Prostate

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  Subject Areas on Research

  • 3-D computer visualization and interactive prostate biopsy simulation leads to an improved systematic technique for the detection of prostate cancer: clinical correlation. 
  • 80 is the new 60: implications of irrational exuberance regarding longevity on prostate cancer treatment decisions. 
  • A Case of Fatal Clostridial Necrotizing Fasciitis After Radical Prostatectomy. 
  • A Multi-Institutional Prospective Trial Confirms Noninvasive Blood Test Maintains Predictive Value in African American Men. 
  • A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers. 
  • A coaxial microwave applicator for transurethral hyperthermia of the prostate. 
  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. 
  • A novel conditionally replicative adenovirus vector targeting telomerase-positive tumor cells. 
  • A novel neoplastic primary tumor-derived human prostate epithelial cell line. 
  • A phase 3, placebo controlled study of the safety and efficacy of avanafil for the treatment of erectile dysfunction after nerve sparing radical prostatectomy. 
  • A polymorphism of the 5 alpha-reductase gene and its association with prostate cancer: a case-control analysis. 
  • A pretreatment nomogram for prediction of biochemical failure after primary cryoablation of the prostate. 
  • A quantitative method for measuring gene expression magnitude and volume delivered by gene therapy vectors. 
  • A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion. 
  • A three-dimensional deformable model for segmentation of human prostate from ultrasound images. 
  • ACR appropriateness criteria on external beam radiation therapy treatment planning for clinically localized prostate cancer expert panel on radiation oncology--prostate. 
  • Abdominal obesity as risk factor for prostate cancer diagnosis and high grade disease: a prospective multicenter Italian cohort study. 
  • Acoustic radiation force impulse imaging of human prostates ex vivo. 
  • Acoustic radiation force impulse imaging of human prostates: initial in vivo demonstration. 
  • Activation of the PKB/Akt pathway in histological benign prostatic tissue adjacent to the primary malignant lesions. 
  • Active surveillance for prostate cancer: can we modernize contemporary protocols to improve patient selection and outcomes in the focal therapy era? 
  • Adenocarcinoma of the prostate. Part II: Tissue prognosticators. 
  • Adrenocortical hyperplasia occurring with metastatic carcinoma of the prostate: report of a case exhibiting increased urinary aldosterone and glucocorticoid excretion. 
  • Adverse pathology and undetectable ultrasensitive prostate-specific antigen after radical prostatectomy: is adjuvant radiation warranted? 
  • After radical retropubic prostatectomy 'insignificant' prostate cancer has a risk of progression similar to low-risk 'significant' cancer. 
  • Alcohol intake increases high-grade prostate cancer risk among men taking dutasteride in the REDUCE trial. 
  • An automated intensity-weighted brachytherapy seed localization algorithm. 
  • An automatic CT-guided adaptive radiation therapy technique by online modification of multileaf collimator leaf positions for prostate cancer. 
  • Anatomy of cavernous nerves distal to prostate: microdissection study in adult male cadavers. 
  • Androgen ablation promotes neuroendocrine cell differentiation in dog and human prostate. 
  • Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line. 
  • Androgen control of an inhibitory modulator of phosphodiesterase in rat epididymis and prostate. 
  • Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers. 
  • Androgen-independent prostate cancer progression in the TRAMP model. 
  • Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. 
  • Angiogenesis, p53, bcl-2 and Ki-67 in the progression of prostate cancer after radical prostatectomy. 
  • Anterior gland focal cryoablation: proof-of-concept primary prostate cancer treatment in select men with localized anterior cancers detected by multi-parametric magnetic resonance imaging. 
  • Antigenic activity of human urothelial tissue. 
  • Antitumor immunity can be uncoupled from autoimmunity following heat shock protein 70-mediated inflammatory killing of normal pancreas. 
  • Apical surgical margins status in robot-assisted laparoscopic radical prostatectomy does not depend on disease characteristics. 
  • Application of dose compensation in image-guided radiotherapy of prostate cancer. 
  • Arc-modulated radiation therapy based on linear models. 
  • Are repeat prostate biopsies safe? A cohort analysis from the SEARCH database. 
  • Aspiration biopsy of prostate. 
  • Assessing clinically significant prostate cancer: Diagnostic properties of multiparametric magnetic resonance imaging compared to three-dimensional transperineal template mapping histopathology. 
  • Association between Agent Orange and prostate cancer: a pilot case-control study. 
  • Association between family history of prostate cancer and positive biopsies in a Brazilian screening program. 
  • Association between preoperative erectile dysfunction and prostate cancer features--an analysis from the Duke Prostate Center Database. 
  • Association of prostate-specific antigen doubling time and cancer in men undergoing repeat prostate biopsy. 
  • Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor. 
  • Autonomic nerve development contributes to prostate cancer progression. 
  • B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging. 
  • Basal cell hyperplasia in the peripheral zone of the prostate. 
  • Baseline Prostate Atrophy is Associated with Reduced Risk of Prostate Cancer in Men Undergoing Repeat Prostate Biopsy. 
  • Benign prostatic hypertrophy and uterine leiomyomas: analogous or dissimilar diseases? 
  • Bilateral focal ablation of prostate tissue using low-energy direct current (LEDC): a preclinical canine study. 
  • Biologically effective dose (BED) correlation with biochemical control after low-dose rate prostate brachytherapy for clinically low-risk prostate cancer. 
  • Biopsy indication--a predictor of pathologic stage among men with preoperative serum PSA levels of 4.0 ng/mL or less and T1c disease. 
  • Body mass index, prostate weight and transrectal ultrasound prostate volume accuracy. 
  • Can RECIST response predict success in phase 3 trials in men with metastatic castration-resistant prostate cancer? 
  • Can the conventional sextant prostate biopsy accurately predict unilateral prostate cancer in low-risk, localized, prostate cancer? 
  • Central zone lesions on magnetic resonance imaging: Should we be concerned? 
  • Characterization of a "low-risk" cohort of grade group 2 prostate cancer patients: Results from the Shared Equal Access Regional Cancer Hospital database. 
  • Characterization of a new model of human prostatic cancer: the multicellular tumor spheroid. 
  • Characterization of alpha-1 adrenoceptor subtypes in human and canine prostate membranes. 
  • Characterization of insulin-like growth factor-binding protein-related proteins (IGFBP-rPs) 1, 2, and 3 in human prostate epithelial cells: potential roles for IGFBP-rP1 and 2 in senescence of the prostatic epithelium. 
  • Characterizing stiffness of human prostates using acoustic radiation force. 
  • Chromosomal instability of SV40-transformed human prostatic epithelial cell lines. 
  • Clarifying the Relative Impacts of Vascular and Nerve Injury That Culminate in Erectile Dysfunction in a Pilot Study Using a Rat Model of Prostate Irradiation and a Thrombopoietin Mimetic. 
  • Clinical and pathologic outcome after radical prostatectomy for prostate cancer patients with a preoperative Gleason sum of 8 to 10. 
  • Clinical utility of percent prostate needle biopsy tissue with cancer cutpoints to risk stratify patients before radical prostatectomy. 
  • Combination of transurethral and interstitial ultrasound applicators for high-temperature prostate thermal therapy. 
  • Combining prostate specific antigen with cancer and gland volume to predict more reliably pathological stage: the influence of prostate specific antigen cancer density. 
  • Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer. 
  • Comparison of percentage of total prostate needle biopsy tissue with cancer to percentage of cores with cancer for predicting PSA recurrence after radical prostatectomy: results from the SEARCH database. 
  • Comparison of preoperative prostate specific antigen density and prostate specific antigen for predicting recurrence after radical prostatectomy: results from the search data base. 
  • Comparison of treatment techniques for conformal radiotherapy of the prostate using dose-volume histograms and normal tissue complication probabilities. 
  • Comparison of ultrasound-guided biopsies and prostatectomy specimens: predictive accuracy of Gleason score and tumor site. 
  • Computed high b-value diffusion-weighted imaging improves lesion contrast and conspicuity in prostate cancer. 
  • Construction and analysis of protein-protein interaction networks based on proteomics data of prostate cancer. 
  • Contemporary role of systematic prostate biopsies: indications, techniques, and implications for patient care. 
  • Correlation of DNA ploidy and histologic diagnosis from prostate core-needle biopsies: is DNA ploidy more sensitive than histology for the diagnosis of carcinoma in small specimens? 
  • Correlation of prostate needle biopsy and radical prostatectomy Gleason grade in academic and community settings. 
  • Cost comparison of radical retropubic and radical perineal prostatectomy: single institution experience. 
  • Cryptococcosis. 
  • DHX15 is up-regulated in castration-resistant prostate cancer and required for androgen receptor sensitivity to low DHT concentrations. 
  • Daily bone alignment with limited repeat CT correction rivals daily ultrasound alignment for prostate radiotherapy. 
  • Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice. 
  • Defining the Incremental Utility of Prostate Multiparametric Magnetic Resonance Imaging at Standard and Specialized Read in Predicting Extracapsular Extension of Prostate Cancer. 
  • Defining the ideal cutpoint for determining PSA recurrence after radical prostatectomy. Prostate-specific antigen. 
  • Definitive external beam irradiation in stage T1 and T2 carcinoma of the prostate. American College of Radiology. ACR Appropriateness Criteria. 
  • Detection of oncornavirus antigenic activity in human urothelial tissues. 
  • Detection of previously unidentified metastatic disease as a leading cause of screening failure in a phase III trial of zibotentan versus placebo in patients with nonmetastatic, castration resistant prostate cancer. 
  • Detection of prostate cancer with multiparametric MRI (mpMRI): effect of dedicated reader education on accuracy and confidence of index and anterior cancer diagnosis. 
  • Development and clinical evaluation of a three-dimensional cone-beam computed tomography estimation method using a deformation field map. 
  • Developmental biology. Branching takes nerve. 
  • Diagnostic accuracy of prostate needle biopsy. 
  • Differential immunoreactivity of her-2/neu oncoprotein in prostatic tissues. 
  • Differential properties among clones of simian virus 40-transformed human epithelial cells. 
  • Diseases of the prostate. 
  • Dissecting the dynamics of serum prostate-specific antigen. 
  • Distinct function of estrogen receptor α in smooth muscle and fibroblast cells in prostate development. 
  • Do racial differences in prostate size explain higher serum prostate-specific antigen concentrations among black men? 
  • Does Early Prostate Specific Antigen Doubling Time after Radical Prostatectomy, Calculated Prior to Prostate Specific Antigen Recurrence, Correlate with Prostate Cancer Outcomes? A Report from the SEARCH Database Group. 
  • Does Prostate Size Predict the Development of Incident Lower Urinary Tract Symptoms in Men with Mild to No Current Symptoms? Results from the REDUCE Trial. 
  • Does prior benign prostate biopsy predict outcome for patients treated with radical perineal prostatectomy? 
  • Dosimetric comparison of four target alignment methods for prostate cancer radiotherapy. 
  • Dosimetric effect of intrafraction motion and residual setup error for hypofractionated prostate intensity-modulated radiotherapy with online cone beam computed tomography image guidance. 
  • E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer. 
  • ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells. 
  • Early-Life Alcohol Intake and High-Grade Prostate Cancer: Results from an Equal-Access, Racially Diverse Biopsy Cohort. 
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  • Effects of neoadjuvant hormonal therapy on prostate biopsy results after (125)I and (103)Pd seed implantation. 
  • Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients. 
  • Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy. 
  • Endorectal surface coil MR imaging of prostatic carcinoma with the inversion-recovery sequence. 
  • Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice. 
  • Erectile function outcome reporting after clinically localized prostate cancer treatment. 
  • Establishing the distribution of satellite lesions in intermediate- and high-risk prostate cancer: implications for focused radiotherapy. 
  • Evaluating the PCPT risk calculator in ten international biopsy cohorts: results from the Prostate Biopsy Collaborative Group. 
  • Evaluating the Prostate Cancer Prevention Trial High Grade Prostate Cancer Risk Calculator in 10 international biopsy cohorts: results from the Prostate Biopsy Collaborative Group. 
  • Evaluation of a contour-alignment technique for CT-guided prostate radiotherapy: an intra- and interobserver study. 
  • Evaluation of a novel precision template-guided biopsy system for detecting prostate cancer. 
  • Evidence for a novel hybrid immunotoxin recognizing ricin A-chain by one antigen-combining site and a prostate-restricted antigen by the remaining antigen-combining site: potential for immunotherapy. 
  • Exploring the Margin Recipe for Online Adaptive Radiation Therapy for Intermediate-Risk Prostate Cancer: An Intrafractional Seminal Vesicles Motion Analysis. 
  • Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression. 
  • Expression of androgen and estrogen related proteins in normal weight and obese prostate cancer patients. 
  • External validation of the SEARCH model for predicting aggressive recurrence after radical prostatectomy: results from the Duke Prostate Center Database. 
  • Extracellular iron diminishes anticancer effects of vitamin C: an in vitro study. 
  • Fatty acid synthase expression defines distinct molecular signatures in prostate cancer. 
  • Feasibility study of an intensity-modulated radiation model for the study of erectile dysfunction. 
  • Flow cytometric analysis of comedocarcinoma of the prostate: an uncommon histopathological variant of prostatic adenocarcinoma. 
  • Foamy gland adenocarcinoma of the prostate: incidence, Gleason grade, and early clinical outcome. 
  • Focal Therapy Eligibility Determined by Magnetic Resonance Imaging/Ultrasound Fusion Biopsy. 
  • Focal therapy for prostate cancer: pathologic basis. 
  • Focal therapy in prostate cancer-report from a consensus panel. 
  • Focal therapy of prostate and kidney cancer. 
  • Focal therapy of prostate cancer: making steady progress toward a first-line image-guided treatment modality. 
  • Focal therapy: patients, interventions, and outcomes--a report from a consensus meeting. 
  • Fraction of positive cores in prostate needle biopsy is significantly predictive of pathological stage in radical prostatectomy. 
  • GENIS: gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo. 
  • Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. 
  • Genetic factors influencing prostate cancer risk in Norwegian men. 
  • Geographic Differences in Baseline Prostate Inflammation and Relationship with Subsequent Prostate Cancer Risk: Results from the Multinational REDUCE Trial. 
  • Geometric and dosimetric evaluations of an online image-guidance strategy for 3D-CRT of prostate cancer. 
  • Germline mutations in HOXB13 and prostate-cancer risk. 
  • Germline mutations in PPFIBP2 are associated with lethal prostate cancer. 
  • Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis. 
  • Glutathione and glutathione S-transferase in benign and malignant prostate cell lines and prostate tissues. 
  • Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study. 
  • Gonadotropin-releasing hormone agonist overuse: urologists' response to reimbursement and characteristics associated with persistent overuse. 
  • Greater percent-free testosterone is associated with high-grade prostate cancer in men undergoing prostate biopsy. 
  • Health-related quality-of-life outcomes after anatomic retropubic radical prostatectomy in the phosphodiesterase type 5 ERA: impact of neurovascular bundle preservation. 
  • High-intensity focused ultrasound for prostate cancer: comparative definitions of biochemical failure. 
  • Histologic grade, DNA ploidy, and intraglandular tumor extent as indicators of tumor progression of clinical stage B prostatic carcinoma. A direct comparison. 
  • Human G(alpha q): cDNA and tissue distribution. 
  • Identification and characterization of proximal 6q deletions in prostate cancer. 
  • Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene. 
  • Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. 
  • Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate. 
  • Identifying Clinically Significant Prostate Cancers using 3-D In Vivo Acoustic Radiation Force Impulse Imaging with Whole-Mount Histology Validation. 
  • Immortalization of a human prostate stromal cell line using a recombinant retroviral approach. 
  • Immunoreactive prostatic specific antigen in male periurethral glands. 
  • Impact of nerve sparing on surgical margins and biochemical recurrence: results from the SEARCH database. 
  • Impact of primary Gleason grade on risk stratification for Gleason score 7 prostate cancers. 
  • Impact of prior local therapy on overall survival in men with metastatic castration-resistant prostate cancer: Results from Shared Equal Access Regional Cancer Hospital. 
  • Impact of socioeconomic status and race on clinical parameters of patients undergoing radical prostatectomy in an equal access health care system. 
  • Importance of prostate volume in the European Randomised Study of Screening for Prostate Cancer (ERSPC) risk calculators: results from the prostate biopsy collaborative group. 
  • Improved risk stratification for biochemical recurrence after radical prostatectomy using a novel risk group system based on prostate specific antigen density and biopsy Gleason score. 
  • In vitro cultivation of prostatic epithelium. 
  • In vitro culture of epithelial cells derived from urogenital tissues. 
  • In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms. 
  • Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+. 
  • Inferences about prostate intrafraction motion from pre- and posttreatment volumetric imaging. 
  • Influence of wide excision of the neurovascular bundle(s) on prognosis in men with clinically localized prostate cancer with established capsular penetration. 
  • Initial clinical assessment of CT-MRI image fusion software in localization of the prostate for 3D conformal radiation therapy. 
  • Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy. 
  • Insulin-like growth factor-1, insulin-like growth factor binding protein-3, and body mass index: clinical correlates of prostate volume among Black men. 
  • Interobserver variability leads to significant differences in quantifiers of prostate implant adequacy. 
  • Intratumoral inflammation is associated with more aggressive prostate cancer. 
  • Investigating 3D tumor distribution for optimized diagnosis of prostate cancer. 
  • Investigation of phosphoprotein signatures of archived prostate cancer tissue specimens via proteomic analysis. 
  • Invited commentary: Lower urinary tract symptoms and inflammation--weighing the evidence. 
  • Ion therapy of prostate cancer: daily rectal dose reduction by application of spacer gel. 
  • Isolation and characterization of a novel human prostatic stromal cell culture: DuK50. 
