Pneumonia

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  Subject Areas on Research

  • 2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation. 
  • A Phase II Randomized, Double-blind, Multicenter Study to Evaluate Efficacy and Safety of Intravenous Iclaprim Versus Vancomycin for the Treatment of Nosocomial Pneumonia Suspected or Confirmed to be Due to Gram-positive Pathogens. 
  • A clinical syndrome in imported cows subjected to environmental stress in Sudan. 
  • A model to predict risk of postpartum infection after Caesarean delivery. 
  • A multicenter analysis of the ED diagnosis of pneumonia. 
  • A multicenter pilot study of a bronchial valve for the treatment of severe emphysema. 
  • A patient with newly diagnosed melanoma and pulmonary nodules. 
  • A scoring system derived from electronic health records to identify patients at high risk for noninvasive ventilation failure. 
  • ACR Appropriateness Criteria Fever Without Source or Unknown Origin-Child. 
  • Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide-induced lung inflammation. 
  • Acute Adverse Events After Spinal Cord Injury and Their Relationship to Long-term Neurologic and Functional Outcomes: Analysis From the North American Clinical Trials Network for Spinal Cord Injury. 
  • Acute infectious morbidity in multiple gestation. 
  • Adult pneumonia in a general hospital. Etiology and host risk factors. 
  • Advanced Modeling to Predict Pneumonia in Combat Trauma Patients. 
  • Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide. 
  • Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse. 
  • Allogeneic marrow transplantation using fractionated total body irradiation in patients with acute lymphoblastic leukemia in relapse. 
  • Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. 
  • Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis. 
  • Analysis of Factors Associated With In-hospital Mortality in Lung Cancer Chemotherapy Patients With Neutropenia. 
  • Anti-Jo-1 syndrome presenting as cryptogenic organizing pneumonia. 
  • Antibiotic concentrations in human parapneumonic effusions. 
  • Association of Ozone Exposure With Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults. 
  • Association of Pneumonia, Wound Infection, and Sepsis with Clinical Outcomes after Acute Traumatic Spinal Cord Injury. 
  • Association of respiratory viruses with outcomes of severe childhood pneumonia in Botswana. 
  • Associations between Community-Acquired Pneumonia and Proton Pump Inhibitors in the Laryngeal/Voice-Disordered Population. 
  • Associations between Community-Acquired Pneumonia and Proton Pump Inhibitors in the Laryngeal/Voice-Disordered Population. 
  • Atypical pathogens and challenges in community-acquired pneumonia. 
  • Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury. 
  • Carfilzomib, pomalidomide, and dexamethasone for relapsed or refractory myeloma. 
  • Cat germs! Pleuropulmonary pasteurella infection in an old man. 
  • Cause specific mortality patterns among the oldest old: multiple cause of death trends 1968 to 1980. 
  • Cefazolin in the treatment of bacterial pneumonia. 
  • Characteristics of primary care and rates of pediatric hospitalizations in Brazil. 
  • Chest Radiographic Findings and Outcomes of Pneumonia Among Children in Botswana. 
  • Childhood Pneumonia. 
  • Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice. 
  • Clara cells attenuate the inflammatory response through regulation of macrophage behavior. 
  • Clinical, Imaging Findings, Responses, and Outcomes of Patients With Classical Hodgkin Lymphoma and Non-Hodgkin Lymphoma Undergoing Immune Checkpoint Inhibitor Therapy: A Single-Institution Experience. 
  • Coexisting endogenous and exogenous lipoid pneumonia and pulmonary alveolar proteinosis in a patient with neurodevelopmental disease. 
  • Collaborative Quality Improvement Reduces Postoperative Pneumonia After Isolated Coronary Artery Bypass Grafting Surgery. 
  • Comparison of the efficacy of IGIV-C, 10% (caprylate/chromatography) and IGIV-SD, 10% as replacement therapy in primary immune deficiency. A randomized double-blind trial. 
  • Comparisons of ultrafine and fine particles in their associations with biomarkers reflecting physiological pathways. 
  • Compliance with clinical pathways for inpatient care in Chinese public hospitals. 
  • Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses. 
  • Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. 
  • Deep learning for chest radiograph diagnosis: A retrospective comparison of the CheXNeXt algorithm to practicing radiologists. 
  • Determinants of Variation in Pneumonia Rates After Coronary Artery Bypass Grafting. 
  • Development of a Metastatic Spinal Tumor Frailty Index (MSTFI) Using a Nationwide Database and Its Association with Inpatient Morbidity, Mortality, and Length of Stay After Spine Surgery. 
