Radioimmunoassay

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  Subject Areas on Research

  • 8-hydroxy-2-(di-n-propylamino)tetralin-responsive 5-hydroxytryptamine4-like receptor expressed in bovine pulmonary artery smooth muscle cells. 
  • A Phase I clinical trial of immunotherapy with interferon-gamma gene-modified autologous melanoma cells: monitoring the humoral immune response. 
  • A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia. 
  • A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope. 
  • A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells. 
  • A radioimmunoassay for the estimation of serum dehydroepiandrosterone sulphate in normal and pathological sera. 
  • Abnormal amniotic fetal antigen 2 concentrations in trisomy 18 and trisomy 21. 
  • Activin A and follistatin are dynamically regulated during human pregnancy. 
  • Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis. 
  • Adiponectin changes in relation to the macronutrient composition of a weight-loss diet. 
  • Alterations in the hypothalamic-pituitary-adrenal axis in a proposed animal model of depression with genetic muscarinic supersensitivity. 
  • Analysis of implantation in assisted reproduction through the use of serial human chorionic gonadotropin measurements. 
  • Angiotensin converting enzyme in renal ontogeny: hypothesis for multiple roles. 
  • Annual changes in serum concentrations of prolactin in captive male black bears (Ursus americanus). 
  • Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain. 
  • Antidouble stranded DNA antibody assays in systemic lupus erythematosus: correlations of longitudinal antibody measurements. 
  • Antigenic activity of human urothelial tissue. 
  • Antiserum to diphenylhydantoin: preparation and characterization. 
  • Association between low levels of 1,25-dihydroxyvitamin D and breast cancer risk. 
  • Atrial natriuretic peptide increases urodilatin in the circulation. 
  • Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells. 
  • Biochemical changes in leukocytes in response to chemoattractants. 
  • Biological monitoring for occupational cadmium exposure: the urinary metallothionein. 
  • C-terminal region of human T cell lymphotropic virus type I (HTLVI) p19 core protein is immunogenic in humans and contains an HTLVI-specific epitope. 
  • CFTR: development of high- affinity antibodies and localization in sweat gland. 
  • CSF corticotropin-releasing factor-like immunoactivity in chronic pain patients with and without major depression. 
  • Caffeine in plasma and saliva by a radioimmunoassay procedure. 
  • Calmodulin overexpression causes Ca(2+)-dependent apoptosis of pancreatic beta cells, which can be prevented by inhibition of nitric oxide synthase. 
  • Calmodulin. Development and application of a sensitive radioimmunoassay. 
  • Calmodulin: properties, intracellular localization, and multiple roles in cell regulation. 
  • Carcinoma of the pancreas. Therapeutic efficacy as defined by a serodiagnostic test utilizing a monoclonal antibody. 
  • Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. 
  • Characterization of a monoclonal antibody specific for human active renin. 
  • Characterization of the immune response to the major glycoprotein (gp 71) of Friend leukemia virus. I. Response in BALB/c mice. 
  • Characterization of the immune response to the major glycoprotein (gp71) of Friend leukemia virus. II. Response in C57BL/6 mice. 
  • Characterization of the immune response to the major glycoprotein (gp71) of Friend leukemia virus. III. Influence on endogenous MuLV-mediated pathogenesis. 
  • Chronic cocaine administration sensitizes behavioral but not neuroendocrine responses. 
  • Circulating IgA immune complexes in patients with psoriasis. 
  • Clinical and immunologic features of selective IgA deficiency. 
  • Clinical studies on the radioimmunodetection of tumors containing alpha-fetoprotein. 
  • Combined antibody-high-performance liquid chromatography approach to assess prohormone processing. 
  • Constitutive production of macrophage colony-stimulating factor and interleukin-6 by human ovarian surface epithelial cells. 
  • Corticotropin releasing factor stimulates growth hormone secretion in neonatal rats. 
  • Cortisol responses to emotional stress in men: association with a functional polymorphism in the 5HTR2C gene. 
  • Creatine kinase brain isoenzyme: relationship of cerebrospinal fluid concentration to the neurologic condition of newborns and cellular localization in the human brain. 
  • Deficient red-cell spectrin in severe, recessively inherited spherocytosis. 
  • Delta-opioid-receptor activation by [D-Pen2,D-Pen5]enkephalin and morphine inhibits substance P release from trigeminal nucleus slices. 
  • Demonstration of a relation between urinary digoxin-like immunoreactive substance and cardiac performance. 
  • Demonstration of complex antigenic heterogeneity in a human glioma cell line and eight derived clones by specific monoclonal antibodies. 
  • Detection in human serum by radioimmunoassay of histidyl-proline diketopiperazine, a metabolite of thyrotropin-releasing hormone. 
  • Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) in serum and ascites of patients with adenocarcinoma. 
  • Detection of illicit substance use among persons with schizophrenia by radioimmunoassay of hair. 
  • Detection of oncornavirus antigenic activity in human urothelial tissues. 
  • Development of a radioimmunoassay for fetal antigen 2. 
  • Dietary regulation of glucose-dependent insulinotropic peptide (GIP) gene expression in rat small intestine. 
  • Differences in the estrogen content of breast adipose tissue in women by menopausal status and hormone use. 
  • Different ontogenetic patterns of testosterone production reflect divergent male reproductive strategies in chimpanzees and bonobos. 
  • Dioxin-like activity and maternal thyroid hormone levels in second trimester maternal serum. 
  • Disialoganglioside GD2 in human neuroectodermal tumor cell lines and gliomas. 
  • Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations. 
  • Distribution and localization of a novel cholecystokinin-releasing factor in the rat gastrointestinal tract. 
  • Double antibody radioimmunoassay for monitoring metastatic breast cancer. 
  • Early diagnosis and treatment of medullary thyroid carcinoma. 
  • Effect of acute exercise on plasma neurotensin levels. 
  • Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe. 
  • Effect of fatty acids on insulin release: role of chain length and degree of unsaturation. 
  • Effect of ingested nutrients on the release of thrittene into the human circulation. 
  • Effect of interferon-gamma and human alpha 2-macroglobulin on peritoneal macrophage morphology and Ia antigen expression. 
  • Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK. 
  • Effects of atrial natriuretic peptide on rat ovarian granulosa cell steroidogenesis in vitro. 
  • Effects of cadmium ingestion and food restriction on energy metabolism and tissue metal concentrations in mallard ducks (Anas platyrhynchos). 
  • Effects of cytokines on porcine granulosa cell steroidogenesis in vitro. 
  • Effects of fasting, refeeding, and intraluminal triglyceride on proglucagon expression in jejunum and ileum. 
  • Effects of high-dose cancer chemotherapy on the absorption of digoxin in two different formulations. 
  • Elevated beta-cell calmodulin produces a unique insulin secretory defect in transgenic mice. 
  • Elevated serum secretory immunoglobulin A levels in patients with head and neck carcinoma. 
  • Elevation of multiple serum markers in patients with stage I ovarian cancer. 
  • Endocrine correlates of pregnancy in the ring-tailed lemur (Lemur catta): implications for the masculinization of daughters. 
  • Endothelial cell surface expression and binding of factor VIII/von Willebrand factor. 
  • Endothelial renin-angiotensin pathway. Adrenergic regulation of angiotensin secretion. 
  • Enhanced renal leukotriene production in murine lupus: role of lipoxygenase metabolites. 
  • Evaluation of a role for 1,25-dihydroxyvitamin D3 in the pathogenesis and treatment of X-linked hypophosphatemic rickets and osteomalacia. 
  • Evidence that ship noise increases stress in right whales. 
  • Experimental cryopreservation and autotransplantation of parathyroid glands: technique and demonstration of function. 
  • Expression and production of interleukin-10 by human trophoblast: relationship to pregnancy immunotolerance. 
  • Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas. 
  • Falsely elevated urinary excretion of catecholamines and metanephrines in patients receiving labetalol therapy. 
  • Free triiodothyronine (T3) and thyroxine (T4) in a group of unipolar depressed patients and normal subjects. 
  • GD3 expression by cultured human tumor cells of neuroectodermal origin. 
  • Gastrin-releasing peptide gene expression in developing, hyperplastic, and neoplastic human thyroid C-cells. 
  • Generation of human IgG, IgA, and IgM anti-melanoma monoclonal antibodies utilizing lymphocytes of an actively immunized melanoma patient. 
  • Ghrelin stimulation of growth hormone isoforms: parallel secretion of total and 20-kDa growth hormone and relation to insulin sensitivity in healthy humans. 
  • Glioma-associated antigens defined by monoclonal antibodies against an avian sarcoma virus-induced rat astrocytoma. 
  • Glycemic response to stress is altered in euglycemic Pima Indians. 
  • Growth retardation in the Lesch-Nyhan syndrome. 
  • Hepatic clearance and metabolism in the rat of a human breast cancer associated glycoprotein (GCDFP-15). 
  • Hepatitis B antigen in saliva, urine, and stool. 
  • Heterogeneity of somatostatin like immunoreactivity (SLI) in extracts of porcine, canine and human pancreas. 
  • Human erythrocyte acetylcholinesterase bears the Yta blood group antigen and is reduced or absent in the Yt(a-b-) phenotype. 
  • Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein. 
  • Hyperglycemia induces insulin resistance on angiotensinogen gene expression in diabetic rat kidney proximal tubular cells. 
  • Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties. 
  • IgA-containing circulating immune complexes in dermatitis herpetiformis, Henoch-Schönlein purpura, systemic lupus erythematosus and other diseases. 
  • IgA-containing circulating immune complexes in patients with igA nephropathy. 
  • IgA-containing immune complexes in patients with psoriatic arthritis. 
  • Immunoblot analyses of Candida albicans-associated antigens and antibodies in human sera. 
  • Immunodiagnosis of human malignancy. 
  • Immunological properties of avian oncornavirus polypeptides. 
  • Immunoradiometric assay for examination and quantitation of Brucella abortus-specific antibodies reactive with the antigen(s) used in the indirect hemolysis test. 
  • Implantation and pregnancy rates in relation to oestradiol and progesterone profiles in cycles with and without the use of gonadotrophin-releasing hormone agonist suppression. 
  • In vitro synthesis of steroids by a feminising adrenocortical carcinoma: effect of prolactin and other protein hormones. 
  • In vivo antigenic modification of tumor cells. I. Introduction of murine leukemia virus antigens on non-virus-producing murine sarcomas. 
  • Increased serum levels of macrophage colony-stimulating factor in ovarian cancer. 
  • Induction of specific cytochrome P-450 isozymes by methylenedioxyphenyl compounds and antagonism by 3-methylcholanthrene. 
  • Influence of continuous infusion of citrate on responses of immunoreactive parathyroid hormone, calcium and magnesium components, and other electrolytes in normal adults during plateletapheresis. 
  • Intact parathyroid hormone overestimates the presence and severity of parathyroid-mediated osseous abnormalities in uremia. 
  • Interactions of calmodulin with coated vesicles from brain. 
  • Interleukin-6: effects on and production by rat granulosa cells in vitro. 
  • Intracerebroventricular infusion of bombesin modulates GIP secretion in conscious dogs. 
  • Intracytoplasmic sperm injection: achievement of high pregnancy rates in couples with severe male factor infertility is dependent primarily upon female and not male factors. 
  • Isolated hormone receptors: physiologic and clinical implications. 
  • Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis. 
  • Isolation of the JMH antigen on a novel phosphatidylinositol-linked human membrane protein. 
  • Life-history correlates of steroid concentrations in wild peripartum baboons. 
  • Luteal phase serum estradiol and progesterone in in vitro fertilization. 
  • Mapping of homologous, amino-terminal neutralizing regions of human T-cell lymphotropic virus type I and II gp46 envelope glycoproteins. 
  • Measles virus nucleocapsids: large-scale purification and use in radioimmunoassays. 
  • Measurement of diphenylhydantoin in 0.1-ml plasma samples: gas chromatography and radioimmunoassay compared. 
  • Measuring fecal testosterone in females and fecal estrogens in males: comparison of RIA and LC/MS/MS methods for wild baboons (Papio cynocephalus). 
  • Melanoma patient antibody responses to melanoma tumor-associated antigens defined by murine monoclonal antibodies. 
  • Melatonin regulates energy balance and attenuates fever in Siberian hamsters. 
  • Mitosis is required for production of murine leukemia virus and structural proteins during de novo infection. 
  • Monoclonal antibodies reactive with epitopes restricted to glial fibrillary acidic proteins of several species. 
  • Morphine produces a multiphasic effect on the release of substance P from rat trigeminal nucleus slices by activating different opioid receptor subtypes. 
  • Morphologic and immunologic studies of human prostatic carcinoma. 
  • Multiphasic effect of morphine on the release of substance P from rat trigeminal nucleus slices. 
  • Multiple assay characterization of murine monoclonal antimelanoma antibodies. 
  • Nocturnal and early morning secretion of ACTH and cortisol in humans. 
  • OVX1 radioimmunoassay complements CA-125 for predicting the presence of residual ovarian carcinoma at second-look surgical surveillance procedures. 
  • Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. 
  • Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions. 
  • On the measurement of cholecystokinin. 
  • Oncornavirus-like protein expression in human prostatic tissue. 
  • Parotid and whole saliva in the prediction of serum total and free phenytoin concentrations. 
  • Partial deficiency of erythrocyte spectrin in hereditary spherocytosis. 
  • Partial purification and characterization of a murine glioma-associated antigen defined by syngeneic rat monoclonal antibodies. 
  • Peptide YY: metabolism and effect on pancreatic secretion in dogs. 
  • Pharmacokinetics and biochemical efficacy of pirmagrel, a thromboxane synthase inhibitor, in renal allograft recipients. 
  • Pharmacokinetics of pentobarbital enantiomers as determined by enantioselective radioimmunoassay after administration of racemate to humans and rabbits. 
  • Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc. 
  • Phenytoin and phenobarbital concentrations in saliva and plasma measured by radioimmunoassay. 
  • Photoperiod alters the time course of brain cyclooxygenase-2 expression in Siberian hamsters. 
  • Physiologic role for enhanced renal thromboxane production in murine lupus nephritis. 
  • Plasma concentrations of 11-deoxycorticosterone in women during the menstrual cycle. 
  • Plasma dexamethasone concentrations and the dexamethasone suppression test. 
  • Polypeptides of mammalian oncornaviruses. II Characterization of murine leukemia virus polypeptide (p 15) bearing interspecies reactivity. 
  • Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. 
  • Primary hyperparathyroidism: a new experimental animal model. 
  • Prostacyclin protects against elevated blood pressure and cardiac fibrosis. 
  • Prostate and transitional cell carcinoma: radioimmunoassay of viral tumor-associated antigens. 
  • Radioimmunoassay for terfenadine in human plasma. 
  • Radioimmunoassay of calmodulin. 
  • Radioimmunoassay of plasma estradiol during the breeding cycle of ring doves (Streptopelia risoria). 
  • Radioimmunoassays for cannabinoids. 
  • Radiolocalization of human mammary tumors in athymic mice by a monoclonal antibody. 
  • Radiommunoassay of delta9-tetrahydrocannabinol. 
  • Radioreceptor assay of adrenocorticotropic hormone: new approach to assay of polypeptide hormones in plasma. 
  • Relationship of the serotonin transporter with prolactin response to meta-chlorophenylpiperazine in cocaine dependence. 
  • Release of corticotropin-releasing factor from rat brain regions in vitro. 
  • Response to hepatitis B immunization in children with hemophilia: relationship to infection with human immunodeficiency virus type 1. 
  • Role of carbohydrate in determining the immunochemical properties of the major glycoprotein (gp71) of Friend murine leukemia virus. 
  • Role of gonadotropin-releasing hormone pulse frequency in differential regulation of gonadotropins in the gilt. 
  • Seasonal variation of salivary testosterone in men, normally cycling women, and women using hormonal contraceptives. 
  • Sensitive and specific detection of the 4B5 antigen in bronchial lavage specimens from patients with primary bronchogenic carcinoma. 
  • Sequential adsorption analysis of antibodies to neuroectodermal cells by an indirect quantitative method. 
  • Serological and biochemical characterization of monoclonal antibodies against red cell markers related to expression of Lutheran blood group antigens. 
  • Serum IgD concentrations in normal infants, children, and adults and in patients with elevated IgE. 
  • Serum angiotensin converting enzyme activity in evaluation of patients with liver disease. 
  • Serum dehydroepiandrosterone (DHA) and sulphate (DHAS) after acute growth hormone therapy. 
  • Sex hormone levels and gonadotrophin release in the polycystic ovary syndrome. 
  • Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling. 
  • Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function. 
  • Solid-phase microtiter radioimmunoassay blocking test for detection of antibodies to Escherichia coli heat-labile enterotoxin. 
  • Soluble interleukin-2 receptor alpha is elevated in sera of patients with benign ovarian neoplasms and epithelial ovarian cancer. 
  • Species differences in alpha 2-adrenergic regulation of platelet adenylate cyclase. 
  • Specific and non-specific measurements of tissue angiotensin II cascade members. 
  • Spectrophotometry of cerebral cytochrome a, a3 in bloodless rats. 
  • Stress-induced changes in the expression of monocytic beta2-integrins: the impact of arousal of negative affect and adrenergic responses to the Anger Recall Interview. 
  • Suppression and flare regimens of gonadotropin-releasing hormone agonist. Use in women with different basal gonadotropin values in an in vitro fertilization program. 
  • Synergistic effect of dexamethasone and isoproterenol on the expression of angiotensinogen in immortalized rat proximal tubular cells. 
  • The effect of neonatal exposure to DES and o,p'-DDT on pituitary responsiveness to GnRH in adult castrated rats. 
  • The effect of serial dilution error on calibration inference in immunoassay. 
  • The effect of variance function estimation on nonlinear calibration inference in immunoassay data. 
  • The hypogonadotropic state of the prepubertal male rhesus monkey (Macaca mulatta) is not associated with a decrease in hypothalamic gonadotropin-releasing hormone content. 
  • The intestinal lymph fistula model--a novel approach to study ghrelin secretion. 
  • The measurement of morphine in the hair of heroin abusers. 
  • The prediction and/or detection of ovulation by means of urinary steroid assays. 
  • The preparation and properties of an antiserum for the radioimmunoassay of serum conjugated cholic acid. 
  • The regulation of proenkephalin expression in a distinct population of glial cells. 
  • The responses of atrial natriuretic factor concentrations to acute volume changes in conscious rats. 
  • The suppressive effect of a synthetic retroviral peptide on the human IFN gamma production is abrogated by the combined stimulation with IL-1 and IL-2. 
  • The typing of fetal antigen 2 in human amniotic fluid. 
  • The use of a urinary estrone conjugates assay for detection of optimal mating time in the cynomolgus macaque (Macaca fascicularis). 
  • The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. 
  • Theophylline radioimmunoassay: synthesis of antigen and characterization of antiserum. 
  • Three peptides from the atrial natriuretic factor prohormone amino terminus lower blood pressure and produce diuresis, natriuresis, and/or kaliuresis in humans. 
  • Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation. 
  • Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism. 
  • Toxicity of methoxyacetic acid in cultured human luteal cells. 
  • Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): effect of repeated administration. 
  • Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with luteinizing hormone releasing hormone. 
  • Transforming growth factor-beta inhibits prostaglandin production in amnion and A431 cells. 
  • Transmission of HIV by antigen presenting cells during T-cell activation: prevention by 3'-azido-3'-deoxythymidine. 
  • Urinary digoxin-like immunoreactive substance in pregnancy. Relation to urinary electrolytes. 
  • Utility of fluoroimmunoassay in detecting luteinizing hormone surges in spontaneous and human menopausal gonadotropin-stimulated menstrual cycles. 
  • Warfarin enantiomer disposition: determination by stereoselective radioimmunoassay. 
  • [Synthesis of human proinsulin in Escherichia coli cells]. 
  • pN collagen type III within tendon grafts used for anterior cruciate ligament reconstruction. 
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  Keywords of People

  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bradford, Daniel William, Professor of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Community Psychiatry
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor Emeritus of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology