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Subject Areas on Research
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1,2,4-Trioxanes as potential antimalarial agents.
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Plasmodium
chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy.
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A Thermal Exhaust Port on the Death Star of Plasmodium falciparum-Infected Erythrocytes.
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A cross-sectional survey of Plasmodium falciparum pfcrt mutant haplotypes in the Democratic Republic of Congo.
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A deep sequencing approach to estimate Plasmodium falciparum complexity of infection (COI) and explore apical membrane antigen 1 diversity.
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A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
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A non-destructive sugar-feeding assay for parasite detection and estimating the extrinsic incubation period of Plasmodium falciparum in individual mosquito vectors.
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A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria.
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Absence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic study.
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Adaptive evolution and fixation of drug-resistant Plasmodium falciparum genotypes in pregnancy-associated malaria: 9-year results from the QuEERPAM study.
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Amodiaquine and sulfadoxine-pyrimethamine as treatment for chloroquine-resistant Plasmodium falciparum in Rwanda.
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An intrinsic oscillator drives the blood stage cycle of the malaria parasite Plasmodium falciparum.
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Antenatal receipt of sulfadoxine-pyrimethamine does not exacerbate pregnancy-associated malaria despite the expansion of drug-resistant Plasmodium falciparum: clinical outcomes from the QuEERPAM study.
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Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
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Antibody signatures of asymptomatic Plasmodium falciparum malaria infections measured from dried blood spots.
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Artemisinin combination therapies and malaria parasite drug resistance: the game is afoot.
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Artemisinin resistance in Plasmodium falciparum malaria.
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Assessing the safety and efficacy of a test-based, targeted donor screening strategy to minimize transfusion transmitted malaria.
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Automated Detection of P. falciparum Using Machine Learning Algorithms with Quantitative Phase Images of Unstained Cells.
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Born to sweet delight: Using natural models of malaria protection to understand and neutralize P. falciparum pathogenesis.
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Characterization of Plasmodium liver stage inhibition by halofuginone.
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Characterization of a UBC13 kinase in Plasmodium falciparum.
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Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children.
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Complexity of the msp2 locus and the severity of childhood malaria, in south-western Nigeria.
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Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria.
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Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.
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Developmental allometry and paediatric malaria.
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Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasites.
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Direct Estimation of Sensitivity of Plasmodium falciparum Rapid Diagnostic Test for Active Case Detection in a High-Transmission Community Setting.
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Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes.
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Discovery of Dual-Stage Malaria Inhibitors with New Targets.
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Discovery of novel targets of quinoline drugs in the human purine binding proteome.
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Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
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Early Endothelial Activation Precedes Glycocalyx Degradation and Microvascular Dysfunction in Experimentally Induced Plasmodium falciparum and Plasmodium vivax Infection.
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Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a systematic review and meta-analysis.
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Effect of three years' seasonal malaria chemoprevention on molecular markers of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine and amodiaquine in Ouelessebougou, Mali.
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Efficacy of chloroquine on Plasmodium falciparum transmitted at Amani, eastern Usambara Mountains, north-east Tanzania: an area where malaria has recently become endemic.
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Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia.
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Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.
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Epidemiology of Plasmodium falciparum Infections in a Semi-Arid Rural African Setting: Evidence from Reactive Case Detection in Northwestern Kenya.
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Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum.
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Exploring the lower thermal limits for development of the human malaria parasite, Plasmodium falciparum.
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Exposure to Diverse Plasmodium falciparum Genotypes Shapes the Risk of Symptomatic Malaria in Incident and Persistent Infections: A Longitudinal Molecular Epidemiologic Study in Kenya.
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Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors.
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Fever in patients with mixed-species malaria.
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Genetic Evidence of Importation of Drug-Resistant Plasmodium falciparum to Guatemala from the Democratic Republic of the Congo.
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Genetic diversity of the msp-1 locus and symptomatic malaria in south-west Nigeria.
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Genotyping cognate Plasmodium falciparum in humans and mosquitoes to estimate onward transmission of asymptomatic infections.
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Glycocalyx Breakdown Is Associated With Severe Disease and Fatal Outcome in Plasmodium falciparum Malaria.
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Griseofulvin impairs intraerythrocytic growth of Plasmodium falciparum through ferrochelatase inhibition but lacks activity in an experimental human infection study.
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Hemoglobin consumption by P. falciparum in individual erythrocytes imaged via quantitative phase spectroscopy.
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Hemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesis.
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High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
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High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya.
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Higher production of peripheral blood macrophage migration inhibitory factor in healthy children with a history of mild malaria relative to children with a history of severe malaria.
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Host iron status and iron supplementation mediate susceptibility to erythrocytic stage Plasmodium falciparum.
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How to train your antibody to fight malaria.
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Hyperendemic malaria transmission in areas of occupation-related travel in the Peruvian Amazon.
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Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.
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Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity.
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Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial Pf
GSK3/Pf
PK6 with Activity against Blood Stage Parasites In Vitro.
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Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum.
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Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast.
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Impact of Sickle Cell Trait Hemoglobin on the Intraerythrocytic Transcriptional Program of Plasmodium falciparum.
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Impact of Sulfadoxine-Pyrimethamine Resistance on Effectiveness of Intermittent Preventive Therapy for Malaria in Pregnancy at Clearing Infections and Preventing Low Birth Weight.
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Impact of asymptomatic Plasmodium falciparum infection on the risk of subsequent symptomatic malaria in a longitudinal cohort in Kenya.
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Impact of intermittent screening and treatment for malaria among school children in Kenya: a cluster randomised trial.
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Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin.
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Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria.
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In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.
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In vivo and in vitro susceptibility to chloroquine of Plasmodium falciparum in Kinshasa and Mbuji-Mayi, Zaire.
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Increased prevalence of dhfr and dhps mutants at delivery in Malawian pregnant women receiving intermittent preventive treatment for malaria.
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Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade.
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Increasing a microscope's effective field of view via overlapped imaging and machine learning.
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Independent lineages of highly sulfadoxine-resistant Plasmodium falciparum haplotypes, eastern Africa.
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Inhibition of endothelial activation: a new way to treat cerebral malaria?
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Interaction between acute diarrhoea and falciparum malaria in Nigerian children.
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Interactions Between Antenatal Sulfadoxine-Pyrimethamine, Drug-Resistant Plasmodium falciparum Parasites, and Delivery Outcomes in Malawi.
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Invasive bacterial and fungal infections among hospitalized HIV-infected and HIV-uninfected children and infants in northern Tanzania.
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It's about Time: Insights into the Modes of Action of Antimalarials.
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Kinetic and Cross-Sectional Studies on the Genesis of Hypoargininemia in Severe Pediatric Plasmodium falciparum Malaria.
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Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imaging.
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Lessons from malaria control to elimination: case study in Hainan and Yunnan provinces.
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Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
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Malaria protection due to sickle haemoglobin depends on parasite genotype.
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Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum.
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Minimal Impact by Antenatal Subpatent Plasmodium falciparum Infections on Delivery Outcomes in Malawian Women: A Cohort Study.
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Modeling asymptomatic infections and work-related human circulation as drivers of unstable malaria transmission in low-prevalence areas: A study in the Northern Peruvian Amazon.
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Modelling the incremental benefit of introducing malaria screening strategies to antenatal care in Africa.
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Molecular malaria epidemiology: mapping and burden estimates for the Democratic Republic of the Congo, 2007.
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Molecular surveillance for drug-resistant Plasmodium falciparum in clinical and subclinical populations from three border regions of Burma/Myanmar: cross-sectional data and a systematic review of resistance studies.
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Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations.
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Overlap Extension Barcoding for the Next Generation Sequencing and Genotyping of Plasmodium falciparum in Individual Patients in Western Kenya.
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Parasite prevalence: a static measure of dynamic infections.
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Parasitologic and clinical efficacy of 25 and 50 mg/kg of chloroquine for treatment of Plasmodium falciparum malaria in Rwandan children.
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Patchy ischemic retinal whitening.
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Pathologic changes associated with fatal Plasmodium falciparum infection in the Bolivian squirrel monkey (Saimiri sciureus boliviensis).
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Permethrin-impregnated curtains and bed-nets prevent malaria in western Kenya.
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Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death.
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Plasma Plasmodium falciparum histidine-rich protein-2 concentrations are associated with malaria severity and mortality in Tanzanian children.
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Plasmodium falciparum Genetic Diversity in Coincident Human and Mosquito Hosts.
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Plasmodium falciparum malaria: band 3 as a possible receptor during invasion of human erythrocytes.
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Plasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo.
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Plasmodium falciparum, anaemia and cognitive and educational performance among school children in an area of moderate malaria transmission: baseline results of a cluster randomized trial on the coast of Kenya.
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Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum.
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Polysome profiling of the malaria parasite Plasmodium falciparum.
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Pooled deep sequencing of Plasmodium falciparum isolates: an efficient and scalable tool to quantify prevailing malaria drug-resistance genotypes.
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Predictors of Plasmodium falciparum Infection in the First Trimester Among Nulliparous Women From Kenya, Zambia, and the Democratic Republic of the Congo.
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Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors.
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Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite.
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Providing lipid-based nutrient supplement during pregnancy does not reduce the risk of maternal P falciparum parasitaemia and reproductive tract infections: a randomised controlled trial.
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Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens.
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Quantification of Plasmodium falciparum histidine-rich protein-2 in cerebrospinal spinal fluid from cerebral malaria patients.
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Quantification of the burden and consequences of pregnancy-associated malaria in the Democratic Republic of the Congo.
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Random Forest Model Predictions Afford Dual-Stage Antimalarial Agents.
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Rapid Diagnostic Test Performance Assessed Using Latent Class Analysis for the Diagnosis of Plasmodium falciparum Placental Malaria.
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Relationship between changing malaria burden and low birth weight in sub-Saharan Africa: A difference-in-differences study via a pair-of-pairs approach.
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Reply to Harrington et al.
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Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase.
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Response of children with Plasmodium falciparum to chloroquine and development of a national malaria treatment policy in Zaire.
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Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics.
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Sexual reproduction and the evolution of microbial pathogens.
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Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes.
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Single-Cell Analysis Reveals Distinct Gene Expression and Heterogeneity in Male and Female Plasmodium falciparum Gametocytes.
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Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
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Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents.
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Suppression of prostaglandin E2 by malaria parasite products and antipyretics promotes overproduction of tumor necrosis factor-alpha: association with the pathogenesis of childhood malarial anemia.
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Systematic comparison of two methods to measure parasite density from malaria blood smears.
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The A581G Mutation in the Gene Encoding Plasmodium falciparum Dihydropteroate Synthetase Reduces the Effectiveness of Sulfadoxine-Pyrimethamine Preventive Therapy in Malawian Pregnant Women.
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The changing landscape of Plasmodium falciparum drug resistance in the Democratic Republic of Congo.
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The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
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The diagnosis of Plasmodium falciparum infection using a new antigen detection system.
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The geography of malaria genetics in the Democratic Republic of Congo: A complex and fragmented landscape.
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Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes.
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Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance.
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Treatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, Conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquine.
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Ultrastructural localization of erythrocyte cytoskeletal and integral membrane proteins in Plasmodium falciparum-infected erythrocytes.
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Using context to improve protein domain identification.
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[LMP-420, a new therapeutic approach for cerebral malaria?].
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Keywords of People