Pulmonary Fibrosis

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  Subject Areas on Research

  • 3D MRI of impaired hyperpolarized 129Xe uptake in a rat model of pulmonary fibrosis. 
  • A Conserved Distal Lung Regenerative Pathway in Acute Lung Injury. 
  • A Heterotopic Xenograft Model of Human Airways for Investigating Fibrosis in Asthma. 
  • A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice. 
  • Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival. 
  • Actions of thrombin in the interstitium. 
  • Acute interstitial pneumonia. 
  • Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis. 
  • Anti-fibrotic effects of different sources of MSC in bleomycin-induced lung fibrosis in C57BL6 male mice. 
  • Asbestos bodies in bronchoalveolar lavage fluid. A study of 20 asbestos-exposed individuals and comparison to patients with other chronic interstitial lung diseases. 
  • Asbestos content of lung tissue in asbestos associated diseases: a study of 110 cases. 
  • Asbestos fiber content of lungs with diffuse interstitial fibrosis: An analytical scanning electron microscopic analysis of 249 cases. 
  • Aspiration of metallic mercury. A 22-year follow-up. 
  • Atrial fibrillation after pulmonary transplant. 
  • Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice. 
  • Bronchiectasis: Mechanisms and Imaging Clues of Associated Common and Uncommon Diseases. 
  • Bronchiolitis by Any Other Name: Describing Bronchiolar Disorders from Inhalational Exposures. 
  • Bronchogenic carcinoma after lung transplantation: frequency, clinical characteristics, and imaging findings. 
  • Busulfan and cyclophosphamide as a preparative regimen for bone marrow transplantation in patients with prior chest radiotherapy. 
  • CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. 
  • CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model. 
  • CT of the lung: patterns of calcification and other high-attenuation abnormalities. 
  • Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. 
  • Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis. 
  • Changing trends in marrow transplantation for aplastic anemia. 
  • Characterization of the innate immune response to chronic aspiration in a novel rodent model. 
  • Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins. 
  • Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials. 
  • Dendriform pulmonary ossification. Report of two cases with unique findings. 
  • Detection of silica particles in lung tissue by polarizing light microscopy. 
  • Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans. 
  • Early and late interstitial pneumonia following human bone marrow transplantation. 
  • Effect of erionite on the pleural mesothelium of the Fischer 344 rat. 
  • Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus. 
  • Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease. 
  • Familial pulmonary fibrosis in the United States. 
  • Fibrosing alveolitis in patients with neurofibromatosis. 
  • Gene expression profiling of familial and sporadic interstitial pneumonia. 
  • Giant cell interstitial pneumonia in a hard-metal worker. Cytologic, histologic and analytical electron microscopic investigation. 
  • Giant cell interstitial pneumonia in patients without hard metal exposure: analysis of 3 cases and review of the literature. 
  • Giant cell interstitial pneumonia secondary to cobalt exposure from e-cigarette use. 
  • Graft-versus-host disease as adoptive immunotherapy in patients with advanced hematologic neoplasms. 
  • Hyperacute graft-v-host disease in patients not given immunosuppression after allogeneic marrow transplantation. 
  • IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease. 
  • Immediate Release of Gastrin-Releasing Peptide Mediates Delayed Radiation-Induced Pulmonary Fibrosis. 
  • Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection. 
  • Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin in bone marrow transplantation. 
  • Induction of tenascin in rat lungs undergoing bleomycin-induced pulmonary fibrosis. 
  • Inhaled carbon nanotubes reach the subpleural tissue in mice. 
  • Intercellular adhesion molecule-1 and L-selectin regulate bleomycin-induced lung fibrosis. 
  • Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma. 
  • Interstitial lung disease and domestic wood burning. 
  • Intravenous drug use fools us again. The importance of open lung biopsy in evaluating a patient with progressive interstitial lung disease presenting with pneumothorax. 
  • Kaposi sarcoma after bilateral lung transplantation. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • Large-Scale Characterization of Systemic Sclerosis Serum Protein Profile: Comparison to Peripheral Blood Cell Transcriptome and Correlations With Skin/Lung Fibrosis. 
  • Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. 
  • Living-related lobar lung transplantation. 
  • Long-term efficacy and safety of 12 months of valganciclovir prophylaxis compared with 3 months after lung transplantation: a single-center, long-term follow-up analysis from a randomized, controlled cytomegalovirus prevention trial. 
  • Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants. 
  • Marrow transplantation for acute nonlymphoblastic leukemia in first remission: toxicity and long-term follow-up of patients conditioned with single dose or fractionated total body irradiation. 
  • Marrow transplantation with or without donor buffy coat cells for 65 transfused aplastic anemia patients. 
  • Measuring diffusion limitation with a perfusion-limited gas--hyperpolarized 129Xe gas-transfer spectroscopy in patients with idiopathic pulmonary fibrosis. 
  • Mitochondrial biogenesis in the pulmonary vasculature during inhalational lung injury and fibrosis. 
  • Mosaic Attenuation: Etiology, Methods of Differentiation, and Pitfalls. 
  • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. 
  • Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). 
  • Organs at Risk Considerations for Thoracic Stereotactic Body Radiation Therapy: What Is Safe for Lung Parenchyma? 
  • Osteopontin expression in particle-induced lung disease. 
  • Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury. 
  • Pathologic findings and long-term sequelae in Legionnaires' disease. 
  • Pathology of Asbestosis: An Update of the Diagnostic Criteria Response to a Critique. 
  • Pathology of asbestosis- An update of the diagnostic criteria: Report of the asbestosis committee of the college of american pathologists and pulmonary pathology society. 
  • Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis. 
  • Persistent or recurrent bronchogenic carcinoma: detection with PET and 2-[F-18]-2-deoxy-D-glucose. 
  • Pharmacokinetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia. 
  • Pneumonia in bone marrow transplant patients. 
  • Pneumonitis complicating low-dose methotrexate therapy in rheumatoid arthritis. 
  • Polyclonal polymorphic B-cell lymphoproliferative disorder with prominent pulmonary involvement in children with acquired immune deficiency syndrome. 
  • Positron emission tomography imaging of the thorax. 
  • Pre-transplant panel reactive antibody in lung transplant recipients is associated with significantly worse post-transplant survival in a multicenter study. 
  • Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis. 
  • Progression of idiopathic pulmonary fibrosis in native lungs after single lung transplantation. 
  • Progressive multifocal leukoencephalopathy following heightened immunosuppression after lung transplant. 
  • Prophylaxis of infection in patients with aplastic anemia receiving allogeneic marrow transplants. 
  • Pulmonary alveolar proteinosis with interstitial involvement. 
  • Pulmonary apical cap. 
  • Pulmonary capillary wedge pressure augments right ventricular pulsatile loading. 
  • Pulmonary drug toxicity following high-dose chemotherapy with autologous bone marrow transplantation: CT findings in 20 cases. 
  • Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos. 
  • Pulmonary fibrosis and ferruginous bodies associated with exposure to synthetic fibers. 
  • Pulmonary fibrosis, carcinoma, and ferruginous body counts in amosite asbestos workers. A study of six cases. 
  • Pulmonary fibrosis: patterns and perpetrators. 
  • Pulmonary fibrosis: thinking outside of the lung. 
  • Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors. 
  • Pulmonary nontuberculous mycobacterial infection: radiologic manifestations. 
  • Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury. 
  • Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation. 
  • Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis. 
  • Sample size for a two-group comparison of repeated binary measurements using GEE. 
  • Scanning electron microscopic analysis of mineral fiber content of lung tissue in the evaluation of diffuse pulmonary fibrosis. 
  • Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats. 
  • Significance of bronchiolocentric fibrosis in patients with histopathological usual interstitial pneumonia. 
  • Sildenafil improves walk distance in idiopathic pulmonary fibrosis. 
  • Simultaneous bilateral lung and pancreas transplantation in recipient with cystic fibrosis. 
  • Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. 
  • Surgical considerations in lung transplantation: transplant operation and early postoperative management. 
  • Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. 
  • Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. 
  • Targeting Inhibitor of Apoptosis Proteins Protects from Bleomycin-Induced Lung Fibrosis. 
  • Testicular cancer survivorship: research strategies and recommendations. 
  • The Role of Surgical Lung Biopsy in the Diagnosis of Fibrotic Interstitial Lung Disease: Perspective from the Pulmonary Fibrosis Foundation. 
  • The So-called Short-Fiber Controversy: Literature Review and Critical Analysis. 
  • The role of soluble and insoluble gastric fluid components in the pathogenesis of obliterative bronchiolitis in rat lung allografts. 
  • The wait for the waitlist: The next challenge in the lung allocation system. 
  • Treatment of chronic granulocytic leukaemia in chronic phase by allogeneic marrow transplantation. 
  • Treatment of human acute graft-versus-host disease with antithymocyte globulin and cyclosporine with or without methylprednisolone. 
  • Treatment of non-Hodgkin's lymphoma with chemoradiotherapy and allogenic marrow transplantation. 
  • Upper lobe fibrosis: a novel manifestation of chronic allograft dysfunction in lung transplantation. 
  • Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases. 
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  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Tata, Purushothama Rao, Assistant Professor of Cell Biology, Cell Biology
  • Tighe, Robert Matthew, Associate Professor of Medicine, Environmental Sciences and Policy