  • Diabetes and early postoperative outcomes following lumbar fusion. 
  • Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection. 
  • Does This Child Have Pneumonia?: The Rational Clinical Examination Systematic Review. 
  • Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy. 
  • Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study. 
  • Effect Of A Large-Scale Social Franchising And Telemedicine Program On Childhood Diarrhea And Pneumonia Outcomes In India. 
  • Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial. 
  • Effect of Haemophilus influenzae Type b and 13-Valent Pneumococcal Conjugate Vaccines on Childhood Pneumonia Hospitalizations and Deaths in Botswana. 
  • Effect of erionite on the pleural mesothelium of the Fischer 344 rat. 
  • Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6. 
  • Effectiveness of the 10-valent pneumococcal conjugate vaccine against radiographic pneumonia among children in rural Bangladesh: A case-control study. 
  • Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis. 
  • Evaluation of a Hospital-Based Pneumonia Nurse Navigator Program. 
  • Evaluation of a new weaning index based on ventilatory endurance and the efficiency of gas exchange. 
  • Evaluation of a social franchising and telemedicine programme and the care provided for childhood diarrhoea and pneumonia, Bihar, India 
  • Factors identified as precipitating hospital admissions for heart failure and clinical outcomes: findings from OPTIMIZE-HF. 
  • Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque. 
  • Feasibility and safety of moderate hypothermia after massive hemispheric infarction. 
  • Femur fractures and lung complications: a prospective randomized study of reaming. 
  • Findings on Chest CT Performed in the Emergency Department in Patients Receiving Immune Checkpoint Inhibitor Therapy: Single-Institution 8-Year Experience in 136 Patients. 
  • Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model. 
  • Fungal diagnostics in pneumonia. 
  • Future Research Directions in Pneumonia. NHLBI Working Group Report. 
  • Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study. 
  • Harmonisation in study design and outcomes in paediatric antibiotic clinical trials: a systematic review. 
  • Has Public Reporting of Hospital Readmission Rates Affected Patient Outcomes?: Analysis of Medicare Claims Data. 
  • High-dose influenza vaccine to reduce clinical outcomes in high-risk cardiovascular patients: Rationale and design of the INVESTED trial. 
  • Histone Deacetylase 7 in Murine Gram-Negative Acute Lung Injury. 
  • Hydrogen Sulfide Prevents and Partially Reverses Ozone-Induced Features of Lung Inflammation and Emphysema in Mice. 
  • Hyperexpansion of Functional Viral-Specific CD8+ T Cells in Lymphopenia-Associated MCMV Pneumonitis. 
  • Hyponatremia in pediatric patients with HIV-1 infection. 
  • Illuminating Lung Inflammation at the Alveolar Capillary Interface. 
  • Imaging of bacterial pulmonary infection in the immunocompetent patient. 
  • Immune Checkpoint Inhibitor Therapy-related Pneumonitis: Patterns and Management. 
  • Impact of a combined pediatric and adult pneumococcal immunization program on adult pneumonia incidence and mortality in Nicaragua. 
  • Improving outcomes after esophagectomy: the importance of preventing postoperative pneumonia. 
  • In-Hospital Mortality in Patients with Idiopathic Pulmonary Fibrosis: A US Cohort Study. 
  • Incidence and severity of acute complications after spinal cord injury. 
  • Incidence, risk factors, and mortality from pneumonia developing late after hematopoietic stem cell transplantation. 
  • Infection related never events in pediatric patients undergoing spinal fusion procedures in United States: prevalence and predictors. 
  • Infections after upper extremity allotransplantation: a worldwide population cohort study, 1998-2017. 
  • Inhaled carbon monoxide and hyperoxic lung injury in rats. 
  • Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus. 
  • Intermittent hypoxia during recovery from neonatal hyperoxic lung injury causes long-term impairment of alveolar development: A new rat model of BPD. 
  • Interpretation of pediatric chest radiographs by non-radiologist clinicians in Botswana using World Health Organization criteria for endpoint pneumonia. 
  • Investigating Mediators of the Poor Pneumonia Outcomes of Human Immunodeficiency Virus-Exposed but Uninfected Children. 
  • Iron supplementation decreases severity of allergic inflammation in murine lung. 
  • Isolated intrapulmonary adenopathy in leukemia. 
  • Kerley B lines in total anomalous pulmonaru venous connection below the diaphragm (type 3). 
  • Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis. 
  • Late complications after marrow transplantation. 
  • Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. 
  • Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality 
  • Long-term results of a postoperative pneumonia prevention program for the inpatient surgical ward. 
  • Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial. 
  • Loss of basal cells precedes bronchiolitis obliterans-like pathological changes in a murine model of chlorine gas inhalation. 
  • Low prevalence of Pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia. 
  • Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis. 
  • Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure. 
  • Macrolides and Pediatric Community-Acquired Pneumonia-Time for a Paradigm Shift? 
  • Management of pneumonia in the nursing home. 
  • Managing toxicities of phosphatidylinositol-3-kinase (PI3K) inhibitors. 
  • Miliary aspergillosis associated with alcoholism. 
  • Mortality and time to extubation in severe hospital-acquired pneumonia. 
  • NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans. 
  • Neisseria meningitidis, a respiratory pathogen? 
  • Neonatal Job's syndrome featuring a vesicular eruption. 
  • Nosocomial infections within the first month of solid organ transplantation. 
  • Novel Mechanisms of Ozone-Induced Pulmonary Inflammation and Resolution, and the Potential Protective Role of Scavenger Receptor BI. 
  • Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice. 
  • Nurse staffing and adverse events in hospitalized children. 
  • Open lung biopsy for the diagnosis of acute, diffuse pulmonary infiltrates in the immunosuppressed patient. 
  • Opportunistic fungal pneumonia. 
  • Organizing pneumonia in mice and men. 
  • Outcomes after esophagectomy: a ten-year prospective cohort. 
  • Outpatient consolidation treatment with clofarabine in a phase 2 study of older adult patients with previously untreated acute myelogenous leukemia. 
  • Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen. 
  • PROLONGED RUPTURE OF FETAL MEMBRANES. 
  • PROPHETIC: Prospective Identification of Pneumonia in Hospitalized Patients in the ICU. 
  • Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery. 
  • Patient Portals: Who uses them? What features do they use? And do they reduce hospital readmissions? 
  • Peripheral middle lobe syndrome. 
  • Platelet activation and pneumonia: is soluble p-selectin the right marker? 
  • Pleural fluid in infants and children. 
  • Pneumonia after cardiac surgery: Experience of the National Institutes of Health/Canadian Institutes of Health Research Cardiothoracic Surgical Trials Network. 
  • Pneumonia and respiratory infections in Down syndrome: A scoping review of the literature. 
  • Pneumonia due to Fonsecaea pedrosoi and cerebral abscesses due to Emericella nidulans in a bone marrow transplant recipient. 
  • Pneumonia in bone marrow transplant patients. 
  • Pneumonia: Hiding in Plain (Film) Sight. 
  • Precipitating Clinical Factors, Heart Failure Characterization, and Outcomes in Patients Hospitalized With Heart Failure With Reduced, Borderline, and Preserved Ejection Fraction. 
  • Presence of gingivitis and periodontitis significantly increases hospital charges in patients undergoing heart valve surgery. 
  • Procalcitonin: The Right Answer but to Which Question? 
  • Pulmonary cryptococcosis in patients without HIV infection: factors associated with disseminated disease. 
  • Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats. 
  • Pulmonary effects of synthetic marijuana: chest radiography and CT findings. 
  • Pulmonary infiltrates and eosinophilia in an FK 506 liver transplant recipient. 
  • Pulmonary toxicity after exposure to military-relevant heavy metal tungsten alloy particles. 
  • Quinolone safety and efficacy more important than potency. 
  • Quinolones for community-acquired pneumonia. 
  • RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. 
  • Radiographic findings in patients with acute respiratory distress syndrome. 
  • Radiology of acute diffuse lung disease in the immunocompetent host. 
  • Radionuclide quantitation of lung function in patients with pulmonary disorders. 
  • Re: "Community-acquired pneumonia". 
  • Recent advances in the epidemiology, prevention, diagnosis, and treatment of fungal pneumonia. 
  • Recognition of early mortality in multiple myeloma by a prediction matrix. 
  • Recurrent Use of VV ECMO in Refractory Hypoxemia After Penetrating Lung Injury and Multifocal Pneumonia in a Single Individual's ICU Stay. 
  • Recurrent infection, chronic diarrhea, and failure to thrive in a seven-month-old infant. 
  • Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. 
  • Reducing hospital morbidity and mortality following esophagectomy. 
  • Rejection criteria for endotracheal aspirates from adults. 
  • Rejection criteria for endotracheal aspirates from pediatric patients. 
  • Relapsing polychondritis affecting the lower respiratory tract. 
  • Relationship between patient satisfaction with inpatient care and hospital readmission within 30 days. 
  • Relationship between physician financial incentives and clinical pathway compliance: a cross-sectional study of 18 public hospitals in China. 
  • Reoperation for bleeding in patients undergoing coronary artery bypass surgery: incidence, risk factors, time trends, and outcomes. 
  • Repetitive Ozone Exposures and Evaluation of Pulmonary Inflammation and Remodeling in Diabetic Mouse Strains. 
  • Rhodococcus equi causing human pulmonary infection: review of 29 cases. 
  • Risk factors for mortality in patients admitted to intensive care units with pneumonia. 
  • Risk factors for nosocomial pneumonia in the elderly. 
  • Risk factors for nosocomial pneumonia: comparing adult critical-care populations. 
  • Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury. 
  • Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. 
  • Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema. 
  • SPINAL OR GENERAL ANESTHESIA FOR INGUINAL HERNIA REPAIR?A COMPARISON OF CERTAIN COMPLICATIONS IN A CONTROLLED SERIES. 
  • Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors. 
  • Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review. 
  • Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide. 
  • Six subphenotypes in septic shock: Latent class analysis of the PROWESS Shock study. 
  • Specialized Pro-Resolving Lipid Mediators Regulate Ozone-Induced Pulmonary and Systemic Inflammation. 
  • Suboptimal HIV Testing Among Patients Admitted With Pneumonia: A Missed Opportunity. 
  • Successful DNA immunization against measles: neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles. 
  • Successful treatment of Ochroconis gallopavum infection in an immunocompetent host. 
  • TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. 
  • Telavancin for hospital-acquired pneumonia: clinical response and 28-day survival. 
  • Temporal trends in U. S. multiple cause of death mortality data: 1968 to 1977. 
  • The ARREST Pneumonia Clinical Trial. Rationale and Design. 
  • The cardiopulmonary effects of ambient air pollution and mechanistic pathways: a comparative hierarchical pathway analysis. 
  • The characteristics and mortality of outpatient-acquired pneumonia. 
  • The effect of exposure to wood smoke on outcomes of childhood pneumonia in Botswana. 
  • The evaluation of screening methods to identify medically unnecessary hospital stay for patients with pneumonia. 
  • The know-do gap in quality of health care for childhood diarrhea and pneumonia in rural India. 
  • The lung is protected from spontaneous inflammation by autophagy in myeloid cells. 
  • Thoracoscopic lobectomy: a safe and effective strategy for patients receiving induction therapy for non-small cell lung cancer. 
  • Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. 
  • Ticlopidine-associated pancytopenia: implications of an acetylsalicylic acid alternative. 
  • Timing of Complications Occurring Within 30 Days After Adult Spinal Deformity Surgery. 
  • Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide. 
  • Total shoulder arthroplasty in patients with HIV infection: complications, comorbidities, and trends. 
  • Towards precision medicine: Accurate predictive modeling of infectious complications in combat casualties. 
  • Transthoracic versus transhiatal esophagectomy: a prospective study of 945 patients. 
  • Treatment Failures and Excess Mortality Among HIV-Exposed, Uninfected Children With Pneumonia. 
  • Umbralisib, a novel PI3Kδ and casein kinase-1ε inhibitor, in relapsed or refractory chronic lymphocytic leukaemia and lymphoma: an open-label, phase 1, dose-escalation, first-in-human study. 
  • Using a Retrospective Secondary Data Analysis to Identify Risk Factors for Pulmonary Complications in Trauma Patients in Pietermaritzburg, South Africa. 
  • Ventilator-associated pneumonia: the role of ventilator management strategies. 
  • Video-assisted wedge resection and local radiotherapy for peripheral lung cancer in high-risk patients: the Cancer and Leukemia Group B (CALGB) 9335, a phase II, multi-institutional cooperative group study. 
  • When It Comes to Alternaria, Instant CARMA's Gonna Get You. 
  • Which Complications Matter Most? Prioritizing Quality Improvement in Emergency General Surgery. 
  • Xenon-133 measurement of regional ventilation. 
  • Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. 
  • [Etiologic characteristics of adult patients with community-acquired pneumonia in Beijing]. 
  • [Finding of so-called L E cells in a pneumonitis focus before death from acute lupus erythematosus]. 
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  Keywords of People

  • Bradford, William Dalton, Professor of Pathology, Pathology
  • Chen, Jun, Professor of Medicine, Duke Cancer Institute
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Jordt, Sven Eric, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology
  • Kraft, Bryan David, Adjunct Assistant Professor in the Department of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • McConnell, Eleanor Schildwachter, Associate Professor in the School of Nursing, School of Nursing
  • Mohanan, Manoj, Associate Professor in the Sanford School of Public Policy, Economics
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology