Plasminogen
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Subject Areas on Research
- A colorimetric assay for releasable plasminogen activator.
- A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function.
- Activation of human plasminogen by urokinase. Partial characterization of a pre-activation peptide.
- Acute reduction of lipoprotein(a) by tissue-type plasminogen activator.
- Alterations in natural anticoagulant levels during allogeneic bone marrow transplantation: a prospective study in 27 patients.
- Analysis of autoantibodies to plasminogen in the serum of patients with rheumatoid arthritis.
- Angiostatin binds ATP synthase on the surface of human endothelial cells.
- Angiostatin directly inhibits human prostate tumor cell invasion by blocking plasminogen binding to its cellular receptor, CD26.
- Association of plasminogen with dipeptidyl peptidase IV and Na+/H+ exchanger isoform NHE3 regulates invasion of human 1-LN prostate tumor cells.
- Binding and endocytosis of alpha 2-macroglobulin-plasmin complexes.
- Binding of human plasminogen to basement-membrane (type IV) collagen.
- Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro.
- Catabolism of streptokinase and polyethylene glycol-streptokinase: evidence for transport of intact forms through the biliary system in the mouse.
- Cell surface adenosine deaminase binds and stimulates plasminogen activation on 1-LN human prostate cancer cells.
- Characterization of the plasminogen receptors of normal and rheumatoid arthritis human synovial fibroblasts.
- Coagulation changes in elective surgery and trauma.
- Comparison of plasminogen binding and activation on extracellular matrices produced by vascular smooth muscle and endothelial cells.
- Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor.
- Effect of desialylation on the biological properties of human plasminogen.
- Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis.
- Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin.
- Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2.
- Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site.
- Heparin oligosaccharides enhance tissue-type plasminogen activator: a correlation between oligosaccharide length and stimulation of plasminogen activation.
- In vitro biosynthesis of plasminogen in a cell-free system directed by mRNA fractions isolated from monkey liver.
- Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells.
- Ionic modulation of the effects of heparin on plasminogen activation by tissue plasminogen activator: the effects of ionic strength, divalent cations, and chloride.
- Kinetic analysis of the effects of heparin and lipoproteins on tissue plasminogen activator mediated plasminogen activation.
- Lipoprotein (a): purification and kinetic analysis.
- Lipoprotein a inhibits streptokinase-mediated activation of human plasminogen.
- Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator.
- Lipoprotein(a) inhibits plasminogen activation in a template-dependent manner.
- Mechanism of activation of human plasminogen by the activator complex, streptokinase-plasmin.
- Mechanism of ancrod anticoagulation. A direct proteolytic effect on fibrin.
- Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.
- Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain.
- Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain.
- Modulation of tissue plasminogen activator-catalyzed plasminogen activation by synthetic peptides derived from the amino-terminal heparin binding domain of fibronectin.
- Molecular abnormalities of human plasminogen isolated from synovial fluid of rheumatoid arthritis patients.
- Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains.
- Neonatal plasminogen displays altered cell surface binding and activation kinetics. Correlation with increased glycosylation of the protein.
- Obesity-related coagulation changes in pregnancy.
- Plasmin binding to the plasminogen receptor enhances catalytic efficiency and activates the receptor for subsequent ligand binding.
- Plasminogen acceleration of urokinase thrombolysis.
- Plasminogen activation stimulates an increase in intracellular calcium in human synovial fibroblasts.
- Plasminogen alleles influence susceptibility to invasive aspergillosis.
- Plasminogen structural domains exhibit different functions when associated with cell surface GRP78 or the voltage-dependent anion channel.
- Protein Corona in Response to Flow: Effect on Protein Concentration and Structure.
- Regulation of plasminogen activation by components of the extracellular matrix.
- Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma.
- Sialic acid content of plasminogen 2 glycoforms as a regulator of fibrinolytic activity. Isolation, carbohydrate analysis, and kinetic characterization of six glycoforms of plasminogen.
- The biochemistry of haemostasis.
- The effect of divalent cations on the conformation and function of human plasminogen.
- The effect of plasmin on the subunit structure of human fibrinogen.
- The effect of substituted laminin A chain-derived peptides on the conformation and activation kinetics of plasminogen.
- The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator.
- The importance of the preactivation peptide in the two-stage mechanism of human plasminogen activation.
- The mechanism of action of angiostatin: can you teach an old dog new tricks?
- The role of carbohydrate in the function of human plasminogen: comparison of the protein obtained from molecular cloning and expression in Escherichia coli and COS cells.
- The temperature-dependent reaction between alpha 2-macroglobulin and streptokinase-plasmin(ogen) complex.
- The voltage-dependent anion channel (VDAC) binds tissue-type plasminogen activator and promotes activation of plasminogen on the cell surface.
- The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells.
- Thrombus lysis by uPA, scuPA and tPA is regulated by plasma TAFI.
- Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells.
- Venous thrombosis in a family with defective release of vascular plasminogen activator and elevated plasma factor VIII/von Willebrand's factor.
- Why is lipoprotein(a) relevant to thrombosis?