Phosphorylcholine
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Subject Areas on Research
- A multicenter randomized masked comparison trial of synthetic surfactant versus calf lung surfactant extract in the prevention of neonatal respiratory distress syndrome.
- A multicenter randomized, masked comparison trial of natural versus synthetic surfactant for the treatment of respiratory distress syndrome.
- A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
- A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma.
- Aerosol characteristics of 99mTc-pentetic acid (DTPA) and synthetic surfactant (Exosurf).
- Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension.
- Artificial surfactant attenuates hyperoxic lung injury in primates. I. Physiology and biochemistry.
- Artificial surfactant attenuates hyperoxic lung injury in primates. II. Morphometric analysis.
- Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase.
- Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes.
- Genetic engineering of a single-chain antibody fragment for surface immobilization in an optical biosensor.
- Induction of phosphatidylcholine biosynthesis via CDPcholine pathway in lung and liver of rats following intratracheal administration of DDT and endosulfan.
- Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism.
- Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies.
- Nanoporous microbead supported bilayers: stability, physical characterization, and incorporation of functional transmembrane proteins.
- One-year outcome in 232 premature infants with birth weights of 750 to 1249 grams and respiratory distress syndrome randomized to rescue treatment with two doses of synthetic surfactant or air placebo. Canadian Exosurf Neonatal Study Group.
- Outcome at 1-year adjusted age of 957 infants weighing more than 1250 grams with respiratory distress syndrome randomized to receive synthetic surfactant or air placebo. American and Canadian Exosurf Neonatal Study Groups.
- Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
- Perifosine as a potential novel anti-telomerase therapy.
- Perifosine treatment in chronic lymphocytic leukemia: results of a phase II clinical trial and in vitro studies.
- Physical and biological properties of cationic triesters of phosphatidylcholine.
- Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.
- Quantitative proton spectroscopy of canine brain: in vivo and in vitro correlations.
- Reciprocal expansions of idiotypic and anti-idiotypic clones following antigen stimulation.
- Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome.
- Stimulation of phosphorylcholine turnover and diacylglycerol production in human polymorphonuclear leukocytes. Novel assay for phosphorylcholine.
- Synthesis and antifungal activities of miltefosine analogs.
- Synthesis and characterization of carbohydrate-based phospholipids.
- The structural basis of repertoire shift in an immune response to phosphocholine.
- Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1.
- Ulcerative keratitis in gastrointestinal stromal tumor patients treated with perifosine.
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Keywords of People
- Charles, Hal Cecil, Associate Professor of Radiology, Radiology