Radiation, Ionizing

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  Subject Areas on Research

  • A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation. 
  • A limited bibliography of the Federal Government-funded human radiation experiments. 
  • A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. 
  • ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. 
  • Accidental or intentional exposure to ionizing radiation: biodosimetry and treatment options. 
  • Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. 
  • Analyzing cell cycle checkpoints after ionizing radiation. 
  • Assaying Radiosensitivity of Ataxia-Telangiectasia. 
  • Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis. 
  • Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures. 
  • Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae. 
  • Characterization of human Gadd45, a p53-regulated protein. 
  • Childhood cancer and occupational radiation exposure in parents. 
  • Children, medical radiation and the environment: An important dialogue. 
  • Compendium of resources for radiation safety in medical imaging using ionizing radiation. 
  • Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. 
  • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. 
  • Demographic analysis and modeling of human populations exposed to ionizing radiation. 
  • Dental x-rays and risk of meningioma. 
  • Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. 
  • Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. 
  • Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. 
  • Effects of low level ionising radiations. 
  • Environmental factors in relation to breast cancer characterized by p53 protein expression. 
  • First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation. 
  • Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. 
  • Gene expression signatures that predict radiation exposure in mice and humans. 
  • ICRP Publication 113. Education and training in radiological protection for diagnostic and interventional procedures. 
  • INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice. 
  • Identification of a DNA Damage-Induced Alternative Splicing Pathway That Regulates p53 and Cellular Senescence Markers. 
  • Impact of early life exposure to ionizing radiation on influenza vaccine response in an elderly Japanese cohort. 
  • Induction of tissue-type plasminogen activator and 72-kDa type-IV collagenase by ionizing radiation in rat astrocytes. 
  • Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. 
  • Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. 
  • Ionizing radiation exposure to patients admitted with acute myocardial infarction in the United States. 
  • Late Effects of Exposure to Ionizing Radiation and Age on Human Thymus Morphology and Function. 
  • Long-term cellular effects in humans chronically exposed to ionizing radiation. 
  • Medical care in long-term survivors of childhood cancer: a report from the childhood cancer survivor study. 
  • Medical radiation exposure in the U.S. in 2006: preliminary results. 
  • Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review. 
  • Modeling deterministic effects in hematopoietic system caused by chronic exposure to ionizing radiation in large human cohorts. 
  • Modeling hematopoietic system response caused by chronic exposure to ionizing radiation. 
  • Modeling the effects of biologically incorporated radionuclides and chronic low-dose ionizing radiation exposure on both cancer and chronic non-cancer diseases. 
  • Need radioprotection? A MEPE/OF45 mimetic may do the job. 
  • Patient Radiation Exposure During Fluoro-Assisted Direct Anterior Approach Total Hip Arthroplasty. 
  • Pediatric providers and radiology examinations: knowledge and comfort levels regarding ionizing radiation and potential complications of imaging. 
  • Perspective on Ionizing Radiation Exposure to Neurosurgery Residents in the Modern Era. 
  • Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. 
  • Population models for the health effects of ionizing radiation. 
  • Postradiation sarcoma: case report and review of the potential complications of therapeutic ionizing radiation. 
  • Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2. 
  • Public health. Genomics and medicine at a crossroads in Chernobyl. 
  • Radiation exposure in gastroenterology: improving patient and staff protection. 
  • Radiation risk to children from computed tomography. 
  • Radiation-induced genomic instability: radiation quality and dose response. 
  • Radiologic Aspects of the Diagnosis of Pulmonary Embolism in Pregnancy. 
  • Reconsidering the Value of Gonadal Shielding During Abdominal/Pelvic Radiography. 
  • Reply to Dr. Andronikou: Holding on to informed use of diagnostic imaging using ionizing radiation. 
  • Should we obtain informed consent for examinations that expose patients to radiation? 
  • The antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation. 
  • The associations of adolescent cigarette smoking, alcoholic beverage consumption, environmental tobacco smoke, and ionizing radiation with subsequent breast cancer risk (United States). 
  • The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. 
  • The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. 
  • Topoisomerase I is essential in Cryptococcus neoformans: role In pathobiology and as an antifungal target. 
  • Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. 
  • Using genetically engineered mice for radiation research. 
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  Keywords of People

  • Doan, Phuong Linh, Assistant Professor of Medicine, Duke Cancer Institute
  • Moorman, Patricia Gripka, Professor in Family Medicine and Community Health, Duke Cancer Institute