Pruritus

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  Subject Areas on Research

  • A cellular mechanism for age-induced itch. 
  • A child's experience of itch: the first step towards patient-centred measures. 
  • A daily skincare regimen with a unique ceramide and filaggrin formulation rapidly improves chronic xerosis, pruritus, and quality of life in older adults. 
  • A monoclonal antibody that targets a NaV1.7 channel voltage sensor for pain and itch relief. 
  • A pilot quality-of-life instrument for pruritus. 
  • A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men. 
  • A structurally optimized FXR agonist, MET409, reduced liver fat content over 12 weeks in patients with non-alcoholic steatohepatitis. 
  • Acquired peanut hypersensitivity after transfusion. 
  • Aprepitant for the Treatment of Chronic Refractory Pruritus. 
  • Assessment of Quality of Life in Chronic Pruritus: Relationship Between ItchyQoL and Dermatological Life Quality Index in 1,150 Patients. 
  • Astrocytes in chronic pain and itch. 
  • Beta-lactam antibiotic-induced pseudoporphyria. 
  • Bird-mite infestation in a university hospital. 
  • Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition. 
  • Chronic Pruritus Severity and QoL Impact on Healthcare Utilization among Veterans: A National Survey. 
  • Chronic pruritus in HIV-positive patients in the southeastern United States: its prevalence and effect on quality of life. 
  • Circulating blood eosinophils as a biomarker for variable clinical presentation and therapeutic response in patients with chronic pruritus of unknown origin. 
  • Clinically meaningful reduction in pruritus in patients with cutaneous T-cell lymphoma treated with romidepsin. 
  • Cluster Analysis of Circulating Plasma Biomarkers in Prurigo Nodularis Reveals a Distinct Systemic Inflammatory Signature in African Americans. 
  • Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch. 
  • Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch. 
  • Cross-European validation of the ItchyQoL in pruritic dermatoses. 
  • Determination of the effective therapeutic dose of intrathecal sufentanil for extracorporeal shock wave lithotripsy. 
  • Dexamethasone for the prophylaxis of postoperative nausea and vomiting associated with neuraxial morphine administration: a systematic review and meta-analysis. 
  • Effects of neuroimmune axis modulation by aprepitant on antipruritic and global disease severity in patients with cutaneous T-cell lymphoma. 
  • Emerging Role of Transient Receptor Potential Vanilloid 4 (TRPV4) Ion Channel in Acute and Chronic Itch. 
  • Emerging role of Toll-like receptors in the control of pain and itch. 
  • Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine. 
  • Evaluation of the Performance of a Nature-Based Sensitive Skin Regimen in Subjects With Clinically Diagnosed Sensitive Skin. 
  • Factor analysis of subjective descriptors of chronic pruritus and association with quality of life: A cross-sectional survey. 
  • Factors mediating the impact of chronic pruritus on quality of life. 
  • Forearm neuropathy and pruritus. 
  • German version of ItchyQoL: validation and initial clinical findings. 
  • IL-31 Inhibition as a Therapeutic Approach for the Management of Chronic Pruritic Dermatoses. 
  • Iliohypogastric-ilioinguinal peripheral nerve block for post-Cesarean delivery analgesia decreases morphine use but not opioid-related side effects. 
  • Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse. 
  • Inhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch. 
  • Intense pruritus and failure to thrive in Alagille syndrome. 
  • Intrahepatic Cholestasis of Pregnancy: A Review of Diagnosis and Management. 
  • Involvement of Sensory Neurone-TRPV4 in Acute and Chronic Itch Behaviours. 
  • Itch control by Toll-like receptors. 
  • ItchyQoL bands: pilot clinical interpretation of scores. 
  • Linear, pruritic red to brown papules on the left chest. 
  • Localized pruritus-notalgia paresthetica. 
  • Management of Menopausal Symptoms for Women Who Are at High Risk of Thrombosis. 
  • Monitoring, prevention and treatment of side effects of long-acting neuraxial opioids for post-cesarean analgesia. 
  • Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? 
  • New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms? 
  • Oral transmucosal fentanyl citrate as an anaesthetic premedication when dosed to an opioid effect vs total opioid consumption. 
  • Outbreak of psychosomatic illness at a rural elementary school. 
  • Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice. 
  • Pain and itch outcome trajectories differ among European American and African American survivors of major thermal burn injury. 
  • Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch. 
  • Periumbilical contact dermatitis. 
  • Pilot study of the use of naltrexone to treat the severe pruritus of cholestatic liver disease. 
  • Poststroke pruritus. 
  • Primary biliary cirrhosis: new therapeutic directions. 
  • Prophylaxis and treatment of the side-effects of neuraxial morphine analgesia following cesarean delivery. 
  • Pruritic urticarial papules and plaques of pregnancy presenting in the postpartum period: a case report. 
  • Pruritic urticarial papules and plaques of pregnancy. Clinical experience in twenty-five patients. 
  • Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant. 
  • Pruritus epidemiology and quality of life. 
  • Pruritus in patients with solid tumors: an overlooked supportive care need. 
  • Pruritus in systemic disease: mechanisms and management. 
  • Pruritus. 
  • Racial disparities in the impact of chronic pruritus: A cross-sectional study on quality of life and resource utilization in United States veterans. 
  • Radiation Dermatitis: A Prevention Protocol for Patients With Breast Cancer. 
  • Recent Progress in Understanding the Mechanisms of Pain and Itch: the Second Special Issue. 
  • Recent progress in understanding the mechanisms of pain and itch. 
  • Regulation of Pain and Itch by TRP Channels. 
  • Rituximab monotherapy to treat intravascular large B-cell lymphoma manifesting as pruritic calf patch in an elderly female. 
  • Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty. 
  • Scratching after Stroking and Poking: A Spinal Circuit Underlying Mechanical Itch. 
  • Scratching the itch: a new therapeutic target for dialysis-associated pruritus? 
  • Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea, and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis. 
  • Sertraline as a first-line treatment for cholestatic pruritus. 
  • Sleep disturbance in adults with chronic pruritic dermatoses is associated with increased C-reactive protein levels. 
  • Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel. 
  • Structure, function and pharmacology of human itch GPCRs. 
  • Symptoms of depression and anxiety are associated with poorer functional outcomes in chronic pruritus. 
  • TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. 
  • TNF-α/TNFR1 Signaling is Required for the Full Expression of Acute and Chronic Itch in Mice via Peripheral and Central Mechanisms. 
  • The Annual Direct and Indirect Health Care Costs for Patients with Chronic Pruritus and their Determining Factors. 
  • The histopathology of Phthirus pubis. 
  • The impact of pruritus on quality of life: the skin equivalent of pain. 
  • The modified Patient and Observer Scar Assessment Scale: a novel approach to defining pathologic and nonpathologic scarring. 
  • The return of the common bedbug. 
  • The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes. 
  • Third Special Issue on Mechanisms of Pain and Itch. 
  • Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice. 
  • Toll-like receptor 7 mediates pruritus. 
  • Tools to study the severity of itch in 8- to 17-year-old children: Validation of TweenItchyQoL and ItchyQuant. 
  • Transcriptome profiling reveals Th2 bias and identifies endogenous itch mediators in poison ivy contact dermatitis. 
  • Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch. 
  • Unilateral neurogenic pruritus following stroke. 
  • Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study. 
  • VGLUT2-dependent glutamate release from nociceptors is required to sense pain and suppress itch. 
  • Validation and Banding of the ItchyQuant: A Self-Report Itch Severity Scale. 
  • What causes hidradenitis suppurativa ?-15 years after. 
  • miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus.