Pyrimidine Dimers

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  Subject Areas on Research

  • A hot spot for hydrogen peroxide-induced damage in the human hypoxia-inducible factor 1 binding site of the PGK 1 gene. 
  • A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation. 
  • Accelerated deamination of cytosine residues in UV-induced cyclobutane pyrimidine dimers leads to CC-->TT transitions. 
  • Adenine Fine-Tunes DNA Photolyase's Repair Mechanism. 
  • Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events. 
  • KIND1 Loss Sensitizes Keratinocytes to UV-Induced Inflammatory Response and DNA Damage. 
  • No detectable DNA excision repair in UV-exposed hepatocytes from two catfish species. 
  • Reaction mechanism of human DNA repair excision nuclease. 
  • Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. 
  • Structure and function of the UvrB protein. 
  • The other function of DNA photolyase: stimulation of excision repair of chemical damage to DNA. 
  • UV photoprotection by combination topical antioxidants vitamin C and vitamin E. 
  • UVA generates pyrimidine dimers in DNA directly.