Pterins

• 

  Subject Areas on Research

  • 31P-NMR of free and protein-bound molybdopterin guanine dinucleotide. 
  • Association of molybdopterin guanine dinucleotide with Escherichia coli dimethyl sulfoxide reductase: effect of tungstate and a mob mutation. 
  • Chemistry and biology of the molybdenum cofactors. 
  • Folate fortification of rice by metabolic engineering. 
  • Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules. 
  • How an enzyme binds the C1 carrier tetrahydromethanopterin. Structure of the tetrahydromethanopterin-dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1. 
  • Human molybdenum cofactor deficiency. 
  • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. 
  • Identification of molybdopterin as the organic component of the tungsten cofactor in four enzymes from hyperthermophilic Archaea. 
  • Identification of molybdopterin guanine dinucleotide in formate dehydrogenase from Methanobacterium formicicum. 
  • Identification of the molybdenum cofactor of dimethyl sulfoxide reductase from Rhodobacter sphaeroides f. sp. denitrificans as bis(molybdopterin guanine dinucleotide)molybdenum. 
  • In vitro system for molybdopterin biosynthesis. 
  • Isolation and characterization of a second molybdopterin dinucleotide: molybdopterin cytosine dinucleotide. 
  • Lessons From the Studies of a CC Bond Forming Radical SAM Enzyme in Molybdenum Cofactor Biosynthesis. 
  • Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. 
  • Mechanistic Investigation of cPMP Synthase in Molybdenum Cofactor Biosynthesis Using an Uncleavable Substrate Analogue. 
  • Molybdenum cofactor biosynthesis in Escherichia coli. Requirement of the chlB gene product for the formation of molybdopterin guanine dinucleotide. 
  • Molybdopterin guanine dinucleotide: a modified form of molybdopterin identified in the molybdenum cofactor of dimethyl sulfoxide reductase from Rhodobacter sphaeroides forma specialis denitrificans. 
  • Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons. 
  • Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation. 
  • Novel aspects of the biochemistry of the molybdenum cofactor. 
  • Radical Breakthroughs in Natural Product and Cofactor Biosynthesis. 
  • Resonance Raman spectroscopic characterization of the molybdopterin active site of DMSO reductase. 
  • Specific incorporation of molybdopterin in xanthine dehydrogenase of Pseudomonas aeruginosa. 
  • The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis. 
  • The pterin of the molybdenum cofactor. 
  • The structure of the molybdenum cofactor. Characterization of di-(carboxamidomethyl)molybdopterin from sulfite oxidase and xanthine oxidase.