Poly I-C
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Subject Areas on Research
- Antiviral activity of mismatched double-stranded RNA against human immunodeficiency virus in vitro.
- Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport.
- CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements.
- Clinical, immunological, and virological effects of ampligen, a mismatched double-stranded RNA, in patients with AIDS or AIDS-related complex.
- Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.
- Development of functional diversity in mouse macrophages. Mutual exclusion of two phenotypic states.
- Effects of progesterone and estradiol sex hormones on the release of microparticles by RAW 264.7 macrophages stimulated by Poly(I:C).
- Functional switching of macrophage responses to tumor necrosis factor-alpha (TNF alpha) by interferons. Implications for the pleiotropic activities of TNF alpha.
- Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands.
- Inhibition of HIV-1 proviral DNA synthesis and RNA accumulation by mismatched dsRNA.
- Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant.
- Interferon increases the abundance of submembranous microfilaments in HeLa-S3 cells in suspension culture.
- Mismatched double-stranded RNA (ampligen) reduces concentration of zidovudine (azidothymidine) required for in-vitro inhibition of human immunodeficiency virus.
- Mismatched dsRNA (ampligen) induces protection against genomic variants of the human immunodeficiency virus type 1 (HIV-1) in a multiplicity of target cells.
- Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide.
- Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.
- Polyribonucleotides induce nitric oxide production by human monocyte-derived macrophages.
- Postinfection therapy of arbovirus infections in mice.
- Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung.
- Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice.
- Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses.
- Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
- TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk.
- TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles.
- The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis.
- The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid.
- The release of microparticles by RAW 264.7 macrophage cells stimulated with TLR ligands.
- The role of IFN-alpha and nitric oxide in the release of HMGB1 by RAW 264.7 cells stimulated with polyinosinic-polycytidylic acid or lipopolysaccharide.
- Toll-like receptor 3 and geographic atrophy in age-related macular degeneration.
- Treatment of intracranial alphavirus infections in mice by a combination of specific antibodies and an interferon inducer.
- Tumor necrosis factor-alpha-induced lung injury and its modulation by synthetic polynucleotide: a physiologic-morphometric analysis.