Phosphorylase Kinase

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  Subject Areas on Research

  • An engineered liver glycogen phosphorylase with AMP allosteric activation. 
  • Benign or not benign? Deep phenotyping of liver Glycogen Storage Disease IX. 
  • Calcium control of muscle phosphorylase kinase through the combined action of calmodulin and troponin. 
  • Calmodulin as an integral subunit of phosphorylase kinase from rabbit skeletal muscle. 
  • Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase. 
  • Characterization of liver GSD IX γ2 pathophysiology in a novel Phkg2-/- mouse model. 
  • Common mutation in the PHKA2 gene with variable phenotype in patients with liver phosphorylase b kinase deficiency. 
  • Diagnosis and management of glycogen storage diseases type VI and IX: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). 
  • Genetically engineered calmodulins differentially activate target enzymes. 
  • Glycogen storage disease type IX: novel PHKA2 missense mutation and cirrhosis. 
  • Protein (serine and threonine) phosphate phosphatases. 
  • Role of autophosphorylation in regulating calmodulin-dependent protein kinases. 
  • The amino acid sequence of the delta subunit (calmodulin) of rabbit skeletal muscle phosphorylase kinase. 
  • The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle. 
  • Variability of disease spectrum in children with liver phosphorylase kinase deficiency caused by mutations in the PHKG2 gene.