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Subject Areas on Research
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A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP5+, Synergizes with Carboplatin in Treatment of Chemoresistant Ovarian Cell Line.
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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics.
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A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats.
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A mouse model of familial porphyria cutanea tarda.
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A potent superoxide dismutase mimic: manganese beta-octabromo-meso-tetrakis-(N-methylpyridinium-4-yl) porphyrin.
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Adverse reaction characterized by chest pain, shortness of breath, and syncope associated with verteporfin (visudyne).
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Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity.
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An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.
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An iron tetrahydroporphyrin prosthetic group common to both assimilatory and dissimilatory sulfite reductases.
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Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin.
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Antibody-targeted photodynamic therapy.
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Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes.
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Black stool. Some light on a dark subject.
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Boronic acid porphyrin receptor for ginsenoside sensing.
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Broad spectral domain fluorescence wavelength modulation of visible and near-infrared emissive polymersomes.
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Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
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Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues.
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Chelation, formulation, encapsulation, retention, and in vivo biodistribution of hydrophobic nanoparticles labelled with 57
Co-porphyrin: Oleylamine ensures stable chelation of cobalt in nanoparticles that accumulate in tumors.
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Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection.
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De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex.
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De novo design of a hyperstable non-natural protein-ligand complex with sub-Å accuracy.
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De novo design of a single-chain diphenylporphyrin metalloprotein.
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Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.
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Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate.
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Detection of organophosphate flame retardants in furniture foam and U.S. house dust.
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Determination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics.
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Development of a fluorescence detection system using optical parametric oscillator (OPO) laser excitation for in vivo diagnosis.
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Direct evaluation of electronic coupling mediated by hydrogen bonds: implications for biological electron transfer.
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Driving ability reported by neovascular age-related macular degeneration patients after treatment with ranibizumab.
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Effects of Manganese Porphyrins on Cellular Sulfur Metabolism.
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Efficacy and Safety of Ranibizumab With or Without Verteporfin Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: A Randomized Clinical Trial.
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Encapsulation and retention of chelated-copper inside hydrophobic nanoparticles: Liquid cored nanoparticles show better retention than a solid core formulation.
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Ethyne-bridged (porphinato)zinc(II)-(porphinato)iron(III) complexes: phenomenological dependence of excited-state dynamics upon (porphinato)iron electronic structure.
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Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models.
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Exceptional near-infrared fluorescence quantum yields and excited-state absorptivity of highly conjugated porphyrin arrays.
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Flexible digital signal processing architecture for narrowband and spread-spectrum lock-in detection in multiphoton microscopy and time-resolved spectroscopy
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From ionic liquids to supramolecular polymers.
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Functional changes after photodynamic therapy with verteporfin.
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Generalized Mulliken-Hush analysis of electronic coupling interactions in compressed pi-stacked porphyrin-bridge-quinone systems.
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H2
O2
-Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways.
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High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coli.
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Highly conjugated, acetylenyl bridged porphyrins: new models for light-harvesting antenna systems.
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Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.
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Incorporation of designed extended chromophores into amphiphilic 4-helix bundle peptides for nonlinear optical biomolecular materials.
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Incorporation of tyrosine and glutamine residues into the soluble guanylate cyclase heme distal pocket alters NO and O2 binding.
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Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.
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Isocoproporphyrin: nuclear-magnetic-resonance-and mass-spectral methods for the determination of porphyrin structure.
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Isomeric N-alkylpyridylporphyrins and their Zn(II) complexes: inactive as SOD mimics but powerful photosensitizers.
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Macular translocation surgery with 360-degree peripheral retinectomy following ocular photodynamic therapy of choroidal neovascularization.
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Manganese Porphyrin and Radiotherapy Improves Local Tumor Response and Overall Survival in Orthotopic Murine Mammary Carcinoma Models.
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Manganese porphyrins and related compounds as mimics of superoxide dismutase.
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Manganese superoxide dismutase, MnSOD and its mimics.
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Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury.
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Mn porphyrins as a novel treatment targeting sickle cell NOXs to reverse and prevent acute vaso-occlusion in vivo.
