Pituitary Gland

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  Subject Areas on Research

  • 9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors. 
  • A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. 
  • Absent pituitary gland in two brothers with an oral-facial-digital syndrome resembling OFDS II and VI: a new type of OFDS? 
  • Acromegaly and Cushing's syndrome associated with a foregut carcinoid tumor. 
  • Agonist-induced desensitization of the D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland. 
  • Anatomical considerations for endoscopic endonasal skull base surgery in pediatric patients. 
  • Anogenital distance at birth as a predictor of volume of the sexually dimorphic nucleus of the preoptic area of the hypothalamus and pituitary responsiveness in castrated adult rats. 
  • Anti-estrogenic compounds increase prolactin and growth hormone synthesis in clonal strains of rat pituitary cells. 
  • Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5'-flanking sequences to the hypothalamus. 
  • Binding of [125I]-N-(p-aminophenethyl)spiroperidol to the D-2 dopamine receptor in the neurointermediate lobe of the rat pituitary gland: a thermodynamic study. 
  • Comments on "Radiotherapy for nasopharyngeal carcinoma: shielding the pituitary may improve therapeutic ratio". 
  • Delta 9-tetrahydrocannabinol suppression of prolactin secretion in the rat: lack of direct pituitary effect. 
  • Developmental biology of hepatic phenylalanine hydroxylase activity in foetal and neonatal rats synchronized as to conception. 
  • Developmental changes in pituitary-gonadal function in free-ranging lions (Panthera leo leo) of the Serengeti Plains and Ngorongoro Crater 
  • Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHalpha promoter. 
  • Dopamine receptors: from structure to function. 
  • Dose-response characteristics of neonatal exposure to genistein on pituitary responsiveness to gonadotropin releasing hormone and volume of the sexually dimorphic nucleus of the preoptic area (SDN-POA) in postpubertal castrated female rats. 
  • Effect of ether stress on growth hormone during development in the neonatal rat. 
  • Effect of neonatal diethylstilbestrol exposure on luteinizing hormone secretion following ketamine anesthesia and gonadotropin-releasing hormone in castrated postpubertal rats. 
  • Effect of neonatal diethylstilbestrol exposure on volume of the sexually dimorphic nucleus of the preoptic area of the hypothalamus and pituitary responsiveness to gonadotropin-releasing hormone in female rats of known anogenital distance at birth. 
  • Effect of vinblastine on neurohypophysial and adenohypophysial microtubules. 
  • Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley rats. 
  • Effects of charcoal-extracted follicular fluid on reproductive function in postpartum cows. 
  • Effects of megestrol acetate on pituitary function and end-organ hormone secretion: a post hoc analysis of serum samples from a 12-week study in healthy older men. 
  • Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency. 
  • Endocrine modulation of reproduction. 
  • Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells. 
  • Enhanced central response to dehydration in mice lacking angiotensin AT(1a) receptors. 
  • Expression and hormonal regulation of coactivator and corepressor genes. 
  • Expression of CDK4 or CDK2 in mouse oral cavity is retained in adult pituitary with distinct effects on tumorigenesis. 
  • Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase. 
  • Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1. 
  • Hormonal characteristics of free-ranging female lions (Panthera leo) of the Serengeti Plains and Ngorongoro Crater. 
  • Hypothalamic and pituitary function in hypogonadotropic hypogonadism. 
  • Immunohistochemical expression of retinoid X receptor isoforms in human pituitaries and pituitary adenomas. 
  • Impact and cost of care of venous thromboembolism following pituitary surgery. 
  • In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. 
  • In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: relationship to dexamethasone suppression test results in patients. 
  • Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function. 
  • Increased pituitary volume in ...psychosis study. 
  • Intra-operative MR guidance during trans-sphenoidal pituitary resection: preliminary results. 
  • Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. 
  • Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland. 
  • Isoform-specific thyroid hormone receptor antibodies detect multiple thyroid hormone receptors in rat and human pituitaries. 
  • Lack of annexin 1 results in an increase in corticotroph number in male but not female mice. 
  • Large pituitary gland with an expanding lesion in the context of neurofibromatosis 1. 
  • Localization of specific binding sites for atrial natriuretic factor in peripheral tissues of the guinea pig, rat, and human. 
  • MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences. 
  • MR imaging of physiologic pituitary gland hypertrophy in adolescence. 
  • Magnetic resonance imaging in idiopathic hypopituitarism. 
  • Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. 
  • Neuropeptides and neurotransmitters in Alzheimer's disease: focus on corticotrophin releasing factor. 
  • Ontogeny of mu- and kappa-opiate receptor control of the hypothalamo-pituitary-adrenal axis in rats. 
  • Opposing LSD1 complexes function in developmental gene activation and repression programmes. 
  • Ovarian stimulation for in vitro fertilization using pure follicle-stimulating hormone with and without gonadotropin-releasing hormone agonist in high-responder patients. 
  • Pharmacokinetics of growth hormone secretion in humans induced by growth hormone releasing hormone. 
  • Pituitary abnormalities in eating disorders: further evidence from MRI studies. 
  • Pituitary size in depression. 
  • Pituitary volumes in pediatric maltreatment-related posttraumatic stress disorder. 
  • Pituitary-thyroid axis reactivity to hyper- and hypothyroidism in the perinatal period: ontogeny of regulation of regulation and long-term programming of responses. 
  • Placental hormones and the control of maternal metabolism and fetal growth. 
  • Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse. 
  • Regulation by and of calmodulin in mammalian cells. 
  • Sorbitol dehydrogenase of rat testis: changes of activity during development, after hypophysectomy and following gonadotrophic hormone administration. 
  • Specificity of receptor-G protein interactions. Discrimination of Gi subtypes by the D2 dopamine receptor in a reconstituted system. 
  • Structure and expression of a membrane component of the inhibin receptor system. 
  • Structure and function of the ovine type 1 corticotropin releasing factor receptor (CRF1) and a carboxyl-terminal variant. 
  • Superior hypophyseal artery aneurysms have the lowest recurrence rate with endovascular therapy. 
  • Suppression of male-specific cytochrome P450 2c and its mRNA by 3,4,5,3',4',5'-hexachlorobiphenyl in rat liver is not causally related to changes in serum testosterone. 
  • Testicular adenosine 3':5'-monophosphate-dependent protein kinase. Regulation by follicle-stimulating hormone. 
  • The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus. 
  • The assessment of pituitary function. 
  • The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-alpha. 
  • The effect of neonatal exposure to DES and o,p'-DDT on pituitary responsiveness to GnRH in adult castrated rats. 
  • The effect of neonatal exposure to diethylstilbestrol, coumestrol, and beta-sitosterol on pituitary responsiveness and sexually dimorphic nucleus volume in the castrated adult rat. 
  • The effect of neonatal exposure to diethylstilbestrol, genistein, and zearalenone on pituitary responsiveness and sexually dimorphic nucleus volume in the castrated adult rat. 
  • The metabolism of luteinizing hormone. Plasma clearance, urinary excretion, and tissue uptake. 
  • The naturally occurring luteinizing hormone surge is diminished in mice lacking estrogen receptor Beta in the ovary. 
  • The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. 
  • The primary empty sella: clinical and radiographic characteristics and endocrine function. 
  • The roles of placental growth hormone and placental lactogen in the regulation of human fetal growth and development. 
  • The thyroid axis is regulated by NCoR1 via its actions in the pituitary. 
  • The value of basal serum follicle stimulating hormone, luteinizing hormone and oestradiol concentrations following pituitary down-regulation in predicting ovarian response to stimulation with highly purified follicle stimulating hormone. 
  • The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. 
  • Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. 
  • Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation. 
  • Transsphenoidal surgery and diabetes mellitus: An analysis of inpatient data and complications. 
  • Zone electrophoresis and prolactin activity of rat adenohypophysis cultivated in vitro. 
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  Keywords of People

  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor for Research in Molecular Biology, Cell Biology