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Subject Areas on Research
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A randomized, double-blind, placebo-controlled trial of pregnenolone for bipolar depression.
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Adrenal physiology and pharmacology.
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Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits.
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Assessment of pregnenolone effects on alcohol intake and preference in male alcohol preferring (P) rats.
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Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage.
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Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy?
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DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.
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Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial.
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Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.
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Metabolites of progesterone in urine compared with progesterone in ovarian venous plasma of the cycling domestic sow.
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Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice.
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Neurosteroid Levels in Patients With Bipolar Disorder and a History of Cannabis Use Disorders.
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Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions.
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Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence.
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Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice.
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Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?
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Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia.
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Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.
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Protein kinase stimulation of a reconstituted cholesterol side chain cleavage enzyme system in the bovine corpus luteum.
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Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.
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The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
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The steroid profile of a virilizing ovarian tumor.
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Keywords of People