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Subject Areas on Research
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"Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes?
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1,2-Diacylglycerol choline phosphotransferase catalyzes the final step in the unique Treponema denticola phosphatidylcholine biosynthesis pathway.
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A calorimetric and monolayer investigation of the influence of ions on the thermodynamic properties of phosphatidylcholine.
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A new helper phospholipid for gene delivery.
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A new monofluorinated phosphatidylcholine forms interdigitated bilayers.
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A novel micropipet method for measuring the bending modulus of vesicle membranes.
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A nuclear magnetic resonance study of the interaction of L-epinephrine with phospholipid vesicles.
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A synthetic lecithin containing branched-chain fatty acids: physical properties and membrane studies.
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A thermodynamic study of the partition of n-hexane into phosphatidylcholine and phosphatidylcholine-cholesterol bilayers.
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Abnormal lipid composition of the red cell membrane in congenital dyserythropoietic anemia type II (HEMPAS).
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Alterations of new methylated phospholipid synthesis in the plasma membranes of macrophages exposed to chemoattractants.
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Amiodarone-liposome interaction: a multinuclear NMR and X-ray diffraction study.
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Amphotericin B lipid complex for invasive fungal infections: analysis of safety and efficacy in 556 cases.
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An electron spin resonance study of cholestane spin label in aqueous mixtures of biliary lipids.
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Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.
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Application of the temperature-jump technique to the study of phospholipid dispersions.
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Benzodiazepine and beta-adrenergic receptor ligands independently stimulate phospholipid methylation.
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Biliary secretion of extracorporeal porcine livers with single and dual vessel perfusion.
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Bombesin increases fetal lung growth and maturation in utero and in organ culture.
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Bombesin-like peptide and receptors in lung injury models: diverse gene expression, similar function.
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CD10/neutral endopeptidase 24.11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin-like peptides.
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Calcium binding by monosulfate esters of taurochenodeoxycholate.
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Can regular solution theory be applied to lipid bilayer membranes?
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Cellular uptake and processing of surfactant lipids and apoprotein SP-A by rat lung.
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Changes in lipid profiles of liver microsomes of rats following intratracheal administration of DDT or endosulfan.
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Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia.
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Cholesterol modifies the short-range repulsive interactions between phosphatidylcholine membranes.
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Chromogenic assay for phospholipase C from Bacillus cereus.
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Comparative incorporation of P32 into lung phosphatidyl choline in mammals with different metabolic and pulmonary morphologic characteristics.
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Comparative safety of amphotericin B lipid complex and amphotericin B deoxycholate as aerosolized antifungal prophylaxis in lung-transplant recipients.
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Contributions of hydration and steric (entropic) pressures to the interactions between phosphatidylcholine bilayers: experiments with the subgel phase.
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Cooperative activation of human factor IX by the human extrinsic pathway of blood coagulation.
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Correlated x-ray diffraction and freeze-fracture studies on membrane model systems. Perturbations induced by freeze-fracture preparative procedures.
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Cytosolic delivery of macromolecules 4. Head group-dependent membrane permeabilization by pH-sensitive detergents.
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Cytosolic phospholipase A(2) activity associated with nuclei is not inhibited by arachidonyl trifluoromethyl ketone in macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin.
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DIACYLGLYCEROL ACYLTRANSFERASE1 Contributes to Freezing Tolerance.
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Determination of the depth of bromine atoms in bilayers formed from bromolipid probes.
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Direct electrochemistry of hemoglobin in egg-phosphatidylcholine films and its catalysis to H(2)O(2).
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Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential.
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Effect of chain length and unsaturation on elasticity of lipid bilayers.
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Effect of gamma irradiation and cystamine on kidney lipids of rats.
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Effect of protein kinase C inhibitors and activators on corneal re-epithelialization in the rat.
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Effect of retinol and retinoic acid on liver lipids of rats fed different levels of protein.
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Effect of retinol on the molecular species of hepatic phosphatidyl choline in young rats.
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Effect of whole body gamma irradiation on fatty acid composition of liver lipids of female rats and radioprotection by cystamine.
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Effects of phenylamide herbicides on the physical properties of phosphatidylcholine membranes.
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Effects of vitamin A and phenobarbital on liver endoplasmic reticulum of rats.
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Efficacy of provitamin A carotenoids in reversing vitamin A deficiency induced lesions in brain lipids of chicks.
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Electro-mechanical permeabilization of lipid vesicles. Role of membrane tension and compressibility.
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Electrostatic control of phospholipid polymorphism.
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Elevation of rat pulmonary, hepatic and lung surfactant lipids by fly ash inhalation.
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Evaluation of biosynthetic pathways of phosphatidyl choline in liver of rats given phenobarbital: a study on molecular species of phosphatidyl choline.
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Evaluation of phospholipase C and D activity in stimulated human neutrophils using a phosphono analog of choline phosphoglyceride.
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Evaluation of synthetic phospholipid ultrasound contrast agents.
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Exchange of monooleoylphosphatidylcholine as monomer and micelle with membranes containing poly(ethylene glycol)-lipid.
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Expression and site-directed mutagenesis of the phosphatidylcholine-preferring phospholipase C of Bacillus cereus: probing the role of the active site Glu146.
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Extrinsic pathway proteolytic activity.
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Failure of long term high-dose lecithin to retard progression of early-onset Alzheimer's disease.
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Fat digestion in patients with bile acid malabsorption but minimal steatorrhea.
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Hepatic microsomal phospholipids in rats exposed intratracheally to coal fly ash.
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Hepatic phosphatidylcholine synthesis in deficiency of lysine and threonine: effect of malathion.
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Hydration and steric pressures between phospholipid bilayers.
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Hydration force and bilayer deformation: a reevaluation.
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Hydration properties of lamellar and non-lamellar phases of phosphatidylcholine and phosphatidylethanolamine.
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Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
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Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI).
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Impaired plasmalogens in patients with schizophrenia.
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In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury.
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In vivo acylation of triglycerides and phosphoglycerides of liver subcellular fractions with palmitate-1-14C in rats fed vitamin A.
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Incorporation of palmitate-1-14C into liver lipids of rats fed millet (Sorghum vulgarie) at different protein levels.
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Increase in oxidative stress as measured by cerebrospinal fluid lipid peroxidation during treatment for childhood acute lymphoblastic leukemia.
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Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid.
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Induction of cytochrome P-450 and phosphatidylcholine synthesis by endosulfan in liver of rats: effect of quality of dietary proteins.
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Induction of phosphatidylcholine biosynthesis via CDPcholine pathway in lung and liver of rats following intratracheal administration of DDT and endosulfan.
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Influence of cytoskeletal assembly on phosphatidylcholine synthesis in intact phagocytic cells.
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Influence of lipid composition on physical properties and peg-mediated fusion of curved and uncurved model membrane vesicles: "nature's own" fusogenic lipid bilayer.
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Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.
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Interaction of K7Fe3+P2W17O62H2 with supported bilayer lipid membranes on platinum electrode.
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Interaction of benzene with bilayers. Thermal and structural studies.
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Interaction of halothane with lipid bilayers.
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Interaction of the antifolate antibiotic trimethoprim with phosphatidylcholine membranes: a 13C and 31P nuclear magnetic resonance study.
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Interbilayer interactions between sphingomyelin and sphingomyelin/cholesterol bilayers.
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Interdigitated hydrocarbon chain packing causes the biphasic transition behavior in lipid/alcohol suspensions.
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Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism.
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Ion channel behavior of amphotericin B in sterol-free and cholesterol- or ergosterol-containing supported phosphatidylcholine bilayer model membranes investigated by electrochemistry and spectroscopy.
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Isolated perfused lung--substrate utilization.
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Lateral diffusion in planar lipid bilayers.
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Ligatin: a peripheral membrane protein with covalently bound palmitic acid.
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Lipid bilayer and water proton magnetization transfer: effect of cholesterol.
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Lipid specificity of beta-hydroxybutyrate dehydrogenase activation.
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Lipidomics identifies a requirement for peroxisomal function during influenza virus replication.
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Locally synthesized phosphatidylcholine, but not protein, undergoes rapid retrograde axonal transport in the rat sciatic nerve.
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Long- and short-range interactions between phospholipid/ganglioside GM1 bilayers.
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Loosely packed self-assembled monolayer of N-hexadecyl-3,6-di(p-mercaptophenylacetylene)carbazole on gold and its application in biomimetic membrane research.
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Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition.
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Magnitude of the solvation pressure depends on dipole potential.
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Measurement of interbilayer adhesion energies.
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Mechanisms of accumulation of arachidonic acid in cultured myocardial cells during ATP depletion.
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Mechanisms of beta-adrenergic receptor desensitization and resensitization.
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Membrane fusion promoters and inhibitors have contrasting effects on lipid bilayer structure and undulations.
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Membrane-protein structural mapping of chloroplast coupling factor in asolectin vesicles.
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Metabolic network failures in Alzheimer's disease: A biochemical road map.
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Metabolism of subfractions of phosphatidyl choline & phosphatidyl ethanolamine of liver & plasma of rats given retinol & phenobarbital.
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Microemulsions of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein.
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Modulation of poly(ethylene glycol)-induced fusion by membrane hydration: importance of interbilayer separation.
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Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface.
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Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon/water interface.
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Molecular and cellular processing of lung surfactant.
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Molecular species of phosphatidyl choline and phosphatidyl ethanolamine in heart of rats given excess vitamin A.
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Morphology of the intermediate stages in the lamellar to hexagonal lipid phase transition.
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Mortality rates in comparative trials of formulations of amphotericin B.
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New structural model for mixed-chain phosphatidylcholine bilayers.
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Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation.
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O-Alkyl dioleoylphosphatidylcholinium compounds: the effect of varying alkyl chain length on their physical properties and in vitro DNA transfection activity.
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On the localization of ubiquinone in phosphatidylcholine bilayers.
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One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
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Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data.
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Oxidative changes in cerebral spinal fluid phosphatidylcholine during treatment for acute lymphoblastic leukemia.
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Oxidative stress and neurobehavioral problems in pediatric acute lymphoblastic leukemia patients undergoing chemotherapy.
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Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice.
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Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.
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Pathogenesis of hepatic steatosis in the parenterally fed rat.
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Perinatal dietary supplementation with a commercial soy lecithin preparation: effects on behavior and brain biochemistry in the developing rat.
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Perinatal dietary supplementation with a soy lecithin preparation: effects on development of central catecholaminergic neurotransmitter systems.
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Phase-lifetime spectrophotometry of deoxycholate-purified bacteriorhodopsin reconstituted into asolectin vesicles.
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Phosphatidylcholine Biosynthesis in Mitis Group Streptococci via Host Metabolite Scavenging.
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Phosphatidylcholine composition of pulmonary surfactant from terrestrial and marine diving mammals.
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Phosphatidylcholine metabolism in lung microsomes and lung surfactant of rats exposed intratracheally to coal fly ash.
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Phosphatidylcholine transfer protein promotes apolipoprotein A-I-mediated lipid efflux in Chinese hamster ovary cells.
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Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes.
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Phospholipid-protein adducts of lipid peroxidation: synthesis and study of new biotinylated phosphatidylcholines.
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Physical and biological properties of cationic triesters of phosphatidylcholine.
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Plasma 1-palmitoyl-2-linoleoyl phosphatidylcholine. Evidence for extensive phospholipase A1 hydrolysis and hepatic metabolism of the products.
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Plasticity of lipid-protein interactions in the function and topogenesis of the membrane protein lactose permease from Escherichia coli.
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Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.
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Polyphenols increase adhesion between lipid bilayers by forming interbilayer bridges.
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Porcine hepatic phospholipid efflux during reperfusion after cold ischemia.
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Potential role of aerosolized amphotericin B formulations in the prevention and adjunctive treatment of invasive fungal infections.
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Preparation and characterization of unilamellar vesicles from cholate-phospholipid micelle treated with cholestyramine.
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Probing the ethanol-induced chain interdigitations in gel-state bilayers of mixed-chain phosphatidylcholines.
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Properties of multilamellar liposomes containing 99mTcO4-: effect of distearoylphosphatidylcholine to sphingomyelin ratio.
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Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts.
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Purification and characterization of a lecithin-D(-)- -hydroxybutyrate dehydrogenase complex.
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Radioprotection of liver lipids of whole-body gamma-irradiated female rats by cystamine.
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Radioprotection of whole-body gamma irradiation induced alterations in lipid metabolism of liver and plasma by AET (S-2, aminoethyl isothiuronium Br. H. Br.) and serotonin in rats.
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Range of the solvation pressure between lipid membranes: dependence on the packing density of solvent molecules.
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Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner.
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Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit.
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Regulation of beta-adrenergic receptors by phospholipid methylation.
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Regulation of phosphatidylcholine homeostasis by calcium-independent phospholipase A2.
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Retinol feeding and low and high density lipoproteins of plasma of rats.
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Ribosome-independent regulation of translocon composition and Sec61alpha conformation.
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Role of water in short-range repulsive and attractive interactions between macromolecules and bilayers.
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SERUM LIPIDS IN LEPROSY BY SILICIC ACID COLUMN CHROMATOGRAPHY.
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Safety of aerosolized amphotericin B lipid complex in lung transplant recipients.
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Separation & estimation of human serum lipids by silicic acid column chromatography.
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Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation.
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Solubility of carbon dioxide in lipid bilayer membranes and organic solvents.
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Sorting of lipids and transmembrane peptides between detergent-soluble bilayers and detergent-resistant rafts.
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Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.
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Steady-state ATP synthesis by bacteriorhodopsin and chloroplast coupling factor co-reconstituted into asolectin vesicles.
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Steric repulsion between phosphatidylcholine bilayers.
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Structure and interactive properties of highly fluorinated phospholipid bilayers.
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Structure and phase behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol).
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Structure of macromolecular aggregates. II. Construction of model membranes from phospholipids and polypeptides.
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Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts.
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Studies of the ethanol-induced interdigitated gel phase in phosphatidylcholines using the fluorophore 1,6-diphenyl-1,3,5-hexatriene.
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Study of renal safety in amphotericin B lipid complex-treated patients.
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Successful use of amphotericin B lipid complex in the treatment of cryptococcosis.
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Surface ripples cause the large fluid spaces between gel phase bilayers containing small amounts of cholesterol.
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Temperature dependence of the repulsive pressure between phosphatidylcholine bilayers.
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The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.
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The effect of cholesterol on the structure of phosphatidylcholine bilayers.
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The effect of ethanol on the phase transition temperature and the phase structure of monounsaturated phosphatidylcholines.
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The effect of phloretin on the hydration of egg phosphatidylcholine multilayers.
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The influence of follicle-stimulating hormone on testicular phospholipids.
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The interaction of polyphenols with bilayers: conditions for increasing bilayer adhesion.
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The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics.
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The noneffect of a large linear hydrocarbon, squalene, on the phosphatidylcholine packing structure.
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The organization of n-alkanes in lipid bilayers.
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The water permeability of lens aquaporin-0 depends on its lipid bilayer environment.
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Theoretical analysis of lipid transport in sciatic nerve.
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Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems.
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Transmission of a procoagulant signal from tissue factor-bearing cell to platelets.
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Treatment of non-Aspergillus moulds in immunocompromised patients, with amphotericin B lipid complex.
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Ultrasonic attenuation measurements in phospholipid dispersions.
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Upake of plasma lipids by extrahepatic tissues of vitamin A fed rats.
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Use of liposomes as carriers for radiation synovectomy.
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Use of newer antifungal therapies in clinical practice: what do the data tell us?
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VSV transmembrane domain (TMD) peptide promotes PEG-mediated fusion of liposomes in a conformationally sensitive fashion.
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Vitamin A in liposomes. Inhibition of complement binding and alteration of membrane structure.
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Water permeability and mechanical strength of polyunsaturated lipid bilayers.
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Whole and disaturated lung phosphatidylcholine in cortisol-treated, intrauterine growth-retarded and twin control lambs at different gestational ages.
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X-ray diffraction to determine the thickness of raft and nonraft bilayers.
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