Receptors, Adrenergic

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  Subject Areas on Research

  • (3H)-Propranolol binding sites in myocardial membranes: nonidentity with beta adrenergic receptors. 
  • 125I-labeled p-azidobenzylcarazolol, a photoaffinity label for the beta-adrenergic receptor. Characterization of the ligand and photoaffinity labeling of beta 1- and beta 2-adrenergic receptors. 
  • A desensitized state of the beta adrenergic receptor not associated with high-affinity agonist occupancy. 
  • A fraction of the ventricular myocardium that has the specificity of the cardiac beta-adrenergic receptor. 
  • A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes. 
  • A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data. 
  • A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. 
  • Activation and desensitization of beta-adrenergic receptor-coupled GTPase and adenylate cyclase of frog and turkey erythrocyte membranes. 
  • Activation of adenylate cyclase by beta-adrenergic receptors: investigation of rate limiting steps by simultaneous assay of high affinity agonist binding and GDP release. 
  • Adenylate cyclase-coupled beta adrenergic receptors effect of membrane lipid-perturbing agents on receptor binding and enzyme stimulation by catecholamines. 
  • Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization. 
  • Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding. 
  • Adrenergic receptors in the heart. 
  • Adrenergic receptors. 
  • Adrenergic receptors. 
  • Adrenergic receptors. Models for regulation of signal transduction processes. 
  • Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins. 
  • Adrenergic receptors: biochemistry, regulation, molecular mechanism, and clinical implications. 
  • Adrenergic receptors: molecular mechanisms of clinically relevant regulation. 
  • Adrenergic receptors: recent insights into their mechanism of activation and desensitization. 
  • Adrenoceptors, uncoupling proteins, and energy expenditure. 
  • Affinity chromatography of adrenergic receptors and binding proteins. 
  • Affinity chromatography of human platelet alpha 2-adrenergic receptors. 
  • Affinity chromatography of the beta-adrenergic receptor and characterization of antibodies raised against purified receptor preparations. 
  • Affinity chromatography of the beta-adrenergic receptor. 
  • Age-associated loss of beta adrenergic receptors from human lymphocytes in vivo [proceedings]. 
  • Agonist interactions with alpha-adrenergic receptors. 
  • Agonist versus antagonist binding to alpha-adrenergic receptors. 
  • Agonist-induced increase in apparent beta-adrenergic receptor size. 
  • Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system. 
  • Agonist-promoted high affinity state of the beta-adrenergic receptor in human neutrophils: modulation by corticosteroids. 
  • Agonist-specific alterations in receptor binding affinity associated with solubilization of turkey erythrocyte membrane beta adrenergic receptors. 
  • Agonist-specific effects of guanine nucleotides on alpha-adrenergic receptors in human platelets. 
  • Agonist-specific effects of monovalent and divalent cations on adenylate cyclase-coupled alpha adrenergic receptors in rabbit platelets. 
  • Alpha 2 adrenergic receptors are located prejunctionally in the Auerbach's plexus of the guinea pig small intestine: direct demonstration by radioligand binding. 
  • Alpha adrenergic receptor subtypes in rabbit uterus: mediation of myometrial contraction and regulation by estrogens. 
  • Alpha-adrenergic receptor identification by (3H)dihydroergocryptine binding. 
  • Alpha-adrenergic receptor subtypes. 
  • Alpha-adrenergic receptor subtypes: quantitative assessment by ligand binding. 
  • Alpha-adrenergic receptors in liver membranes: delineation with subtype selective radioligands. 
  • Alpha-adrenergic receptors in rat myocardium. Identification by binding of [3H]dihydroergocryptine. 
  • Alternative explanation for the apparent "two-step" binding kinetics of high-affinity racemic antagonist radioligands. 
  • An assay for alpha-adrenergic receptor subtypes using [3H]dihydroergocryptine. 
  • Anomalous equilibrium binding properties of high-affinity racemic radioligands. 
  • Antibodies raised against purified beta-adrenergic receptors specifically bind beta-adrenergic ligands. 
  • Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain. 
  • Autonomic mechanisms of training bradycardia: beta-adrenergic receptors in humans. 
  • Behavioral and prolactin responses to 5-hydroxytryptophan in rats treated during development with 5,7-dihydroxytryptamine. 
  • Benzodiazepine and beta-adrenergic receptor ligands independently stimulate phospholipid methylation. 
  • Beta adrenergic and muscarinic cholinergic receptors in canine myocardium. Effects of ischemia. 
  • Beta adrenergic receptors in lymphocyte subpopulations. 
  • Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism. 
  • Beta-Adrenergic receptors: solubilization of (-)(3H)alprenolol binding sites from frog erythrocyte membranes. 
  • Beta-adrenergic receptor binding: synaptic localization in rat brain. 
  • Beta-adrenergic receptors: evidence for negative cooperativity. 
  • Beta-adrenergic receptors: recognition and regulation. 
  • Beta-adrenoreceptors determine affinity but not intrinsic activity of adenylate cyclase stimulants. 
  • Binding of catecholamines to receptors in cultured myocardial cells. 
  • Biochemical characterization of the adrenergic receptors: affinity labeling, purification, and reconstitution studies. 
  • Biochemical characterization of the beta-adrenergic receptor of the frog erythrocyte. 
  • Cardiac function in genetically engineered mice with altered adrenergic receptor signaling. 
  • Cardiovascular hemodynamics during stress in premenopausal versus postmenopausal women. 
  • Catecholamine binding to the beta-adrenergic receptor. 
  • Catecholamine receptors: structure, function, and regulation. 
  • Catecholamine-induced desensitization in turkey erythrocytes: cAMP mediated impairment of high affinity agonist binding without alteration in receptor number. 
  • Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. 
  • Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling. 
  • Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites. 
  • Chronic estrogen treatment decreases beta-adrenergic responses in rat cerebral cortex. 
  • Chronic guanethidine treatment increases cardiac beta-adrenergic receptors. 
  • Ciba-Geigy award for outstanding research. Regulation of adrenergic receptor function by phosphorylation. 
  • Clinical physiology of adrenergic receptor regulation. 
  • Commentary. Molecular pharmacology of beta-adrenergic receptors--a status report. 
  • Comparison of specificity of agonist and antagonist radioligand binding to beta adrenergic receptors. 
  • Coronary and systemic hemodynamic effects of dopamine in the awake dog. 
  • Correlation of beta-adrenergic receptor-stimulated [3H]GDP release and adenylate cyclase activation. Differences between frog and turkey erythrocyte membranes. 
  • Corticosteroid-induced differential regulation of beta-adrenergic receptors in circulating human polymorphonuclear leukocytes and mononuclear leukocytes. 
  • Decreased beta-adrenergic responses in the female rat brain are eliminated by ovariectomy: correlation of [3H]dihydroalprenolol binding and catecholamine stimulated cyclic AMP levels. 
  • Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides. 
  • Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles. 
  • Desvenlafaxine succinate: a newer antidepressant for the treatment of depression and somatic symptoms. 
  • Determination of subtype selectivity of alpha-adrenergic antagonists: comparison of selective and nonselective radioligands. 
  • Development of adrenergic receptor binding sites in brain regions of the neonatal rat: effects of prenatal or postnatal exposure to methylmercury. 
  • Development of alpha-noradrenergic and Dopaminergic receptor systems depends on maturation of their presynaptic nerve terminals in the rat brain. 
  • Development of the linkage of beta-adrenergic receptors to cardiac hypertrophy and heart rate control: neonatal sympathectomy with 6-hydroxydopamine. 
  • Differences between agonist and antagonist binding following beta-adrenergic receptor desensitization. 
  • Different sedimentation properties of agonist- and antagonist-labelled platelet alpha 2 adrenergic receptors. 
  • Differential effects of GTP on the coupling of beta-adrenergic receptors to adenylate cyclase from frog and turkey erythrocytes. Application of new methods for the analysis of receptor-effector coupling. 
  • Differential effects of cholera toxin on guanine nucleotide regulation of beta-adrenergic agonist high affinity binding and adenylate cyclase activation in frog erythrocyte membranes. 
  • Differential regulation of the alpha 2-adrenergic receptor by Na+ and guanine nucleotides. 
  • Differentiation of hemodynamic, humoral and metabolic responses to beta 1- and beta 2-adrenergic stimulation in man using atenolol and propranolol. 
  • Dihydroergocryptine binding and alpha-adrenoreceptors in smooth muscle. 
  • Direct binding studies of adrenergic receptors: biochemical, physiologic, and clinical implications. 
  • Direct identification and characterisation of beta-adrenergic receptors in rat brain. 
  • Direct studies of beta-adrenergic receptors intact frog erythrocytes. 
  • Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes. 
  • Ectopic beta-adrenergic receptor binding sites. possible molecular basis of aberrant catecholamine responsiveness of an adrenocortical tumor adenylate cyclase. 
  • Editorial: Selectivity in beta-adrenergic responses: clinical implications. 
  • Effect of the monoamine oxidase inhibitors clorgyline and pargyline on the hyperphagia of obese mice. 
  • Effects of local anesthetics on guanyl nucleotide modulation of the catecholamine-sensitive adenylate cyclase system and on beta-adrenergic receptors. 
  • Elevated beta-adrenergic receptor number after chronic propranolol treatment. 
  • Enhanced receptor-cyclase coupling and augmented catecholamine-stimulated lipolysis in exercising rats. 
  • Ethnicity, gender, and age effects on adrenoceptors and physiological responses to emotional stress. 
  • Evidence that a beta-adrenergic receptor-associated guanine nucleotide regulatory protein conveys guanosine 5'-O-(3-thiotriphosphate)- dependent adenylate cyclase activity. 
  • Fetal cocaine exposure causes persistent noradrenergic hyperactivity in rat brain regions: effects on neurotransmitter turnover and receptors. 
  • Functional consequences of altering myocardial adrenergic receptor signaling. 
  • Functional integrity of desensitized beta-adrenergic receptors. 
  • Functional selectivity in adrenergic and angiotensin signaling systems. 
  • Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution. 
  • Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. 
  • Guanine nucleotides and alpha 1 adrenergic receptors in the heart. 
  • Hepatic alpha-adrenergic receptors. Identification and subcellular localization using [3H]dihydroergocryptine. 
  • Hepatic fibrogenesis requires sympathetic neurotransmitters. 
  • Heterogeneity of adenylate cyclase-coupled beta-adrenergic receptors. 
  • Heterogeneity of radioligand binding to alpha-adrenergic receptors. Analysis of guanine nucleotide regulation of agonist binding in relation to receptor subtypes. 
  • Hormonal inhibition of adenylate cyclase. alpha 2 Adrenergic receptors promote release of [3H]guanylylimidodiphosphate from platelet membranes. 
  • Hormone-sensitive adenylate cyclase. Delineation of a trypsin-sensitive site in the pathway of receptor-mediated inhibition. 
  • Human cardiac beta-adrenergic receptors: subtype heterogeneity delineated by direct radioligand binding. 
  • Hypothermia: role of alpha 1- and alpha 2-noradrenergic receptors in the hypothalamus of the cat. 
  • Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes. 
  • I. Pharmacological studies with derivatives of 2-aminotetralin, benzhydro[f]quinoline and clonidine suggest a pharmacological identity between peripheral and central alpha-2 adrenoceptors. 
  • II. Pharmacological studies with derivatives of 2-aminotetralin, benzhydro[f]quinoline, benzhydro[g]quinoline, apomorphine and clonidine suggest a pharmacological dissimilarity between peripheral presynaptic dopamine receptors and alpha-2 adrenoceptors. 
  • Identification and characterization of adrenergic receptors and catecholamine-stimulated adenylate cyclase in hog pial membranes. 
  • Identification and regulation of alpha- and beta-adrenergic receptors. 
  • Identification and regulation of beta-adrenergic receptors. 
  • Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists. 
  • Identification of alpha-adrenergic receptors in human platelets by [3H]dihydroergocryptine binding. 
  • Identification of alpha-adrenergic receptors in uterine smooth muscle membranes by [3H]dihydroergocryptine binding. 
  • Identification of beta adrenergic receptors in rat hypothalamus. 
  • Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding. 
  • Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding. 
  • Identification of the cardiac beta-adrenergic receptor protein: solubilization and purification by affinity chromatography. 
  • In situ hybridization of adrenergic receptor mRNA in brain. 
  • In vitro desensitization of beta adrenergic receptors in human neutrophils. Attenuation by corticosteroids. 
  • Inhibition of epinephrine-induced vasospasm with adrenoreceptor blockade in the rat cremaster muscle. 
  • Interaction of signals influencing renin release. 
  • Interactions of agonists with platelet alpha 2-adrenergic receptors. 
  • International Union of Pharmacology nomenclature of adrenoceptors. 
  • Isolated beta-adrenergic binding sites: a potential assay vehicle for catecholamines. 
  • Isolated hormone receptors: physiologic and clinical implications. 
  • Isolation and characterization of the beta-adrenergic receptor of frog erythrocytes and development of potential affinity ligands. 
  • Janus molecule I: dichotomous effects of COMT in neuropathic vs nociceptive pain modalities. 
  • Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol. 
  • Loss of beta-adrenergic receptor-guanine nucleotide regulatory protein interactions accompanies decline in catecholamine responsiveness of adenylate cyclase in maturing rat erythrocytes. 
  • Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: implications for sudden infant death syndrome. 
  • Macromolecular beta-adrenergic antagonists discriminating between receptor and antibody. 
  • Magnesium dependence of agonist binding to adenylate cyclase-coupled hormone receptors. 
  • Mammalian beta-adrenergic receptors. Structural differences in beta 1 and beta 2 subtypes revealed by peptide maps. 
  • Maternal methadone administration: deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of 33Pi incorporation into phospholipids in vivo. 
  • Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase. 
  • Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors. 
  • Modulation of hepatic adrenergic receptor ontogeny by thyroid hormone. 
  • Molecular and regulatory properties of adrenergic receptors. 
  • Molecular biology of adrenergic receptors in the rat and frog central nervous system. 
  • Molecular characterization of the beta-adrenergic receptor of frog erythrocytes. 
  • Molecular mechanisms of activation and desensitization of adenylate cyclase coupled beta-adrenergic receptors. 
  • Molecular mechanisms of beta-adrenergic receptor desensitization. 
  • Molecular pharmacology of adenylate cyclase-coupled alpha- and beta-adrenergic receptors. 
  • Molecular pharmacology of alpha adrenergic receptors: utilization of [3H]dihydroergocryptine binding in the study of pharmacological receptor alterations. 
  • Multiple effects of N, N' dicyclohexyl carbodiimide on the beta-adrenergic receptor--adenylate cyclase system in frog erythrocytes. 
  • Multiple reactive sulfhydryl groups modulate the function of adenylate cyclase coupled beta-adrenergic receptors. 
  • Myocardial beta-adrenergic receptors from adrenalectomized rats: impaired formation of high-affinity agonist-receptor complexes. 
  • Negative cooperativity among beta-adrenergic receptors in frog erythrocyte membranes. 
  • Neonatal rat pinealocytes: typical and atypical characteristics of [125I]iodohydroxybenzylpindolol binding and adenosine 3',5'-monophosphate accumulation. 
  • Network integration of the adrenergic system in cardiac hypertrophy. 
  • Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase. 
  • Neurobiological mechanisms in generalized anxiety disorder. 
  • New developments in cardiovascular adrenergic receptor pharmacology: molecular mechanisms and clinical relevance. 
  • Norepinephrine: dissociation of -receptor binding from adenylate cyclase activation in solubilized myocardium. 
  • Ontogeny of rat hepatic adrenoceptors. 
  • Parallel modulation of catecholamine activation of adenylate cyclase and formation of the high-affinity agonist.receptor complex in turkey erythrocyte membranes by temperature and cis-vaccenic acid. 
  • Peripheral alpha-adrenergic receptor subtypes. 
  • Peripheral vascular effects of a new dopamine analog: 5-6-dihydroxy-2-methylaminotetralin (M-8). 
  • Pharmacological characterizations of adrenergic receptors in human adipocytes. 
  • Pharmacological evaluation of central adrenergic involvement in chlordecone-induced hypothermia. 
  • Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes. 
  • Photoaffinity labeling of the beta-adrenergic receptor. 
  • Photoaffinity labelling of mammalian beta-adrenergic receptors: metal-dependent proteolysis explains apparent heterogeneity. 
  • Physical conditioning and membrane receptors for cardioregulatory hormones. 
  • Physiological receptors as physicochemical entities. 
  • Pineal beta adrenergic receptor: correlation of binding of 3H-l-alprenolol with stimulation of adenylate cyclase. 
  • Platelet alpha 2-adrenergic receptors in schizophrenic patients before and after phenothiazine treatment. 
  • Polymorphonuclear leukocyte function in psoriasis: chemotaxis, chemokinesis, beta-adrenergic receptors, and proteolytic enzymes of polymorphonuclear leukocytes in the peripheral blood from psoriatic patients. 
  • Postnatal nutritional status influences development of cardiac adrenergic receptor binding sites. 
  • Potent beta-adrenergic antagonist possessing chemically reactive group. 
  • Potential mechanisms of action of atypical antipsychotic medications in treatment-resistant depression and anxiety. 
  • Preferential uncoupling by manganese of alpha adrenergic receptor mediated inhibition of adenylate cyclase in human platelets. 
  • Prenatal nicotine effects on memory in rats: pharmacological and behavioral challenges. 
  • Production of adrenergic receptors in yeast. 
  • Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit. 
  • Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a computerized model fitting technique. 
  • Race, common genetic variation, and therapeutic response disparities in heart failure. 
  • Radioligand binding studies of adrenergic receptors: new insights into molecular and physiological regulation. 
  • Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. 
  • Reduced beta-adrenergic receptor concentrations in ageing man. 
  • Regulation of G protein-coupled receptor signaling by scaffold proteins. 
  • Regulation of adenylate cyclase coupled beta-adrenergic receptors by beta-adrenergic catecholamines. 
  • Regulation of adenylate cyclase coupled beta-adrenergic receptors. 
  • Regulation of adenylate cyclase-coupled beta adrenergic receptor binding sites by beta adrenergic catecholamines in vitro. 
  • Regulation of adrenergic receptor function by phosphorylation. 
  • Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. 
  • Regulation of beta adrenergic receptors in isolated frog erythrocyte plasma membranes. 
  • Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides. 
  • Regulation of beta-adrenergic receptors by phospholipid methylation. 
  • Regulation of rabbit myometrial alpha adrenergic receptors by estrogen and progesterone. 
  • Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. 
  • Resolution of beta-adrenergic receptor binding and adenylate cyclase activity by gel exclusion chromatography. 
  • Reversal of cardiac remodeling by modulation of adrenergic receptors: a new frontier in heart failure. 
  • Role of alpha 1 adrenoceptors in the turnover of phosphatidylinositol and of alpha 2 adrenoceptors in the regulation of cyclic AMP accumulation in hamster adipocytes. 
  • Role of phosphorylation in desensitization of the beta-adrenoceptor. 
  • Role of receptor mechanisms in the adaptive response to habitual exercise. 
  • Selective alteration in high affinity agonist binding: a mechanism of beta-adrenergic receptor desensitization. 
  • Selective alterations of regional beta-adrenergic receptor binding in the kindling model of epilepsy. 
  • Selectivity of dobutamine for adrenergic receptor subtypes: in vitro analysis by radioligand binding. 
  • Separation of solubilized alpha and beta adrenergic receptors by affinity chromatography. 
  • Seven-transmembrane-spanning receptors and heart function. 
  • Slowly reversible binding of catecholamine to a nucleotide-sensitive state of the beta-adrenergic receptor. 
  • Solubilization and characterization of the beta-adrenergic receptor binding sites of frog erythrocytes. 
  • Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors and adenylate cyclase. 
  • Structure and biological activity of (-)-[3H]dihydroalprenolol, a radioligand for studies of beta-adrenergic receptors. 
  • Structure and function of the adrenergic receptor family. 
  • Structure of the adrenergic and related receptors. 
  • Structure-activity relationships of adenylate cyclase-coupled beta adrenergic receptors: determination by direct binding studies. 
  • Subclassification of alpha-adrenergic receptors by direct binding studies. 
  • Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro. 
  • Subtype specificity of alpha-adrenergic receptors in rat heart. 
  • Sympathetic neural influence on norepinephrine vasoconstriction in brain vessels. 
  • Synthesis of iodine-125 labeled (+/-)-15-(4-azidobenzyl)carazolol: a potent beta-adrenergic photoaffinity probe. 
  • Techniques for the study of the biochemical basis of drug action. 
  • Temperature immutability of adenyl cyclase-coupled beta adrenergic receptors. 
  • The Gordon Wilson lecture. Adrenergic receptors: regulation at the biochemical, physiological and clinical levels. 
  • The beta 1-adrenergic receptor of the turkey erythrocyte. Molecular heterogeneity revealed by purification and photoaffinity labeling. 
  • The beta-adrenergic receptor and adenylate cyclase. 
  • The beta-adrenergic receptor. 
  • The beta-adrenergic receptor: rapid purification and covalent labeling by photoaffinity crosslinking. 
  • The cardiac beta-adrenergic receptor. Structural similarities of beta 1 and beta 2 receptor subtypes demonstrated by photoaffinity labeling. 
  • The guanine nucleotide regulatory protein-coupled receptors for nucleosides, nucleotides, amino acids and amine neurotransmitters. 
  • The human placenta--a rich source of beta-adrenergic receptors: characterization of the receptors in particulate and solubilized preparations. 
  • The identification of adrenergic receptors in human pial membranes. 
  • The impact of aging on adrenergic receptor function: clinical and biochemical aspects. 
  • The mammalian beta-adrenergic receptors. 
  • The noradrenergic system in cultured aggregates of fetal rat brain cells: morphology of the aggregates and pharmacological indices of noradrenergic neurons. 
  • Thyroid hormone modulation of agonist--beta-adrenergic receptor interactions in the rat heart. 
  • Thyroid hormone regulation of alpha-adrenergic receptors: studies in rat myocardium. 
  • Thyroid hormone regulation of beta-adrenergic receptor number. 
  • Thyroxine and propylthiouracil effects on alpha- and beta-adrenergic receptor number, ATPase activities, and sialic acid content of rat cardiac membrane vesicles. 
  • Topographic separation of adenylate cyclase and hormone receptors in the plasma membrane of toad erythrocyte ghosts. 
  • Transgenic manipulation of myocardial G protein-coupled receptors and receptor kinases. 
  • Undernutrition and overnutrition in the neonatal rat: long-term effects on noradrenergic pathways in brain regions. 
  • Use of cell fusion techniques to probe the mechanism of catecholamine-induced desensitization of adenylate cyclase in frog erythrocytes. 
  • Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. 
  • [3H]Dihydroergocryptine binding to alpha adrenergic receptors in canine aortic membranes. 
  • [3H]WB4101--caution about its role as an alpha-adrenergic subtype selective radioligand. 
  • [3H]dihydroergocryptine binding in rat brain. 
  • alpha-Adrenergic receptors in human adipocyte membranes: direct determination by [3H]yohimbine binding. 
  • alpha-Adrenergic receptors in rat parotid cells. I. Correlation of [3H]dihydroergocryptine binding and catecholamine-stimulated potassium efflux. 
  • alpha-Adrenergic receptors in rat parotid cells. II. Desensitization of receptor binding sites and potassium release. 
  • beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling. 
  • beta-Adrenergic receptor regulation by agonists and membrane depolarization in rat brain slices. 
  • beta-adrenergic receptors in brown adipose tissue: identification by (-)[3H]dihydroalprenolol binding. 
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  Keywords of People

  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute