Pulmonary Circulation

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  Subject Areas on Research

  • A multicenter pilot study of a bronchial valve for the treatment of severe emphysema. 
  • A non-invasive assessment of cardiopulmonary hemodynamics with MRI in pulmonary hypertension. 
  • A simulation-based sensitivity study of radionuclide angiocardiographic approaches to shunt assessment. 
  • Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash. 
  • An analysis of the pulsatile hemodynamic responses of the pulmonary circulation to acute and chronic pulmonary venous hypertension in the awake dog. 
  • Analysis of pulmonary and systemic vascular responses to platelet-activating factor in the cat. 
  • Analysis of responses to bradykinin in the pulmonary vascular bed of the cat. 
  • Analysis of responses to sarafotoxin 6a and sarafotoxin 6c in the pulmonary vascular bed of the cat. 
  • Analysis of responses to serotonin in the pulmonary vascular bed of the cat. 
  • Analysis of responses to substance P in the pulmonary vascular bed of the cat. 
  • Analysis of systemic and pulmonary vascular responses to PACAP and VIP: role of adrenal catecholamines. 
  • Autonomic activation links CNS oxygen toxicity to acute cardiogenic pulmonary injury. 
  • Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest. 
  • Brain death alters cardiopulmonary hemodynamics and impairs right ventricular power reserve against an elevation of pulmonary vascular resistance. 
  • Carbon monoxide promotes hypoxic pulmonary vascular remodeling. 
  • Cerebrocortical oxygenation and ventilatory response during sustained hypoxia. 
  • Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe. 
  • Characterization of thromboxane receptor blocking effects of SQ 29548 in the feline pulmonary vascular bed. 
  • Clinical implications of pulmonary hypertension in mitral stenosis. 
  • Commentary: Ductal stenting for ductal-dependent pulmonary blood flow: Time for an exclusive club to expand its membership? 
  • Commentary: One size fits some-additional pulmonary blood flow at the Glenn operation and patient-specific factors. 
  • Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP. 
  • Comparison of pressor responses to angiotensin I, II, and III in pulmonary vascular bed of cats. 
  • Comparison of right ventricle-pulmonary artery shunt position in the Single Ventricle Reconstruction trial. 
  • Contemporary Outcomes of Surgical Repair of Total Anomalous Pulmonary Venous Connection in Patients With Heterotaxy Syndrome. 
  • Coronary artery-to-pulmonary artery collaterals in chronic thromboembolic pulmonary hypertension. 
  • Correlation between minute carbon dioxide elimination and pulmonary blood flow in single-ventricle patients after stage 1 palliation and 2-ventricle patients with intracardiac shunts: A pilot study. 
  • Daltroban blocks thromboxane responses in the pulmonary vascular bed of the cat. 
  • Depletion of pulmonary intravascular macrophages prevents hyperacute pulmonary xenograft dysfunction. 
  • Design and evaluation of a new, low pressure loss, implantable artificial lung. 
  • Differential effects of PACAP and VIP on the pulmonary and hindquarters vascular beds of the cat. 
  • Diffusion limitation in normal humans during exercise at sea level and simulated altitude. 
  • Distribution of 15- and 137-mu diameter microspheres in the dog lung in the axial plane. 
  • Echo/Doppler and hemodynamic correlates of vasodilator responsiveness in primary pulmonary hypertension. 
  • Echocardiographic estimation of pulmonary vascular resistance in chronic thromboembolic pulmonary hypertension: utility of right heart Doppler measurements. 
  • Effect of cyclooxygenase and lipoxygenase products on pulmonary function in group B streptococcal sepsis. 
  • Effects of U-37883A, a vascular selective KATP+ channel antagonist, in the pulmonary and hindlimb circulation. 
  • Effects of aortopulmonary collaterals on cerebral cooling and cerebral metabolic recovery after circulatory arrest. 
  • Effects of clenbuterol hydrochloride on pulmonary gas exchange and hemodynamics in anesthetized horses. 
  • Effects of head and body cooling on hemodynamics during immersed prone exercise at 1 ATA. 
  • Elevated left atrial pressure does not cause left-to-right shunting after mitral balloon valvuloplasty. 
  • Epinephrine induces rapid deterioration in pulmonary oxygen exchange in intact, anesthetized rats: a flow and pulmonary capillary pressure-dependent phenomenon. 
  • Everything old is new again: transthoracic cardiac catheterization. 
  • Gleaning physiologic information from the conventional chest radiograph. 
  • Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension. 
  • Hemodynamic and inotropic effects of nitric oxide in pulmonary hypertension. 
  • Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. 
  • Hypoxia compared with normoxia alters the effects of nitric oxide in ischemia-reperfusion lung injury. 
  • Images in cardiovascular medicine. Untreated tetralogy of Fallot with pulmonary atresia: giant aneurysm of an aortopulmonary collateral artery demonstrated by magnetic resonance imaging. 
  • Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. 
  • Improving temporal resolution of pulmonary perfusion imaging in rats using the partially separable functions model. 
  • In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency. 
  • Increased wedge pressure facilitates decreased lung vascular resistance during upright exercise. 
  • Influence of SQ 30741 on thromboxane receptor-mediated responses in the feline pulmonary vascular bed. 
  • Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed. 
  • Influence of an antagonist of slow-reacting substance of anaphylaxis on the cardiovascular manifestations of hypoxia in piglets. 
  • Influence of lemakalim on the pulmonary vascular bed of the cat. 
  • Influence of nitroglycerin on splanchnic capacity and splanchnic capacity-cardiac output relationship. 
  • Inhaled epoprostenol during one-lung ventilation. 
  • Inhaled nitric oxide, right ventricular efficiency, and pulmonary vascular mechanics: selective vasodilation of small pulmonary vessels during hypoxic pulmonary vasoconstriction. 
  • Inhibitory effects of DuP 753 and EXP3174 on responses to angiotensin II in pulmonary vascular bed of the cat. 
  • Intrabreath analysis of carbon monoxide uptake during exercise in patients at risk for lung injury. 
  • Intracardiac pressure-flow dynamics in isolated ventricular septal defects. 
  • Kerley B lines in total anomalous pulmonaru venous connection below the diaphragm (type 3). 
  • Low-flow cardiopulmonary bypass produces greater pulmonary dysfunction than circulatory arrest. 
  • Mechanisms of hyperoxic injury to the pulmonary microcirculation. 
  • Mediators of pulmonary injury induced by inhalation of bacterial endotoxin. 
  • Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus. 
  • Methylene blue inhibits neurogenic cholinergic vasodilator responses in the pulmonary vascular bed of the cat. 
  • Milrinone improves pulmonary hemodynamics and right ventricular function in chronic pulmonary hypertension. 
  • Mitochondrial biogenesis in the pulmonary vasculature during inhalational lung injury and fibrosis. 
  • Mitral flow propagation velocity identifies patients with abnormal diastolic function during coronary artery bypass graft surgery. 
  • Modulation of cytokines and chemokines, limited pulmonary vascular bed permeability, and prevention of septicemia and death with ceftriaxone and interleukin-10 in pneumococcal pneumonia. 
  • Molecular and functional mechanisms of right ventricular adaptation in chronic pulmonary hypertension. 
  • Myocardial energetics and blood flow in acute rapid ventricular pacing. 
  • N omega-nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin. 
  • NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. 
  • Natural surfactant and hyperoxic lung injury in primates. I. Physiology and biochemistry. 
  • Normal values for single exhalation diffusing capacity and pulmonary capillary blood flow in sitting, supine positions, and during mild exercise. 
  • Novel Approaches to Imaging the Pulmonary Vasculature and Right Heart. 
  • Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells. 
  • PO2-dependent hydroxyl radical production during ischemia-reperfusion lung injury. 
  • Patient and tumor characteristics predictive of an elevated hepatopulmonary shunt fraction before radioembolization of hepatic tumors. 
  • Perioperative Diastolic Dysfunction: A Comprehensive Approach to Assessment by Transesophageal Echocardiography. 
  • Peripheral middle lobe syndrome. 
  • Pharmacologic reduction of pretransplantation pulmonary vascular resistance predicts outcome after pediatric heart transplantation. 
  • Phenylephrine-modulated cardiopulmonary blood flow measured with use of X-ray digital subtraction angiography. 
  • Portopulmonary Hypertension and Liver Transplant: Recent Review of the Literature. 
  • Preprocedural three-dimensional planning aids in transcatheter ductal stent placement: A single-center experience. 
  • Pulmonary Venous Waveforms Predict Rehospitalization and Mortality After Percutaneous Mitral Valve Repair. 
  • Pulmonary endarterectomy: experience and lessons learned in 1,500 cases. 
  • Pulmonary flow study predicts survival in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries. 
  • Pulmonary gas exchange in diving. 
  • Pulmonary hemodynamics and blood flow characteristics in chronic pulmonary hypertension. 
  • Pulmonary hypertension and cor pulmonale. 
  • Pulmonary hypertension and elevated transpulmonary gradient in patients with mitral stenosis. 
  • Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe. 
  • Pulmonary vascular and airway responses to endothelin-1 are mediated by different mechanisms in the cat. 
  • Pulmonary vascular impedance analysis of adaptation to chronically elevated blood flow in the awake dog. 
  • Pulmonary vascular steal in chronic thromboembolic pulmonary hypertension. 
  • Pulmonary vascularity: radiographic considerations. 
  • Pulmonary vasodilator response to vagal stimulation is blocked by N omega-nitro-L-arginine methyl ester in the cat. 
  • Pulmonary vasodilator responses to RP 52891 are mediated by activation of a glibenclamide-sensitive K+ATP channel. 
  • Pulmonary venous wedge pressure provides a safe and accurate estimate of pulmonary arterial pressure in children with shunt-dependent pulmonary blood flow. 
  • Pulmonary wedge catheter. 
  • Purine nucleotides contribute to pulmonary vasodilation caused by birth-related stimuli in the ovine fetus. 
  • Radiographic analysis of pulmonary vascular distribution: a review. 
  • Redistribution of pulmonary blood flow secondary to pulmonary arterial hypertension. 
  • Regional pulmonary distribution of iodine-125-labeled oleic acid. Its relationship to the pattern of oleic acid edema and pulmonary blood flow. 
  • Relevance of B-Lines on Lung Ultrasound in Volume Overload and Pulmonary Congestion: Clinical Correlations and Outcomes in Patients on Hemodialysis. 
  • Responses to propofol in the pulmonary vascular bed of the rat. 
  • Rest and exercise cardiac output and diffusing capacity assessed by a single slow exhalation of methane, acetylene, and carbon monoxide. 
  • Resting pulmonary haemodynamics and shunting: a comparison of sea-level inhabitants to high altitude Sherpas. 
  • Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. 
  • Right ventricular dysfunction in the brain-dead heart-beating organ donor. 
  • Risk factors for pulmonary thromboendarterectomy. 
  • Role of K+ATP channels and EDRF in reactive hyperemia in the hindquarters vascular bed of cats. 
  • Surgical pulmonary embolectomy and catheter-based therapies for acute pulmonary embolism: A contemporary systematic review. 
  • TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction. 
  • TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. 
  • The Fontan right atrium--in context. 
  • The effect of patient-specific factors on radiation-induced regional lung injury. 
  • The effects of airway pressure on cardiac function in intact dogs and man. 
  • The efficiency of pulmonary blood transport following single lung transplantation. 
  • The transition from fetal to neonatal circulation: normal responses and implications for infants with heart disease. 
  • Total respiratory support from swine lungs in primate recipients. 
  • Tumor necrosis factor-alpha-induced lung injury and its modulation by synthetic polynucleotide: a physiologic-morphometric analysis. 
  • Utilization of inhaled nitric oxide after surgical repair of truncus arteriosus: A multicenter analysis. 
  • Validation of haemodialysis recirculation and access blood flow measured by thermodilution. 
  • Vascular release of nonheme iron in perfused rabbit lungs. 
  • Vascular remodeling--the emerging paradigm of programmed cell death (apoptosis): the Francis B. Parker lectureship. 
  • Ventilation-perfusion inequality in normal humans during exercise at sea level and simulated altitude. 
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  Keywords of People

  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Ghadimi, Kamrouz, Associate Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • Moon, Richard Edward, Professor of Anesthesiology, Medicine, Pulmonary, Allergy, and Critical Care Medicine