Proteinuria

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  Subject Areas on Research

  • A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. 
  • A novel mouse model of podocyte depletion. 
  • A proposed taxonomy for the podocytopathies: a reassessment of the primary nephrotic diseases. 
  • A randomized trial of a 6-week course of celecoxib on proteinuria in diabetic kidney disease. 
  • Abnormal iron deposition in renal cells in the rat with chronic angiotensin II administration. 
  • Absence of biochemical evidence for renal and hepatic dysfunction after 8 hours of 1.25 minimum alveolar concentration sevoflurane anesthesia in volunteers. 
  • Agalsidase-beta therapy for advanced Fabry disease: a randomized trial. 
  • Altered T-dependent antigen responses and development of autoimmune symptoms in mice lacking E2A in T lymphocytes. 
  • Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data. 
  • Anti-angiogenic therapy for high-grade glioma. 
  • Antiangiogenic therapy for high-grade glioma. 
  • Antifibrinolytic use during cardiac and hepatic surgery makes tubular proteinuria-based early biomarkers poor tools to diagnose perioperative acute kidney injury. 
  • Assessment of renal function during pregnancy using a random urine protein to creatinine ratio and Cockcroft-Gault formula. 
  • Association between proteinuria and incident colorectal cancer: analysis of a nationwide population-based database. 
  • Association of high pulse pressure with proteinuria in subjects with diabetes, prediabetes, or normal glucose tolerance in a large Japanese general population sample. 
  • Association of postoperative proteinuria with AKI after cardiac surgery among patients at high risk. 
  • Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study. 
  • Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022). 
  • Bevacizumab in the treatment of metastatic colorectal cancer: safety profile and management of adverse events. 
  • Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients. 
  • Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis. 
  • Changes in proteinuria and albuminuria with initiation of antiretroviral therapy: data from a randomized trial comparing tenofovir disoproxil fumarate/emtricitabine versus abacavir/lamivudine. 
  • Chronic kidney disease in HIV infection: an urban epidemic. 
  • Clinical trials treating focal segmental glomerulosclerosis should measure patient quality of life. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study. 
  • Complete Remission in the Nephrotic Syndrome Study Network. 
  • Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease. 
  • Control of blood pressure in chronic kidney disease: how low to go? 
  • Cost-effectiveness of screening for proteinuria. 
  • Definition of proteinuria among women with HIV infection. 
  • Differential risk of hypertensive disorders of pregnancy among Hispanic women. 
  • Direct, progressive association of cardiovascular risk factors with incident proteinuria: results from the Korea Medical Insurance Corporation (KMIC) study. 
  • Disease activity, proteinuria, and vitamin D status in children with systemic lupus erythematosus and juvenile dermatomyositis. 
  • Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. 
  • Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial. 
  • Ethnic differences and determinants of proteinuria among South Asian subgroups in Pakistan. 
  • Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation. 
  • Factors Associated with Chronic Kidney Disease and Their Clinical Utility in Primary Care Clinics in a Multi-Ethnic Southeast Asian Population. 
  • Final conclusions and recommendations of the National Lipid Association Statin Safety Assessment Task Force. 
  • Focal segmental glomerulosclerosis associated with nephrotic syndrome in cholesterol atheroembolism: clinicopathological correlations. 
  • From man to fish: What can Zebrafish tell us about ApoL1 nephropathy? 
  • Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology. 
  • Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension. 
  • Glycohemoglobin not as predictive as fasting glucose as a measure of prediabetes in predicting proteinuria. 
  • HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection. 
  • HIV-associated nephropathy: a case study in race and genetics. 
  • Heart disease epidemic in Pakistan: women and men at equal risk. 
  • Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection. 
  • Host APOL1 genotype is independently associated with proteinuria in HIV infection. 
  • IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage. 
  • Idiopathic collapsing focal segmental glomerulosclerosis: a clinicopathologic study. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies. 
  • Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1. 
  • Kidney disease other than renal crisis in patients with diffuse scleroderma. 
  • Kidney lesions in Rocky Mountain spotted fever: a light-, immunofluorescence-, and electron-microscopic study. 
  • Lithium-induced nephrotic syndrome. 
  • Long-acting natriuretic peptide, vessel dilator, and kaliuretic peptide enhance urinary excretion rate of albumin, total protein, and beta(2)-microglobulin in patients with congestive heart failure. 
  • Long-term effect of uninephrectomy on serum creatinine concentration and arterial blood pressure. 
  • Long-term outcome of early steroid withdrawal after kidney transplantation in African American recipients monitored by surveillance biopsy. 
  • Low-flow sevoflurane compared with low-flow isoflurane anesthesia in patients with stable renal insufficiency. 
  • Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells. 
  • Management of glomerular proteinuria: a commentary. 
  • Microalbuminuria predicts overt proteinuria among patients with HIV infection. 
  • Modulation of podocyte phenotype in collapsing glomerulopathies. 
  • Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations. 
  • Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo. 
  • Net endogenous acid production is associated with a faster decline in GFR in African Americans. 
  • Oligoclonal banding detected by urinary protein electrophoresis and immunofixation in two patients with the acquired immune deficiency syndrome and proteinuria. 
  • Patient awareness of chronic kidney disease: trends and predictors. 
  • Podocyte effacement closely links to suPAR levels at time of posttransplantation focal segmental glomerulosclerosis occurrence and improves with therapy. 
  • Population-based screening for CKD. 
  • Pre-existing albuminuria predicts AIDS and non-AIDS mortality in women initiating antiretroviral therapy. 
  • Pre-operative proteinuria in left ventricular assist devices and clinical outcome. 
  • Predictors of preterm birth in patients with mild systemic lupus erythematosus. 
  • Predictors of proteinuria and renal failure among women with HIV infection. 
  • Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus. 
  • Prevalence and clinical correlates of glomerulopathy in children with sickle cell disease. 
  • Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study. 
  • Prevalence and predictors of proteinuria in HIV-infected and uninfected pregnant women in Cameroon. 
  • Preventing renal dysfunction in patients with hypertension: clinical implications from the early AASK Trial results. 
  • Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. 
  • Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease. 
  • Proteinuria as a modifiable risk factor for the progression of non-diabetic renal disease. 
  • Proteinuria in South Asian children: prevalence and determinants. 
  • Proteinuria in pediatric renal transplant recipients during the first 60 post-transplant days. 
  • Pulmonary hypertension associated with sickle cell disease: clinical and laboratory endpoints and disease outcomes. 
  • Quantification of Glomerular Structural Lesions: Associations With Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome. 
  • Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis. 
  • Renal disease in type I glycogen storage disease. 
  • Renal pathology patterns in type II diabetes mellitus: relationship with retinopathy. The Collaborative Study Group. 
  • Renal transplantation between HL-A identical donor-recipient pairs. Functional and morphological evaluation. 
  • Renin-angiotensin system inhibition in advanced chronic kidney disease: how low can the kidney function go? 
  • Retinal vascular abnormalities in persons with type 1 diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVIII. 
  • Revisiting the determinants of the glomerular filtration barrier: what goes round must come round. 
  • Risk factors for reduced glomerular filtration rate in a Nicaraguan community affected by Mesoamerican nephropathy. 
  • Risk for Proteinuria in Newly Defined Hypertensive People Based on the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline. 
  • Role of urine and serum protein electrophoresis in evaluation of nephrotic-range proteinuria. 
  • S-Nitrosoglutathione protects the spinal bladder: novel therapeutic approach to post-spinal cord injury bladder remodeling. 
  • Safety of bevacizumab in patients with metastatic breast cancer. 
  • Safety of low-flow sevoflurane anesthesia in patients with chronically impaired renal function is not proven. 
  • Screening for proteinuria in US adults: a cost-effectiveness analysis. 
  • Steroid hormone regulation of specific gene expression. 
  • TRPC Channels in Proteinuric Kidney Diseases. 
  • Targeted deletion of angiotensin II type 1A receptor does not protect mice from progressive nephropathy of overload proteinuria. 
  • The EP4 receptor for prostaglandin E2 in glomerular disease: a good receptor turned bad? 
  • The Utility of Urinalysis in Determining the Risk of Renal Relapse in ANCA-Associated Vasculitis. 
  • The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. 
  • The effect of angiotensin-converting-enzyme inhibitors on progression of advanced polycystic kidney disease. 
  • The effects of cytotoxic therapy in progressive IgA nephropathy. 
  • The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group. 
  • The impact of disease duration on quality of life in children with nephrotic syndrome: a Midwest Pediatric Nephrology Consortium study. 
  • The impact of hepatitis C virus coinfection on HIV-related kidney disease: a systematic review and meta-analysis. 
  • The impact of temperature and urinary constituents on urine viscosity and its relevance to bladder hyperthermia treatment. 
  • The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension. 
  • The use of D-penicillamine in cystinuria: efficacy and untoward reactions. 
  • Therapeutic targets in focal and segmental glomerulosclerosis. 
  • Time-Updated Changes in Estimated GFR and Proteinuria and Major Adverse Cardiac Events: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. 
  • Treatment outcome of late steroid-resistant nephrotic syndrome: a study by the Midwest Pediatric Nephrology Consortium. 
  • Tubular markers are associated with decline in kidney function in proteinuric type 2 diabetic patients. 
  • Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration. 
  • Ultrastructural Characterization of Proteinuric Patients Predicts Clinical Outcomes. 
  • Urinalysis findings and urinary kidney injury biomarker concentrations. 
  • Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice. 
  • VEGF inhibition and renal thrombotic microangiopathy. 
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  Keywords of People

  • Middleton, John Paul, Professor of Medicine, Medicine, Nephrology
  • Schanberg, Laura Eve, Professor of Pediatrics, Pediatrics, Rheumatology