Radiation-Sensitizing Agents
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Subject Areas on Research
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4-Fluorobenzylamine and phenylalanine methyl ester conjugates of 2-nitroimidazole: evaluation as hypoxic cell radiosensitizers.
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A detrimental effect of a combined chemotherapy-radiotherapy approach in children with diffuse intrinsic brain stem gliomas?
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A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.
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A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation.
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Ability of C-reactive protein to complement multiple prognostic classifiers in men with metastatic castration resistant prostate cancer receiving docetaxel-based chemotherapy.
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Adjuvant radiotherapy with and without concurrent chemotherapy for locally advanced transitional cell carcinoma of the renal pelvis and ureter.
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Analyzing cell cycle checkpoints after ionizing radiation.
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Anemia is associated with decreased survival and increased locoregional failure in patients with locally advanced head and neck carcinoma: a secondary analysis of RTOG 85-27.
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Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize.
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Assessing the ability of the antiangiogenic and anticytokine agent thalidomide to modulate radiation-induced lung injury.
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Bromodeoxyuridine-mediated radiosensitization in human glioma: the effect of concentration, duration, and fluoropyrimidine modulation.
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Changes on Midchemoradiation Therapy Fluorodeoxyglucose Positron Emission Tomography for Cervical Cancer Are Associated with Prognosis.
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Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer.
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Combined treatment approaches in regionally advanced bladder cancer.
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Combining gemcitabine with radiation in pancreatic cancer: understanding important variables influencing the therapeutic index.
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Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary.
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Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.
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Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(II) N-alkylpyridylporphyrins.
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Effects of pentobarbital anesthesia on the energy metabolism of murine tumors studied by in vivo 31P nuclear magnetic resonance spectroscopy.
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Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats.
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Efficacy endpoints of radiation therapy group protocol 0247: a randomized, phase 2 study of neoadjuvant radiation therapy plus concurrent capecitabine and irinotecan or capecitabine and oxaliplatin for patients with locally advanced rectal cancer.
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Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia.
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Factors influencing hyperthermic enhancement of drug cytotoxicity.
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Feasibility of laser targeted photo-occlusion of ocular vessels.
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GBM radiosensitizers: dead in the water…or just the beginning?
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Halogenated pyrimidine sensitization of low dose rate irradiation in human malignant glioma.
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Hypoxia in the thymus: role of oxygen tension in thymocyte survival.
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Immunonanoshells for targeted photothermal ablation in medulloblastoma and glioma: an in vitro evaluation using human cell lines.
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Improved survival in stage III non-small-cell lung cancer: seven-year follow-up of cancer and leukemia group B (CALGB) 8433 trial.
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Improving DNA double-strand repair inhibitor KU55933 therapeutic index in cancer radiotherapy using nanoparticle drug delivery.
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Improving the Predictive Value of Preclinical Studies in Support of Radiotherapy Clinical Trials.
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Initial testing of JNJ-26854165 (Serdemetan) by the pediatric preclinical testing program.
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Investigating a chimeric anti-mouse PDGFRα antibody as a radiosensitizer in primary mouse sarcomas.
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Is hyperbaric oxygen more effective than carbogen/nicotinamide in tumor radiation response?
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Is the therapeutic index better with gemcitabine-based chemoradiation than with 5-fluorouracil-based chemoradiation in locally advanced pancreatic cancer?
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L-buthionine-sulfoximine-mediated radiosensitization in experimental interstitial radiotherapy of intracerebral D-54 MG glioma xenografts in athymic mice.
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Long-term survival of nasopharyngeal carcinoma following concomitant radiotherapy and chemotherapy.
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Management of locally advanced adenocarcinoma of the pancreas.
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Mechanism of the Antitumor and Radiosensitizing Effects of a Manganese Porphyrin, MnHex-2-PyP.
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Motexafin gadolinium: a clinical review of a novel radioenhancer for brain tumors.
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Nanoparticle formulations of histone deacetylase inhibitors for effective chemoradiotherapy in solid tumors.
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Neoadjuvant chemoradiation for adenocarcinoma of the pancreas.
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Neoadjuvant chemoradiation for adenocarcinoma of the pancreas.
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New applications of gemcitabine and future directions in the management of pancreatic cancer.
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New radiotherapy and chemoradiotherapy approaches for non-small-cell lung cancer.
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Notch promotes radioresistance of glioma stem cells.
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Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model.
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Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents.
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Pharmacoeconomics, quality of life, and combination modalities in non-small cell lung cancer: a panel discussion (Part 2).
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Preclinical evaluation of Genexol-PM, a nanoparticle formulation of paclitaxel, as a novel radiosensitizer for the treatment of non-small cell lung cancer.
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Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas.
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Preoperative chemoradiation coupled with aggressive resection as needed ensures near total control in advanced head and neck cancer.
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Preoperative chemoradiation strategies for localized adenocarcinoma of the pancreas.
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Radio-induced modulation of transforming growth factor beta1 sensitivity in a p53 wild-type human colorectal-cancer cell line.
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Radiosensitization of chemotherapy-refractory, locally advanced or locally recurrent breast cancer with trastuzumab: a phase II trial.
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Radiosensitization with carboplatin for patients with unresectable stage III non-small-cell lung cancer: a phase III trial of the Cancer and Leukemia Group B and the Eastern Cooperative Oncology Group.
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Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery.
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Selective laser-activated lesioning of prelabeled fetal hippocampal grafts by intracellular photolytic chromophore.
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Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor.
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Strategies for optimizing the response of cancer and normal tissues to radiation.
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The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma.
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The effect of the perflubron emulsion Oxygent on the calibration characteristics of polarographic oxygen electrodes.
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The effects of hyperoxic and hypercarbic gases on tumour blood flow.
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The in vitro radiosensitization of human glioblastoma with pentoxifylline.
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The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine.
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Therapeutic effect of infused Fluosol-DA/carbogen with ephedrine, flunarizine, or nitroprusside.
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Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression.
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Toxicity and efficacy of concurrent gemcitabine and radiotherapy for locally advanced pancreatic cancer.
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Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy.
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Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery.
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Unresectable hepatocellular carcinoma treated with radiotherapy and/or chemoembolization.
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Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs.
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Utilizing Superoxide Dismutase Mimetics to Enhance Radiation Therapy Response While Protecting Normal Tissues.
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Variability in blood flow and pO2 in tumors in response to carbogen breathing.
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Whole body hyperthermia and heat-sensitizing drugs: a pilot study in canine lymphoproliferative disease.