Receptors, Fc
-
Subject Areas on Research
- A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic.
- A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.
- An analysis of the presence of Fc receptors on bone marrow lymphoblasts in acute lymphoblastic leukemia. A Pediatric Oncology Group study.
- Analysis of Fc gamma receptors on human peripheral blood leukocytes by flow microfluorometry. I. Receptor distributions on monocytes, T gamma cells and cells labeled with the 3Al anti-T cell monoclonal antibody.
- Antagonism of the Neonatal Fc Receptor as an Emerging Treatment for Myasthenia Gravis.
- Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses.
- Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
- Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay.
- CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo.
- CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques.
- Characterization of B-cell type chronic lymphocytic leukemia cells by surface markers and a monoclonal antibody.
- Circulating immune complexes in dermatologic disease.
- Circulating natural killer cell phenotypes in men and women with major depression. Relation to cytotoxic activity and severity of depression.
- Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1.
- Defective Fc-receptor functions associated with the HLA-B8/DRw3 haplotype: studies in patients with dermatitis herpetiformis and normal subjects.
- Donor type natural killer cells after haploidentical T cell-depleted bone marrow stem cell transplantation in a patient with adenosine deaminase-deficient severe combined immunodeficiency.
- Early activation and cell cycle entry of resting B cells after Fab-anti-Ig treatment: role of receptor crosslinking.
- Effectiveness and Safety of Romiplostim Among Patients with Newly Diagnosed, Persistent and Chronic Immune Thrombocytopenia in European Clinical Practice.
- Enhanced neonatal Fc receptor function improves protection against primate SHIV infection.
- Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry.
- Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001.
- Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission.
- Fc-mOX40L fusion protein produces complete remission and enhanced survival in 2 murine tumor models.
- Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE.
- GP120 specific cellular cytotoxicity in HIV-1 seropositive individuals. Evidence for circulating CD16+ effector cells armed in vivo with cytophilic antibody.
- Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease.
- Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice.
- Human T lymphocyte antigens as defined by monoclonal antibodies.
- Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.
- Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. I. Characterization of the lymphocyte subset reactive with B73.1.
- IRTA1 positivity helps identify a MALT-lymphoma-like subset of primary cutaneous marginal zone lymphomas, largely but not exclusively defined by IgM expression.
- IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis.
- IgA transcytosis and antigen recognition govern ovarian cancer immunity.
- IgE Fc receptor positive T and B lymphocytes in patients with the hyper IgE syndrome.
- IgE Fc receptor positive T, B and NK cells in patients with the hyper-IgE syndrome.
- In vitro studies of IgE synthesis by human blood mononuclear cells.
- Interactions of monomeric IgG bearing covalently bound C3b with polymorphonuclear leucocytes.
- Interferon suppresses pinocytosis but stimulates phagocytosis in mouse peritoneal macrophages: related changes in cytoskeletal organization.
- Lessons Learned Using Real-World Data to Emulate Randomized Trials: A Case Study of Treatment Effectiveness for Newly Diagnosed Immune Thrombocytopenia.
- Ligation of MHC class I and class II molecules can lead to heterologous desensitization of signal transduction pathways that regulate homotypic adhesion in human lymphocytes.
- Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection.
- Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model.
- Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections.
- Monocyte receptors for the Fc portion of IgG studies with monomeric human IgG1: normal in vitro expression of Fc gamma receptors in HLA-B8/Drw3 subjects with defective Fc gamma-mediated in vivo clearance.
- Neutrophil CD11b, L-selectin and Fc IgA receptors in patients with dermatitis herpetiformis.
- Phenotypic and functional characterization of human malignant T cells.
- Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture.
- Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes.
- Positively selected Leu-11a (CD16+) cells require the presence of accessory cells or factors for the lysis of herpes simplex virus-infected fibroblasts but not herpes simplex virus-infected Raji.
- Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification.
- Reticuloendothelial system fc receptor function in rheumatoid arthritis.
- Role of complement and Fc receptors in the pathogenesis of HIV-1 infection.
- Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus.
- Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes.
- Targeting Endoglin-Expressing Regulatory T Cells in the Tumor Microenvironment Enhances the Effect of PD1 Checkpoint Inhibitor Immunotherapy.
- The Roles of Host and Viral Antibody Fc Receptors in Herpes Simplex Virus (HSV) and Human Cytomegalovirus (HCMV) Infections and Immunity.
- The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors.
- The neonatal Fc receptor is a pan-echovirus receptor.
- The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice.
- The phenotype of human placental macrophages and its variation with gestational age.
- The road to romiplostim approval and beyond.
- Tumor necrosis factor-alpha induces increased hydrogen peroxide production and Fc receptor expression, but not increased Ia antigen expression by peritoneal macrophages.
- Tumor recognition and lytic competence of IL-2-activated lymphocytes: regulation of both antibody-independent and -dependent cellular cytotoxicity via P75 IL-2 receptor.
- Use of a thrombopoietin mimetic for chronic immune thrombocytopenic purpura in pregnancy.
-
Keywords of People
- Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Immunology