 
  • Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia. 
  • Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells. 
  • Common genetic variation and the control of HIV-1 in humans. 
  • Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. 
  • Common human ANK2 variant confers in vivo arrhythmia phenotypes. 
  • Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population. 
  • Common mutation in the PHKA2 gene with variable phenotype in patients with liver phosphorylase b kinase deficiency. 
  • Common variants in Mendelian kidney disease genes and their association with renal function. 
  • Community pharmacists' experience with pharmacogenetic testing. 
  • Comparing age-related macular degeneration phenotype in probands from singleton and multiplex families. 
  • Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children's oncology group. 
  • Comparison of endothelial cell phenotypic markers of late-outgrowth endothelial progenitor cells isolated from patients with coronary artery disease and healthy volunteers. 
  • Comparison of use of phenotypic and genotypic characteristics for identification of species of the anamorph genus Candida and related teleomorph yeast species. 
  • Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects. 
  • Complex genetic interactions in a quantitative trait locus. 
  • Complex trait divergence contributes to environmental niche differentiation in ecological speciation of Boechera stricta. 
  • Complex-trait analysis in plants. 
  • Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. 
  • Computable Phenotype Implementation for a National, Multicenter Pragmatic Clinical Trial: Lessons Learned From ADAPTABLE. 
  • Computational models of cancer cell transport through the microcirculation. 
  • Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene. 
  • Conflicting processes in the evolution of body size and development time. 
  • Congenital microcephaly and chorioretinopathy due to de novo heterozygous KIF11 mutations: five novel mutations and review of the literature. 
  • Conservation and diversification of SCARECROW in maize. 
  • Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. 
  • Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus. 
  • Constitutive salicylic acid-dependent signaling in cpr1 and cpr6 mutants requires PAD4. 
  • Constraint and developmental dissociation of phenotypic integration in a genetically accommodated trait. 
  • Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association. 
  • Control of fibroblast senescence and activation of programmed cell death. 
  • Control of mesenchymal stem cell phenotype and differentiation depending on cell adhesion mechanism. 
  • Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. 
  • Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin. 
  • Conversion of endogenous indole-3-butyric acid to indole-3-acetic acid drives cell expansion in Arabidopsis seedlings. 
  • Cornelia de Lange syndrome in diverse populations. 
  • Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency. 
  • Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism. 
  • Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain. 
  • Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells. 
  • CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer. 
  • Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. 
  • Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice. 
  • Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. 
  • Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defect. 
  • Cryptococcus neoformans gene expression during murine macrophage infection. 
  • Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis. 
  • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. 
  • Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth. 
  • Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype. 
  • Cryptococcus neoformans virulence gene discovery through insertional mutagenesis. 
  • Current views on collapsing glomerulopathy. 
  • Cutaneous T cell lymphoma. Lymphocyte phenotype analysis after anti-thymocyte globulin therapy. 
  • Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes. 
  • Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling. 
  • Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans. 
  • Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis. 
  • Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling. 
  • Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. 
  • Cytokine Gene Polymorphisms Associated With Symptom Clusters in Oncology Patients Undergoing Radiation Therapy. 
  • Cytokinesis proteins Tum and Pav have a nuclear role in Wnt regulation. 
  • Cytokinins can act as suppressors of nitric oxide in Arabidopsis. 
  • Cytotoxicity reactions of chimpanzee antisera with human lymphocyte donors phenotyped or genotyped for HL-A. 
  • D, weak D (Du), and partial D: the molecular story unfolds. 
  • D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study. 
  • DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. 
  • DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. 
  • DNA methyltransferase levels and altered CpG methylation in the total genome and in the GSTP1 gene in human glioma cells transfected with sense and antisense DNA methyltransferase cDNA. 
  • DNA regulatory sequences of the rat tyrosine hydroxylase gene direct correct catecholaminergic cell-type specificity of a human growth hormone reporter in the CNS of transgenic mice causing a dwarf phenotype. 
  • DNA repair phenotype and cancer susceptibility--a mini review. 
  • DNA-based animal models of human disease: from genotype to phenotype. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • Data and animal management software for large-scale phenotype screening. 
  • Data sharing in the undiagnosed diseases network. 
  • Data-driven phenotype discovery of FMR1 premutation carriers in a population-based sample. 
  • De Novo Heterozygous POLR2A Variants Cause a Neurodevelopmental Syndrome with Profound Infantile-Onset Hypotonia. 
  • De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies. 
  • De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype. 
  • De novo CACNA1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism. 
  • De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis. 
  • De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy. 
  • De novo variants in TCF7L2 are associated with a syndromic neurodevelopmental disorder. 
  • De novo variants in the alternative exon 5 of SCN8A cause epileptic encephalopathy. 
  • Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation. 
  • Deciphering the molecular machinery of stem cells: a look at the neoblast gene expression profile. 
  • Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years. 
  • Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study. 
  • Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. 
  • Dedifferentiated parosteal osteosarcoma with giant cell tumor component. 
  • Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk. 
  • Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression. 
  • Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IV. 
  • Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. 
  • Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability. 
  • Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria. 
  • Deficiency of Adenosine Deaminase 2 (DADA2), an Inherited Cause of Polyarteritis Nodosa and a Mimic of Other Systemic Rheumatologic Disorders. 
  • Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance. 
  • Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency. 
  • Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers. 
  • Deficiency of adenosine deaminase 2: a case series revealing clinical manifestations, genotypes and treatment outcomes from Turkey. 
  • Defining the broader phenotype of autism: genetic, brain, and behavioral perspectives. 
  • Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. 
  • Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations. 
  • Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. 
  • Definitions of the phenotypic manifestations of sickle cell disease. 
  • Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells. 
  • Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. 
  • Demonstration of phenotypic abnormalities of thymic epithelium in thymoma including two cases with abundant Langerhans cells. 
  • Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. 
  • Density dependence and population differentiation of genetic architecture in Impatiens capensis in natural environments. 
  • Dental lesions in tumoral calcinosis. 
  • Depression spectrum disease with and without depression in first-degree relatives. 
  • Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control. 
  • Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4. 
  • Dermatitis herpetiformis in two American blacks: HLA type and clinical characteristics. 
  • Design and Implementation of the International Genetics and Translational Research in Transplantation Network. 
  • Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. 
  • Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease. 
  • Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. 
  • Detecting differential growth of microbial populations with Gaussian process regression. 
  • Detecting local haplotype sharing and haplotype association. 
  • Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system. 
  • Detection of differentially abundant cell subpopulations in scRNA-seq data. 
  • Determinants of poliovirus neurovirulence. 
  • Determination of Pain Phenotypes in Knee Osteoarthritis Using Latent Profile Analysis. 
  • Determination of hepatitis B phenotype using biochemical and serological markers. 
  • Development and characterization of an Fv-1-sensitive retrovirus-packaging system: single-hit titration kinetics observed in restrictive cells. 
  • Development and distribution of a human B cell subpopulation identified by the HB-4 monoclonal antibody. 
  • Development and evaluation of a genetic risk score for obesity 
  • Development and evolution of adaptive polyphenisms. 
  • Development and validation of an electronic medical record (EMR)-based computed phenotype of HIV-1 infection. 
  • Development of a contemporary globally diverse HIV viral panel by the EQAPOL program. 
  • Development of an ovarian cancer screening decision model that incorporates disease heterogeneity: implications for potential mortality reduction. 
  • Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation. 
  • Development, Construct Validity, and Predictive Validity of a Continuous Frailty Scale: Results From 2 Large US Cohorts. 
  • Developmental causes of allometry: new models and implications for phenotypic plasticity and evolution. 
  • Developmental constraints in a wild primate. 
  • Developmental mechanisms of threshold evolution in a polyphenic beetle. 
  • Developmental mediation of genetic variation in response to the Fast Track prevention program. 
  • Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel. 
  • Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. 
  • Developmental trajectories of young girls with fragile x syndrome. 
  • Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3. 
  • Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion. 
  • Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria. 
  • Diagnostic and treatment challenges of neuronopathic Gaucher disease: two cases with an intermediate phenotype. 
  • Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry. 
  • Dibutyryl cyclic adenosine monophosphate reduces expression of c-myc during HL-60 differentiation. 
  • Differences in Phenotypes and Liver Transplantation Outcomes by Age Group in Patients with Primary Sclerosing Cholangitis. 
  • Differences in bleeding phenotype and provider interventions in postmenarchal adolescents when compared to adult women with bleeding disorders and heavy menstrual bleeding. 
  • Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: the Johnston County Osteoarthritis project. 
  • Different Phenotypes of Osteoarthritis in the Lumbar Spine Reflected by Demographic and Clinical Characteristics: The Johnston County Osteoarthritis Project. 
  • Different presynaptic roles of synapsins at excitatory and inhibitory synapses. 
  • Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma. 
  • Differential collagen I gene expression in fetal fibroblasts. 
  • Differential expression of p63 isoforms in female reproductive organs. 
  • Differential expression of receptor tyrosine kinases and Shc in fetal and adult rat fibroblasts: toward defining scarless versus scarring fibroblast phenotypes. 
  • Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. 
  • Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior. 
  • Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection. 
  • Differential reversal of lipophilic antifolate resistance in mammalian cells with modulators of the multidrug resistance phenotype. 
  • Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts. 
  • Differentiation of human T lymphocytes: II. Phenotypic difference in skin and blood malignant T-cells in cutaneous T-cell lymphoma. 
  • Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis. 
  • Digital Behavioral Phenotyping Detects Atypical Pattern of Facial Expression in Toddlers with Autism. 
  • Digital Phenotype for Childhood Internalizing Disorders: Less Positive Play and Promise for a Brief Assessment Battery. 
  • Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating. 
  • Direct allelic variation scanning of the yeast genome. 
  • Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. 
  • Discordant and heterogeneous clinically relevant genomic alterations in circulating tumor cells vs plasma DNA from men with metastatic castration resistant prostate cancer. 
  • Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa. 
  • Disentangling the genetics of lean mass. 
  • Dislocating medial triceps and ulnar neuropathy in three generations of one family. 
  • Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. 
  • Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon. 
  • Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production. 
  • Disruption of endosperm development is a major cause of hybrid seed inviability between Mimulus guttatus and Mimulus nudatus. 
  • Disruption of the Ang II type 1 receptor promotes longevity in mice. 
  • Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells. 
  • Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings. 
  • Dissecting the architecture of a quantitative trait locus in yeast. 
  • Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. 
  • Distinct and overlapping roles of two gibberellin 3-oxidases in Arabidopsis development. 
  • Distinct gene expression phenotypes of cells lacking Rb and Rb family members. 
  • Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. 
  • Distribution and medical impact of loss-of-function variants in the Finnish founder population. 
  • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. 
  • Divergent phenotypes in Gaucher disease implicate the role of modifiers. 
  • Divergent selection on flowering time contributes to local adaptation in Mimulus guttatus populations. 
  • Diversity, topographic differentiation, and positional memory in human fibroblasts. 
  • Do convergent developmental mechanisms underlie convergent phenotypes? 
  • Does age impact the obese asthma phenotype? Longitudinal asthma control, airway function, and airflow perception among mild persistent asthmatics. 
  • Does evolutionary theory need a rethink? 
  • Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. 
  • Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. 
  • Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu. 
  • Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population. 
  • Donor-specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population. 
  • Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. 
  • Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity. 
  • Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. 
  • Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye. 
  • Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA. 
  • Drosophila follicle cell amplicons as models for metazoan DNA replication: a cyclinE mutant exhibits increased replication fork elongation. 
  • Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. 
  • Drosophila, genetic screens, and cardiac function. 
  • Drug development for Autism Spectrum Disorder (ASD): Progress, challenges, and future directions. 
  • Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction. 
  • Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. 
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. 
  • Dyspoietic changes associated with hepatosplenic T-cell lymphoma are not a manifestation of a myelodysplastic syndrome: analysis of 25 patients. 
  • E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. 
  • EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity. 
  • Each patient is a research biorepository: informatics-enabled research on surplus clinical specimens via the living BioBank. 
  • Early Life Characteristics and Neurodevelopmental Phenotypes in the Mount Sinai Children's Environmental Health Center. 
  • Early childcare enrollment and childhood wheezing phenotypes. 
  • Early clinical phenotype of late onset Pompe disease: Lessons learned from newborn screening. 
  • Early ethanol consumption predicts relapse-like behavior in adolescent male rats. 
  • Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state. 
  • Early-onset of symptoms and clinical course of Pompe disease associated with the c.-32-13 T > G variant. 
  • Ecological divergence associated with mating system causes nearly complete reproductive isolation between sympatric Mimulus species. 
  • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. 
  • Effect of Genetic African Ancestry on eGFR and Kidney Disease. 
  • Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes. 
  • Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast. 
  • Effect of highly active antiretroviral therapy and thymic transplantation on immunoreconstitution in HIV infection. 
  • Effect of modulating macrophage phenotype on peripheral nerve repair 
  • Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. 
  • Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition. 
  • Effects of covariates: a summary of Group 5 contributions. 
  • Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond. 
  • Efficacy, safety and pharmacokinetics of a new high-purity factor X concentrate in women and girls with hereditary factor X deficiency. 
  • Efficacy, tolerability, and predictors of response to infliximab therapy for Crohn's disease: a large single centre experience. 
  • Efficient estimation of grouped survival models. 
  • Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle. 
  • Elaboration of tubules with active hedgehog drives parenchymal fibrogenesis in gestational alloimmune liver disease. 
  • Electronic health records based phenotyping in next-generation clinical trials: a perspective from the NIH Health Care Systems Collaboratory. 
  • Electroretinographic alterations in the Laurence-Moon-Bardet-Biedl phenotype. 
  • Elevated IgE and atopy in patients treated for early-onset ADA-SCID. 
  • Elevated PTH induces endothelial-to-chondrogenic transition in aortic endothelial cells. 
  • Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis. 
  • Elite swimmers do not exhibit a body mass index trade-off across a wide range of event distances. 
  • Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans. 
  • Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice. 
  • Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. 
  • Energy metabolism in uncoupling protein 3 gene knockout mice. 
  • Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes. 
  • Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor. 
  • Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein. 
  • Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. 
  • Enriching neural stem cell and anti-inflammatory glial phenotypes with electrical stimulation after traumatic brain injury in male rats. 
  • Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels. 
  • Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages). 
  • Environmental and genetic influences on the germination of Arabidopsis thaliana in the field. 
  • Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. 
  • Epidemiologic and genetic aspects of spina bifida and other neural tube defects. 
  • Epidemiology of 21-hydroxylase deficiency in Singapore. 
  • Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone. 
  • Epigenetic Heterogeneity in Human Colorectal Tumors Reveals Preferential Conservation And Evidence of Immune Surveillance. 
  • Epigenetic Signatures of Cigarette Smoking. 
  • Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline. 
  • Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. 
  • Epileptic encephalopathy with features of rapid-onset dystonia Parkinsonism and alternating hemiplegia of childhood: a novel combination phenotype associated with ATP1A3 mutation. 
  • Epistasis and balanced polymorphism influencing complex trait variation. 
  • Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. 
  • Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen. 
  • Epithelial-thymocyte interactions in human thymus. 
  • Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution. 
  • Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum. 
  • Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction. 
  • Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia. 
  • Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. 
  • Estimating the heritability of cognitive traits across dog breeds reveals highly heritable inhibitory control and communication factors. 
  • Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes. 
  • Ethylene directs auxin to control root cell expansion. 
  • EuroPhenome: a repository for high-throughput mouse phenotyping data. 
  • Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis. 
  • Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer. 
  • Evaluation of right and left ventricular diastolic filling. 
  • Evidence for broader autism phenotype characteristics in parents from multiple-incidence autism families. 
  • Evidence for cellular heterogeneity in primary cultures of human orbital fibroblasts. 
  • Evidence for genetic heterogeneity supports clinical differences in congenital myasthenic syndromes. 
  • Evidence for genetic homogeneity in a familial platelet disorder with predisposition to acute myelogenous leukemia (FPD/AML) 
  • Evidence for multiple loci from a genome scan of autism kindreds. 
  • Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system. 
  • Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion. 
  • Evidence of a genetic link between endometriosis and ovarian cancer. 
  • Evidence of adaptive divergence in plasticity: density- and site-dependent selection on shade-avoidance responses in Impatiens capensis. 
  • Evidence that altered amygdala activity in schizophrenia is related to clinical state and not genetic risk. 
  • Evidence that methylation of the FMR-I locus is responsible for variable phenotypic expression of the fragile X syndrome. 
  • Evolution of a polyphenism by genetic accommodation. 
  • Evolution of resistance and progression to disease during clonal expansion of cancer. 
  • Evolutionary characters, phenotypes and ontologies: curating data from the systematic biology literature. 
  • Evolutionary genetics in wild primates: combining genetic approaches with field studies of natural populations. 
  • Evolutionary genetics of plant adaptation. 
  • Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression. 
  • Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates. 
  • Exercise has a disproportionate role in the pathogenesis of arrhythmogenic right ventricular dysplasia/cardiomyopathy in patients without desmosomal mutations. 
  • Exome analysis of two limb-girdle muscular dystrophy families: mutations identified and challenges encountered. 
  • Exomes, Proteins, and Cardiovascular Disease: Making Sense of the Signals. 
  • Expanding the clinical spectrum of late-onset Pompe disease: dilated arteriopathy involving the thoracic aorta, a novel vascular phenotype uncovered. 
  • Expanding the phenotype of late-onset Pompe disease: tongue weakness: a new clinical observation. 
  • Expanding the phenotype of multifocal lymphangioendotheliomatosis with thrombocytopenia. 
  • Experimental models of human carcinogenesis. 
  • Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci. 
  • Explicating heterogeneity of complex traits has strong potential for improving GWAS efficiency. 
  • Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease. 
  • Exploring the genetic basis of chronic periodontitis: a genome-wide association study. 
  • Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin. 
  • Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories. 
  • Expression of differentiation antigens by hybrids of human lymphoblastoid cells. 
  • Expression of ezrin correlates with malignant phenotype of lung cancer, and in vitro knockdown of ezrin reverses the aggressive biological behavior of lung cancer cells. 
  • Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice. 
  • Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice. 
  • Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A. 
  • Expression of multidrug resistance gene mdr1 mRNA in a subset of normal bone marrow cells. 
  • Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans. 
  • Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling. 
  • Extending the Clinical Phenotype of Adenosine Deaminase 2 Deficiency. 
  • Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans. 
  • Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection. 
  • Extracellular Matrix Degradation Products Downregulate Neoplastic Esophageal Cell Phenotype. 
  • Extreme thyroid hormone resistance in a patient with a novel truncated TR mutant. 
  • FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target. 
  • FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. 
  • FGF12 is a candidate Brugada syndrome locus. 
  • FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival. 
  • FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis 
  • Facial pain with localized and widespread manifestations: separate pathways of vulnerability. 
  • Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R. 
  • Factors affecting individual foraging specialization and temporal diet stability across the range of a large "generalist" apex predator. 
  • Factors affecting reproducibility between genome-scale siRNA-based screens. 
  • Familial correlation of retinal vascular caliber in Singapore Chinese. 
  • Familial recurrence of SOX2 anophthalmia syndrome: phenotypically normal mother with two affected daughters. 
  • Familial unilateral Brown syndrome. 
  • Families promote emotional and behavioural resilience to bullying: evidence of an environmental effect. 
  • Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use. 
  • Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. 
  • Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target. 
  • Feasibility of a bilateral 4000-6000 Hz notch as a phenotype for genetic association analysis. 
  • Features for patients. See how they grow. 
  • Fiber-type phenotype of the jaw-closing muscles in Gorilla gorilla, Pan troglodytes, and Pan paniscus: A test of the Frequent Recruitment Hypothesis. 
  • Fidelity in planar cell polarity signalling. 
  • Finding our way through phenotypes. 
  • Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. 
  • Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. 
  • Fine structure mapping and phenotypic analysis of five temperature-sensitive mutations in the second largest subunit of vaccinia virus DNA-dependent RNA polymerase. 
  • First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis. 
  • Five anthocyanin polymorphisms are associated with an R2R3-MYB cluster in Mimulus guttatus (Phrymaceae). 
  • Flying at the head of the pack: Wnt biology in Drosophila. 
  • Focused goodness of fit tests for gene set analyses. 
  • Four polymorphisms in cytochrome P450 1A1 (CYP1A1) gene and breast cancer risk: a meta-analysis. 
  • Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA. 
  • Fragile X phenotype in a patient with a large de novo deletion in Xq27-q28. 
  • Fragments of ATM which have dominant-negative or complementing activity. 
  • Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. 
  • From genotype to phenotype: systems biology meets natural variation. 
  • From lab to field, new approaches to phenotyping root system architecture. 
  • Function of nuclear factor kappaB in pancreatic cancer metastasis. 
  • Functional Characteristics and Phenotypic Plasticity of CD57+PD1- CD4 T Cells and Their Relationship with Transplant Immunosuppression. 
  • Functional analysis of the putative integrin recognition motif on adeno-associated virus 9. 
  • Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. 
  • Functional equivalence of an evolutionarily conserved RNA binding module. 
  • Functional evolution of an anthocyanin pathway enzyme during a flower color transition. 
  • Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB. 
  • Fungal Endophytes of Populus trichocarpa Alter Host Phenotype, Gene Expression, and Rhizobiome Composition. 
  • Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation. 
  • Fungal mating: Candida albicans flips a switch to get in the mood. 
  • Further evidence for the involvement of EFL1 in a Shwachman-Diamond-like syndrome and expansion of the phenotypic features. 
  • Future directions in painful knee osteoarthritis: harnessing complexity in a heterogeneous population. 
  • Fuzzy set analyses of genetic determinants of health and disability status. 
  • G protein signaling and vein graft intimal hyperplasia: reduction of intimal hyperplasia in vein grafts by a Gbetagamma inhibitor suggests a major role of G protein signaling in lesion development. 
  • G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. 
  • G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis. 
  • GAA variants and phenotypes among 1,079 patients with Pompe disease: Data from the Pompe Registry. 
  • GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL. 
  • GERD phenotypes from pH-impedance monitoring predict symptomatic outcomes on prospective evaluation. 
  • GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers. 
  • GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs". 
  • GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos. 
  • GWAS analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis. 
  • Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis. 
  • Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand. 
  • Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. 
  • Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. 
  • Gene expression phenotypes of atherosclerosis. 
  • Gene expression phenotypic models that predict the activity of oncogenic pathways. 
  • Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy. 
  • Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma. 
  • Gene expression profiling for prediction of clinical characteristics of breast cancer. 
  • Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes. 
  • Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. 
  • Gene flow, divergent selection and resistance to introgression in two species of morning glories (Ipomoea). 
  • Gene loss and parallel evolution contribute to species difference in flower color. 
  • Gene loss, adaptive evolution and the co-evolution of plumage coloration genes with opsins in birds. 
  • Gene targeting of a CFTR allele in HT29 human epithelial cells. 
  • Gene-environment interplay and psychopathology: multiple varieties but real effects. 
  • Generation of Tumor Targeted Dendritic Cell Vaccines with Improved Immunogenic and Migratory Phenotype. 
  • Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases. 
  • Generation of ramoplanin-resistant Staphylococcus aureus. 
  • Generators of phenotypic diversity in the evolution of pathogenic microorganisms. 
  • Genes and networks regulating root anatomy and architecture. 
  • Genetic Consequences of Biologically Altered Environments. 
  • Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes. 
  • Genetic Screen Reveals Link between the Maternal Effect Sterile Gene mes-1 and Pseudomonas aeruginosa-induced Neurodegeneration in Caenorhabditis elegans. 
  • Genetic analysis for common complex disease. 
  • Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance. 
  • Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent. 
  • Genetic and environmental factors are associated with serum 25-hydroxyvitamin D concentrations in older African Americans. 
  • Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition. 
  • Genetic and phenotypic changes accompanying the emergence of epizootic subtype IC Venezuelan equine encephalitis viruses from an enzootic subtype ID progenitor. 
  • Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. 
  • Genetic approaches to molecular motors. 
  • Genetic architecture and adaptation of flowering time among environments. 
  • Genetic architecture of divergence: the selfing syndrome in Ipomoea lacunosa. 
  • Genetic architecture of gene expression traits across diverse populations. 
  • Genetic architecture of human pain perception. 
  • Genetic assimilation and accommodation: Models and mechanisms. 
  • Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype. 
  • Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. 
  • Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort. 
  • Genetic association studies; the good, the bad, and the ugly. 
  • Genetic association tests based on ranks (GATOR) for quantitative traits with and without censoring. 
  • Genetic background influences cardiac phenotype in murine chronic kidney disease. 
  • Genetic basis and consequences of niche construction: plasticity-induced genetic constraints on the evolution of seed dispersal in Arabidopsis thaliana. 
  • Genetic basis for divergence in developmental gene expression in two closely related sea urchins. 
  • Genetic basis of adaptive evolution of a polyphenism by genetic accommodation. 
  • Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis. 
  • Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. 
  • Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. 
  • Genetic counseling for fragile x syndrome: updated recommendations of the national society of genetic counselors. 
  • Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. 
  • Genetic determinants of renal transplant outcome: where do we stand? 
  • Genetic divergence causes parallel evolution of flower color in Chilean Mimulus. 
  • Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. 
  • Genetic elucidation of human hyperosmia to isovaleric acid. 
  • Genetic evidence and integration of various data sources for classifying uncertain variants into a single model. 
  • Genetic evidence for hybridization in red oaks (Quercus sect. Lobatae, Fagaceae). 
  • Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population. 
  • Genetic generalized epilepsies. 
  • Genetic heterogeneity in hereditary haemorrhagic telangiectasia: possible correlation with clinical phenotype. 
  • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. 
  • Genetic interactions among regulators of septin organization. 
  • Genetic lesions in diffuse large B-cell lymphomas. 
  • Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy. 
  • Genetic modifiers of the Kv beta2-null phenotype in mice. 
  • Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. 
  • Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. 
  • Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain. 
  • Genetic recombination of poliovirus in a cell-free system. 
  • Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. 
  • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. 
  • Genetic susceptibility to lung cancer: the role of DNA damage and repair. 
  • Genetic transmission of tumoral calcinosis: autosomal dominant with variable clinical expressivity. 
  • Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study. 
  • Genetic variants associated with sepsis. 
  • Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium. 
  • Genetic variants near PDGFRA are associated with corneal curvature in Australians. 
  • Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy. 
  • Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. 
  • Genetic variation associated with childhood and adult stature and risk of MYCN-amplified neuroblastoma. 
  • Genetic variation in IL28B: impact on drug development for chronic hepatitis C infection. 
  • Genetically and epidemiologically related "non-syncytium-inducing" isolates of HIV-1 display heterogeneous growth patterns in macrophages. 
  • Genetically divergent strains of human immunodeficiency virus type 2 use multiple coreceptors for viral entry. 
  • Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa. 
  • Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. 
  • Genetics in heart failure: practical incorporation of this new biologic dimension. 
  • Genetics of pediatric epilepsy. 
  • Genetics of superior growth traits in trees are being mapped but will the faster-growing risk-takers make it in the wild? 
  • Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes. 
  • Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789. 
  • Genome sequencing unveils a regulatory landscape of platelet reactivity. 
  • Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. 
  • Genome-Wide Assessment of Outer Membrane Vesicle Production in Escherichia coli. 
  • Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. 
  • Genome-scale analysis of anti-metabolite directed strain engineering. 
  • Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. 
  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior. 
  • Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. 
  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 
  • Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. 
  • Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. 
  • Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. 
  • Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. 
  • Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients. 
  • Genome-wide association study identifies a novel locus for cannabis dependence. 
  • Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS). 
  • Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci. 
  • Genome-wide association study of bipolar I disorder in the Han Chinese population. 
  • Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients. 
  • Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 
  • Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort. 
  • Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. 
  • Genome-wide direct target analysis reveals a role for SHORT-ROOT in root vascular patterning through cytokinin homeostasis. 
  • Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome. 
  • Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells. 
  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 
  • Genome-wide meta-analyses of smoking behaviors in African Americans. 
  • Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. 
  • Genomewide ancestry and divergence patterns from low-coverage sequencing data reveal a complex history of admixture in wild baboons. 
  • Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. 
  • Genomic analysis of "microphenotypes" in epilepsy. 
  • Genomic approaches for understanding the genetics of complex disease. 
  • Genomic medicine implementation protocols in the PhenX Toolkit: tools for standardized data collection. 
  • Genomic modeling of atherosclerosis in peripheral arterial disease and its variant phenotype in patients with diabetes. 
  • Genomics of Cardiovascular Measures of Autonomic Tone. 
  • Genomics of human health and aging. 
  • Genomics of varicose veins and chronic venous insufficiency. 
  • Genotype is an important determinant of phenotype in adenosine deaminase deficiency. 
  • Genotype, phenotype, and outcomes of nine patients with T-B+NK+ SCID. 
  • Genotype-phenotype correlation in MYH9-related thrombocytopenia. 
  • Genotype-phenotype correlation in two frequent mutations and mutation update in type III glycogen storage disease. 
  • Genotype-phenotype correlation of congenital anomalies in multiple congenital anomalies hypotonia seizures syndrome (MCAHS1)/PIGN-related epilepsy. 
  • Genotype-phenotype correlations and differential diagnosis in autosomal dominant macular disease. 
  • Genotype-phenotype correlations of pheochromocytoma in two large von Hippel-Lindau (VHL) type 2A kindreds with different missense mutations. 
  • Genotype-phenotype study in an FSHD family with a proximal deletion encompassing p13E-11 and D4Z4. 
  • Genotypes and haplotypes of ERCC1 and ERCC2/XPD genes predict levels of benzo[a]pyrene diol epoxide-induced DNA adducts in cultured primary lymphocytes from healthy individuals: a genotype-phenotype correlation analysis. 
  • Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila. 
  • Geometry and airflow dynamics analysis in the nasal cavity during inhalation. 
  • Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study. 
  • Getting biological about the genetics of diabetes. 
  • GiA Roots: software for the high throughput analysis of plant root system architecture. 
  • Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice. 
  • Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. 
  • Glial and neuronal tau pathology in tauopathies: characterization of disease-specific phenotypes and tau pathology progression. 
  • Glioblastoma-related gene mutations and over-expression of functional epidermal growth factor receptors in SKMG-3 glioma cells. 
  • Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains. 
  • Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. 
  • Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia. 
  • Glutathione S-transferase P1 Ile105Val polymorphism and breast cancer risk: convergence and divergence of the two recent meta-analyses. 
  • Glycogen storage disease type I: diagnosis and phenotype/genotype correlation. 
  • Glycogen storage disease type IV: novel mutations and molecular characterization of a heterogeneous disorder. 
  • Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition. 
  • Glycosyl phosphatidylinositol-linked blood group antigens and paroxysmal nocturnal hemoglobinuria. 
  • Going green in Cryptococcus neoformans: the recycling of a selectable drug marker. 
  • Graph auto-encoding brain networks with applications to analyzing large-scale brain imaging datasets. 
  • Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein. 
  • Gut microbiome heritability is nearly universal but environmentally contingent. 
  • Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. 
  • GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China. 
  • HIST1H1E heterozygous protein-truncating variants cause a recognizable syndrome with intellectual disability and distinctive facial gestalt: A study to clarify the HIST1H1E syndrome phenotype in 30 individuals. 
  • HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. 
  • HL-A antigenic loss in malignant transformation. 
  • HLA and Cogan's syndrome. 
  • HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies. 
  • HLA-A and -B allele expression and ability to develop anti-Gag cross-clade responses in subtype C HIV-1-infected Ethiopians. 
  • HLA-B7 associated tuberculin hyporesponsiveness in BCG treated melanoma patients. 
  • HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. 
  • HNF-3 beta as a regulator of floor plate development. 
  • Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis. 
  • Haploinsufficiency of PRR12 causes a spectrum of neurodevelopmental, eye, and multisystem abnormalities. 
  • Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development. 
  • Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure. 
  • Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VIII. Suppressor cell pathways in cutaneous sensitivity responses. 
  • Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry. 
  • Health-related phenotypes and longevity in danish twins. 
  • Heart Failure Clinical Trials in East and Southeast Asia: Understanding the Importance and Defining the Next Steps. 
  • Hedgehog signaling in cholangiocytes. 
  • Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells. 
  • Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation. 
  • Hematopoietic stem cell transplantation rescues the hematological, immunological, and vascular phenotype in DADA2. 
  • Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency. 
  • Hematopoietic stem cells. 
  • Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. 
  • Hemoglobins of Boa constrictor amarali. 
  • Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection. 
  • Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations. 
  • Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH. 
  • Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. 
  • Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working group. 
  • Heritability of functioning in families with schizophrenia in relation to neurocognition. 
  • Heritability of salt sensitivity in black Americans. 
  • Heterogeneity in α-synuclein fibril activity correlates to disease phenotypes in Lewy body dementia. 
  • Heterogeneity of Genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas. 
  • Heterogeneity of antigen expression in advanced epithelial ovarian cancer. 
  • Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism. 
  • Heterogeneity of phenotype in two siblings with adenosine deaminase deficiency. 
  • Heterogeneous association between engrailed-2 and autism in the CPEA network. 
  • Heterogeneous basis of the type VIB form of Ehlers-Danlos syndrome (EDS VIB) that is unrelated to decreased collagen lysyl hydroxylation. 
  • Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance. 
  • Heterozygous variants in MYBPC1 are associated with an expanded neuromuscular phenotype beyond arthrogryposis. 
  • Hierarchical Bayesian mixture modelling for antigen-specific T-cell subtyping in combinatorially encoded flow cytometry studies. 
  • High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype-Phenotype Correlation. 
  • High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. 
  • High prevalence of low HDL-c in the Philippines compared to the US: population differences in associations with diet and BMI. 
  • High prevalence of rare dopamine receptor D4 alleles in children diagnosed with attention-deficit hyperactivity disorder. 
  • High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast. 
  • High-throughput imaging and analysis of root system architecture in Brachypodium distachyon under differential nutrient availability. 
  • High-throughput morphologic phenotyping of the mouse brain with magnetic resonance histology. 
  • High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype. 
  • Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India. 
  • Highly prolific authors in medical science: from charisma to opportunism. 
  • Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation. 
  • HipBA-promoter structures reveal the basis of heritable multidrug tolerance. 
  • Histiocytes in familial and infection-induced/idiopathic hemophagocytic syndromes may exhibit phenotypic differences. 
  • Histocompatibility testing and mixed lymphocyte culture responses in chimpanzee families. 
  • Histologically benign, clinically aggressive: Progressive non-optic pathway pilocytic astrocytomas in adults with NF1. 
  • Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomerase. 
  • Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants. 
  • Hos2p/Set3p deacetylase complex signals secretory stress through the Mpk1p cell integrity pathway. 
  • Host physiological phenotype explains pathogen reservoir potential. 
  • Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice. 
  • Hosts elevate either within-clutch consistency or between-clutch distinctiveness of egg phenotypes in defence against brood parasites. 
  • Hosts of avian brood parasites have evolved egg signatures with elevated information content. 
  • How eco-evolutionary principles can guide tree breeding and tree biotechnology for enhanced productivity. 
  • How frailty models can be used for evaluating longevity limits: taking advantage of an interdisciplinary approach. 
  • How genes influence life span: the biodemography of human survival. 
  • How long can humans live? Lower bound for biological limit of human longevity calculated from Danish twin data using correlated frailty model. 
  • Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. 
  • Human T cells specifically activated against autologous malignant melanoma. 
  • Human T-B lymphoblast hybrids express HLA-DR specificities not expressed by either parent. 
  • Human arteries engineered in vitro. 
  • Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. 
  • Human equivalent of the mouse Nude/SCID phenotype: long-term evaluation of immunologic reconstitution after bone marrow transplantation. 
  • Human erythrocyte acetylcholinesterase bears the Yta blood group antigen and is reduced or absent in the Yt(a-b-) phenotype. 
  • Human erythrocyte antigens. III. Characterization of a panel of murine monoclonal antibodies that react with human erythrocyte and erythroid precursor membranes. 
  • Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene. 
  • Human histocompatibility antigen mutants immunoselected in vitro. Biochemical analysis of a mutant which synthesizes an altered HLA-A2 heavy chain. 
  • Human interleukin-2 and lymphoproliferative (T-helper cell) responses to soluble HLA class I antigens in vitro: I. Specificity for polymorphic domains. 
  • Human leukemia cell lines with comparable receptor binding characteristics but different phenotypic responses to phorbol diesters. 
  • Human melanoma-mediated inhibition of autologous CD4+ helper tumor-infiltrating lymphocyte growth in vitro. 
  • Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9. 
  • Human postnatal CD4- CD8- CD3- thymic T cell precursors differentiate in vitro into T cell receptor delta-bearing cells. 
  • Human red cell antigens. IV. The abnormal sialoglycoprotein of Gerbich-negative red cells. 
  • Human severe combined immunodeficiency: genetic, phenotypic, and functional diversity in one hundred eight infants. 
  • Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations. 
  • Human thymic epithelial cells function as accessory cells for autologous mature thymocyte activation. 
  • Human vitamin D receptor mutations: identification of molecular defects in hypocalcemic vitamin D resistant rickets. 
  • Humoral Reactivity of Renal Transplant-Waitlisted Patients to Cells From GGTA1/CMAH/B4GalNT2, and SLA Class I Knockout Pigs. 
  • Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas. 
  • Hybrid male sterility in Mimulus (Phrymaceae) is associated with a geographically restricted mitochondrial rearrangement. 
  • Hyper-Ia antigen expression on B cells from B6-lpr/lpr mice correlates with manifestations of the autoimmune state. 
  • Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. 
  • Hypercholesterolemia induces oxidant stress that accelerates the ageing of hematopoietic stem cells. 
  • Hyperreactive platelet phenotypes: relationship to altered serotonin transporter number, transport kinetics and intrinsic response to adrenergic co-stimulation. 
  • Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. 
  • Hypodiploidy is associated with a poor prognosis in childhood acute lymphoblastic leukemia. 
  • IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies. 
  • IL-4-STAT6 signal transduction-dependent induction of the clinical phase of Sjögren's syndrome-like disease of the nonobese diabetic mouse. 
  • INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype. 
  • Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. 
  • Identification of Patient-Reported Outcome Phenotypes Among Oncology Patients With Palliative Care Needs. 
  • Identification of a candidate gene for astigmatism. 
  • Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors. 
  • Identification of a mutant DNA polymerase delta in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations. 
  • Identification of a new locus for autosomal recessive Charcot-Marie-Tooth disease with focally folded myelin on chromosome 11p15. 
  • Identification of a nonsense mutation at codon 128 of the Norrie's disease gene in a male infant. 
  • Identification of cis-suppression of human disease mutations by comparative genomics. 
  • Identification of genetic defect of an epilepsy: strategies for therapeutic advances. 
  • Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. 
  • Identification of quantitative trait loci and a candidate locus for freezing tolerance in controlled and outdoor environments in the overwintering crucifer Boechera stricta. 
  • Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. 
  • Identification of two genes causing reinforcement in the Texas wildflower Phlox drummondii. 
  • Identification of variants in CNGA3 as cause for achromatopsia by exome sequencing of a single patient. 
  • Identification of yeast mutants with altered telomere structure. 
  • Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA. 
  • Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. 
  • Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure. 
  • Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration. 
  • Identifying the frailty phenotype: The evidence for good enough. 
  • Imaging and analysis platform for automatic phenotyping and trait ranking of plant root systems. 
  • Imaging genetics and the neurobiological basis of individual differences in vulnerability to addiction. 
  • Immigration and hybridization patterns of yellow and anubis baboons in and around Amboseli, Kenya. 
  • Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL. 
  • Immune phenotypes in individuals positive for antinuclear antibodies: The impact of race and ethnicity. 
  • Immunization of rhesus macaques with a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine elicits protective antibody response against simian human immunodeficiency virus of R5 phenotype. 
  • Immunoglobulin GM and KM allotypes in systemic lupus erythematosus. 
  • Immunohistochemical characterization of neuroendocrine cells in prostate cancer. 
  • Immunologic and clinicopathologic features of common acute lymphoblastic leukemia antigen-positive childhood T-cell leukemia. A Pediatric Oncology Group Study. 
  • Immunologic targeting of FOXP3 in inflammatory breast cancer cells. 
  • Immunophenotypic Shifts in Primary Cutaneous γδ T-Cell Lymphoma Suggest Antigenic Modulation: A Study of Sequential Biopsy Specimens. 
  • Immunophenotypic characterization of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). 
  • Immunoregulatory T cells in cancer immunotherapy. 
  • Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study. 
  • Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study. 
  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. 
  • Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction. 
  • Impact of genotype on clinical course in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated mutation carriers. 
  • Impact of measurement error on testing genetic association with quantitative traits. 
  • Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls. 
  • Impact of the genetic background of transgenic mice upon the formation and timing of choroid plexus papillomas. 
  • Impaired calcium sensing distinguishes primary hyperparathyroidism (PHPT) patients with low bone mineral density. 
  • Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8. 
  • Importance of the Conserved Carboxyl-Terminal CNOT1 Binding Domain to Tristetraprolin Activity In Vivo. 
  • Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies. 
  • Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice. 
  • Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes. 
  • Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report. 
  • In situ and systemic cellular immunity associated with orthotopic rat liver allograft acceptance or rejection. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. 
  • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. 
  • In vitro resistance to thrombin-induced platelet microbicidal protein among clinical bacteremic isolates of Staphylococcus aureus correlates with an endovascular infectious source. 
  • In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir. 
  • In vivo interaction between NPR1 and transcription factor TGA2 leads to salicylic acid-mediated gene activation in Arabidopsis. 
  • In-vivo impaired T helper 1 cell development in submandibular lymph nodes due to IL-12 deficiency following antigen injection into the anterior chamber of the eye. 
  • In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration. 
  • Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. 
  • Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation. 
  • Incomplete Y chromosomes promote magnification in male and female Drosophila. 
  • Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. 
  • Increased hepatic fibrosis and JNK2-dependent liver injury in mice exhibiting hepatocyte-specific deletion of cFLIP. 
  • Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha. 
  • Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta. 
  • Increased replication of non-syncytium-inducing HIV type 1 isolates in monocyte-derived macrophages is linked to advanced disease in infected children. 
  • Increasing evidence for syndromic phenotypes associated with RPGR mutations. 
  • Independent contrasts succeed where ancestor reconstruction fails in a known bacteriophage phylogeny. 
  • Individual variability in tree allometry determines light resource allocation in forest ecosystems: a hierarchical Bayesian approach. 
  • Ineffective esophageal motility phenotypes following fundoplication in gastroesophageal reflux disease. 
  • Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. 
  • Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. 
  • Infiltrating cell phenotypes and patterns associated with hepatic allograft rejection or acceptance. 
  • Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88. 
  • Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. 
  • Inflammatory genes and psychological factors predict induced shoulder pain phenotype. 
  • Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam. 
  • Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice. 
  • Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. 
  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes. 
  • Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells. 
  • Initial Trends in the Use of the 21-Gene Recurrence Score Assay for Patients With Breast Cancer in the Medicare Population, 2005-2009. 
  • Initiation of replication at a mammalian chromosomal origin. 
  • Innate-like Gene Expression of Lung-Resident Memory CD8+ T Cells during Experimental Human Influenza: A Clinical Study. 
  • Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B. 
  • Insight into the phenotype of infants with Pompe disease identified by newborn screening with the common c.-32-13T>G "late-onset" GAA variant. 
  • Insulin Growth Factor Phenotypes in Heart Failure With Preserved Ejection Fraction, an INSPIRE Registry and CATHGEN Study. 
  • Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer. 
  • Integrating molecular technologies for red blood cell typing and compatibility testing into blood centers and transfusion services. 
  • Integrative Physiology: At the Crossroads of Nutrition, Microbiota, Animal Physiology, and Human Health. 
  • Integrative molecular profiling of routine clinical prostate cancer specimens. 
  • Integrin alpha 6 regulates glioblastoma stem cells. 
  • Inter-chromosomal level of genome organization and longevity-related phenotypes in humans. 
  • Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages. 
  • Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression. 
  • Interactions between genotype and depressive symptoms on obesity. 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Interference of nuclear mitochondrial DNA segments in mitochondrial DNA testing resembles biparental transmission of mitochondrial DNA in humans. 
  • Interfrontal angle for characterization of trigonocephaly: part 1: development and validation of a tool for diagnosis of metopic synostosis. 
  • Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. 
  • Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition. 
  • Interplay between septin organization, cell cycle and cell shape in yeast. 
  • Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals. 
  • Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. 
  • Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture. 
  • Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. 
  • Intracardiac transplantation of a mixed population of bone marrow cells improves both regional systolic contractility and diastolic relaxation. 
  • Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations. 
  • Intralingual Administration of AAVrh10-miRSOD1 Improves Respiratory But Not Swallowing Function in a Superoxide Dismutase-1 Mouse Model of Amyotrophic Lateral Sclerosis. 
  • Intraspecific trait variability shapes leaf trait response to altered fire regimes. 
  • Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels. 
  • Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction. 
  • Investigating the importance of anatomical homology for cross-species phenotype comparisons using semantic similarity. - Accepted at pacific symposium on biocomputing, 2016 
  • Investigation of the basis of virulence in serotype A strains of Cryptococcus neoformans from apparently immunocompetent individuals. 
  • In vitro generation of renal tubular epithelial cells from fibroblasts: implications for precision and regenerative medicine in nephrology. 
  • Is FGF13 a major contributor to genetic epilepsy with febrile seizures plus? 
  • Is there a 'regressive phenotype' of Autism Spectrum Disorder associated with the measles-mumps-rubella vaccine? A CPEA Study. 
  • Isolation and characterization of effector-loop mutants of CDC42 in yeast. 
  • Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family. 
  • Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast. 
  • Isolation and functional analysis of the mouse RXRgamma1 gene promoter in anterior pituitary cells. 
  • Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe. 
  • It infects me, it infects me not: phenotypic switching in the fungal pathogen Cryptococcus neoformans. 
  • JAZ repressor proteins are targets of the SCF(COI1) complex during jasmonate signalling. 
  • JNK1 is required to preserve cardiac function in the early response to pressure overload. 
  • Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation. 
  • Joint effect of multiple common SNPs predicts melanoma susceptibility. 
  • Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells. 
  • Karyotypic abnormalities create discordance of germline genotype and cancer cell phenotypes. 
  • Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions. 
  • Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways. 
  • Kilquist syndrome: A novel syndromic hearing loss disorder caused by homozygous deletion of SLC12A2. 
  • Kinase MPK17 and the Peroxisome Division Factor PMD1 Influence Salt-induced Peroxisome Proliferation. 
  • Knocking out lca5 in zebrafish causes cone-rod dystrophy due to impaired outer segment protein trafficking. 
  • Know Me! Unraveling the Riddle of Calcific Aortic Valve Disease by Bioinformatics. 
  • L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectin. 
  • LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target. 
  • Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease. 
  • Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. 
  • Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals. 
  • Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection. 
  • Lansoprazole Is Associated with Worsening Asthma Control in Children with the CYP2C19 Poor Metabolizer Phenotype. 
  • Laparoscopic cholecystectomy in young patients with sickle hemoglobinopathies. 
  • Large and exaggerated sexually selected weapons comprise high proportions of metabolically inexpensive exoskeleton. 
  • Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. 
  • Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. 
  • Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. 
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. 
  • Late onset Pompe Disease in India - Beyond the Caucasian phenotype. 
  • Late-onset ornithine transcarbamylase deficiency in male patients. 
  • Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. 
  • Leaf shape evolution has a similar genetic architecture in three edaphic specialists within the Mimulus guttatus species complex. 
  • Learning phenotype densities conditional on many interacting predictors. 
  • Left bundle-branch block is associated with asimilar dyssynchronous phenotype in heart failure patients with normal and reduced ejection fractions. 
  • Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. 
  • Letter to the editor: Standardization of genetic association studies, pros and cons, reaffirmed. 
  • Leukemias and lymphomas of thymic differentiation. 
  • Leukocyte composition of human breast cancer. 
  • Leukocyte phenotypic changes in an in vitro model of ABO hemolytic transfusion reaction. 
  • Leveraging population information in family-based rare variant association analyses of quantitative traits. 
  • Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. 
  • Life after the screen: making sense of many P-values. 
  • Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. 
  • Ligand-binding residues integrate affinity and efficacy in the NMDA receptor. 
  • Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice. 
  • Linear population allocation by bistable switches in response to transient stimulation. 
  • Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome. 
  • Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q. 
  • Linkage of familial dilated cardiomyopathy with conduction defect and muscular dystrophy to chromosome 6q23. 
  • Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype. 
  • Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions. 
  • Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines. 
  • Lipopolysaccharide bilayer structure: effect of chemotype, core mutations, divalent cations, and temperature. 
  • Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. 
  • Liver injury from nonsteroidal anti-inflammatory drugs in the United States. 
  • Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation. 
  • Longitudinal Cognitive Outcomes of Clinical Phenotypes of Late-Life Depression. 
  • Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study. 
  • Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance. 
  • Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases. 
  • Loss of Drosophila melanogaster p21-activated kinase 3 suppresses defects in synapse structure and function caused by spastin mutations. 
  • Loss of LDAH associated with prostate cancer and hearing loss. 
  • Loss of MPZL3 function causes seborrhoeic dermatitis-like phenotype in mice. 
  • Loss of hPot1 function leads to telomere instability and a cut-like phenotype. 
  • Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds. 
  • Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. 
  • Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells. 
  • Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. 
  • Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK/ERK 1/2 pathway. 
  • Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes. 
  • Lymphocyte subsets in healthy children during the first 5 years of life. 
  • Lyphocyte migration in L-selectin-deficient mice. Altered subset migration and aging of the immune system. 
  • MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program. 
  • MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele. 
  • MPS VI associated ocular phenotypes in an MPS VI murine model and the therapeutic effects of odiparcil treatment. 
  • MRI phenotype is associated with response to doxorubicin and cyclophosphamide neoadjuvant chemotherapy in stage III breast cancer. 
  • MYC/BCL2 double-hit high-grade B-cell lymphoma. 
  • Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients. 
  • Machine learning for phenotyping opioid overdose events. 
  • Machine-learning phenotypic classification of bicuspid aortopathy. 
  • Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases. 
  • Macrophages (histiocytes) in various reactive and inflammatory conditions express different antigenic phenotypes. 
  • Macroporous Dual-compartment Hydrogels for Minimally Invasive Transplantation of Primary Human Hepatocytes. 
  • Magnetic resonance histology for morphologic phenotyping. 
  • Maintenance Poly (ADP-ribose) Polymerase Inhibitor Therapy for Ovarian Cancer: Precision Oncology or One Size Fits All? 
  • Major review: Molecular genetics of primary open-angle glaucoma. 
  • Major-gene resistance to the rust pathogen Coleosporium ipomoeae is common in natural populations of Ipomoea purpurea. 
  • Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein. 
  • Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species. 
  • Manipulating the gut microbiome to decrease uremic toxins. 
  • Manipulation of insulin signaling phenocopies evolution of a host-associated polyphenism. 
  • Manual asymmetry and handedness. 
  • Mapping Effector-Phenotype Landscapes in KRAS-Driven Cancers. 
  • Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders. 
  • Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. 
  • Mapping of antibody specificities to VH gene families. 
  • Mapping phenotypic landscapes using DNA micro-arrays. 
  • Mapping the proteo-genomic convergence of human diseases. 
  • Marital assortment and phenotypic convergence: longitudinal evidence. 
  • Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses. 
  • Massively parallel sequencing of patients with intellectual disability, congenital anomalies and/or autism spectrum disorders with a targeted gene panel. 
  • Maternal immunity and antibodies to dengue virus promote infection and Zika virus-induced microcephaly in fetuses. 
  • Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans. 
  • Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors. 
  • Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts. 
  • Mechanism of hard-nanomaterial clearance by the liver. 
  • Mechanisms for dominance: Adh heterodimer formation in heterozygotes between ENU or X-ray induced null alleles and normal alleles in Drosophila melanogaster. 
  • Mechanisms of self-tolerance and autoimmunity: from whole-animal phenotypes to molecular pathways. 
  • Mechanisms of the proteinuria induced by Rho GTPases. 
  • Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1. 
  • Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. 
  • Medulloblastoma cell-substrate interaction in vitro. 
  • Mekk3 is essential for early embryonic cardiovascular development. 
  • Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. 
  • Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer. 
  • Meniscus cell regional phenotypes: Dedifferentiation and reversal by biomaterial embedding. 
  • MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury. 
  • Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction. 
  • Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype. 
  • Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension. 
  • Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. 
  • Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle. 
  • Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. 
  • Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors. 
  • Metabolic phenotype in the brothers of women with polycystic ovary syndrome. 
  • Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. 
  • Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. 
  • Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants. 
  • Metabolomics: a global biochemical approach to drug response and disease. 
  • Methylation subtypes and large-scale epigenetic alterations in gastric cancer. 
  • Mice lacking Bmp6 function. 
  • Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. 
  • MicroRNAs and Cardiac Regeneration. 
  • Microduplication 22q11.2, an emerging syndrome: clinical, cytogenetic, and molecular analysis of thirteen patients. 
  • Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii. 
  • Minimal barriers to invasion during human colorectal tumor growth. 
  • Minimal phenotype of mice homozygous for a null mutation in the forkhead/winged helix gene, Mf2. 
  • Minimizing the risk of reporting false positives in large-scale RNAi screens. 
  • Minor quantitative trait loci underlie floral traits associated with mating system divergence in Mimulus. 
  • Mismatch repair deficiency in phenotypically normal human cells. 
  • Mismatch repair in replication fidelity, genetic recombination, and cancer biology. 
  • Mismatch repair, genetic stability and tumour avoidance. 
  • Missed diagnoses: Clinically relevant lessons learned through medical mysteries solved by the Undiagnosed Diseases Network. 
  • Missense Variants in RHOBTB2 Cause a Developmental and Epileptic Encephalopathy in Humans, and Altered Levels Cause Neurological Defects in Drosophila. 
  • Mitochondrial Genome Variation Affects Multiple Respiration and Nonrespiration Phenotypes in Saccharomyces cerevisiae. 
  • Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)-like phenotype in a patient with a novel heterozygous POLG mutation. 
  • Mixed-phenotype large granular lymphocytic leukemia: a rare subtype in the large granular lymphocytic leukemia spectrum. 
  • Mobilization of dendritic cells from patients with breast cancer into peripheral blood stem cell leukapheresis samples using Flt-3-Ligand and G-CSF or GM-CSF. 
  • Modeling mutant phenotypes and oscillatory dynamics in the \emph{Saccharomyces cerevisiae} cAMP-PKA pathway 
  • Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. 
  • Modification of COMT-dependent pain sensitivity by psychological stress and sex. 
  • Modifier genes and heart failure. 
  • Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis. 
  • Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. 
  • Modulation of podocyte phenotype in collapsing glomerulopathies. 
  • Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. 
  • Modulation of the transformed and neoplastic phenotype of rat fibroblasts by MHC-I gene expression. 
  • Molecular Aspects of Lifestyle and Environmental Effects in Patients With Diabetes: JACC Focus Seminar. 
  • Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients. 
  • Molecular Tools for Carotenogenesis Analysis in the Mucoral Mucor circinelloides. 
  • Molecular and clinical analyses of Greig cephalopolysyndactyly and Pallister-Hall syndromes: robust phenotype prediction from the type and position of GLI3 mutations. 
  • Molecular and clinical analysis of ALPL in a cohort of patients with suspicion of Hypophosphatasia. 
  • Molecular and genetic approaches for the analysis of C. elegans neuronal development. 
  • Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine. 
  • Molecular basis for elliptocytosis associated with glycophorin C and D deficiency in the Leach phenotype. 
  • Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr). 
  • Molecular basis of a novel adaptation to hypoxic-hypercapnia in a strictly fossorial mole. 
  • Molecular basis of reduced or absent expression of decay-accelerating factor in Cromer blood group phenotypes. 
  • Molecular biology: microRNA is here to stay. 
  • Molecular characterization and investigation of the role of genetic variation in phenotypic variability and response to treatment in a large pediatric Marfan syndrome cohort. 
  • Molecular cloning, nucleotide sequence, and marker exchange mutagenesis of the exo-poly-alpha-D-galacturonosidase-encoding pehX gene of Erwinia chrysanthemi EC16. 
  • Molecular defects underlying the Kell null phenotype. 
  • Molecular determinants of sexual differentiation. 
  • Molecular evidence for arterial repair in atherosclerosis. 
  • Molecular footprint of Medawar's mutation accumulation process in mammalian aging. 
  • Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype. 
  • Molecular mapping of the Cromer blood group Cra and Tca epitopes of decay accelerating factor: toward the use of recombinant antigens in immunohematology. 
  • Molecular pathology of prostate cancer revealed by next-generation sequencing: opportunities for genome-based personalized therapy. 
  • Molecular phenotype of simian virus 40 large T antigen-induced primitive neuroectodermal tumors in four different lines of transgenic mice. 
  • Monolayer absorption of human cytotoxic T cells: evidence for clonality. 
  • Monosynaptic premotor circuit tracing reveals neural substrates for oro-motor coordination. 
  • Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas. 
  • Morphologic phenotyping with MR microscopy: the visible mouse. 
  • Morphological and molecular characterization of variation in common bean (Phaseolus vulgaris L.) germplasm from Azad Jammu and Kashmir, Pakistan. 
  • Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes. 
  • Most of the yeast genomic sequences are not essential for cell growth and division. 
  • Motif module map reveals enforcement of aging by continual NF-kappaB activity. 
  • Mouse models of diabetic nephropathy. 
  • Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology. 
  • Mouse small eye results from mutations in a paired-like homeobox-containing gene. 
  • Moving beyond microbiome-wide associations to causal microbe identification. 
  • MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. 
  • Multi-omics integration in biomedical research - A metabolomics-centric review. 
  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. 
  • Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. 
  • Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. 
  • Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. 
  • Multiethnic polygenic risk scores improve risk prediction in diverse populations. 
  • Multiple Hybridization Events Punctuate the Evolutionary Trajectory of Malassezia furfur. 
  • Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. 
  • Multiple gene segments control the temperature sensitivity and attenuation phenotypes of ca B/Ann Arbor/1/66. 
  • Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis. 
  • Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male. 
  • Multiple loci are associated with white blood cell phenotypes. 
  • Multiple phenotypic changes in mice after knockout of the B3gnt5 gene, encoding Lc3 synthase--a key enzyme in lacto-neolacto ganglioside synthesis. 
  • Multiple quantitative trait loci modify the heart failure phenotype in murine cardiomyopathy. 
  • Multistage designs in the genomic era: providing balance in complex disease studies. 
  • Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness. 
  • Murine bone marrow stromal cells pulsed with homologous tumor-derived exosomes inhibit proliferation of liver cancer cells. 
  • Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract. 
  • Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression. 
  • Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease. 
  • Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles. 
  • Mutation in collagen II alpha 1 isoforms delineates Stickler and Wagner syndrome phenotypes. 
  • Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. 
  • Mutational alteration of the breakage/resealing subunit of bacteriophage T4 DNA topoisomerase confers resistance to antitumor agent m-AMSA. 
  • Mutational analysis of ATP7B and genotype-phenotype correlation in Japanese with Wilson's disease. 
  • Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio. 
  • Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients. 
  • Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K. 
  • Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture. 
  • Mutational spectrum of the oral-facial-digital type I syndrome: a study on a large collection of patients. 
  • Mutations in Fibronectin Cause a Subtype of Spondylometaphyseal Dysplasia with "Corner Fractures". 
  • Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies. 
  • Mutations in Saccharomyces cerevisiae which confer resistance to several amino acid analogs. 
  • Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. 
  • Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. 
  • Mutations in the lysyl hydroxylase 1 gene that result in enzyme deficiency and the clinical phenotype of Ehlers-Danlos syndrome type VI. 
  • Mutations linked to drug resistance, human immunodeficiency virus type 1 biologic phenotype and their association with disease progression in children receiving nucleoside reverse transcriptase inhibitors. 
  • Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing. 
  • Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. 
  • Mutations that Separate the Functions of the Proofreading Subunit of the Escherichia coli Replicase. 
  • Myeloblast phenotypic changes in myelodysplasia. CD34 and CD117 expression abnormalities are common. 
  • Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase. 
  • Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1. 
  • Myosin I contributes to the generation of resting cortical tension. 
  • N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions. 
  • NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism. 
  • NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes. 
  • Nager acrofacial dysostosis. 
  • Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. 
  • Natural killing target antigens as inducers of interferon: studies with an immunoselected, natural killing-resistant human T lymphoblastoid cell line. 
  • Natural selection on a carbon cycling trait drives ecosystem engineering by Sphagnum (peat moss). 
  • Natural variation for drought-response traits in the Mimulus guttatus species complex. 
  • Natural variation in CDC28 underlies morphological phenotypes in an environmental yeast isolate. 
  • Natural variation in MAM within and between populations of Arabidopsis lyrata determines glucosinolate phenotype. 
  • Natural variation, differentiation, and genetic trade-offs of ecophysiological traits in response to water limitation in Brachypodium distachyon and its descendent allotetraploid B. hybridum (Poaceae). 
  • Naturally occurring amino acid polymorphisms in human immunodeficiency virus type 1 (HIV-1) Gag p7(NC) and the C-cleavage site impact Gag-Pol processing by HIV-1 protease. 
  • Near-Absent Levels Of Segregational Variation Suggest Limited Opportunities For The introduction of genetic variation via homeologous chromosome pairing In synthetic neoallotetraploid Mimulus. 
  • Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain-of-function variants R201C and R201H. 
  • Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism. 
  • Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers. 
  • Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons. 
  • Nestling growth and song repertoire size in great reed warblers: evidence for song learning as an indicator mechanism in mate choice. 
  • Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. 
  • Neuroanatomical phenotypes in the reeler mouse. 
  • Neurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms. 
  • Neurocognitive and electrophysiological evidence of altered face processing in parents of children with autism: implications for a model of abnormal development of social brain circuitry in autism. 
  • Neurocognitive development of young children with sickle cell disease through three years of age. 
  • Neurogenic differentiation of murine and human adipose-derived stromal cells. 
  • Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations. 
  • Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684. 
  • New light on an age-old issue. 
  • New or Progressive Multiple Organ Dysfunction Syndrome in Pediatric Severe Sepsis: A Sepsis Phenotype With Higher Morbidity and Mortality. 
  • New tools for studying integration and modularity. 
  • Newborn screening for X-linked adrenoleukodystrophy: evidence summary and advisory committee recommendation. 
  • Niche construction through germination cueing: life-history responses to timing of germination in Arabidopsis thaliana. 
  • Nicotine abstinence genotyping: assessing the impact on smoking cessation clinical trials. 
  • Nitrogen fertilizer application affects lodging resistance by altering secondary cell wall synthesis in japonica rice (Oryza sativa). 
  • NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics in Escherichia coli. 
  • No association of 9p21 with arterial elasticity and retinal microvascular findings. 
  • No energy wasted in the fight against vascular inflammation. 
  • No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA network. 
  • Nomenclature relating to restriction of modified DNA in Escherichia coli. 
  • Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka. 
  • Non-equivalent roles of Drosophila Frizzled and Dfrizzled2 in embryonic wingless signal transduction. 
  • Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits. 
  • Non-linear multidimensional flow cytometry analyses delineate NK cell phenotypes in normal and HIV-infected chimpanzees. 
  • Non-replicating mucosal and systemic vaccines: quantitative and qualitative differences in the Ag-specific CD8(+) T cell population in different tissues. 
  • Nonlethal presentations of CYP26B1-related skeletal anomalies and multiple synostoses syndrome. 
  • Nonlinear developmental processes as sources of dominance. 
  • Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis. 
  • Normal human bone marrow precursors that express terminal deoxynucleotidyl transferase include T-cell precursors and possible lymphoid stem cells. 
  • Normal smooth pursuit eye movements in volunteer subjects meeting schizotypal personality disorder criteria. 
  • Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. 
  • Novel Murine Models of Cerebral Cavernous Malformations. 
  • Novel genetic loci underlying human intracranial volume identified through genome-wide association. 
  • Novel mutations that alter the regulation of sporulation in Bacillus subtilis. Evidence that phosphorylation of regulatory protein SpoOA controls the initiation of sporulation. 
  • Novel variants in SPTAN1 without epilepsy: An expansion of the phenotype. 
  • Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques. 
  • Nucleotide excision repair as a marker for susceptibility to tobacco-related cancers: a review of molecular epidemiological studies. 
  • Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. 
  • OA phenotypes, rather than disease stage, drive structural progression--identification of structural progressors from 2 phase III randomized clinical studies with symptomatic knee OA. 
  • OMIP-006: phenotypic subset analysis of human T regulatory cells via polychromatic flow cytometry. 
  • OX40+ Regulatory T Cells in Cutaneous Squamous Cell Carcinoma Suppress Effector T-Cell Responses and Associate with Metastatic Potential. 
  • Obese-Inflammatory Phenotypes in Heart Failure With Preserved Ejection Fraction. 
  • Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. 
  • Ocular abnormalities in Apert syndrome: genotype/phenotype correlations with fibroblast growth factor receptor type 2 mutations. 
  • Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses. 
  • Ocular phenotype correlations in patients with TWIST versus FGFR3 genetic mutations. 
  • Ocular status of boys with fragile X syndrome: a prospective study. 
  • Oligoclonal CD8 lymphocytes from persons with asymptomatic human immunodeficiency virus (HIV) type 1 infection inhibit HIV-1 replication. 
  • Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3. 
  • On the association between genes and complex traits. 
  • On the causal interpretation of race in regressions adjusting for confounding and mediating variables. 
  • On the evolutionary costs of self-incompatibility: incomplete reproductive compensation due to pollen limitation. 
  • On the origin and evolution of apomixis in Boechera 
  • On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. 
  • Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation. 
  • One tissue, two fates: molecular genetic events that underlie testis versus ovary development. 
  • Only connect: personal genomics and the future of American medicine. 
  • Ontogeny of the human thymus during fetal development. 
  • Ophthalmic phenotypes and the representativeness of twin data for the general population. 
  • Ophthalmologic findings in Cornelia de Lange syndrome: a genotype-phenotype correlation study. 
  • Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis. 
  • Opposite phenotypes of cancer and aging arise from alternative regulation of common signaling pathways. 
  • Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes. 
  • Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression. 
  • Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathy. 
  • Osteoarthritis--a case for personalized health care? 
  • Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype. 
  • Overeating phenotypes in overweight and obese children. 
  • Overexpression of androgen-binding protein/sex hormone-binding globulin in male transgenic mice: tissue distribution and phenotypic disorders. 
  • Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. 
  • Overview of melanoma vaccines and promising approaches. 
  • Oxidative stress survival in a clinical Saccharomyces cerevisiae isolate is influenced by a major quantitative trait nucleotide. 
  • P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study. 
  • P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. 
  • PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. 
  • PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. 
  • PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration. 
  • PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells. 
  • Painful Temporomandibular Disorder: Decade of Discovery from OPPERA Studies. 
  • Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. 
  • Parent-Endorsed Sex Differences in Toddlers with and Without ASD: Utilizing the M-CHAT. 
  • Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice. 
  • Parkin-proven disease: common founders but divergent phenotypes. 
  • Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling. 
  • Partial duplication of 4q12q13 leads to a mild phenotype. 
  • Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors. 
  • Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome. 
  • Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. 
  • Pathophysiological Response to Trauma-Induced Coagulopathy: A Comprehensive Review. 
  • Pathways to PTSD, part II: Sexually abused children. 
  • Patient Phenotypes and SGLT-2 Inhibition in Type 2 Diabetes: Insights From the EMPA-REG OUTCOME Trial. 
  • Patient Phenotypes, Cardiovascular Risk, and Ezetimibe Treatment in Patients After Acute Coronary Syndromes (from IMPROVE-IT). 
  • Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty. 
  • Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression. 
  • Penetrance of mutations in plakophilin-2 among families with arrhythmogenic right ventricular dysplasia/cardiomyopathy. 
  • Performance of a computable phenotype for pediatric asthma using the problem list. 
  • Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration. 
  • Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals. 
  • Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. 
  • Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. 
  • Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. 
  • Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19. 
  • Persistent infection with neurotropic herpes viruses and cognitive impairment. 
  • Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 
  • Personalized targeted therapy for esophageal squamous cell carcinoma. 
  • Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. 
  • Pharmacogenetics studies in STAR*D: strengths, limitations, and results. 
  • Pharmacogenomics in childhood rheumatic disorders: a foundation for future individualized therapy. 
  • Pharmacokinetic-Pharmacodynamic interaction associated with venlafaxine-XR remission in patients with major depressive disorder with history of citalopram / escitalopram treatment failure. 
  • Phase 2 studies of sunitinib and AG013736 in patients with cytokine-refractory renal cell carcinoma. 
  • PhenX RISING: real world implementation and sharing of PhenX measures. 
  • Phenex: ontological annotation of phenotypic diversity. 
  • PhenoDis: a comprehensive database for phenotypic characterization of rare cardiac diseases. 
  • Phenome-Wide Association Study of Severe COVID-19 Genetic Risk Variants. 
  • Phenome-wide association studies (PheWASs) for functional variants. 
  • Phenoscape: Identifying Candidate Genes for Evolutionary Phenotypes. 
  • Phenotype Determines Nanoparticle Uptake by Human Macrophages from Liver and Blood. 
  • Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration. 
  • Phenotype and mutation expansion of the PTPN23 associated disorder characterized by neurodevelopmental delay and structural brain abnormalities. 
  • Phenotype and patterns of inflammatory cell infiltration associated with rejection or acceptance of rat liver allografts. 
  • Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing. 
  • Phenotype of Spirometric Impairment in an Aging Population. 
  • Phenotype of normal spirometry in an aging population. 
  • Phenotype standardization for statin-induced myotoxicity. 
  • Phenotype, Genotype, and Drug Resistance in Subtype C HIV-1 Infection. 
  • Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. 
  • Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone. 
  • Phenotypic Variability Correlates with Clinical Outcome in Cryptococcus Isolates Obtained from Botswanan HIV/AIDS Patients. 
  • Phenotypic abnormalities in macrophages from leptin-deficient, obese mice. 
  • Phenotypic analysis of 303 multiplex families with common epilepsies. 
  • Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts. 
  • Phenotypic and cell cycle properties of human oligodendrocytes in vitro. 
  • Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes. 
  • Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells. 
  • Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc. 
  • Phenotypic and genotypic characteristics of persistent methicillin-resistant Staphylococcus aureus bacteremia in vitro and in an experimental endocarditis model. 
  • Phenotypic and genotypic characterization of Mycobacterium africanum isolates from West Africa. 
  • Phenotypic characterization and ontogeny of components of the human thymic microenvironment. 
  • Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic microenvironment. 
  • Phenotypic characterization of Bbs4 null mice reveals age-dependent penetrance and variable expressivity. 
  • Phenotypic characterization of cutaneous T-cell lymphoma. Use of monoclonal antibodies to compare with other malignant T cells. 
  • Phenotypic characterization of gamma interferon-induced human monocyte polykaryons. 
  • Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells. 
  • Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture. 
  • Phenotypic characterization of murine models of cerebral cavernous malformations. 
  • Phenotypic characterization of skin-infiltrating T cells in cutaneous T-cell lymphoma: comparison with benign cutaneous T-cell infiltrates. 
  • Phenotypic characterization of transgenic Japanese medaka (Oryzias latipes) that express a red fluorescent protein in hepatocytes. 
  • Phenotypic definition of Chiari type I malformation coupled with high-density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15. 
  • Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations. 
  • Phenotypic expansion of KMT2D-related disorder: Beyond Kabuki syndrome. 
  • Phenotypic expression of Bardet-Biedl syndrome in patients homozygous for the common M390R mutation in the BBS1 gene. 
  • Phenotypic heterogeneity in families with age-related macular degeneration. 
  • Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder. 
  • Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. 
  • Phenotypic plasticity and adaptive evolution contribute to advancing flowering phenology in response to climate change. 
  • Phenotypic properties of transmitted founder HIV-1. 
  • Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease. 
  • Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. 
  • Phenotypic signatures arising from unbalanced bacterial growth. 
  • Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7. 
  • Phenotypic stability of Pro347Leu rhodopsin transgenic pigs as indicated by photoreceptor cell degeneration. 
  • Phenotypic subpopulations of macrophages and dendritic cells in human spleen. 
  • Phenotypic variation explains food web structural patterns. 
  • Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines. 
  • Phenotypically linked dichotomy in sea turtle foraging requires multiple conservation approaches. 
  • Phenotyping Tumor-Associated Macrophages. 
  • Phenotyping clinical disorders: lessons learned from pelvic organ prolapse. 
  • Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice. 
  • Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development. 
  • PhyloOncology: Understanding cancer through phylogenetic analysis. 
  • Phylogenetic analyses of eurotiomycetous endophytes reveal their close affinities to Chaetothyriales, Eurotiales, and a new order - Phaeomoniellales. 
  • Phylogeny and evolution of Malagasy plated lizards. 
  • Phylogeny and phenotypic characterization of pathogenic Cryptococcus species and closely related saprobic taxa in the Tremellales. 
  • Physical characteristics of young boys with fragile X syndrome: reasons for difficulties in making a diagnosis in young males. 
  • Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL). 
  • Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration. 
  • Plasticity of plant defense and its evolutionary implications in wild populations of Boechera stricta. 
  • Plasticity of renal erythropoietin-producing cells governs fibrosis. 
  • Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. 
  • Pleiotropic quantitative trait loci contribute to population divergence in traits associated with life-history variation in Mimulus guttatus. 
  • Pleiotropic signaling pathways orchestrate yeast development. 
  • Podocyte-specific knockout of cyclooxygenase 2 exacerbates diabetic kidney disease. 
  • Point mutations alter the mechanical stability of immunoglobulin modules. 
  • Policies and procedures related to testing for weak D phenotypes and administration of Rh immune globulin: results and recommendations related to supplemental questions in the Comprehensive Transfusion Medicine survey of the College of American Pathologists. 
  • Pollen limitation and natural selection on floral characters in the yellow monkeyflower, Mimulus guttatus. 
  • Polycystic ovary syndrome: multiple pathways to a common phenotype? 
  • Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study 
  • Polygenic risk score for disability and insights into disability-related molecular mechanisms. 
  • Polygenic risk scores: pleiotropy and the effect of environment. 
  • Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. 
  • Polymorphic mimicry in Papilio dardanus: mosaic dominance, big effects, and origins. 
  • Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease. 
  • Polymorphisms in NAT2 and GSTP1 are associated with survival in oral and oropharyngeal cancer. 
  • Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. 
  • Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer. 
  • Population Selection and Sequencing of Caenorhabditis elegans Wild Isolates Identifies a Region on Chromosome III Affecting Starvation Resistance. 
  • Population differentiation and plasticity in vegetative ontogeny: effects on life-history expression in Erysimum capitatum (Brassicaceae). 
  • Population perspectives on functional genomic variation in yeast. 
  • Population studies of pepsinogen polymorphism. 
  • Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network. 
  • Positive selection on MMP3 regulation has shaped heart disease risk. 
  • Positively selected Leu-11a (CD16+) cells require the presence of accessory cells or factors for the lysis of herpes simplex virus-infected fibroblasts but not herpes simplex virus-infected Raji. 
  • Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype. 
  • Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans. 
  • Posttranslational regulation of TCR Valpha allelic exclusion during T cell differentiation. 
  • Practical issues in imputation-based association mapping. 
  • Pre-T chronic lymphocytic leukemia with common acute lymphoblastic leukemia antigen. A new immunologic variant. 
  • Pre-clinical cognitive phenotypes for Alzheimer disease: a latent profile approach. 
  • Precisely modeling zero-inflated count phenotype for rare variants. 
  • Preconditioning Vaccine Sites for mRNA-Transfected Dendritic Cell Therapy and Antitumor Efficacy. 
  • Prediagnostic plasma vascular endothelial growth factor levels and risk of prostate cancer. 
  • Predicting the clinical status of human breast cancer by using gene expression profiles. 
  • Predicting the response to simultaneous selection: genetic architecture and physiological constraints. 
  • Predictive factors for response to anti-thymocyte globulin in acquired aplastic anemia. 
  • Prenatal diagnosis of 45,X/46,XX mosaicism and 45,X: implications for postnatal outcome. 
  • Preneoplastic lesions induced by myc and src oncogenes in a heterotopic rat colon. 
  • Prevalence and Associations of Metabolic Syndrome in an Urban High Diabetes Risk Population in a Low/Middle-Income Country. 
  • Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance. 
  • Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse. 
  • Primary Cutaneous T-Cell Lymphomas Showing Gamma-Delta (γδ) Phenotype and Predominantly Epidermotropic Pattern are Clinicopathologically Distinct From Classic Primary Cutaneous γδ T-Cell Lymphomas. 
  • Primary immunodeficiency diseases due to defects in lymphocytes. 
  • Primary immunodeficiency mutation databases. 
  • Primary tumor microRNA signature predicts recurrence and survival in patients with locally advanced esophageal adenocarcinoma. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • Probing the interaction of the multidrug-resistance phenotype with the polypeptide ionophore gramicidin D via functional channel formation. 
  • Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases. 
  • Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2. 
  • Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2. 
  • Properties of procoagulant platelets: defining and characterizing the subpopulation binding a functional prothrombinase. 
  • Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells. 
  • Protection elicited by two glutamine auxotrophs of Mycobacterium tuberculosis and in vivo growth phenotypes of the four unique glutamine synthetase mutants in a murine model. 
  • Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk. 
  • Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression. 
  • Psychotic symptoms in Alzheimer disease: evidence for subtypes. 
  • Pulmonary function, bronchial reactivity, and epithelial permeability are response phenotypes to ozone and develop differentially in healthy humans. 
  • Purification and partial characterization of a human hematopoietic precursor population. 
  • Putting plant resistance traits on the map: a test of the idea that plants are better defended at lower latitudes. 
  • Putting the 2019 CLAD consensus definitions to the test: Two steps forward, one step back? 
  • QTL Mapping in Three Rice Populations Uncovers Major Genomic Regions Associated with African Rice Gall Midge Resistance. 
  • QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. 
  • Quantitative analysis of phenotypic elements augments traditional electroclinical classification of common familial epilepsies. 
  • Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. 
  • Quantitative assessment of autism symptom-related traits in probands and parents: Broader Phenotype Autism Symptom Scale. 
  • Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step. 
  • Quantitative mouse brain phenotyping based on single and multispectral MR protocols. 
  • Quantitative switch in integrin expression accompanies differentiation of F9 cells treated with retinoic acid. 
  • Quantitative trait locus mapping reveals regions of the maize genome controlling root system architecture. 
  • Quiescent phenotype of tumor-specific CD8+ T cells following immunization. 
  • RB regulates transcription of the p21/WAF1/CIP1 gene. 
  • RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila. 
  • RNA stability regulates differential expression of the metastasis protein, osteopontin, in hepatocellular cancer. 
  • ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. 
  • RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures. 
  • Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. 
  • RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development. 
  • Rae1 interaction with NuMA is required for bipolar spindle formation. 
  • RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. 
  • Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). 
  • Random Forests approach for identifying additive and epistatic single nucleotide polymorphisms associated with residual feed intake in dairy cattle. 
  • Range size heritability and diversification patterns in the liverwort genus Radula. 
  • Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. 
  • Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing. 
  • Rapid array mapping of circadian clock and developmental mutations in Arabidopsis 
  • Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes. 
  • Rapid evolution of a polyphenic threshold. 
  • Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans. 
  • Rare and low-frequency coding variants alter human adult height 
  • Rare coding variants and X-linked loci associated with age at menarche. 
  • Rare disease patient matchmaking: development and outcomes of an internet case-finding strategy in the Undiagnosed Diseases Network. 
  • Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis. 
  • Rationale and design of the Duke Electrophysiology Genetic and Genomic Studies (EPGEN) biorepository. 
  • Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype. 
  • Recent advances in immunohematology. 
  • Recent advances in juvenile idiopathic inflammatory myopathies. 
  • Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. 
  • Recessive-interfering mutations in the gibberellin signaling gene SLEEPY1 are rescued by overexpression of its homologue, SNEEZY. 
  • Recognition and specific degradation of bacteriophage T4 mRNAs. 
  • Recombinant human acid alpha-glucosidase enzyme therapy for infantile glycogen storage disease type II: results of a phase I/II clinical trial. 
  • Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells. 
  • Reconstructing genome evolution in historic samples of the Irish potato famine pathogen. 
  • Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. 
  • Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers. 
  • Red blood cell alloimmunization mitigation strategies. 
  • Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes. 
  • Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites. 
  • Redefining heart failure: the utility of genomics. 
  • Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. 
  • Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin. 
  • Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. 
  • Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. 
  • Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. 
  • Reducing environmental bias when measuring natural selection. 
  • Refining phenotype characterization in genetic linkage studies of schizophrenia. 
  • Regional Variations in Alirocumab Dosing Patterns in Patients with Heterozygous Familial Hypercholesterolemia During an Open-Label Extension Study. 
  • Regulation of Gliogenesis by lin-32/Atoh1 in Caenorhabditis elegans. 
  • Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. 
  • Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast. 
  • Regulation of the immune response. II. Concomitant idiotope-specific enhancement and suppression can result in a phenotypically normal response. 
  • Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. 
  • Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. 
  • Rejection of kidney allografts by MHC class I-deficient mice. 
  • Relating Retinal Morphology and Function in Aging and Early to Intermediate Age-related Macular Degeneration Subjects. 
  • Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. 
  • Relationship between antithymocyte globulin, T cell phenotypes, and clinical outcomes in pediatric kidney transplantation. 
  • Relaxed selection in the wild. 
  • Reliability of mutagen sensitivity assay: an inter-laboratory comparison. 
  • Reliable genotypic tropism tests for the major HIV-1 subtypes. 
  • Renal allograft-infiltrating lymphocytes. A prospective analysis of in vitro growth characteristics and clinical relevance. 
  • Repeat polymorphisms within gene regions: phenotypic and evolutionary implications. 
  • Repeated phenotypic changes highlight molecular targets of convergent evolution. 
  • Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity. 
  • Report on the workshop on Hereditary Hemorrhagic Telangiectasia, July 10-11, 1997. 
  • Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. 
  • Requirement for the vasa RNA helicase in gurken mRNA localization. 
  • Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function. 
  • Resource base influences genome-wide DNA methylation levels in wild baboons (Papio cynocephalus). 
  • Response to carpenter and colleagues. 
  • Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice. 
  • Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women. 
  • Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids. 
  • Retinal neovascular markers in retinopathy of prematurity: aetiological implications. 
  • Retinal phenotype of an X-linked pseudo-Usher syndrome in association with the G173R mutation in the RPGR gene. 
  • Retinal phenotypes in patients homozygous for the G1961E mutation in the ABCA4 gene. 
  • Retinal pigment epithelial cells induce foxp3(+) regulatory T cells via membrane-bound TGF-β. 
  • Retinitis pigmentosa associated with rhodopsin mutations: Correlation between phenotypic variability and molecular effects. 
  • Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells. 
  • Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers. 
  • Reversion from deficiency of galactose-1-phosphate uridylytransferase (GALT) in an SV40-transformed human fibroblast line. 
  • Revisiting the Holy Grail: using plant functional traits to understand ecological processes. 
  • Revisiting the association between reading achievement and antisocial behavior: new evidence of an environmental explanation from a twin study. 
  • Rheumatoid arthritis and sterile corneal ulceration. Analysis of tissue immune effector cells and ocular epithelial antigens using monoclonal antibodies. 
  • Rho GTPase inactivation impairs lens growth and integrity. 
  • Ring chromosome 17: phenotype variation by deletion size. 
  • Risk of Prostate Cancer Associated With Familial and Hereditary Cancer Syndromes. 
  • Robust analysis of secondary phenotypes in case-control genetic association studies. 
  • Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 signaling pathway in response to thermal stress. 
  • Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring. 
  • Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. 
  • Role of T-cell activation in salt-sensitive hypertension. 
  • Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564. 
  • Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. 
  • Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. 
  • Roles of wingless in patterning the larval epidermis of Drosophila. 
  • Root traits explain plant species distributions along climatic gradients yet challenge the nature of ecological trade-offs. 
  • SCALEs: multiscale analysis of library enrichment. 
  • SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. 
  • SETD2 histone modifier loss in aggressive GI stromal tumours. 
  • SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence. 
  • SNP-skimming: A fast approach to map loci generating quantitative variation in natural populations. 
  • SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. 
  • STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo. 
  • Saccharomyces cerevisiae virulence phenotype as determined with CD-1 mice is associated with the ability to grow at 42 degrees C and form pseudohyphae. 
  • Scope and Predictive Genetic/Phenotypic Signatures of Bicarbonate (NaHCO3) Responsiveness and β-Lactam Sensitization in Methicillin-Resistant Staphylococcus aureus. 
  • Screening for pain phenotypes: analysis of three congenic mouse strains on a battery of nine nociceptive assays. 
  • Screening of 16 common therapeutic drugs. Possible association with the Ah locus. 
  • Screening of 181 Patients With Antibody Deficiency for Deficiency of Adenosine Deaminase 2 Sheds New Light on the Disease in Adulthood. 
  • Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma: genotype-phenotype correlation. 
  • Secondary analysis of case-control association studies: Insights on weighting-based inference motivate a new specification test. 
  • Seed after-ripening and dormancy determine adult life history independently of germination timing. 
  • Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. 
  • Segregation analysis in cutaneous malignant melanoma/dysplastic nevus syndrome families. 
  • Segregation of recombinant chromatids following mitotic crossing over in yeast. 
  • Seizure disorders in mutant mice: relevance to human epilepsies. 
  • Selecting cases for whom additional tests can improve prognostication. 
  • Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae. 
  • Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. 
  • Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs. 
  • Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. 
  • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. 
  • Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans. 
  • Sensitivity of whole exome sequencing in detecting infantile- and late-onset Pompe disease. 
  • Sensory and Psychological Factors Predict Exercise-Induced Shoulder Injury Responses in a High-Risk Phenotype Cohort. 
  • Sequence requirements for Rev multimerization in vivo. 
  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. 
  • Sequential delivery of maturation stimuli increases human dendritic cell IL-12 production and enhances tumor antigen-specific immunogenicity. 
  • Serological and biochemical characterization of monoclonal antibodies against red cell markers related to expression of Lutheran blood group antigens. 
  • Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. 
  • Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. 
  • Serum biomarkers associated with baseline clinical severity in young steroid-naïve Duchenne muscular dystrophy boys. 
  • Serum lipids in the GENECARD study of coronary artery disease identify quantitative trait loci and phenotypic subsets on chromosomes 3q and 5q. 
  • Severe combined immunodeficiency (SCID) with natural killer (NK) cell predominance. 
  • Severe combined immunodeficiency with natural killer-cell predominance: abrogation of graft-versus-host disease and immunologic reconstitution with HLA-identical bone marrow cells. 
  • Severe disease presentation and poor outcomes among pediatric systemic lupus erythematosus patients in South Africa. 
  • Severe multisystem pathology, metabolic acidosis, mitochondrial dysfunction, and early death associated with an X-linked AIFM1 variant. 
  • Sex determination: An avian sexual revolution. 
  • Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders. 
  • Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. 
  • Sex-specific homeodomain proteins Sxi1alpha and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans. 
  • Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis. 
  • Shared heritability and functional enrichment across six solid cancers. 
  • Sib-pair linkage analysis in late onset Alzheimer's disease. 
  • Sibling phenotype concordance in classical infantile Pompe disease. 
  • Similarities and differences in early retinal phenotypes in hypertension and diabetes. 
  • Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV. 
  • Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials. 
  • Single-headed myosin II acts as a dominant negative mutation in Dictyostelium. 
  • Six subphenotypes in septic shock: Latent class analysis of the PROWESS Shock study. 
  • Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice. 
  • Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet. 
  • Skin deep: The decoupling of genetic admixture levels from phenotypes that differed between source populations. 
  • Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. 
  • Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities. 
  • Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. 
  • Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenotype. 
  • Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. 
  • Social, behavioral, and genetic linkages from adolescence into adulthood. 
  • Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. 
  • Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis. 
  • Somatic Mutations in Vascular Malformations of Hereditary Hemorrhagic Telangiectasia Result in Bi-allelic Loss of ENG or ACVRL1. 
  • Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation. 
  • Sox2 is required for development of taste bud sensory cells. 
  • SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis. 
  • Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid. 
  • Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. 
  • Species' traits do not converge on optimum values in preferred habitats. 
  • Specific podocin mutations correlate with age of onset in steroid-resistant nephrotic syndrome. 
  • Ssk2 mitogen-activated protein kinase kinase kinase governs divergent patterns of the stress-activated Hog1 signaling pathway in Cryptococcus neoformans. 
  • Stability of plant immune-receptor resistance proteins is controlled by SKP1-CULLIN1-F-box (SCF)-mediated protein degradation. 
  • Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal. 
  • Stac3 is a component of the excitation-contraction coupling machinery and mutated in Native American myopathy. 
  • Stall encodes an ADAMTS metalloprotease and interacts genetically with Delta in Drosophila ovarian follicle formation. 
  • Stathmin-deficient mice develop an age-dependent axonopathy of the central and peripheral nervous systems. 
  • Statistical considerations for analysis of microarray experiments. 
  • Statistical genetics of an annual plant, Impatiens capensis. I. Genetic basis of quantitative variation. 
  • Statistical genetics of an annual plant, Impatiens capensis. II. Natural selection. 
  • Stereoselective bupropion hydroxylation as an in vivo phenotypic probe for cytochrome P4502B6 (CYP2B6) activity. 
  • Steroidogenic factor 1 is the essential transcript of the mouse Ftz-F1 gene. 
  • Strain-specific spontaneous and NNK-mediated tumorigenesis in Pten+/- mice. 
  • Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. 
  • Strategy for investigating interactions between measured genes and measured environments. 
  • Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones. 
  • Structure of the Z Ring-associated Protein, ZapD, Bound to the C-terminal Domain of the Tubulin-like Protein, FtsZ, Suggests Mechanism of Z Ring Stabilization through FtsZ Cross-linking. 
  • Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals. 
  • Subacute limb ischemia induces skeletal muscle injury in genetically susceptible mice independent of vascular density. 
  • Subtelomeric deletions of chromosome 6p: molecular and cytogenetic characterization of three new cases with phenotypic overlap with Ritscher-Schinzel (3C) syndrome. 
  • Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer. 
  • Suppression of trkB expression by antisense oligonucleotides alters a neuronal phenotype in the rod pathway of the developing rat retina. 
  • Surface loop dynamics in adeno-associated virus capsid assembly. 
  • Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8. 
  • Symptom-based patient stratification in mental illness using clinical notes. 
  • Synergism and Antagonism of Proximate Mechanisms Enable and Constrain the Response to Simultaneous Selection on Body Size and Development Time: An Empirical Test Using Experimental Evolution. 
  • Synergistic derepression of gibberellin signaling by removing RGA and GAI function in Arabidopsis thaliana. 
  • Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. 
  • Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine? 
  • Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii. 
  • Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells. 
  • Systems Biology of Phenotypic Robustness and Plasticity. 
  • Systems biology of robustness and homeostatic mechanisms. 
  • T cell-inflamed phenotype and increased Foxp3 expression in infiltrating T-cells of mismatch-repair deficient endometrial cancers. 
  • T cells and T-cell subsets in a large population of patients with primary immunodeficiency. 
  • T helper 2-dominant antilymphoma immune response is associated with fatal outcome. 
  • T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1. 
  • TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • TGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis. 
  • TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial. 
  • TSPEAR variants are primarily associated with ectodermal dysplasia and tooth agenesis but not hearing loss: A novel cohort study. 
  • Taking a developmental perspective on systems biology. 
  • Taking cardiovascular genetic association studies to the next level. 
  • Tamoxifen pharmacogenomics: the role of CYP2D6 as a predictor of drug response. 
  • Target recognition by the archenteron during sea urchin gastrulation. 
  • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. 
  • Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. 
  • Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult. 
  • Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment. 
  • Targeting RNA in mammalian systems with small molecules. 
  • Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer. 
  • Tat-functionalized near-infrared emissive polymersomes for dendritic cell labeling. 
  • Tau is essential to beta -amyloid-induced neurotoxicity. 
  • Telomerase, cell immortality, and cancer. 
  • Tenascin-C knockout mouse has no detectable tenascin-C protein. 
  • Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls. 
  • Testing gene-treatment interactions in pharmacogenetic studies. 
  • Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. 
  • The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen. 
  • The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells. 
  • The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects. 
  • The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia. 
  • The Adolescent Cardio-Renal Intervention Trial (AdDIT): retinal vascular geometry and renal function in adolescents with type 1 diabetes. 
  • The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data. 
  • The BMP antagonists Chordin and Noggin have essential but redundant roles in mouse mandibular outgrowth. 
  • The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder. 
  • The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans. 
  • The CINRG Becker Natural History Study: Baseline characteristics. 
  • The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. 
  • The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis. 
  • The Chado Natural Diversity module: a new generic database schema for large-scale phenotyping and genotyping data. 
  • The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer. 
  • The Cryptococcus neoformans catalase gene family and its role in antioxidant defense. 
  • The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. 
  • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. 
  • The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors. 
  • The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment. 
  • The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery. 
  • The Fawn-Hooded (FH/Wjd) rat: a genetic animal model of comorbid depression and alcoholism. 
  • The French-American-British (FAB) classification of leukemia. The Pediatric Oncology Group experience with lymphocytic leukemia. 
  • The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. 
  • The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia. 
  • The Human Phenotype Ontology: Semantic Unification of Common and Rare Disease. 
  • The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting. 
  • The Impact of Environmental Factors on Monogenic Mendelian Diseases. 
  • The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. 
  • The Polygenic and Monogenic Basis of Blood Traits and Diseases. 
  • The Reproducibility of Racial Differences in Ambulatory Blood Pressure Phenotypes and Measurements. 
  • The Respiratory Phenotype of Pompe Disease Mouse Models. 
  • The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. 
  • The Singapore flagship programme in translational and clinical research in psychosis. 
  • The Systemic Juvenile Idiopathic Arthritis Cohort of the Childhood Arthritis and Rheumatology Research Alliance Registry: 2010-2013. 
  • The Trait Repertoire Enabling Cyanobacteria to Bloom Assessed through Comparative Genomic Complexity and Metatranscriptomics. 
  • The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. 
  • The adaptive radiation of lichen-forming Teloschistaceae is associated with sunscreening pigments and a bark-to-rock substrate shift. 
  • The alternative oxidase of plant mitochondria is involved in the acclimation of shoot growth at low temperature. A study of Arabidopsis AOX1a transgenic plants. 
  • The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism. 
  • The biology of malignant gliomas--a comprehensive survey. 
  • The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis. 
  • The broader autism phenotype in simplex and multiplex families. 
  • The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. 
  • The case for strategic international alliances to harness nutritional genomics for public and personal health. 
  • The chromosomal region containing pab-1, mip, and the A mating type locus of the secondarily homothallic homobasidiomycete Coprinus bilanatus. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The coenrichment of stem cells, prothymocytes, and stromal elements with ecotropic retrovirus-producing cells from the bone marrow of leukemia-prone AKR mice. 
  • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. 
  • The complex genetics of gait speed: genome-wide meta-analysis approach. 
  • The current clinical value of the DCIS Score. 
  • The development and evolution of exaggerated morphologies in insects. 
  • The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center. 
  • The distinct roles of insulin signaling in polyphenic development. 
  • The dopamine D4 receptor and the hyperactivity phenotype: a developmental-epidemiological study. 
  • The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. 
  • The ecological consequences of environmentally induced phenotypic changes. 
  • The effect of CYP2C19 gene polymorphisms on the pharmacokinetics and pharmacodynamics of prasugrel 5-mg, prasugrel 10-mg and clopidogrel 75-mg in patients with coronary artery disease. 
  • The effect of alpha-v integrin inhibition on the malignant characteristics of medulloblastoma. 
  • The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients. 
  • The effect of enzymatically degradable poly (ethylene glycol) hydrogels on smooth muscle cell phenotype 
  • The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes. 
  • The emerging phenotype of late-onset Pompe disease: A systematic literature review. 
  • The emerging phenotype of long-term survivors with infantile Pompe disease. 
  • The essential sequence elements required for RNAP II carboxyl-terminal domain function in yeast and their evolutionary conservation. 
  • The evolution of quantitative traits in complex environments 
  • The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus. 
  • The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. 
  • The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila. 
  • The future of cardiovascular clinical research: informatics, clinical investigators, and community engagement. 
  • The gene expression profiles of medulloblastoma cell lines resistant to preactivated cyclophosphamide. 
  • The genetic and environmental contributions to oppositional defiant behavior: a multi-informant twin study. 
  • The genetic architecture and evolution of life-history divergence among perennials in the Mimulus guttatus species complex. 
  • The genetic basis of a flower-color polymorphism in the common 
  • The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. 
  • The genetics of dementia in late life. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. 
  • The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo. 
  • The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. 
  • The human myoepithelial cell displays a multifaceted anti-angiogenic phenotype. 
  • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. 
  • The impact of HIV-1 infection on phenotypic and functional parameters of cellular immunity in chimpanzees. 
  • The importance of managing the patient and not the gene: expanded phenotype of GLE1-associated arthrogryposis. 
  • The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors. 
  • The influence of drug properties and host factors on delayed onset of symptoms in drug-induced liver injury. 
  • The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart. 
  • The many substrates and functions of ATM. 
  • The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis. 
  • The molecular basis of disease variability among cystic fibrosis patients carrying the 3849+10 kb C-->T mutation. 
  • The more things change, the more they stay the same? When is trait variability important for stability of ecosystem function in a changing environment. 
  • The myth of genetic enhancement. 
  • The naturalist in a world of genomics. 
  • The nature of robustness in development. 
  • The near-naked hairless (Hr(N)) mutation disrupts hair formation but is not due to a mutation in the Hairless coding region. 
  • The ocular phenotype of the Bardet-Biedl syndrome. Comparison to non-syndromic retinitis pigmentosa. 
  • The oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes. 
  • The pharmacogenetics of antiplatelet agents: towards personalized therapy? 
  • The phenotype of bilateral hippocampal sclerosis and its management in "real life" clinical settings. 
  • The phenotype of human placental macrophages and its variation with gestational age. 
  • The phenotypic and genetic signatures of common musculoskeletal pain conditions. 
  • The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis. 
  • The primary antibody repertoire: the somatic genotype and paratopic phenotype of B-cell populations. 
  • The pulling, pushing and fusing of lens fibers: a role for Rho GTPases. 
  • The quick and the dead: microbial demography at the yeast thermal limit. 
  • The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. 
  • The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy. 
  • The relationship between restrictive and repetitive behaviors in individuals with autism and obsessive compulsive symptoms in parents. 
  • The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease. 
  • The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors. 
  • The role of HOM-C genes in segmental transformations: reexamination of the Drosophila Sex combs reduced embryonic phenotype. 
  • The role of Osteopontin in tumor metastasis. 
  • The role of Sfrp and DKK proteins in cardiomyocyte development. 
  • The role of developmental plasticity in evolutionary innovation. 
  • The role of diversification in community assembly of the oaks (Quercus L.) across the continental U.S. 
  • The secreted metalloprotease ADAMTS20 is required for melanoblast survival. 
  • The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death. 
  • The shared genetic architecture between epidemiological and behavioral traits with lung cancer. 
  • The study of nevi in British twins: study design and description of the data set. 
  • The surface envelope protein gene region of equine infectious anemia virus is not an important determinant of tropism in vitro. 
  • The tRNA-Tyr gene family of Saccharomyces cerevisiae: agents of phenotypic variation and position effects on mutation frequency. 
  • The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth. 
  • The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities. 
  • The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells. 
  • The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. 
  • The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish. 
  • The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient. 
  • Thirteen novel NPHS1 mutations in a large cohort of children with congenital nephrotic syndrome. 
  • This paper is the winner of an SFB Award in the Hospital Intern, Residency category: Peptide biomaterials raising adaptive immune responses in wound healing contexts. 
  • Three new adenosine deaminase mutations that define a splicing enhancer and cause severe and partial phenotypes: implications for evolution of a CpG hotspot and expression of a transduced ADA cDNA. 
  • Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis. 
  • Threonine biosynthetic genes are essential in Cryptococcus neoformans. 
  • Thromboxane augmentation of alloreactive T cell function. 
  • Thymic epithelial defects and predisposition to autoimmune disease in BB rats. 
  • Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. 
  • Thymoma: lymphoid and epithelial components mirror the phenotype of normal thymus. 
  • Timing of plant immune responses by a central circadian regulator. 
  • Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. 
  • Tissue-specific inactivation of murine M6P/IGF2R. 
  • Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators. 
  • Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. 
  • Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds. 
  • Toward Synthesizing Our Knowledge of Morphology: Using Ontologies and Machine Reasoning to Extract Presence/Absence Evolutionary Phenotypes across Studies. 
  • Toward an animal model for antisocial behavior: parallels between mice and humans. 
  • Toward understanding cancer stem cell heterogeneity in the tumor microenvironment. 
  • Townes-Brocks syndrome: twenty novel SALL1 mutations in sporadic and familial cases and refinement of the SALL1 hot spot region. 
  • Trait-based variation in host contribution to pathogen transmission across species and resource supplies. 
  • Trait-to-gene: a computational method for predicting the function of uncharacterized genes. 
  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. 
  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. 
  • Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation. 
  • Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. 
  • Transcriptional profile of the Arabidopsis root quiescent center. 
  • Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. 
  • Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations. 
  • Transcriptomic biomarkers for the accurate diagnosis of myocarditis. 
  • Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy. 
  • Transformation of cell type in uveal melanomas: a quantitative histologic analysis. 
  • Transgenic plants expressing potato virus X ORF2 protein (p24) are resistant to tobacco mosaic virus and Ob tobamoviruses. 
  • Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma. 
  • Transmission of Hypervirulence traits via sexual reproduction within and between lineages of the human fungal pathogen cryptococcus gattii. 
  • Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences. 
  • Treating the enigmatic "exceptional responders" as patients with undiagnosed diseases. 
  • Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry. 
  • Treatment outcome of creatine transporter deficiency: international retrospective cohort study. 
  • Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3. 
  • Trio-based exome sequencing arrests de novo mutations in early-onset high myopia. 
  • Triple-hit B-cell Lymphoma With MYC, BCL2, and BCL6 Translocations/Rearrangements: Clinicopathologic Features of 11 Cases. 
  • Troponin T3 expression in skeletal and smooth muscle is required for growth and postnatal survival: characterization of Tnnt3(tm2a(KOMP)Wtsi) mice. 
  • True paternal care in a multi-male primate society. 
  • Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients. 
  • Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity. 
  • Turner phenotype in mother and daughter. 
  • Twin studies of psychopathology: why do the concordance rates vary? 
  • Twins eye study in Tasmania (TEST): rationale and methodology to recruit and examine twins. 
  • Two Approaches to Classifying and Quantifying Physical Resilience in Longitudinal Data. 
  • Two Sides of the Same Coin: Pediatric-Onset and Adult-Onset Common Variable Immune Deficiency. 
  • Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans. 
  • Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. 
  • Two genetic changes in cis-regulatory elements caused evolution of petal spot position in Clarkia. 
  • Two mutational hotspots in the interleukin-2 receptor gamma chain gene causing human X-linked severe combined immunodeficiency. 
  • Two new loci, PLEIADE and HYADE, implicate organ-specific regulation of cytokinesis in Arabidopsis. 
  • Two novel TP63 mutations associated with the ankyloblepharon, ectodermal defects, and cleft lip and palate syndrome: a skin fragility phenotype. 
  • Type I glycogen storage diseases: disorders of the glucose-6-phosphatase complex. 
  • Type II collagen gene variants and inherited osteonecrosis of the femoral head. 
  • UBC-Nepal expedition: phenotypical evidence for evolutionary adaptation in the control of cerebral blood flow and oxygen delivery at high altitude. 
  • Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas. 
  • Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference. 
  • Understanding Evolutionary Impacts of Seasonality: An Introduction to the Symposium. 
  • Understanding Mucor circinelloides pathogenesis by comparative genomics and phenotypical studies. 
  • Understanding rice adaptation to varying agro-ecosystems: trait interactions and quantitative trait loci. 
  • Understanding the phenotypic structure of adult retrospective ADHD symptoms during childhood in the United States. 
  • Understanding the tumor microenvironment and radioresistance by combining functional imaging with global gene expression. 
  • Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of flowering time in Boechera stricta. 
  • Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. 
  • Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans. 
  • Unmasking a role for sex chromosomes in gene silencing. 
  • Unmodern Synthesis: Developmental Hierarchies and the Origin of Phenotypes. 
  • Unreported Missense Mutation in the Dimerization Domain of ADA2 Leads to ADA2 Deficiency Associated with Severe Oral Ulcers and Neutropenia in a Female Somalian Patient-Addendum to the Genotype-Phenotype Puzzle. 
  • Urinary Anomalies in 22q11.2 Deletion (DiGeorge syndrome): From Copy Number Variations to Single-Gene Determinants of Phenotype. 
  • Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers. 
  • Use of dominant-negative HrpA mutants to dissect Hrp pilus assembly and type III secretion in Pseudomonas syringae pv. tomato. 
  • Use of enantiomeric bupropion and hydroxybupropion to assess CYP2B6 activity in glomerular kidney diseases. 
  • Use of laser scanning cytometry to study tumor microenvironment. 
  • Using Mass Spectrometry to Quantify Rituximab and Perform Individualized Immunoglobulin Phenotyping in ANCA-Associated Vasculitis. 
  • Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. 
  • Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome. 
  • Using the phenoscape knowledgebase to relate genetic perturbations to phenotypic evolution. 
  • Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis. 
  • VAP-RELATED SUPPRESSORS OF TOO MANY MOUTHS (VST) family proteins are regulators of root system architecture. 
  • VCL-ALK renal cell carcinoma in children with sickle-cell trait: the eighth sickle-cell nephropathy? 
  • Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. 
  • Vaccination with T cell-defined antigens. 
  • Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice. 
  • Validation and Refinement of Chronic Lung Allograft Dysfunction Phenotypes in Bilateral and Single Lung Recipients. 
  • Validation of association of the apolipoprotein E ε2 allele with neurodevelopmental dysfunction after cardiac surgery in neonates and infants. 
  • Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization. 
  • Variable HLA expression on deceased donor lymphocytes: Not all crossmatches are created equal. 
  • Variable phenotypic expression of mutations in genes of the immune system. 
  • Variant-specific inflation factors for assessing population stratification at the phenotypic variance level. 
  • Variation aids virulent invaders. 
  • Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. 
  • Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. 
  • Variegated aneuploidy in two siblings: phenotype, genotype, CENP-E analysis, and literature review. 
  • Vascularized composite allotransplantation: a closer look at the banff working classification. 
  • Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency. 
  • Ventricular arrhythmia in the X-linked cardiomyopathy Barth syndrome. 
  • Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches. 
  • Viruses and microRNAs: RISCy interactions with serious consequences. 
  • Vision of correction for classic homocystinuria. 
  • Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. 
  • Vmat2 heterozygous mutant mice display a depressive-like phenotype. 
  • Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. 
  • WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4. 
  • Waiting for two mutations: with applications to regulatory sequence evolution and the limits of Darwinian evolution. 
  • Warts and DADA2: a Mere Coincidence? 
  • What Clues Can We Use From Primary Sclerosing Cholangitis With Inflammatory Bowel Disease Phenotypes? 
  • What General and Pain-associated Psychological Distress Phenotypes Exist Among Patients with Hip and Knee Osteoarthritis? 
  • What can knockout mice contribute to an understanding of hypertension? 
  • What can patterns of differentiation across plant genomes tell us about adaptation and speciation? 
  • What causes hidradenitis suppurativa ?-15 years after. 
  • What's New in Genetic Testing for Cancer Susceptibility? 
  • When sensing is gambling: An experimental system reveals how plasticity can generate tunable bet-hedging strategies. 
  • Which evolutionary processes influence natural genetic variation for phenotypic traits? 
  • Whole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism. 
  • Whole blood gene expression testing for coronary artery disease in nondiabetic patients: major adverse cardiovascular events and interventions in the PREDICT trial. 
  • Whole blood sequencing reveals circulating microRNA associations with high-risk traits in non-ST-segment elevation acute coronary syndrome. 
  • Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. 
  • Whole genome sequencing reveals novel IGHMBP2 variant leading to unique cryptic splice-site and Charcot-Marie-Tooth phenotype with early onset symptoms. 
  • Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios. 
  • Whole-exome sequencing of a pedigree segregating asthma. 
  • Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program. 
  • Whole-genome sequencing of Staphylococcus epidermidis bloodstream isolates from a prospective clinical trial reveals that complicated bacteraemia is caused by a limited number of closely related sequence types. 
  • Why species tell more about traits than traits about species: predictive analysis. 
  • Wild female baboons bias their social behaviour towards paternal half-sisters. 
  • Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis. 
  • Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. 
  • Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment. 
  • Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. 
  • Yeast base excision repair: interconnections and networks. 
  • ZPLD1 gene is disrupted in a patient with balanced translocation that exhibits cerebral cavernous malformations. 
  • Zidovudine resistance, syncytium-inducing phenotype, and HIV disease progression in a case-control study. The VA Cooperative Study Group. 
  • crinkled reveals a new role for Wingless signaling in Drosophila denticle formation. 
  • dictyBase--a Dictyostelium bioinformatics resource update. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
  • myotilin Mutation found in second pedigree with LGMD1A. 
  • optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry 
  • speck, First Identified in Drosophila melanogaster in 1910, Is Encoded by the Arylalkalamine N-Acetyltransferase (AANAT1) Gene. 
  • β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model. 
• 

  Keywords of People

  • Abbruzzese, James, D. C. I. Distinguished Professor of Medical Oncology, Medicine, Medical Oncology
  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Allori, Alexander C, Associate Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery
  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
  • Case, Laura Elizabeth, Associate Professor in Orthopaedic Surgery, Pediatrics, Medical Genetics
  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology
  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor for Research in Molecular Biology, Cell Biology
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • Jowell, Paul Simon, Professor of Medicine, Medicine, Gastroenterology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology
  • Li, Yi-Ju, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Murdoch, David Martin, Associate Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Roth, V. Louise, Professor of Biology, Evolutionary Anthropology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Starmer, Charles Franklin, Professor Emeritus of Computer Science, Computer Science
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Immunology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Adjunct Professor of Pathology, Pathology