  • Lactoferrin gene expression is estrogen responsive in human and rhesus monkey endometrium. 
  • Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration. 
  • Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models. 
  • Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer. 
  • Loss of uteroglobin expression in prostate cancer: relationship to advancing grade. 
  • Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome. 
  • Magnetic Resonance Imaging Underestimation of Prostate Cancer Geometry: Use of Patient Specific Molds to Correlate Images with Whole Mount Pathology. 
  • Magnetic resonance spectroscopic studies of the prostate. 
  • Malakoplakia and carcinoma of the prostate. 
  • Massive locally extensive prostate cancer. 
  • Mechanism of Action of the Transobturator Sling for Post-Radical Prostatectomy Incontinence: A Multi-institutional Prospective Study Using Dynamic Magnetic Resonance Imaging. 
  • Medrogestone: a prospective study in the pharmaceutical management of benign prostatic hyperplasia. 
  • Metformin use and risk of prostate cancer: results from the REDUCE study. 
  • Monoclonal antibodies to different epitopes on a prostate tumor-associated antigen. Implications for immunotherapy. 
  • Monoclonal antibodies to tissue-associated antigens as antitumor reagents. 
  • Monoclonal antibodies to tissue-specific cell surface antigens. I. Characterization of an antibody to a prostate tissue antigen. 
  • Morphologic and immunologic studies of human prostatic carcinoma. 
  • Most Gleason 8 Biopsies are Downgraded at Prostatectomy-Does 4 + 4 = 7? 
  • Multi-institutional Evaluation of Elective Nodal Irradiation and/or Androgen Deprivation Therapy with Postprostatectomy Salvage Radiotherapy for Prostate Cancer. 
  • Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making. 
  • Multiple measures of carcinoma extent versus perineural invasion in prostate needle biopsy tissue in prediction of pathologic stage in a screening population. 
  • Multivariate analysis of race and adverse pathologic findings after radical prostatectomy. 
  • Nerve-sparing focal cryoablation of prostate cancer. 
  • New and Established Technology in Focal Ablation of the Prostate: A Systematic Review. 
  • New techniques in quantitative mass spectrometry. 
  • Normal prostate and adjacent structures: MR imaging at 1.5 T. 
  • Number and orientations of beams in intensity-modulated radiation treatments. 
  • Obese African-Americans with prostate cancer (T1c and a prostate-specific antigen, PSA, level of <10 ng/mL) have higher-risk pathological features and a greater risk of PSA recurrence than non-African-Americans. 
  • Obesity and oncological outcome after radical prostatectomy: impact of prostate-specific antigen-based prostate cancer screening: results from the Shared Equal Access Regional Cancer Hospital and Duke Prostate Center databases. 
  • Obesity and positive surgical margins by anatomic location after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital database. 
  • Obesity and prostate enlargement in men with localized prostate cancer. 
  • Obesity and risk of biochemical progression following radical prostatectomy at a tertiary care referral center. 
  • Obesity and survival after radical prostatectomy: A 10-year prospective cohort study. 
  • Obesity is associated with increased prostate growth and attenuated prostate volume reduction by dutasteride. 
  • Obesity, serum prostate specific antigen and prostate size: implications for prostate cancer detection. 
  • Observations of tissue response to acoustic radiation force: opportunities for imaging. 
  • Office treatment of male sexual dysfunction. 
  • Optimization of PSA screening policies: a comparison of the patient and societal perspectives. 
  • Optimized prostate biopsy via a statistical atlas of cancer spatial distribution. 
  • Optimizing monoscopic kV fluoro acquisition for prostate intrafraction motion evaluation. 
  • Optimizing performance and interpretation of prostate biopsy: a critical analysis of the literature. 
  • Orchiectomy and nilutamide or placebo as treatment of metastatic prostatic cancer in a multinational double-blind randomized trial. 
  • Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling. 
  • Outcome for repeated biopsy of the prostate: roles of serum PSA, small atypical glands, and prostatic intraepithelial neoplasia. 
  • Over half of contemporary clinical Gleason 8 on prostate biopsy are downgraded at radical prostatectomy. 
  • PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer. 
  • PDEF in prostate cancer. 
  • PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer. 
  • PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer. 
  • Pathological T2 sub-divisions as a prognostic factor in the biochemical recurrence of prostate cancer. 
  • Pathological upgrading at radical prostatectomy for patients with Grade Group 1 prostate cancer: implications of confirmatory testing for patients considering active surveillance. 
  • Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas. 
  • Pentosan polysulfate decreases prostate smooth muscle proliferation and extracellular matrix turnover. 
  • Percentage of tumor and tumor length in prostate biopsy specimens: a study of American veterans. 
  • Percentage of tumor in prostatectomy specimens: a study of American Veterans. 
  • Periprostatic Fat: A Risk Factor for Prostate Cancer? 
  • Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer. 
  • Pilot Study Evaluating a Rat Model of Radiation-induced Erectile Dysfunction Using an Image-guided Microirradiator. 
  • Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen. 
  • Platinum sensitivity in metastatic prostate cancer: does histology matter? 
  • Possible mechanism for seeding of tumor during radical prostatectomy. 
  • Postimplant analysis of transperineal interstitial permanent prostate brachytherapy: evidence for a learning curve in the first year at a single institution. 
  • Predicting biopsy-proven prostate cancer recurrence following cryosurgery. 
  • Predicting prostate biopsy results: The importance of PSA, age, and race. 
  • Predicting unilateral prostate cancer based on biopsy features: implications for focal ablative therapy--results from the SEARCH database. 
  • Predicting unilateral prostate cancer on routine diagnostic biopsy: sextant vs extended. 
  • Predictors of fluoroquinolone-resistant bacteria in the rectal vault of men undergoing prostate biopsy. 
  • Predictors of operative time during radical retropubic prostatectomy and robot-assisted laparoscopic prostatectomy. 
  • Predictors of prolonged operative time during robot-assisted laparoscopic radical prostatectomy. 
  • Preoperative PSA velocity and doubling time do not predict adverse pathologic features or biochemical recurrence after radical prostatectomy. 
  • Preoperative p27 status is an independent predictor of prostate specific antigen failure following radical prostatectomy. 
  • Preoperative predictors of blood loss at the time of radical prostatectomy: results from the SEARCH database. 
  • Preventing pain during office biopsy of the prostate: a single center, prospective, double-blind, 3-arm, parallel group, randomized clinical trial. 
  • Prevention of cautery burns during transurethral resection of prostate. 
  • Prognostic significance of DNA ploidy in carcinoma of prostate. 
  • Prognostic utility of the cell cycle progression score generated from biopsy in men treated with prostatectomy. 
  • Prohibitin mutations are uncommon in prostate cancer families linked to chromosome 17q. 
  • Prospective use of free PSA to avoid repeat prostate biopsies in men with elevated total PSA. 
  • Prostate Cancer Detection Rate of Freehand versus 3-Dimensional Template Mapping Biopsy Using a Magnetic Resonance Imaging-Ultrasound Fusion Device in Biopsy Naïve Men. 
  • Prostate Cancer Disseminated Tumor Cells are Rarely Detected in the Bone Marrow of Patients with Localized Disease Undergoing Radical Prostatectomy across Multiple Rare Cell Detection Platforms. 
  • Prostate Specific Antigen Density as a Predictor of Clinically Significant Prostate Cancer When the Prostate Specific Antigen is in the Diagnostic Gray Zone: Defining the Optimum Cutoff Point Stratified by Race and Body Mass Index. 
  • Prostate biopsies from black men express higher levels of aggressive disease biomarkers than prostate biopsies from white men. 
  • Prostate biopsy in selecting candidates for hemiablative focal therapy. 
  • Prostate biopsy protocols: 3D visualization-based evaluation and clinical correlation. 
  • Prostate cancer antigen 3 to select men for prostate biopsy: stop, go, or proceed with caution? 
  • Prostate cancer laterality as a rationale of focal ablative therapy for the treatment of clinically localized prostate cancer. 
  • Prostate cancer-specific mortality after radical prostatectomy or external beam radiation therapy in men with 1 or more high-risk factors. 
  • Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay. 
  • Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model. 
  • Prostate intrafraction motion assessed by simultaneous kV fluoroscopy at MV delivery II: adaptive strategies. 
  • Prostate intrafraction motion assessed by simultaneous kilovoltage fluoroscopy at megavoltage delivery I: clinical observations and pattern analysis. 
  • Prostate size and risk of high-grade, advanced prostate cancer and biochemical progression after radical prostatectomy: a search database study. 
  • Prostate specific antigen only progression of prostate cancer. 
  • Prostate weight and early potency in robot-assisted radical prostatectomy. 
  • Prostate. III--A structural feature characteristic of the rat prostate 5 alpha-reductase active site. 
  • Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism. 
  • Prostatic disorders: MR imaging at 1.5 T. 
  • Pseudohyperplastic prostatic adenocarcinoma. 
  • Quantification of prostate and seminal vesicle interfraction variation during IMRT. 
  • Quantitative expression profile of PSGR in prostate cancer. 
  • Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes. 
  • Race as an outcome predictor after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. 
  • Race does not predict the development of metastases in men with nonmetastatic castration-resistant prostate cancer. 
  • Racial differences in prognostic value of adult height for biochemical progression following radical prostatectomy. 
  • Radiation dose to the neurovascular bundles or penile bulb does not predict erectile dysfunction after prostate brachytherapy. 
  • Radiation-induced erectile dysfunction using prostate-confined modern radiotherapy in a rat model. 
  • Radical prostatectomy versus observation for localized prostate cancer. 
  • Radical retropubic prostatectomy: the influence of accessory pudendal arteries on the recovery of sexual function. 
  • Radioimmunoassay of prostatic acid phosphatase in carcinoma of the prostate. 
  • Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. 
  • Re-calibration and external validation of an existing nomogram to predict aggressive recurrences after radical prostatectomy. 
  • Reassessing the diagnostic yield of saturation biopsy of the prostate. 
  • Reduced Core Targeted (RCT) biopsy: Combining multiparametric magnetic resonance imaging - transrectal ultrasound fusion targeted biopsy with laterally-directed sextant biopsies - An alternative template for prostate fusion biopsy. 
  • Reduced prostate branching morphogenesis in stromal fibroblast, but not in epithelial, estrogen receptor α knockout mice. 
  • Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone. 
  • Relationship of serum sex-steroid hormones and prostate volume in African American men. 
  • Replicative epithelial cell cultures from normal human prostate gland. 
  • Report from Durham. 
  • Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. 
  • Residual disease after radical surgery or radiation therapy for prostate cancer. Clinical significance and therapeutic implications. 
  • Risk stratification for biochemical recurrence in men with positive surgical margins or extracapsular disease after radical prostatectomy: results from the SEARCH database. 
  • Robot-assisted laparoscopic prostatectomy is not associated with early postoperative radiation therapy. 
  • Role of oxidative stress in a rat model of radiation-induced erectile dysfunction. 
  • Role of transrectal ultrasonography (TRUS) in focal therapy of prostate cancer: report from a Consensus Panel. 
  • Scanning and transmission electron microscopy of human prostatic acinar cells. 
  • Scanning electron microscopy of hyperplastic and neoplastic human prostate. 
  • Screening for prostate cancer in high risk populations. 
  • Serum prostate-specific antigen (PSA) concentration is positively associated with rate of disease reclassification on subsequent active surveillance prostate biopsy in men with low PSA density. 
  • Short-term functional outcomes and complications associated with transperineal template prostate mapping biopsy. 
  • Should a positive surgical margin following radical prostatectomy be pathological stage T2 or T3? Results from the SEARCH database. 
  • Similarities between static and rotational intensity-modulated plans. 
  • Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival. 
  • Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging. 
  • Smoking is a predictor of adverse pathological features at radical prostatectomy: Results from the Shared Equal Access Regional Cancer Hospital database. 
  • Somatic innervation of the feline lower urinary tract. 
  • Staging evaluation for patients with adenocarcinoma of the prostate. American College of Radiology. ACR Appropriateness Criteria. 
  • Statin Use, Serum Lipids, and Prostate Inflammation in Men with a Negative Prostate Biopsy: Results from the REDUCE Trial. 
  • Stratification of pathologic features in radical prostatectomy specimens that are predictive of elevated initial postoperative serum prostate-specific antigen levels. 
  • Structured reporting of prostate magnetic resonance imaging has the potential to improve interdisciplinary communication. 
  • Symptom and function profiles of men with localized prostate cancer. 
  • Systematic biopsies: do they add prognostic information in men with clinically localized prostate cancer treated with radiation therapy alone? 
  • Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. 
  • TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. 
  • Targeted prostate biopsies: the complexity behind a simple concept. 
  • Targeted prostate biopsy using statistical image analysis. 
  • Temporal relationships of statin and terminin expression in ventral lobe of rat prostate following castration. 
  • Temporally controlled prostate epithelium-specific gene alterations. 
  • Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy. 
  • The Association between Phosphodiesterase Type 5 Inhibitors and Prostate Cancer: Results from the REDUCE Study. 
  • The Calculus of Serum PSA. 
  • The Shared Equal Access Regional Cancer Hospital (SEARCH) nomogram for risk stratification in intermediate risk group of men with prostate cancer: validation in the Duke Prostate Center database. 
  • The alpha 1C-adrenoceptor in human prostate: cloning, functional expression, and localization to specific prostatic cell types. 
  • The association between prostate size and Gleason score upgrading depends on the number of biopsy cores obtained: results from the Shared Equal Access Regional Cancer Hospital Database. 
  • The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression. 
  • The contemporary value of pretreatment prostatic acid phosphatase to predict pathological stage and recurrence in radical prostatectomy cases. 
  • The effect of race on the discriminatory accuracy of models to predict biochemical recurrence after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital and Duke Prostate Center databases. 
  • The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo. 
  • The impact of obesity on the predictive accuracy of PSA in men undergoing prostate biopsy. 
  • The incidence of fluoroquinolone resistant infections after prostate biopsy--are fluoroquinolones still effective prophylaxis? 
  • The interplay between obesity and the accuracy of prostate-specific antigen (PSA) for predicting prostate cancer. 
  • The optimisation of wedge filters in radiotherapy of the prostate. 
  • The ratio of prostate chips with cancer: a new measure of tumor extent and its relationship to grade and prognosis. 
  • The relationship between prostate-specific antigen and prostate cancer risk: the Prostate Biopsy Collaborative Group. 
  • The role of Alzheimer's disease-related presenilin 1 in intercellular adhesion. 
  • The role of androgen deprivation therapy combined with prostate brachytherapy. 
  • The role of seminal vesicle motion in target margin assessment for online image-guided radiotherapy for prostate cancer. 
  • The role of transrectal saturation biopsy in tumour localization: pathological correlation after retropubic radical prostatectomy and implication for focal ablative therapy. 
  • The state of prostate MRI in 2013. 
  • Three-dimensional localization and targeting of prostate cancer foci with imaging and histopathologic correlation: establishing a multidisciplinary team for quality improvement. 
  • Thresholds for PSA doubling time in men with non-metastatic castration-resistant prostate cancer. 
  • Thresholds for thermal damage to normal tissues: an update. 
  • Time trends in biochemical recurrence after radical prostatectomy: results of the SEARCH database. 
  • Transrectal gene therapy of the prostate in the canine model. 
  • Tumor percent involvement predicts prostate specific antigen recurrence after radical prostatectomy only in men with smaller prostate. 
  • Tumor volume, tumor percentage involvement, or prostate volume: which is predictive of prostate-specific antigen recurrence? 
  • Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer. 
  • Tyrol Prostate Cancer Demonstration Project: early detection, treatment, outcome, incidence and mortality. 
  • Update on transrectal ultrasound-guided needle biopsy of the prostate. 
  • Urinary outcomes are significantly affected by nerve sparing quality during radical prostatectomy. 
  • Urine chemokines indicate pathogenic association of obesity with BPH/LUTS. 
  • Use of 111in-capromab pendetide immunoscintigraphy to image localized prostate cancer foci within the prostate gland. 
  • Use of serum creatinine to predict pathologic stage and recurrence among radical prostatectomy patients. 
  • Using the percentage of biopsy cores positive for cancer, pretreatment PSA, and highest biopsy Gleason sum to predict pathologic stage after radical prostatectomy: the Center for Prostate Disease Research nomograms. 
  • Validation of histone deacetylase 3 as a therapeutic target in castration-resistant prostate cancer. 
  • Validation of the 2015 prostate cancer grade groups for predicting long-term oncologic outcomes in a shared equal-access health system. 
  • Variables in predicting survival based on treating "PSA-only" relapse. 
  • Variations of focal regions versus numbers and positions of sources in two-dimensional media. 
  • Words of wisdom. Re: Low serum neutrophil count predicts a positive prostate biopsy. 
  • alpha1-adrenergic receptors in the lower urinary tract and vascular bed: potential role for the alpha1d subtype in filling symptoms and effects of ageing on vascular expression. 
  • mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. 
• 

  Keywords of People

  • Bitting, Rhonda L, Instructor in the Department of Medicine, Medicine, Medical Oncology
  • Inman, Brant Allen, Cary N. Robertson, MD, Associate Professor, Surgery, Urology
  • Koontz, Bridget Fey, Associate Professor of Radiation Oncology, Radiation Oncology
  • Nightingale, Kathryn Radabaugh, Theo Pilkington Distinguished Professor of Biomedical Engineering, Biomedical Engineering
  • O'Daniel, Jennifer Colleen, Assistant Professor of Radiation Oncology, Radiation Oncology
  • Routh, Jonathan Charles, Paul H. Sherman, M.D. Distinguished Associate Professor of Surgery, Pediatrics
  • Roy Choudhury, Kingshuk, Adjunct Associate Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics