Pyridazines
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Subject Areas on Research
- A Randomized, Controlled Pharmacokinetic and Pharmacodynamics Trial of Ambrisentan After Fontan Surgery.
- A circuit model for saccadic suppression in the superior colliculus.
- A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia.
- An in vitro study of horizontal connections in the intermediate layer of the superior colliculus.
- Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitude.
- Better late than never: a welcome publication of tardy clinical trial results.
- Comparison of cinoxacin and nalidixic acid in patients with cystitis.
- Comparison of low-dose cinoxacin therapy and placebo in the prevention of recurrent urinary tract infections.
- DUCCS and SWANS: when U.S. site-based research was highly successful.
- Dead letter office.
- Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.
- Distribution of GABAA receptors in the limbic system of alcohol-preferring and non-preferring rats: in situ hybridisation histochemistry and receptor autoradiography.
- Drug susceptibility and resistance mutations after first-line failure in resource limited settings.
- Effect of levosimendan on survival and adverse events after cardiac surgery: a meta-analysis.
- EndothelinA receptor antagonist BSF-208075 causes immune modulation and neuroprotection after stroke in gerbils.
- Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity.
- Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon.
- Initial testing (stage 1) of SGI-1776, a PIM1 kinase inhibitor, by the pediatric preclinical testing program.
- Inotropes in the management of acute heart failure.
- Levosimendan in Cardiac Surgery.
- Levosimendan in Cardiac Surgery.
- Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery.
- Levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary bypass: Rationale and study design of the Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass (LEVO-CTS) trial.
- Long-lived polarization protected by symmetry.
- Low excitatory innervation balances high intrinsic excitability of immature dentate neurons.
- Manipulation of small-molecule inhibitory kinetics modulates MCH-R1 function.
- Mechanism of the luminol-dependent chemiluminescence of human neutrophils.
- Pan-PIM kinase inhibitors enhance Lenalidomide's anti-myeloma activity via cereblon-IKZF1/3 cascade.
- Postsynaptic mechanisms govern the differential excitation of cortical neurons by thalamic inputs.
- Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/NMDA antagonist: an in vivo three-dimensional diffusion-weighted MR microscopy study.
- Pyridazinones as selective cyclooxygenase-2 inhibitors.
- Rapid down-regulation of GABAA receptors in the gerbil hippocampus following transient cerebral ischemia.
- Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.
- Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia.
- Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors.
- TT-301 inhibits microglial activation and improves outcome after central nervous system injury in adult mice.
- The combination of theophylline and endothelin receptor antagonism improves exercise performance of rats under simulated high altitude.
- The disconnect between phase II and phase III trials of drugs for heart failure.
- Thyroid Hormones and Thyromimetics: A New Approach to Nonalcoholic Steatohepatitis?
- Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial.
- Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.
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Keywords of People
- Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology