Receptors, Cell Surface

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  Subject Areas on Research

  • (3H)norepinephrine binding: unrelated to catechol-O-methyl transferase. 
  • (Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling. 
  • A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. 
  • A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants. 
  • A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. 
  • A carcinoembryonic antigen (CEA) binding protein from ascites influences CEA uptake by macrophages. 
  • A cell surface receptor mediates extracellular Ca(2+) sensing in guard cells. 
  • A chemoattractant receptor on macrophages exists in two affinity states regulated by guanine nucleotides. 
  • A family of candidate taste receptors in human and mouse. 
  • A family of receptors coupled to guanine nucleotide regulatory proteins. 
  • A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic. 
  • A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration. 
  • A kinetic analysis using fractals of cellular analyte-receptor binding and dissociation. 
  • A model system for the biochemical study of luteinizing hormone/chorionic gonadotropin receptor synthesis. 
  • A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme. 
  • A novel leptin receptor isoform in rat. 
  • A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC. 
  • A phase I first-in-human study of TRC105 (Anti-Endoglin Antibody) in patients with advanced cancer. 
  • A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. 
  • Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells. 
  • Abundance of infiltrating CD163+ cells in the retina of postmortem eyes with dry and neovascular age-related macular degeneration. 
  • Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5. 
  • Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. 
  • Adenovirus-mediated antisense urokinase-type plasminogen activator receptor gene transfer reduces tumor cell invasion and metastasis in non-small cell lung cancer cell lines. 
  • Adhesin presentation in bacteria requires molecular chaperones and ushers. 
  • Adhesion mediated by bonds in series. 
  • Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration. 
  • Aging alters macrophage properties in human skeletal muscle both at rest and in response to acute resistance exercise. 
  • Allovalency revisited: an analysis of multisite phosphorylation and substrate rebinding. 
  • Alpha 1-adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures. 
  • Alpha 2-macroglobulin is a binding protein for basic fibroblast growth factor. 
  • Altered activity of the nucleotide regulatory site in the parathyroid hormone-sensitive adenylate cyclase from the renal cortex of a patient with pseudohypoparathyroidism. 
  • Aluminum is a weak agonist for the calcium-sensing receptor. 
  • Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism. 
  • Amphotericin B alters the affinity and functional activity of the oligopeptide chemotactic factor receptor on human polymorphonuclear leukocytes. 
  • An entirely cell-based system to generate single-chain antibodies against cell surface receptors. 
  • An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis. 
  • An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina. 
  • An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. 
  • Analysis of protein binding to receptor-doped lipid monolayers by Monte Carlo simulation. 
  • Analysis of the mouse transcriptome for genes involved in the function of the nervous system. 
  • Another cystic mystery solved. 
  • Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction. The GUSTO-III Platelet Substudy. 
  • Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. 
  • Apoptosis and NF-kappa B: the FADD connection. 
  • Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors. 
  • Arresting developments in heptahelical receptor signaling and regulation. 
  • Artificial receptors for the recognition of phosphorylated molecules. 
  • Assessment of the genetic variance of late-onset Alzheimer's disease. 
  • Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1. 
  • Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. 
  • Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. 
  • Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis. 
  • Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells. 
  • Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. 
  • Auxin perception and downstream events. 
  • B-cell homeostasis: digital survival or analog growth? 
  • BMP4 is essential for lens induction in the mouse embryo. 
  • Barbiturate and GABA receptors coupled to benzodiazepine receptors in rat hippocampal formation: a radiohistochemical study. 
  • Benzodiazepine receptor declines in hippocampal formation following limbic seizures. 
  • Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i). 
  • Beta-Arrestins: new roles in regulating heptahelical receptors' functions. 
  • Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. 
  • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. 
  • Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. 
  • Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis. 
  • Bimodular auxin response controls organogenesis in Arabidopsis. 
  • Biochemical actions of follice-stimulating hormone in the sertoli cell of the rat testis. 
  • Biochemical fractionation and assembly of the membrane components that mediate nascent chain targeting and translocation. 
  • Biochemical mechanisms of hormone receptor-effector coupling. Introduction. 
  • Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure. 
  • Biosensors and biochips: advances in biological and medical diagnostics. 
  • Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human keratinocytes and the effect of retinoic acid. 
  • Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer. 
  • Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats. 
  • CD163+ macrophages infiltrate axon bundles of postmortem optic nerves with glaucoma. 
  • CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. 
  • CD6-ligand interactions: a paradigm for SRCR domain function? 
  • CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer. 
  • COI1 is a critical component of a receptor for jasmonate and the bacterial virulence factor coronatine. 
  • COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. 
  • CUBN is a gene locus for albuminuria. 
  • Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites. 
  • Calcium-sensing receptor activation of rho involves filamin and rho-guanine nucleotide exchange factor. 
  • Calmodulin as a mediator of hormone action and cell regulation. 
  • Cardiac hypertrophy: role of G protein-coupled receptors. 
  • Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations. 
  • Cdc42p, GTP hydrolysis, and the cell's sense of direction. 
  • Cell surface annexin II is a high affinity receptor for the alternatively spliced segment of tenascin-C. 
  • Cell-surface co-receptors: emerging roles in signaling and human disease. 
  • Cell-surface receptor shedding: a means of regulating function. 
  • Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism. 
  • Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes. 
  • Changes in (125I) labeled human chorionic gonadotropin (hCG) binding to porcine granulosa cells during follicle development and cell culture. 
  • Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors. 
  • Characterization of an oligopeptide chemoattractant receptor on human blood monocytes using a new radioligand. 
  • Characterization of kinectin, a kinesin-binding protein: primary sequence and N-terminal topogenic signal analysis. 
  • Characterization of murine peritoneal macrophage receptors for fibrin(ogen) degradation products. 
  • Characterization of platelet-derived growth factor and platelet-derived growth factor receptor expression in asbestos-induced rat mesothelioma. 
  • Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. 
  • Characterization of the plasminogen receptors of normal and rheumatoid arthritis human synovial fibroblasts. 
  • Chemoattractant receptor affinity reflects its ability to transduce different biological responses. 
  • Chemoattractant receptor functions in human polymorphonuclear leukocytes are divergently altered by membrane fluidizers. 
  • Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage. 
  • Chemoreception scientists gather under the Florida sun: The 31st Annual Association for Chemoreception Sciences meeting. 
  • Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors. 
  • Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization. 
  • Clathrin-coated vesicle assembly polypeptides: physical properties and reconstitution studies with brain membranes. 
  • Clinical heterogeneity in hereditary haemorrhagic telangiectasia: are pulmonary arteriovenous malformations more common in families linked to endoglin? 
  • Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma. 
  • Cloning and structural analysis of the human c-kit gene. 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Commentary. Molecular pharmacology of beta-adrenergic receptors--a status report. 
  • Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer. 
  • Comparative analysis of quantitative trait loci controlling glucosinolates, myrosinase and insect resistance in Arabidopsis thaliana. 
  • Comparative analysis of type 2b von Willebrand disease mutations: implications for the mechanism of von Willebrand factor binding to platelets. 
  • Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy. 
  • Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders. 
  • Complex binding of L-[3H]glutamate to hippocampal synaptic membranes in the absence of sodium. 
  • Complexes between serpins and inactive proteinases are not thermodynamically stable but are recognized by serpin receptors. 
  • Computational design of a Zn2+ receptor that controls bacterial gene expression. 
  • Computational design of receptors for an organophosphate surrogate of the nerve agent soman. 
  • Concerning the hormonal regulation of androgen binding protein in rat testis. 
  • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. 
  • Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation. 
  • Controlled targeting of liposomal doxorubicin via the folate receptor in vitro. 
  • Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium. 
  • Correlating notch signaling with thymocyte maturation. 
  • Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses. 
  • Coupled events in the early biochemical actions of FSH on the Sertoli cells of the testis. 
  • Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways. 
  • Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. 
  • Dendritic cells stimulated with Actinobacillus actinomycetemcomitans elicit rapid gamma interferon responses by natural killer cells. 
  • Desensitization of G protein-coupled receptors. 
  • Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. 
  • Developmental coordination of luteinizing hormone/human chorionic gonadotropin (hCG) receptors and acute hCG responsiveness in cultured and freshly harvested porcine granulosa cells. 
  • Developmental signalling. Sorting out the signals. 
  • Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma. 
  • Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. 
  • Differential effects of cholera toxin on guanine nucleotide regulation of beta-adrenergic agonist high affinity binding and adenylate cyclase activation in frog erythrocyte membranes. 
  • Differential gene expression in the distal tip endoderm of the embryonic mouse lung. 
  • Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain. 
  • Differential regulation of accessory mitogenic signaling receptors by the T cell antigen receptor. 
  • Differential regulation of formyl peptide and platelet-activating factor receptors. Role of phospholipase Cbeta3 phosphorylation by protein kinase A. 
  • Differential responsiveness of MCF-7 human breast cancer cell line stocks to the pineal hormone, melatonin. 
  • Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression. 
  • Differential screening of a human chromosome 3 library identifies hepatocyte growth factor-like/macrophage-stimulating protein and its receptor in injured lung. Possible implications for neuroendocrine cell survival. 
  • Differentiation of human T lymphocytes: II. Phenotypic difference in skin and blood malignant T-cells in cutaneous T-cell lymphoma. 
  • Diffusion of low density lipoprotein-receptor complex on human fibroblasts. 
  • Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor. 
  • Direct antidiabetic effect of leptin through triglyceride depletion of tissues. 
  • Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras. 
  • Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. 
  • Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family. 
  • Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program. 
  • Down regulation of macrophage mannose/N-acetylglucosamine receptors by elevated glucose concentrations. 
  • Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. 
  • Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean. 
  • Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization. 
  • Dysregulation of the microvasculature in nonlesional non-sun-exposed skin of patients with lupus nephritis. 
  • EPCR knockout: inflaming the discussion. 
  • Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling. 
  • Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36. 
  • Effect of membrane fluidizers on the number and affinity of chemotactic factor receptors on human polymorphonuclear leukocytes. 
  • Effect of modulating macrophage phenotype on peripheral nerve repair 
  • Effects of partially and more highly purified platelet-derived growth factor preparations on luteinizing hormone receptor induction in granulosa cell cultures. 
  • Elucidating the role of plexin D1 in body fat distribution and susceptibility to metabolic disease using a zebrafish model system. 
  • Emerging paradigms, platforms, and unifying themes in biomarker science. 
  • Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. 
  • Endoglin deficiency impairs stroke recovery. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells. 
  • Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC. 
  • Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis. 
  • Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. 
  • Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. 
  • Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency. 
  • Enhancing immunogenicity by CpG DNA. 
  • Erythrocyte blood group antigens: not so simple after all. 
  • Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. 
  • Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors. 
  • Evidence that Substantia Nigra is crucial to neural network of kindled seizures. 
  • Evidence that a beta-adrenergic receptor-associated guanine nucleotide regulatory protein conveys guanosine 5'-O-(3-thiotriphosphate)- dependent adenylate cyclase activity. 
  • Evolution of a malaria resistance gene in wild primates. 
  • Excitatory amino acid neurotoxins: selectivity, specificity, and mechanisms of action. Based on an NRP one-day conference held June 30, 1980. 
  • Excitatory amino acid receptors in epilepsy. 
  • Expanding roles for beta-arrestins as scaffolds and adapters in GPCR signaling and trafficking. 
  • Expression analysis of endoglin missense and truncation mutations: insights into protein structure and disease mechanisms. 
  • Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1. 
  • Expression cloning and characterization of the TGF-beta type III receptor. 
  • Expression cloning of TGF-beta receptors. 
  • Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. 
  • Expression cloning of type 2 angiotension II receptor reveals a unique class of seven-transmembrane receptors. 
  • Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated. 
  • Expression of EGF receptor and transferrin by F9 and PC13 teratocarcinoma cells. 
  • Expression of Toll-like receptors in human endometrial epithelial cells and cell lines. 
  • Expression of endothelial protein C receptor in cortical peritubular capillaries associates with a poor clinical response in lupus nephritis. 
  • Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture. 
  • Expression of the cell adhesion molecule CD44 in gastric adenocarcinomas. 
  • FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. 
  • Factors affecting Sertoli cell function in the testis. 
  • Female steroid hormones and target cell nuclei. 
  • Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells. 
  • Flavonoids. 8. Synthesis and antifertility and estrogen receptor binding activities of coumarins and delta3-isoflavenes. 
  • Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein. 
  • Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts. 
  • Folate targeting of drug carriers: a mathematical model. 
  • Follicle stimulating hormone regulation of protein kinase activity and protein synthesis in testis. 
  • Follicle-stimulating hormone, the Sertoli cell, and spermatogenesis. 
  • Follicle-stimulating hormone-mediated induction of functional luteinizing hormone/human chorionic gonadotropin receptors during monolayer culture of porcine granulosa cells. 
  • Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch. 
  • Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex. 
  • Functional modification of the guanine nucleotide regulatory protein after desensitization of turkey erythrocytes by catecholamines. 
  • Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site. 
  • G protein-coupled receptor kinases. 
  • G protein-coupled receptor kinases. 
  • G protein-coupled receptors and receptor kinases: from molecular biology to potential therapeutic applications. 
  • G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. 
  • G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization. 
  • G proteins control diverse pathways of transmembrane signaling. 
  • G proteins. The subunit story thickens. 
  • G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism. 
  • G-protein-coupled receptor function in heart failure. 
  • G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors. 
  • G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins. 
  • GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation. 
  • GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling. 
  • GRP78: a multifunctional receptor on the cell surface. 
  • Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems. 
  • Gene expression profiling of microsatellite unstable and microsatellite stable endometrial cancers indicates distinct pathways of aberrant signaling. 
  • Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. 
  • Genetic abnormalities in hereditary hemorrhagic telangiectasia. 
  • Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis. 
  • Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene. 
  • Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes. 
  • Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes. 
  • Genetic variation in the leptin receptor gene and obesity in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. 
  • Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes. 
  • Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. 
  • Genome sequencing unveils a regulatory landscape of platelet reactivity. 
  • Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. 
  • Genome-wide association studies in asthma: what they really told us about pathogenesis. 
  • Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 
  • Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. 
  • Gibberellin-GID1-DELLA: a pivotal regulatory module for plant growth and development. 
  • Gibberellin-induced DELLA recognition by the gibberellin receptor GID1. 
  • Glomerular atrial natriuretic factor receptors in primary glomerulopathies: studies on human renal biopsies. 
  • Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders. 
  • Gorlin syndrome and desmoplastic medulloblastoma: Report of 3 cases with unfavorable clinical course and novel mutations. 
  • Granulosa cell differentiation in vitro: effect of insulin on growth and functional integrity. 
  • Growth factor control of extracellular proteolysis. 
  • Growth factors modulate gonadotropin receptor induction in granulosa cell cultures. 
  • Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes. 
  • Guanylate cyclase 1 relies on rhodopsin for intracellular stability and ciliary trafficking. 
  • Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate. 
  • Hedgehog signaling maintains resident hepatic progenitors throughout life. 
  • Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. 
  • Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation. 
  • Hepatic prolactin binding in female Sprague-Dawley rats fed a diet high in corn oil. 
  • Hepatocyte receptors for antithrombin III-proteinase complexes. 
  • Heptahelical receptor signaling: beyond the G protein paradigm. 
  • Hereditary haemorrhagic telangiectasia: a questionnaire based study to delineate the different phenotypes caused by endoglin and ALK1 mutations. 
  • Hereditary hemorrhagic telangiectasia: two distinct ENG deletions in one family. 
  • Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. 
  • Heterogeneity and probabilistic binding contributions to receptor-mediated cell detachment kinetics. 
  • Heterogeneity in the hormonal responsiveness of clones derived from the 13762NF rat mammary tumor. 
  • Heterogeneity of platelet aggregation and major surface receptor expression in patients with acute myocardial infarction. 
  • High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor. 
  • Hormone receptor complexes and their modulation of membrane function. 
  • Hormones, receptors, and cyclic AMP: their role in target cell refractoriness. 
  • Human UDP-galactose 4'-epimerase (GALE) is required for cell-surface glycome structure and function. 
  • Human leukemia cell lines with comparable receptor binding characteristics but different phenotypic responses to phorbol diesters. 
  • Human platelet adenylate cyclase: delineation of distinct stimulatory and inhibitory guanine nucleotide regulatory pathways. 
  • Human splenic sinusoidal lining cells express antigens associated with monocytes, macrophages, endothelial cells, and T lymphocytes. 
  • Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex. 
  • Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. 
  • Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles. 
  • Hypocotyl transcriptome reveals auxin regulation of growth-promoting genes through GA-dependent and -independent pathways. 
  • Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes. 
  • ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells. 
  • Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato. 
  • Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. 
  • Identification of a 43-kilodalton human T lymphocyte membrane protein as a receptor for pertussis toxin. 
  • Identification of additional members of human G-protein-coupled receptor kinase multigene family. 
  • Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor. 
  • Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia. 
  • Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion. 
  • Importance of race on breast cancer survival. 
  • Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study. 
  • Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus. 
  • Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4. 
  • Induction of selective biological responses to chemoattractants in a human monocyte-like cell line. 
  • Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation. 
  • Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth. 
  • Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis. 
  • Innate immunity influences long-term outcomes after human lung transplant. 
  • Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae. 
  • Interaction of the Shiga-like toxin type 1 B-subunit with its carbohydrate receptor. 
  • Interactions between propofol and lipid mediator receptors: inhibition of lysophosphatidate signaling. 
  • Intestinal Inflammation Promotes MDL-1+ Osteoclast Precursor Expansion to Trigger Osteoclastogenesis and Bone Loss. 
  • Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee. 
  • Intravascular bronchioloalveolar tumor of the lung presenting as pulmonary thromboembolic disease and pulmonary hypertension. 
  • Introduction to 'A multitargeted approach: clinical advances in the treatment of solid tumours'. 
  • Invasion of human vascular endothelial cells by Actinobacillus actinomycetemcomitans via the receptor for platelet-activating factor. 
  • Investigation of Notch3 as a candidate gene for bipolar disorder using brain hyperintensities as an endophenotype. 
  • Involvement of the mt1 melatonin receptor in human breast cancer. 
  • Isolated hormone receptors: physiologic and clinical implications. 
  • JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. 
  • Kindled seizures result in decreased responsiveness of benzodiazepine receptors to gamma-aminobutyric acid (GABA). 
  • Knock-down of LAR protein tyrosine phosphatase induces insulin resistance. 
  • L-[3H]Glutamate binding to hippocampal synaptic membranes: two binding sites discriminated by their differing affinities for quisqualate. 
  • LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. 
  • Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease. 
  • Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. 
  • Leptin regulates proinflammatory immune responses. 
  • Letter: Insulin activity: the solid matrix. 
  • Life is sweet: the cell biology of glycoconjugates. 
  • Light chains are a ligand for megalin. 
  • Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma. 
  • LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo. 
  • Lymphangitis after self-administration of lipopolysaccharide. 
  • Lysophosphatidic acid receptor signaling in mammalian retinal pigment epithelial cells. 
  • Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut. 
  • M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1. 
  • Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results. 
  • Macrophage-stimulating protein and its receptor in non-small-cell lung tumors: induction of receptor tyrosine phosphorylation and cell migration. 
  • Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma. 
  • Matrix gla protein is regulated by a mechanism functionally related to the calcium-sensing receptor. 
  • Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis. 
  • Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions. 
  • Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase. 
  • Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases. 
  • Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors. 
  • Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of Mac-1(CD11b/CD18) and urokinase receptor (CD87). 
  • Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2. 
  • Megalin mediates renal uptake of heavy metal metallothionein complexes. 
  • Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation. 
  • Melatonin enhancement of splenocyte proliferation is attenuated by luzindole, a melatonin receptor antagonist. 
  • Melatonin synergizes with retinoic acid in the prevention and regression of breast cancer. 
  • Melatonin: a chemical photoperiodic signal with clinical significance in humans. 
  • Membrane association of the myristoylated alanine-rich C kinase substrate (MARCKS) protein appears to involve myristate-dependent binding in the absence of a myristoyl protein receptor. 
  • Membrane receptors as general markers for plasma membrane isolation procedures. The use of 125-I-labeled wheat germ agglutinin, insulin, and cholera toxin. 
  • Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. 
  • Methylxanthines as adenosine receptor antagonists. 
  • Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II. 
  • Mitogenic signaling via G protein-coupled receptors. 
  • Model systems for the study of seven-transmembrane-segment receptors. 
  • Models of drug interaction with the sodium channel. 
  • Modulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer. 
  • Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody. 
  • Modulation of platelet shape and membrane receptor binding by Ca2+-calmodulin complex. 
  • Modulation of platelet surface adhesion receptors during cardiopulmonary bypass. 
  • Molecular and cellular mechanisms of leukocyte chemotaxis. 
  • Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis. 
  • Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator. 
  • Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*. 
  • Molecular mechanisms of G protein-coupled receptor desensitization and resensitization. 
  • Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization. 
  • Molecular mechanisms of coupling in hormone receptor-adenylate cyclase systems. 
  • Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications. 
  • Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. 
  • Monocyte adhesion in patients with bone marrow fibrosis is required for the production of fibrogenic cytokines. Potential role for interleukin-1 and TGF-beta. 
  • Monocyte chemotactic peptide receptor. Functional characteristics and ligand-induced regulation. 
  • Monolayer growth and differentiated function of porcine and rat granulosa cells following cryopreservation. 
  • Morphological and biochemical properties of a new human breast cancer cell line. 
  • Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity. 
  • Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand. 
  • Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles. 
  • Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation. 
  • Myeloma light chains are ligands for cubilin (gp280). 
  • N-Formylmethionyl peptide receptors on equine leukocytes initiate secretion but not chemotaxis. 
  • NMDA and non-NMDA receptor-mediated increase of c-fos mRNA in dentate gyrus neurons involves calcium influx via different routes. 
  • Nascent secretory chain binding and translocation are distinct processes: differentiation by chemical alkylation. 
  • Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1. 
  • Neuronal IL-4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia. 
  • New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. 
  • NgBR is essential for endothelial cell glycosylation and vascular development. 
  • Niche-specific contribution to streptococcal virulence of a MalR-regulated carbohydrate binding protein. 
  • Non-equivalent roles of Drosophila Frizzled and Dfrizzled2 in embryonic wingless signal transduction. 
  • Notch 1 signaling regulates peripheral T cell activation. 
  • Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism. 
  • Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer. 
  • Nuclear hormone receptors as targets for new drug discovery. 
  • Nutritional regulation of the placental lactogen receptor in fetal liver: implications for fetal metabolism and growth. 
  • O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines. 
  • OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype. 
  • Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1. 
  • Optimization of immunolabeled plasmonic nanoparticles for cell surface receptor analysis. 
  • Overexpression of decoy receptor 3 in precancerous lesions and adenocarcinoma of the esophagus. 
  • Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinoma. 
  • Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomas. 
  • Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion. 
  • Overexpression of the MT1 melatonin receptor in MCF-7 human breast cancer cells inhibits mammary tumor formation in nude mice. 
  • PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized alpha 2-macroglobulin. 
  • PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer. 
  • Patched-one or smoothened gene mutations are infrequent in chondrosarcoma. 
  • Pathophysiology and pharmacology of G protein-coupled receptors in the heart. 
  • Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling. 
  • Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats. 
  • Peripheral metabolic actions of leptin. 
  • Pharmacologic manipulation of leukocyte chemotaxis. Present knowledge and future trends. 
  • Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts. 
  • Phenylalanine 30 plays an important role in receptor binding of verotoxin-1. 
  • Phorbol diester-induced H2O2 production by peritoneal macrophages. Different H2O2 production by macrophages from normal and BCG-infected mice despite comparable phorbol diester receptors. 
  • Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. 
  • Physiological receptors as physicochemical entities. 
  • Physiopathologic role of cubilin and megalin. 
  • Pilus and nonpilus bacterial adhesins: assembly and function in cell recognition. 
  • Placental lactogen and GH receptors in sheep liver: striking differences in ontogeny and function. 
  • Placental lactogen receptors in maternal sheep liver: effects of fasting and refeeding. 
  • Placental lactogen-binding sites in isolated fetal fibroblasts: characterization, processing, and regulation. 
  • Plasma membrane receptors. 
  • Plasmin binding to the plasminogen receptor enhances catalytic efficiency and activates the receptor for subsequent ligand binding. 
  • Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum. 
  • Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors. 
  • Platelet-derived growth factor enhances granulosa cell luteinizing hormone receptor induction by follicle-stimulating hormone and serum. 
  • Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies. 
  • Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. 
  • Posttranscriptional generation of macromolecular complexes. 
  • Potential treatment for clubfeet based on growth factor blockade. 
  • Preparation of inverted plasma membrane vesicles from isolated adipocytes. 
  • Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia. 
  • Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure. 
  • Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma. 
  • Prognostic utility of novel biomarkers of cardiovascular stress in patients with aortic stenosis undergoing valve replacement. 
  • Protection against Escherichia coli-induced urinary tract infections with hybridoma antibodies directed against type 1 fimbriae or complementary D-mannose receptors. 
  • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. 
  • Protein kinase C delta (PKCdelta) is required for protein tyrosine phosphatase mu (PTPmu)-dependent neurite outgrowth. 
  • Protein phosphorylation: hormones, drugs, and bioregulation. 
  • Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion. 
  • Proteolysis-independent downregulation of DELLA repression in Arabidopsis by the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1. 
  • Proteolytic domains of the epidermal growth factor receptor of human placenta. 
  • Pseudo-von Willebrand disease: a mutation in the platelet glycoprotein Ib alpha gene associated with a hyperactive surface receptor. 
  • Quantifying ligand bias at seven-transmembrane receptors. 
  • Quantitative analysis of the calcium-sensing receptor messenger RNA in parathyroid adenomas. 
  • RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses. 
  • ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. 
  • Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. 
  • Receptor Switching in Newly Evolved Adeno-associated Viruses. 
  • Receptor binding sites for atrial natriuretic factor are expressed by brown adipose tissue. 
  • Receptor binding, endocytosis, and mitogenesis of insulin-like growth factors I and II in fetal rat brain neurons. 
  • Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). 
  • Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages. 
  • Receptor regulation: beta-arrestin moves up a notch. 
  • Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root. 
  • Receptor-mediated endocytosis of carcinoembryonic antigen by rat alveolar macrophages in vitro. 
  • Receptor-mediated monocytoid differentiation of human promyelocytic cells by tumor necrosis factor: synergistic actions with interferon-gamma and 1,25-dihydroxyvitamin D3. 
  • Receptors for bitter and sweet taste. 
  • Receptors for maleylated proteins regulate secretion of neutral proteases by murine macrophages. 
  • Receptors on hepatocytes that bind ligands containing fucosyl alpha 1,3 N-acetylglucosamine linkages. 
  • Recombinant hirudin displaces human factor Xa from its endothelial binding sites. 
  • Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. 
  • Recovery and expression of messenger RNA from postmortem human brain tissue. 
  • Red blood cell surface adhesion molecules: their possible roles in normal human physiology and disease. 
  • Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye. 
  • Regulation of G protein-coupled receptor signaling by scaffold proteins. 
  • Regulation of TGF-β receptor hetero-oligomerization and signaling by endoglin. 
  • Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors. 
  • Regulation of expression of transcobalamin II receptor in the rat. 
  • Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins. 
  • Regulation of prostaglandin receptors by prostaglandins and guanine nucleotides in frog erythrocytes. 
  • Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation. 
  • Regulation of transmembrane signaling by receptor phosphorylation. 
  • Regulation of tyrosine kinase cascades by G-protein-coupled receptors. 
  • Regulatory mechanisms of a chemoattractant receptor on leukocytes. 
  • Research and clinical potential of receptor based radiopharmaceuticals. 
  • Response of blood leukocytes to thrombin receptor peptides. 
  • Retrospective family study of childhood medulloblastoma. 
  • RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage. 
  • Role for hedgehog pathway in regulating growth and function of invariant NKT cells. 
  • Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases. 
  • Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. 
  • Role of enzyme-bound 5,10-methenyltetrahydropteroylpolyglutamate in catalysis by Escherichia coli DNA photolyase. 
  • Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to platelet-activating factor. 
  • Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin. 
  • Role of platelet-activating factor in Chinese hamster ovary cell responses to cholera toxin. 
  • Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. 
  • Roles for netrin signaling outside of axon guidance: a view from the worm. 
  • SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction. 
  • SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. 
  • SMAD4 mutations found in unselected HHT patients. 
  • ST2 and mortality in non-ST-segment elevation acute coronary syndrome. 
  • ST2 in emergency department patients with noncardiac dyspnea. 
  • Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity. 
  • Scara5 is a ferritin receptor mediating non-transferrin iron delivery. 
  • Select de novo gene and protein expression during renal epithelial cell culture in rotating wall vessels is shear stress dependent. 
  • Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. 
  • Sensing of extracellular cations in CasR-deficient osteoblasts. Evidence for a novel cation-sensing mechanism. 
  • Separation of two thyrotropin binding components from porcine thyroid tissue by affinity chromatography: characterization of high and low affinity sites. 
  • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. 
  • Serpin receptor 1: a hepatic receptor that mediates the clearance of antithrombin III-proteinase complexes. 
  • Serum levels of HER-2 neu (C-erbB-2) correlate with overexpression of p185neu in human ovarian cancer. 
  • Serum levels of TARC, MDC, IL-10, and soluble CD163 in Hodgkin lymphoma: a SWOG S0816 correlative study. 
  • Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection. 
  • Seven-transmembrane receptors. 
  • Seven-transmembrane-spanning receptors and heart function. 
  • Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses. 
  • Signaling by the transforming growth factor-beta receptors. 
  • Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates. 
  • Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins. 
  • Simple biochemical pathways far from steady state can provide switchlike and integrated responses. 
  • Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function. 
  • Solubilization of a [3H]cimetidine binding site from rat brains. A clonidine-sensitive H-2 receptor subtype? 
  • Soluble CD14, CD163, and CD27 biomarkers distinguish ART-suppressed youth living with HIV from healthy controls. 
  • Soluble ST2 in ambulatory patients with heart failure: Association with functional capacity and long-term outcomes. 
  • Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis. 
  • Sonic hedgehog is required for cardiac outflow tract and neural crest cell development. 
  • Sour taste responses in mice lacking PKD channels. 
  • Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells. 
  • Specific interaction of 3H-FSH with rat testis binding sites. 
  • Specific photoaffinity labelling of inhibitory adenosine receptors. 
  • Specific receptors for phorbol diesters on freshly isolated human myeloid and lymphoid leukemia cells: comparable binding characteristics despite different cellular responses. 
  • Stability of nuclear triiodothyronine binding sites. 
  • Steroidal modulation of steroid secretion in vitro: an experimental approach to intra-follicular regulatory mechanisms. 
  • Structure and function of cholera toxin and hormone receptors. 
  • Subretinal Mononuclear Cells in Coats' Disease Studied with RPE65 and CD163: Evidence for Histiocytoid Pigment Epithelial Cells. 
  • Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro. 
  • Summary of Wenner-Gren international symposium receptor-receptor interactions among heptaspanning membrane receptors: from structure to function. 
  • Synthesis of 11 beta,13 beta- and 13 beta,16 beta-propano steroids: probes of hormonal activity. 
  • TGF beta signals through a heteromeric protein kinase receptor complex. 
  • Taste and pheromone perception in mammals and flies. 
  • Technical problems with agarose-hormone linkage. 
  • Techniques for the study of the biochemical basis of drug action. 
  • Testicular adenosine 3':5'-monophosphate-dependent protein kinase. Regulation by follicle-stimulating hormone. 
  • The 2.0 A crystal structure of a heterotrimeric G protein. 
  • The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. 
  • The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13. 
  • The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression. 
  • The Evolving Complexity of Treating Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer: Special Considerations in Older Breast Cancer Patients-Part I: Early-Stage Disease. 
  • The Evolving Complexity of Treating Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer: Special Considerations in Older Breast Cancer Patients-Part II: Metastatic Disease. 
  • The G protein-coupled receptor gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin. 
  • The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. 
  • The Gordon Wilson lecture. Adrenergic receptors: regulation at the biochemical, physiological and clinical levels. 
  • The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma. 
  • The IBR5 phosphatase promotes Arabidopsis auxin responses through a novel mechanism distinct from TIR1-mediated repressor degradation. 
  • The Trojan Horse of the microbiological arms race: phage-encoded toxins as a defence against eukaryotic predators. 
  • The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins. 
  • The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins. 
  • The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease. 
  • The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse. 
  • The clearance of human fibrinogen fragments X and Y in mice: a process mediated by the fragment D receptor. 
  • The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system. 
  • The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor. 
  • The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy. 
  • The distinct roles of JAM-A in reovirus pathogenesis. 
  • The effect of plating density on granulosa cell growth and differentiation in vitro. 
  • The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor. 
  • The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies. 
  • The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis. 
  • The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. 
  • The glycogenic effects of placental lactogen and growth hormone in ovine fetal liver are mediated through binding to specific fetal ovine placental lactogen receptors. 
  • The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells. 
  • The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins. 
  • The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes. 
  • The long-sought-after salicylic acid receptors. 
  • The mechanism of action of steroid hormones: a new twist to an old tale. 
  • The metabolism of luteinizing hormone. Plasma clearance, urinary excretion, and tissue uptake. 
  • The molecular genetics of hereditary hemorrhagic telangiectasia. 
  • The molecular mechanism and evolution of the GA-GID1-DELLA signaling module in plants. 
  • The mouse retinoid-X receptor-gamma gene: genomic organization and evidence for functional isoforms. 
  • The new biology of drug receptors. 
  • The oligopeptide chemotactic factor receptor on human polymorphonuclear leukocyte membranes exists in two affinity states. 
  • The placental lactogen receptor in maternal and fetal sheep liver: regulation by glucose and role in the pathogenesis of fasting during pregnancy. 
  • The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells). 
  • The role of Osteopontin in tumor metastasis. 
  • The role of Toll-like receptor 4 in environmental airway injury in mice. 
  • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. 
  • The role of cell surface receptors in the activation of human B cells by phosphorothioate oligonucleotides. 
  • The role of innate immunity in acute allograft rejection after lung transplantation. 
  • The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification. 
  • The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation. 
  • The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. 
  • The transmembrane hyaluronate receptor (CD44): multiple functions, multiple forms. 
  • The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells. 
  • Theoretical characterization of ion channel blockade. Competitive binding to periodically accessible receptors. 
  • Thrombin primes responsiveness of selective chemoattractant receptors at a site distal to G protein activation. 
  • Thrombin receptor. Variations on a theme. 
  • Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages. 
  • Thrombospondins as key regulators of synaptogenesis in the central nervous system. 
  • Tissue interactions pattern the mesenchyme of the embryonic mouse lung. 
  • To find the road traveled to tumor immunity: the trafficking itineraries of molecular chaperones in antigen-presenting cells. 
  • Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide. 
  • Toll-like receptors and allograft rejection. 
  • Toll-like receptors in the pathogenesis of human disease. 
  • Toxicology of environmental estrogens. 
  • Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. 
  • Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways. 
  • Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors. 
  • Transductional mechanisms of chemoattractant receptors on leukocytes. 
  • Transient receptor potential (TRP) channels and taste sensation. 
  • Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. 
  • Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages. 
  • Transplantation and autosomal recessive polycystic kidney disease. 
  • Transport of phosphorothioate oligonucleotides in kidney: implications for molecular therapy. 
  • Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA. 
  • Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. 
  • Two common endoglin mutations in families with hereditary hemorrhagic telangiectasia in the Netherlands Antilles: evidence for a founder effect. 
  • Type 1 fimbriated Escherichia coli-mast cell interactions in cystitis. 
  • U1 RNA induces innate immunity signaling. 
  • Ultrastructural and biochemical properties of the 120-kDa form of chick kinectin. 
  • Unexpected role of TRPC6 channel in familial nephrotic syndrome: does it have clinical implications? 
  • Use of multiple radioligands to characterize adenosine receptors in human placenta. 
  • Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease. 
  • Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. 
  • Vascular morphogenesis: tales of two syndromes. 
  • Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization. 
  • [Benzodiazepine receptors of the mouse glioblastoma cell line: the anomalous effect of gamma-aminobutyric acid on diazepam binding]. 
  • [Endocytosis and receptors: molecular and physiological aspects]. 
  • [Identification and evaluation of properties of benzodiazepine receptors of glial and neuronal fractions of human cerebral cortex]. 
  • [LMP-420, a new therapeutic approach for cerebral malaria?]. 
  • [Molecular mechanisms of the pharmacologic action of benzodiazepines]. 
  • [Vesicular flow in epithelial cells: physiopathologic importance of two multiligand receptors]. 
  • alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation. 
  • beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. 
  • beta-arrestins: traffic cops of cell signaling. 
  • beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy. 
  • αKlotho: FGF23 coreceptor and FGF23-regulating hormone. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • McCall, Shannon Jones, Associate Professor of Pathology, Pathology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Wax, Adam P., Professor of Biomedical Engineering, Biomedical Engineering
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology