Prions
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Subject Areas on Research
- A novel PRNP-P105S mutation associated with atypical prion disease and a rare PrPSc conformation.
- A novel human disease with abnormal prion protein sensitive to protease.
- Apolipoprotein E in Creutzfeldt-Jakob disease.
- De novo appearance and "strain" formation of yeast prion [PSI+] are regulated by the heat-shock transcription factor.
- Detecting prion protein gene mutations by denaturing gradient gel electrophoresis.
- Evidence for synergistic effects of PRNP and ATP7B mutations in severe neuropsychiatric deterioration.
- Evolution of budding yeast prion-determinant sequences across diverse fungi.
- Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: where to from here?
- Parkinson's disease from the gut.
- Preimplantation genetic diagnosis (PGD) for genetic prion disorder due to F198S mutation in the PRNP gene.
- Prion disease diagnosis by proteomic profiling.
- Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration.
- Protein amyloidose misfolding: mechanisms, detection, and pathological implications.
- Radical changes in beta-amyloid form and function.
- Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease.
- Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.