Phosphatidylserines

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  Subject Areas on Research

  • A potential second messenger role for unsaturated fatty acids: activation of Ca2+-dependent protein kinase. 
  • Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease. 
  • Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines. 
  • Antiphospholipid antibodies in pediatric lupus nephritis. 
  • Apoptosis and P53 induction in human lung fibroblasts exposed to chromium (VI): effect of ascorbate and tocopherol. 
  • Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. 
  • Catecholamine stimulated myocardial adenylate cyclase: effects of phospholipase digestion and the role of membrane lipids. 
  • Characterization of an acquired inhibitor to coagulation factor V. Antibody binding to the second C-type domain of factor V inhibits the binding of factor V to phosphatidylserine and neutralizes procoagulant activity. 
  • Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest. 
  • Contributions of Asn2198, Met2199, and Phe2200 in the factor VIII C2 domain to cofactor activity, phospholipid-binding, and von Willebrand factor-binding. 
  • Cooperative activation of human factor IX by the human extrinsic pathway of blood coagulation. 
  • Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. 
  • Deencryption of cellular tissue factor is independent of its cytoplasmic domain. 
  • Deletion analysis of recombinant human factor V. Evidence for a phosphatidylserine binding site in the second C-type domain. 
  • Evolution of adverse changes in stored RBCs. 
  • Extrinsic pathway proteolytic activity. 
  • Factor VIII Arg2304 --> His binds to phosphatidylserine and is a functional cofactor in the factor X-ase complex. 
  • Fluorescence studies of benzo-[a]-pyrene in liposome membrane systems. 
  • Identification of N-acylphosphatidylserine molecules in eukaryotic cells. 
  • Ionic influences on the phase transition of dipalmitoylphosphatidylserine. 
  • Myocardial guanylate cyclase: properties of the enzyme and effects of cholinergic agonists in vitro. 
  • Phase changes induced by cyclopropane of phosphatidylserine bilayers in the presence and absence of calcium. 
  • Phorbol esters down-regulate protein kinase C in rat brain cerebral cortical slices. 
  • Phosphatidylserine inhibits and calcium promotes model membrane fusion. 
  • Protein kinase C: cellular target of the second messenger arachidonic acid? 
  • The ability to recognize phosphatidylserine on apoptotic cells is an inducible function in murine bone marrow-derived macrophages. 
  • The effect of phosphatidylserine on the inhibition of human factor Xa by the plasma proteinase inhibitors. 
  • The polar lipids of Clostridium psychrophilum, an anaerobic psychrophile. 
  • Tissue factor de-encryption: ionophore treatment induces changes in tissue factor activity by phosphatidylserine-dependent and -independent mechanisms. 
  • Topology of the yeast plasma membrane proton-translocating ATPase. 
  • Transmission of a procoagulant signal from tissue factor-bearing cell to platelets. 
  • Variability in platelet procoagulant activity in healthy volunteers.