Radiation-Protective Agents
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Subject Areas on Research
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A Phase II trial of subcutaneous amifostine and radiation therapy in patients with head-and-neck cancer.
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A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.
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A randomized trial of amifostine and carmustine-containing chemotherapy to assess lung-protective effects.
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Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE).
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Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion.
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Are We Ready for a Radiological Terrorist Attack Yet? Report From the Centers for Medical Countermeasures Against Radiation Network.
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Assessment and management of cutaneous reactions with amifostine administration: findings of the ethyol (amifostine) cutaneous treatment advisory panel (ECTAP).
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Assessment of the protective effect of amifostine on radiation-induced pulmonary toxicity.
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CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5.
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Chemoprevention agents for melanoma: A path forward into phase 3 clinical trials.
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Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation.
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Clarifying the Relative Impacts of Vascular and Nerve Injury That Culminate in Erectile Dysfunction in a Pilot Study Using a Rat Model of Prostate Irradiation and a Thrombopoietin Mimetic.
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Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection.
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Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary.
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Cytoprotection for radiation-associated normal tissue injury.
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Does amifostine have a role in chemoradiation treatment?
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Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage.
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Effect of a metalloporphyrin antioxidant (MnTE-2-PyP) on the response of a mouse prostate cancer model to radiation.
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Effect of amifostine on patient assessed clinical benefit in irradiated head and neck cancer.
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Effect of amifostine on survival among patients treated with radiotherapy: a meta-analysis of individual patient data.
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Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin.
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Future directions in toxicity prevention.
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Future directions in toxicity prevention.
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Has the outlook improved for amifostine as a clinical radioprotector.
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Influence of WR 2721 on radiation response of canine soft tissue sarcomas.
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Influence of intravenous amifostine on xerostomia, tumor control, and survival after radiotherapy for head-and- neck cancer: 2-year follow-up of a prospective, randomized, phase III trial.
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Inhibition of the Continuum of Radiation-Induced Normal Tissue Injury by a Redox-Active Mn Porphyrin.
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Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.
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Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain.
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Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.
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Modulation of ultraviolet light-induced epidermal damage: beneficial effects of tocopherol.
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Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model.
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Pharmacologic approaches to radiation protection.
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Phase III randomized trial of amifostine as a radioprotector in head and neck cancer.
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Phase III randomized trial of amifostine as a radioprotector in head and neck cancer.
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Prevention and treatment of sunburn.
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Proteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+).
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Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model.
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Radiation effects and radioprotection in MC3T3-E1 mouse calvarial osteoblastic cells.
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Radioprotection of lipogenesis from glucose (U-14C) and activities of pyridine nucleotide dehydrogenases in liver of gamma-irradiated female rats by cystamine.
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Radioprotection of liver lipids of whole-body gamma-irradiated female rats by cystamine.
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Radioprotection of lungs by amifostine is associated with reduction in profibrogenic cytokine activity.
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Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+.
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Radioprotective effects of amifostine on acute and chronic esophageal injury in rodents.
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Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.
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Rapid measurement of total body water to facilitate clinical decision making in hospitalized elderly patients.
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Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).
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Spleen lipids: effect of whole body gamma irradiation and radioprotective chemicals.
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Strategies for optimizing the response of cancer and normal tissues to radiation.
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Superoxide dismutase mimic, MnTE-2-PyP(5+) ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum.
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The Toll-Like Receptor 2/6 Agonist, FSL-1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome.
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The antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation.
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The protective effect of recombinant human keratinocyte growth factor on radiation-induced pulmonary toxicity in rats.
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The role of amifostine as a radioprotector.
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Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
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Toxicity, biodistribution and radioprotective capacity of L-homocysteine thiolactone in CNS tissues and tumors in rodents: comparison with prior results with phosphorothioates.
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Ubiquinone, idebenone, and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid.
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Utilizing Superoxide Dismutase Mimetics to Enhance Radiation Therapy Response While Protecting Normal Tissues.
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