Pseudomonas aeruginosa

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  Subject Areas on Research

  • A 9-Year retrospective review of antibiotic cycling in a surgical intensive care unit. 
  • A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens. 
  • Ability of an antibiogram to predict Pseudomonas aeruginosa susceptibility to targeted antimicrobials based on hospital day of isolation. 
  • Accurate Quantum Mechanical/Molecular Mechanical Calculations of Reduction Potentials in Azurin Variants. 
  • Acute renal failure in cystic fibrosis: association with inhaled tobramycin therapy. 
  • Adaptive Responses of Pseudomonas aeruginosa to Treatment with Antibiotics. 
  • Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells. 
  • Age of Pseudomonas aeruginosa acquisition and subsequent severity of cystic fibrosis lung disease. 
  • Analysis of two- and three-year trends in antimicrobial resistance in intensive care units using unit-specific antibiograms. 
  • AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide. 
  • Antibiotic eluting chitosan glycerophosphate implant in the setting of acute bacterial sinusitis: a rabbit model. 
  • Antibiotic susceptibility testing of Pseudomonas aeruginosa: selection of a control strain and criteria for magnesium and calcium content in media. 
  • Antioxidant enzyme expression in clinical isolates of Pseudomonas aeruginosa: identification of an atypical form of manganese superoxide dismutase. 
  • Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia. 
  • Approach to eradication of initial Pseudomonas aeruginosa infection in children with cystic fibrosis. 
  • Aquatic biofouling prevention by electrically charged nanocomposite polymer thin film membranes. 
  • Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis. 
  • Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry. 
  • Bacterial colonization of intravenous catheter materials in vitro and in vivo. 
  • Bacterial endocarditis in a child with a Broviac catheter. 
  • Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study. 
  • Bacterial penetration of the mucosal barrier by targeting lipid rafts. 
  • Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study. 
  • Bringing cells to the edge. 
  • Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients. 
  • Chaperone-assisted assembly and molecular architecture of adhesive pili. 
  • Characterizing reactive oxygen generation and bacterial inactivation by a zerovalent iron-fullerene nano-composite device at neutral pH under UV-A illumination. 
  • Collective colony growth is optimized by branching pattern formation in Pseudomonas aeruginosa. 
  • Cometabolism of cis-1,2-dichloroethene by aerobic cultures grown on vinyl chloride as the primary substrate. 
  • Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis. 
  • Comparative evaluation of the microbicidal activity of low-temperature sterilization technologies to steam sterilization. 
  • Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa. 
  • Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. 
  • Cutaneous Burn Injury Modulates Urinary Antimicrobial Peptide Responses and the Urinary Microbiome. 
  • Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones. 
  • Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs. 
  • Demystifying "bad luck": Seemingly unrelated risk factors for CLAD may be connected by a common pathway. 
  • Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. 
  • Development of resistance in Pseudomonas aeruginosa to imipenem, norfloxacin, and ciprofloxacin during therapy: proof provided by typing with a DNA probe. 
  • Disinfectant testing using a modified use-dilution method: collaborative study. 
  • Distribution of serotypes and antibiotic resistance of invasive Pseudomonas aeruginosa in a multi-country collection. 
  • Does the F508-CFTR mutation induce a proinflammatory response in human airway epithelial cells? 
  • Drug design from the cryptic inhibitor envelope. 
  • Dual action antimicrobials: nitric oxide release from quaternary ammonium-functionalized silica nanoparticles. 
  • Early anti-pseudomonal acquisition in young patients with cystic fibrosis: rationale and design of the EPIC clinical trial and observational study'. 
  • Efficacy of anti-pseudomonal antibiotics: need to reconsider the empirical use of cefepime. 
  • Efficacy of common antiseptic solutions against clinically relevant microorganisms in biofilm. 
  • Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India. 
  • Endosymbiosis: the evil within. 
  • Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage. 
  • Exploring biological electron transfer pathway dynamics with the Pathways plugin for VMD. 
  • Fatal respiratory infection due to ST308 VIM-1-producing Pseudomonas aeruginosa in a lung transplant recipient: case report and review of the literature. 
  • Genetic Screen Reveals Link between the Maternal Effect Sterile Gene mes-1 and Pseudomonas aeruginosa-induced Neurodegeneration in Caenorhabditis elegans. 
  • Global epidemiology and clinical outcomes of carbapenem-resistant Pseudomonas aeruginosa and associated carbapenemases (POP): a prospective cohort study. 
  • Gram-negative bacteremia upon hospital admission: when should Pseudomonas aeruginosa be suspected? 
  • Growth inhibition of pathogenic bacteria by sulfonylurea herbicides. 
  • High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors. 
  • Identification of Metabolic Changes in Ileum, Jejunum, Skeletal Muscle, Liver, and Lung in a Continuous I.V. Pseudomonas aeruginosa Model of Sepsis Using Nontargeted Metabolomics Analysis. 
  • Identification of a molybdopterin-containing molybdenum cofactor in xanthine dehydrogenase from Pseudomonas aeruginosa. 
  • Immunohistologic quantification of Pseudomonas aeruginosa in the tracheobronchial tree from patients with cystic fibrosis. 
  • Improved antitumor activity of a recombinant anti-Lewis(y) immunotoxin not requiring proteolytic activation. 
  • In vivo imaging and genetic analysis link bacterial motility and symbiosis in the zebrafish gut. 
  • Influence of scaffold size on bactericidal activity of nitric oxide-releasing silica nanoparticles. 
  • Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis. 
  • Interpretive criteria and quality control for antimicrobial susceptibility tests of levofloxacin. 
  • Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective. 
  • Intravascular coagulation--a source of possible error in carbon-clearance determinations. 
  • Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. 
  • Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates inflammatory response and homeostasis of spleen and colon in experimental model of Pseudomonas aeruginosa pneumonia. 
  • Low-Avidity Autoantibodies against Bactericidal/Permeability-Increasing Protein Occur in Gram-Negative and Gram-Positive Bacteremia. 
  • Lung transplantation for Williams-Campbell syndrome. 
  • MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa. 
  • Malignant otitis externa (MOE) causing cerebral abscess and facial nerve palsy. 
  • Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract. 
  • Mild Traumatic Brain Injury in Mice Beneficially Alters Lung NK1R and Structural Protein Expression to Enhance Survival after Pseudomonas aeruginosa Infection. 
  • Minimum inhibitory and bactericidal concentrations of 44 antimicrobial agents against three standard control strains in broth with and without human serum. 
  • Naturally produced outer membrane vesicles from Pseudomonas aeruginosa elicit a potent innate immune response via combined sensing of both lipopolysaccharide and protein components. 
  • Neutrophils self-limit swarming to contain bacterial growth in vivo. 
  • New source of Pseudomonas aeruginosa in a nursery. 
  • Ofloxacin, a new broad-spectrum fluoroquinolone. Results from a Multicenter, National Comparative Activity Surveillance Study. The Ofloxacin Surveillance Group. 
  • Outer Membrane Vesicles Displaying a Heterologous PcrV-HitA Fusion Antigen Promote Protection against Pulmonary Pseudomonas aeruginosa Infection. 
  • Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein. 
  • Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance. 
  • Phosphate-containing polyethylene glycol polymers prevent lethal sepsis by multidrug-resistant pathogens. 
  • Polycationic Nanofibers for Nucleic Acid Scavenging. 
  • Povidone-iodine to prevent ophthalmia neonatorum. 
  • Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. 
  • Protease cleavage of iron-transferrin augments pyocyanin-mediated endothelial cell injury via promotion of hydroxyl radical formation. 
  • Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation. 
  • Pseudomonas aeruginosa Bacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide. 
  • Pseudomonas aeruginosa Leucine Aminopeptidase Influences Early Biofilm Composition and Structure via Vesicle-Associated Antibiofilm Activity. 
  • Pseudomonas aeruginosa activates caspase 1 through Ipaf. 
  • Pseudomonas aeruginosa elastase degrades surfactant proteins A and D. 
  • Pseudomonas aeruginosa serology and risk for re-isolation in the EPIC trial. 
  • Pseudomonas colonization in cystic fibrosis. A study of 160 patients. 
  • Pseudomonas exotoxin A mutants. Replacement of surface exposed residues in domain II with cysteine residues that can be modified with polyethylene glycol in a site-specific manner. 
  • Purification of outer membrane vesicles from Pseudomonas aeruginosa and their activation of an IL-8 response. 
  • Quality control limits for ampicillin, carbenicillin, mezlocillin, and piperacillin disk diffusion susceptibility tests: a collaborative study. 
  • Quicker determination of antibiotic susceptibility in urinary tract infections. 
  • Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa. 
  • Rapid Antimicrobial Susceptibility Testing Using Forward Laser Light Scatter Technology. 
  • Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam Against Pseudomonas aeruginosa: PRIMERS IV. 
  • Recalcitrant rhinosinusitis, innate immunity, and mannose-binding lectin. 
  • Recombinant Pseudomonas Bionanoparticles Induce Protection against Pneumonic Pseudomonas aeruginosa Infection. 
  • Reducing Environmental Toxicity of Silver Nanoparticles through Shape Control. 
  • Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity. 
  • Results from a 13-Year Prospective Cohort Study Show Increased Mortality Associated with Bloodstream Infections Caused by Pseudomonas aeruginosa Compared to Other Bacteria. 
  • Revision of standards for adjusting the cation content of Mueller-Hinton broth for testing susceptibility of Pseudomonas aeruginosa to aminoglycosides. 
  • Rhythmic bacterial susceptibility to antibiotics at a large hospital. 
  • Risk factors associated with unfavorable short-term treatment outcome in patients with documented Pseudomonas aeruginosa infection. 
  • Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. 
  • Role of size and shape on biofilm eradication for nitric oxide-releasing silica nanoparticles. 
  • Rotenone Modulates Caenorhabditis elegans Immunometabolism and Pathogen Susceptibility. 
  • Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies. 
  • Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial. 
  • Serum dilution test for bactericidal activity. I. Selection of a physiologic diluent. 
  • Serum dilution test for bactericidal activity. II. Standardization and correlation with antimicrobial assays and susceptibility tests. 
  • Serum vascular endothelial growth factor is elevated in cystic fibrosis and decreases with treatment of acute pulmonary exacerbation. 
  • Specific incorporation of molybdopterin in xanthine dehydrogenase of Pseudomonas aeruginosa. 
  • Standard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis. 
  • Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa. 
  • SulA inhibits assembly of FtsZ by a simple sequestration mechanism. 
  • Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study. 
  • The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa. 
  • The biological activity of a liposomal complete core lipopolysaccharide vaccine. 
  • The cell division protein MinD from Pseudomonas aeruginosa dominates the assembly of the MinC-MinD copolymers. 
  • Transcription-associated mutation of lasR in Pseudomonas aeruginosa. 
  • Transport and retention of selected engineered nanoparticles by porous media in the presence of a biofilm. 
  • United States geographic bacteria susceptibility patterns. 1996 ASCP Susceptibility Testing Group. American Society of Clinical Pathologists. 
  • Universal antibiotic tolerance arising from antibiotic-triggered accumulation of pyocyanin in Pseudomonas aeruginosa. 
  • Vestibulotoxicity in a patient without renal failure after inhaled tobramycin. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Kuehn, Margarethe Joanna, Associate Professor of Biochemistry, Cell Biology