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Modular nanotransporters: a multipurpose in vivo working platform for targeted drug delivery.
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Neuroblastoma grafts are noninvasively removed within mouse neocortex by selective laser activation of intracellular photolytic chromophore.
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Neuropsychiatric manifestations of porphyria.
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New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.
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Noninvasively induced degeneration of neocortical pyramidal neurons in vivo: selective targeting by laser activation of retrogradely transported photolytic chromophore.
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Novel amphiphilic cationic porphyrin and its Ag(II) complex as potential anticancer agents.
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Optical coherence tomography following photodynamic therapy with verteporfin for subfoveal predominantly classic choroidal neovascularization.
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Orientational Dependence of Cofacial Porphyrin-Quinone Electronic Interactions within the Strong Coupling Regime
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Photodynamic therapy for predominantly hemorrhagic lesions in neovascular age-related macular degeneration.
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Photodynamic treatment in a rabbit model of glaucoma surgery.
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Photoinitiated destruction of composite porphyrin-protein polymersomes.
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Photosensitizing action of isomeric zinc N-methylpyridylporphyrins in human carcinoma cells.
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Quasi-ohmic single molecule charge transport through highly conjugated meso-to-meso ethyne-bridged porphyrin wires.
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RADIANCE: a randomized controlled study of ranibizumab in patients with choroidal neovascularization secondary to pathologic myopia.
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Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration (FOCUS): year 2 results.
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Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.
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Real-Time Visualization of the Precipitation and Phase Behavior of Octaethylporphyrin in Lipid Microparticles.
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Redox potential determines the reaction mechanism of HNO donors with Mn and Fe porphyrins: defining the better traps.
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Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. VI. The reaction of carbon monoxide with the Escherichia coli holoenzyme, the hemoprotein, and free siroheme.
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Regression of extrafoveal choroidal osteoma following photodynamic therapy.
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Regulating Singlet-Triplet Energy Gaps through Substituent-Driven Modulation of the Exchange and Coulomb Interactions.
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Resolution of advanced cystoid macular edema following photodynamic therapy for choroidal hemangioma.
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Resonance Raman studies of Escherichia coli sulfite reductase hemoprotein. 1. Siroheme vibrational modes.
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Retrospective review of eyes with neovascular age-related macular degeneration treated with photodynamic therapy with verteporfin and intravitreal triamcinolone.
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Rotational isomers of N-alkylpyridylporphyrins and their metal complexes. HPLC separation, (1)H NMR and X-ray structural characterization, electrochemistry, and catalysis of O(2)(.-) disproportionation.
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Selective laser-activated lesioning of prelabeled fetal hippocampal grafts by intracellular photolytic chromophore.
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Sensing membrane stress with near IR-emissive porphyrins.
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Shear stress induces ATP-independent transient nitric oxide release from vascular endothelial cells, measured directly with a porphyrinic microsensor.
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Siroheme and sirohydrochlorin. The basis for a new type of porphyrin-related prosthetic group common to both assimilatory and dissimilatory sulfite reductases.
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Sirohydrochlorin. Prosthetic group of a sulfite reductase enzyme and its role in the biosynthesis of vitamin B12.
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Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor.
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Structural studies of amphiphilic 4-helix bundle peptides incorporating designed extended chromophores for nonlinear optical biomolecular materials.
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Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential.
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Superoxidized states of Escherichia coli sulfite reductase heme protein subunit.
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Synthetic Control of Exciton Dynamics in Bioinspired Cofacial Porphyrin Dimers.
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THREE-YEAR RESULTS OF POLYPOIDAL CHOROIDAL VASCULOPATHY TREATED WITH PHOTODYNAMIC THERAPY: Retrospective Study and Systematic Review.
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Targeting mitochondria by Zn(II)N-alkylpyridylporphyrins: the impact of compound sub-mitochondrial partition on cell respiration and overall photodynamic efficacy.
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The nature of aqueous tunneling pathways between electron-transfer proteins.
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Thiol regulation by Mn porphyrins, commonly known as SOD mimics.
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Water exchange rates of water-soluble manganese(III) porphyrins of therapeutical potential.
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Keywords of People