Prostaglandins

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  Subject Areas on Research

  • A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. 
  • Anaphylactic and anaphylactoid reactions. A review. 
  • Blockade of thromboxane/endoperoxide receptor-mediated responses in the pulmonary vascular bed of the cat by sulotroban. 
  • Comparative changes in ventilatory dead space following micro and massive pulmonary emboli. 
  • Comparative effectiveness and safety of drug therapy for pulmonary arterial hypertension: a systematic review and meta-analysis. 
  • Comparison of prostaglandin F2alpha and hypertonic saline for induction of midtrimester abortion. 
  • Continuous extraovular administration of prostaglandin F2alpha for midtrimester abortion. 
  • Continuous prostaglandin-F 2 infusion for middle-trimester abortion. 
  • Contributions of neuroendocrine and local autocrine-paracrine mechanisms to the pathophysiology and pharmacology of congestive heart failure. 
  • Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning. 
  • Effector mechanisms in transplant rejection. 
  • Effects of diazoxide and beta adrenergic drugs on spontaneous and induced uterine activity in the pregnant baboon. 
  • Effects of prostaglandin F 2 , oxytocin, and ethanol on the uterus of the pregnant baboon. 
  • Effects of two nonsteroidal anti-inflammatory drugs, indomethacin and oxaprozin, on the kidney. 
  • Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice. 
  • Epidermal growth factor alters metabolism of inositol lipids and activity of protein kinase C in mouse embryo palate mesenchyme cells. 
  • Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. 
  • Functional role of thromboxane production by acutely rejecting renal allografts in rats. 
  • High-protein feeding stimulates renal thromboxane production in rats with streptozocin-induced diabetes. 
  • Hormonal activation of adenylate cyclase in macrophage membranes is regulated by guanine nucleotides. 
  • Human melanoma-mediated inhibition of autologous CD4+ helper tumor-infiltrating lymphocyte growth in vitro. 
  • Induction of labor with oral prostaglandin E2. 
  • Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. 
  • Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels. 
  • Kinetic measurements of the release of prostaglandins from perfused rat lungs. 
  • Management of failed prostaglandin abortions. 
  • Mechanism of bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells. 
  • Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism. 
  • Mediators of the chemotaxis of mononuclear leucocytes. 
  • Metabolism of N-alkyl compounds during the biosynthesis of prostaglandins. N-Dealkylation during prostaglandin biosynthesis. 
  • Midtrimester abortion induced by serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha. 
  • Midtrimester abortion induced with a single intra-amniotic instillation of prostaglandin F2 alpha. 
  • Mixed signals: development of the testis. 
  • Necrotizing enterocolitis in infants with ductal-dependent congenital heart disease. 
  • No Evidence of Cardiovascular Harm of Nonsteroidal Anti-Inflammatory Use During Coronary Artery Bypass: Post-hoc Results From Two Large Multicenter Randomized Trials 
  • Obstructive nephropathy in the rat: possible roles for the renin-angiotensin system, prostaglandins, and thromboxanes in postobstructive renal function. 
  • Prostaglandins and inflammation: enhancement of monocyte chemotactic responsiveness by prostaglandin E2. 
  • Prostaglandins in severe congestive heart failure. Relation to activation of the renin--angiotensin system and hyponatremia. 
  • Prostaglandins modulate hormonal effects on rabbit myometrial alpha 1-adrenergic responses. 
  • Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release. 
  • Regulation of the prostaglandin enzymatic system by estradiol and progesterone in nonpregnant sheep cervix. 
  • Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production. 
  • Role of nonenzymatically generated prostanoid, 8-iso-PGF2 alpha, in pulmonary oxygen toxicity. 
  • Role of thromboxane A2 in the induction of apoptosis of immature thymocytes by lipopolysaccharide. 
  • Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor. 
  • Sufficient progesterone-priming prior to estradiol stimulation is required for optimal induction of the cervical prostaglandin system in pregnant sheep at 0.7 gestations. 
  • The effect of medical therapy on IOP control in Ghana. 
  • The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background. 
  • The pulmonary surfactant system. 
  • Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs. 
  • Transforming growth factor-beta inhibits prostaglandin production in amnion and A431 cells. 
  • Vascular and renal prostaglandins as counter-regulatory systems in heart failure. 
  • Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. 
  • Vasopressin-mediated forearm vasodilation in normal humans. Evidence for a vascular vasopressin V2 receptor. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology