-
Subject Areas on Research
-
A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: The PRIORITIZE Study.
-
A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice.
-
A highly selective inhibitor of IkappaB kinase, BMS-345541, augments graft survival mediated by suboptimal immunosuppression in a murine model of cardiac graft rejection.
-
A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
-
Adapting smoking cessation treatment according to initial response to precessation nicotine patch.
-
An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice.
-
Androgens modulate NMDA receptor-mediated EPSCs in the zebra finch song system.
-
Anisodamine at higher concentrations in inhibiting alpha-adrenergic responses in isolated canine blood vessels.
-
Attenuation of hippocampal long-term potentiation by ethanol: a patch-clamp analysis of glutamatergic and GABAergic mechanisms.
-
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
-
BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.
-
Bilateral angle closure following use of a weight loss combination agent containing topiramate.
-
Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.
-
Combination treatment with varenicline and bupropion in an adaptive smoking cessation paradigm.
-
Concentration-related effects of nitric oxide and endothelin-1 on human trabecular meshwork cell contractility.
-
Consequences of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor blockade during status epilepticus in the developing brain.
-
Deconstructing behavioral neuropharmacology with cellular specificity.
-
Development of intrinsic and synaptic properties in a forebrain nucleus essential to avian song learning.
-
Dietary mutagen exposure and risk of pancreatic cancer.
-
Differential actions of diazepam and zolpidem in basolateral and central amygdala nuclei.
-
Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes.
-
Differential effect of ethanol on NMDA EPSCs in pyramidal cells in the posterior cingulate cortex of juvenile and adult rats.
-
Differential sensitivity of GABA A receptor-mediated IPSCs to cannabinoids in hippocampal slices from adolescent and adult rats.
-
Discrimination of post- and presynaptic GABAB receptor-mediated responses by tetrahydroaminoacridine in area CA3 of the rat hippocampus.
-
Diurnal and nocturnal effects of brimonidine monotherapy on intraocular pressure.
-
Effects of NMDA receptor glycine recognition site antagonism on cerebral metabolic rate for glucose and cerebral blood flow in the conscious rat.
-
Effects of varenicline and cognitive bias modification on neural response to smoking-related cues: study protocol for a randomized controlled study.
-
Eight Weeks of Treatment With Glecaprevir/Pibrentasvir Is Safe and Efficacious in an Integrated Analysis of Treatment-Naïve Patients With Hepatitis C Virus Infection.
-
Enantiomeric separation of an aryloxyphenoxypropanoic acid by CE and LC.
-
Ethanol and magnesium ions inhibit N-methyl-D-aspartate-mediated synaptic potentials in an interactive manner.
-
Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons.
-
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
-
GABAB autoreceptors mediate activity-dependent disinhibition and enhance signal transmission in the dentate gyrus.
-
GABAB-receptor-mediated inhibition of the N-methyl-D-aspartate component of synaptic transmission in the rat hippocampus.
-
Glecaprevir and pibrentasvir yield high response rates in patients with HCV genotype 1-6 without cirrhosis.
-
Glycine antagonism does not block ischemic spontaneous depolarization in the rat.
-
High-frequency organization and synchrony of activity in the purkinje cell layer of the cerebellum.
-
IKK mediates ischemia-induced neuronal death.
-
Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity.
-
In vivo models of cerebral ischemia: effects of parenterally administered NMDA receptor glycine site antagonists.
-
Inhibition of inhibition in visual cortex: the logic of connections between molecularly distinct interneurons.
-
Initial testing (stage 1) of the phosphatidylinositol 3' kinase inhibitor, SAR245408 (XL147) by the pediatric preclinical testing program.
-
Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
-
Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy.
-
Long-term effects of excitatory amino acid antagonists NBQX and MK-801 on the developing brain.
-
MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways.
-
Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths.
-
Mu opioid receptor-mediated modulation of synaptic currents in dentate granule cells of rat hippocampus.
-
NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells.
-
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
-
Neuroprotective effect of NMDA receptor glycine recognition site antagonism persists when brain temperature is controlled.
-
Neuroprotective effects of NMDA receptor glycine recognition site antagonism: dependence on glycine concentration.
-
New Treatment Options for Hepatitis C Virus Infection in End-Stage Kidney Disease: To Treat or Not to Treat.
-
New findings on nicotine addiction and treatment.
-
Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress.
-
Optimal Timing of Administration of Direct-acting Antivirals for Patients With Hepatitis C-associated Hepatocellular Carcinoma Undergoing Liver Transplantation.
-
Patient engagement and study design of PROP UP: A multi-site patient-centered prospective observational study of patients undergoing hepatitis C treatment.
-
Patient-reported symptoms during and after direct-acting antiviral therapies for chronic hepatitis C: The PROP UP study.
-
Phase I/II dose-escalation study of PI3K inhibitors pilaralisib or voxtalisib in combination with letrozole in patients with hormone-receptor-positive and HER2-negative metastatic breast cancer refractory to a non-steroidal aromatase inhibitor.
-
Potentiometric, electronic structural, and ground- and excited-state optical properties of conjugated bis[(porphinato)zinc(II)] compounds featuring proquinoidal spacer units.
-
Pre-cessation varenicline treatment vs post-cessation NRT: an uneven playing field.
-
Rapid assessment of cardiovascular risk among users of smoking cessation drugs within the US Food and Drug Administration's Mini-Sentinel program.
-
Reduced sensitivity of the N-methyl-D-aspartate component of synaptic transmission to magnesium in hippocampal slices from immature rats.
-
Relative contributions of rod and cone bipolar cell inputs to AII amacrine cell light responses in the mouse retina.
-
Response to Gorelick.
-
Role of NMDA, non-NMDA, and GABA receptors in signal propagation in the amygdala formation.
-
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors.
-
Safety and efficacy of brimonidine in children with glaucoma.
-
Simplified monitoring for hepatitis C virus treatment with glecaprevir plus pibrentasvir, a randomised non-inferiority trial.
-
Smoking quit success genotype score predicts quit success and distinct patterns of developmental involvement with common addictive substances.
-
Successful management of orbital cellulitis and temporary visual loss after blepharoplasty.
-
Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex.
-
Sustainable and equivalent improvements in symptoms and functional well-being following viral cure from ledipasvir/sofosbuvir versus elbasvir/grazoprevir for chronic hepatitis C infection: Findings from the randomized PRIORITIZE trial.
-
Synaptic basis for developmental plasticity in a birdsong nucleus.
-
The HVC microcircuit: the synaptic basis for interactions between song motor and vocal plasticity pathways.
-
The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice.
-
Tonopen measurement of intraocular pressure in mice.
-
Treatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, Conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquine.
-
Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats.
-
Two-photon absorption properties of proquinoidal D-A-D and A-D-A quadrupolar chromophores.
-
Varenicline effects on craving, cue reactivity, and smoking reward.
-
Varenicline-induced drug eruption with resulting palmar/plantar hyperhidrosis and dysesthesia.
-
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.